ObjectivesHealth and job satisfaction are key independent determinants of ability to work to older ages. We investigated the interaction of these two important factors on health-related job loss (HRJL) over 2 years of follow-up comparing male and female older workers.MethodsA population sample of adults aged 50–64 years, recruited from 24 English general practices in the Health and Employment After Fifty (HEAF) study, completed questionnaires at baseline with follow-ups at 12 and 24 months. Multiple-record...
Fri Sep 11, 2020 19:00
Conditions: Breast Cancer; NSCLC; Prostate Cancer; Head and Neck Cancer; Gastric Cancer; Esophageal Cancer; Ovarian CancerIntervention: Sponsor: Boryung Pharmaceutical Co., LtdRecruiting
Fri Sep 11, 2020 19:00
Conditions: Prostate Cancer; Recurrent Adenocarcinoma; Liver Cancer; Head and Neck CancerInterventions: Device: MRI Simulator; Radiation: Radiation TherapySponsor: Dana-Farber Cancer InstituteNot yet recruiting
Fri Sep 11, 2020 19:00
Conditions: Solid Tumor; Solid Carcinoma; Neoplasms; Uveal Melanoma; Squamous Cell Carcinoma of the Head and Neck; Squamous Cell Car. - Esophagus; Renal Cell Carcinoma; Colorectal Cancer; Advanced CancerIntervention: Drug: IMM-01Sponsor: Modulate Therapeutics LtdNot yet recruiting
Fri Sep 11, 2020 19:00
Conditions: Cervical Myelopathy; Cervical Radiculopathy; Spinal Stenosis; Spinal Disease; Spine Degeneration; Spine FusionIntervention: Other: Motion AnalysisSponsor: Zuyderland Medisch CentrumNot yet recruiting
Fri Sep 11, 2020 19:00
Publication date: Available online 10 September 2020Source: Human PathologyAuthor(s): Ronald Ghossein, Justine A. Barletta, Martin Bullock, Sarah J. Johnson, Kennichi Kakudo, Alfred K. Lam, Mufaddal T. Moonim, David N. Poller, Giovanni Tallini, R.Michael Tuttle, Bin Xu, Anthony J. Gill
Fri Sep 11, 2020 19:38
Publication date: Available online 11 September 2020Source: Brain Research BulletinAuthor(s): Do-Wan Lee, Dong-Cheol Woo, Hwon Heo, Kyung Won Kim, Jeong Kon Kim, Dong-Hoon Lee
Fri Sep 11, 2020 19:29
Journal of the American Chemical SocietyDOI: 10.1021/jacs.0c08243
Fri Sep 11, 2020 07:00
Journal of the American Chemical SocietyDOI: 10.1021/jacs.0c06932
Fri Sep 11, 2020 07:00
Journal of the American Chemical SocietyDOI: 10.1021/jacs.0c08035
Fri Sep 11, 2020 07:00
Journal of the American Chemical SocietyDOI: 10.1021/jacs.0c07792
Fri Sep 11, 2020 07:00
Journal of the American Chemical SocietyDOI: 10.1021/jacs.0c08389
Fri Sep 11, 2020 07:00
Publication date: Available online 11 September 2020Source: Journal of VoiceAuthor(s): Xueyan Li, Haizhou Wang, Wen Xu
Fri Sep 11, 2020 19:22
Publication date: Available online 11 September 2020Source: Journal of Human EvolutionAuthor(s): José-Miguel Tejero, Rivka Rabinovich, Reuven Yeshurun, Talia Abulafia, Ofer Bar-Yosef, Omry Barzilai, Mae Goder-Goldberger, Israel Hershkovitz, Ron Lavi, Maayan Shemer, Ofer Marder, Anna Belfer-Cohen
Fri Sep 11, 2020 19:22
Publication date: Available online 10 September 2020Source: Journal of ProteomicsAuthor(s): Hushuai Nie, Cheng Cheng, Jinping Hua
Fri Sep 11, 2020 19:14
Abstract Purpose The newly introduced erector spinae plane block (ESPB) has given anesthesiologists an alternative regional anesthetic technique for thoracic analgesia. Although ESPB and retrolaminar block (RLB) have similar puncture sites, no clinical study comparing ESPB and RLB has been reported. The aim of this study was to compare ESPB and RLB in terms of analgesic efficacy in the context of multimodal analgesia following breast...
Fri Sep 11, 2020 03:00
Stereotactic body radiation therapy (SBRT) is a radiation therapy technique for delivering high doses of external photon beams in few radiotherapy fractions [1]. Over the last few years SBRT has been shown to have strong curative potential with low toxicity rates [2] and nowadays it is more widely used for treating various types of cancer. Because of the high doses involved, SBRT deliveryrequireshigh dosimetric accuracy [1].
Fri Sep 11, 2020 03:00
Fri Sep 11, 2020 03:00
Publication date: November 2020Source: Medical Hypotheses, Volume 144Author(s): Andrey A. Venerin, Yana A. Venerina, Yury I. Alexandrov
Fri Sep 11, 2020 18:53
Publication date: Available online 10 September 2020Source: European Annals of Otorhinolaryngology, Head and Neck DiseasesAuthor(s): B. Fraysse, H. Thai Van, C. Collignon, B. Ruidavets
Fri Sep 11, 2020 18:45
Publication date: Available online 10 September 2020Source: European Journal of CancerAuthor(s): Ciro Pinelli, Giorgio Bogani, Jvan Casarin, Francesco Raspagliesi, Fabio Ghezzi
Fri Sep 11, 2020 18:33
Publication date: November–December 2020Source: Reports of Practical Oncology & Radiotherapy, Volume 25, Issue 6Author(s): Siddanna R. Palled, Nikhila K. Radhakrishna, Senthil Manikantan, Hashmath Khanum, Bindu K. Venugopal, Lokesh Vishwanath
Fri Sep 11, 2020 18:18
Publication date: September–October 2020Source: Reports of Practical Oncology & Radiotherapy, Volume 25, Issue 5Author(s):
Fri Sep 11, 2020 18:18
Publication date: Available online 10 September 2020Source: Ultrasound in Medicine & BiologyAuthor(s): Xiaomin Liu, Yinong Wang, Peizhen Zhang, Qing Wang, Qianjin Feng, Wufan Chen
Fri Sep 11, 2020 18:03
Abstract Oncogenic BRAF and NRAS mutations drive human melanoma initiation. We used transgenic zebrafish to model NRAS mutant melanoma and the rapid tumor onset allowed us to study candidate tumor suppressors. We identified P38α‐MAPK14 as a potential tumor suppressor in The Cancer Genome Atlas melanoma cohort of NRAS mutant melanomas, and overexpression significantly increased the time to tumor onset in transgenic zebrafish with NRAS‐driven melanoma. Pharmacological activation of P38α‐MAPK14 using...
Thu Sep 10, 2020 19:39
Abstract Purpose The relentless rise in antimicrobial resistance is a major societal challenge and requires, as part of its solution, a better understanding of bacterial colonization and infection. To facilitate this, we developed a highly efficient no-wash red optical molecular imaging agent that enables the rapid, selective, and specific visualization of Gram-positive bacteria through a bespoke optical fiber–based delivery/imaging...
Fri Sep 11, 2020 03:00
Abstract Adenoid tissue is considered as first line immunological defence mechanism in childhood. Adenoid hypertrophy in children is a common cause of nasal obstruction. It usually gets atrophied by puberty. Adenoid hypertrophy persisting in adults is a cause of nasal obstruction. A randomized prospective study was conducted on adult patients aged above 20 years of age presenting with bilateral nasal obstruction at a tertiary care hospital, for duration of 20 months from January...
Fri Sep 11, 2020 03:00
After admixture, recombination breaks down genomic blocks of contiguous ancestry. The break down of these blocks forms a new molecular clock, that ticks at a much faster rate than the mutation clock, enabling accurate dating of admixture events in the recent past. However, existing theory on the break down of these blocks, or the accumulation of delineations between blocks, so called junctions, has been limited to using regularly spaced markers on phased data. Here, we present an extension to the...
Sun Sep 13, 2020 03:00
Analyst, 2020, Accepted ManuscriptDOI: 10.1039/D0AN01641A, CommunicationQian-Qian Wang, Zheng-Qi Fang, Ya-Ting Wu, Min Zhang, Guoyue ShiIn this work, we fabricated a type of multiplexing upconversion nanoparticles (UCNPs). There are three fluorescence emission peaks when our UCNPs are excited by 980 and 808 nm lasers. These...The content of this RSS Feed (c) The Royal Society of Chemistry
Fri Sep 11, 2020 02:00
Publication date: Available online 11 September 2020Source: Journal of Surgical EducationAuthor(s): Emma R Lawrence, David Marzano, Anita Malone, Aimee Rolston
Fri Sep 11, 2020 17:26
Summary An inflammatory myofibroblastic tumor (IMT) is a rare invasive soft tissue mass with intramuscular penetration that is primarily treated via a surgical procedure. However, with unclear boundaries and a high rate of relapse, there is no standard treatment for recurrence or unresectable tumors. It is noteworthy that approximately half of IMTs harbor genetic rearrangements of the anaplastic lymphoma kinase (ALK). ALK inhibitors have been used successfully in the treatment...
Fri Sep 11, 2020 03:00
The pupil of the eye allows light to reach the retina, and a number of vision disorders are related to irregularities in the iris that surrounds the pupil. People with aniridia, for example, have some or all of the iris missing, exhibiting a large pupil that results in unfocused vision. Now, a collaboration between Imec, a Belgian research institution, Ghent University, Spain’s Instituto de Investigación Sanitaria Fundación Jiménez Díaz, and Holst Centre in The Netherlands, has led...
Fri Sep 11, 2020 17:03
Abstract In accordance with Article 6 of Regulation (EC) No 396/2005, the applicant BASF SE submitted a request to the competent national authority in Greece to modify the existing maximum residue level (MRL) for the active substance boscalid in granate apples/pomegranates. The data submitted in support of the request were found to be sufficient to derive an MRL proposal for pomegranates. Adequate analytical methods for enforcement are available to control the residues of boscalid in the commodity...
Fri Sep 11, 2020 12:37
Abstract The conclusions of EFSA following the peer review of the initial risk assessments carried out by the competent authorities of the rapporteur Member State Austria and co‐rapporteur Member State Italy for the pesticide active substance captan are reported and the confirmatory data following the Article 12 of Regulation (EC) No 396/2005 as well. The context of the peer review was that required by Commission Implementing Regulation (EU) No 844/2012, as amended by Commission Implementing Regulation...
Fri Sep 11, 2020 11:49
Abstract The conclusions of the EFSA following the peer review of the initial risk assessment carried out by the competent authority of the rapporteur Member State, Greece, for the pesticide active substance dithianon are reported. The context of the peer review was that requested by the European Commission following the submission and evaluation of confirmatory mammalian toxicology and residues data. The conclusions were reached on the basis of the evaluation of the representative uses of dithianon...
Thu Sep 10, 2020 16:45
Publication date: Available online 11 September 2020Source: Journal of Oral and Maxillofacial SurgeryAuthor(s): Kazem Khiabani, Majid Ahmadfar, Ali Labafchi, Mohammad Reza Gosheh, Sahand Samieirad
Fri Sep 11, 2020 17:22
Publication date: Available online 11 September 2020Source: Journal of Oral and Maxillofacial SurgeryAuthor(s): Samuel Macedo Costa, Roger Lanes silveira, Marcio Bruno Figueiredo Amaral
Fri Sep 11, 2020 17:22
Publication date: Available online 11 September 2020Source: Journal of Oral and Maxillofacial SurgeryAuthor(s): Masaru Konishi, Minoru Fujita, Kiichi Shimabukuro, Pongsapak Wongratwanich, Rinus Gerardus Verdonschot, Naoya Kakimoto
Fri Sep 11, 2020 17:22
Publication date: Available online 11 September 2020Source: Journal of Oral and Maxillofacial SurgeryAuthor(s): Benjamin Palla, Nicholas Callahan
Fri Sep 11, 2020 17:22
Publication date: Available online 10 September 2020Source: European Journal of Surgical OncologyAuthor(s): Dorian Culié, Julien Viotti, Anouchka Modesto, Renaud Schiappa, Emmanuel Chamorey, Olivier Dassonville, Gilles Poissonnet, Bruno Guelfucci, Alain Bizeau, Sebastien Vergez, Agnes Dupret-Bories, Renaud Garrel, Nicolas Fakhry, Laure Santini, Benjamin Lallemant, Guillaume Chambon, Anne Sudaka, Frederic Peyrade, Esma Saada-Bouzid, Karen Benezery
Fri Sep 11, 2020 17:11
Abstract Purpose The 8th edition of the American Joint Committee on Cancer (AJCC) staging led to a significant downstaging of well differentiated thyroid cancer patients. However, some patients who had been downstaged still experienced death. By using data from the thyroid cancer dataset of The Cancer Genome Atlas (TCGA), we aimed to find molecular features that could improve survival prediction. ...
Fri Sep 11, 2020 03:00
Publication date: Available online 11 September 2020Source: CortexAuthor(s): Paola Mengotti, Anne-Sophie Käsbauer, Gereon R. Fink, Simone Vossel
Fri Sep 11, 2020 16:56
Publication date: Available online 10 September 2020Source: CortexAuthor(s): Luigi Tamè, Matthew R. Longo
Fri Sep 11, 2020 16:56
Publication date: Available online 10 September 2020Source: CortexAuthor(s): Louise C. Barne, Floris P. de Lange, André M. Cravo
Fri Sep 11, 2020 16:56
Publication date: November 2020Source: Biomedicine & Pharmacotherapy, Volume 131Author(s): Daniel Crístian Ferreira Soares, Stephanie Calazans Domingues, Daniel Bragança Viana, Marli Luiza Tebaldi
Fri Sep 11, 2020 16:56
Publication date: November 2020Source: Biomedicine & Pharmacotherapy, Volume 131Author(s): Diego Bulcão Visco, Raul Manhães-de-Castro, Márcia Maria da Silva, Jakssuel Sebastion Dantas-Alves, Bárbara J.R. Costa-de-Santana, Glauber Rudá Feitoza Braz, Aline Isabel da Silva, Cláudia Jacques Lagranha, Ana Elisa Toscano
Fri Sep 11, 2020 16:56
Publication date: November 2020Source: Biomedicine & Pharmacotherapy, Volume 131Author(s): Xiaoyan Tian, Yuehui Liu, Zhi Wang, Shuhong Wu
Fri Sep 11, 2020 16:56
Publication date: November 2020Source: Biomedicine & Pharmacotherapy, Volume 131Author(s): Feng Cao, Le Zhu, Jing Zhang, Pawin Pongkorpsakol, Wei-Ting Kuo, Jerrold R. Turner, Qing Zhou, Yuan Wang, Feihu Chen, Yehai Liu, Li Zuo
Fri Sep 11, 2020 16:56
Publication date: November 2020Source: Biomedicine & Pharmacotherapy, Volume 131Author(s): Wei Zhou, Mengmeng Hu, Xiaohao Zang, Qifa Liu, Jiantang Du, Jingrong Hu, Lanyue Zhang, Zhiyun Du, Zhangmin Xiang
Fri Sep 11, 2020 16:56
Publication date: November 2020Source: Biomedicine & Pharmacotherapy, Volume 131Author(s): Yingran Liang, Bin Zheng, Jinghan Li, Jing Shi, Li Chu, Xue Han, Xi Chu, Xuan Zhang, Jianping Zhang
Fri Sep 11, 2020 16:56
Publication date: November 2020Source: Biomedicine & Pharmacotherapy, Volume 131Author(s): Cristina Rey-Blanes, Yalina Pérez-Portero, Humberto J. Morris-Quevedo, Virginia Casas, Roberto Abdala, Ana R. Quesada, Beatriz Martínez-Poveda, Miguel Ángel Medina
Fri Sep 11, 2020 16:56
Publication date: November 2020Source: Biomedicine & Pharmacotherapy, Volume 131Author(s): Jiajie Tu, Wei Huang, Weiwei Zhang, Jiawei Mei, Chen Zhu
Fri Sep 11, 2020 16:56
Publication date: November 2020Source: Biomedicine & Pharmacotherapy, Volume 131Author(s): E. Nasonov, M. Samsonov
Fri Sep 11, 2020 16:56
Publication date: November 2020Source: Biomedicine & Pharmacotherapy, Volume 131Author(s): Erastus Nembu Nembo, Jürgen Hescheler, Filomain Nguemo
Fri Sep 11, 2020 16:56
Publication date: November 2020Source: Biomedicine & Pharmacotherapy, Volume 131Author(s): Yujia Zhou, Ying Kong, Wenguo Fan, Tao Tao, Qin Xiao, Na Li, Xiao Zhu
Fri Sep 11, 2020 16:56
Publication date: November 2020Source: Biomedicine & Pharmacotherapy, Volume 131Author(s): Santwana Padhi, Amit Kumar Nayak, Anindita Behera
Fri Sep 11, 2020 16:56
Publication date: November 2020Source: Biomedicine & Pharmacotherapy, Volume 131Author(s): Kamran Mansouri, Mohsen Rastegari-Pouyani, Maryam Ghanbri-Movahed, Mehrnoush Safarzadeh, Sara Kiani, Zahra Ghanbari-Movahed
Fri Sep 11, 2020 16:56
Publication date: Available online 10 September 2020Source: Academic RadiologyAuthor(s): Elana B. Smith, Matthew Gellatly, Cody J. Schwartz, Sheryl Jordan
Fri Sep 11, 2020 16:40
Abstract The auditory system uses interaural time and level differences (ITD and ILD) as cues to localize and lateralize sounds. The availability of ITDs and ILDs in the auditory system is limited by neural phase-locking and by the head size, respectively. Although the frequency-specific limitations are well known, the relative contribution of ITDs and ILDs in individual frequency bands in broadband stimuli is unknown. To determine these relative contributions, or spectral weights,...
Fri Sep 11, 2020 03:00
Publication date: Available online 10 September 2020Source: Archives of Oral BiologyAuthor(s): Everton Freitas de Morais, Larissa Santos Amaral Rolim, Dennys Ramon de Melo Fernandes Almeida, Hannah Gil de Farias Morais, Lélia Batista de Souza, Roseana de Almeida Freitas
Fri Sep 11, 2020 16:30
Publication date: Available online 11 September 2020Source: Radiotherapy and OncologyAuthor(s): Chrissa Sioka, Andreas Fotopoulos
Fri Sep 11, 2020 16:30
Publication date: Available online 11 September 2020Source: Radiotherapy and OncologyAuthor(s): Huakang Huang, John Roberson, Wei Hou, Kartik Mani, Edward Valentine, Samuel Ryu, Alexander Stessin
Fri Sep 11, 2020 16:30
Publication date: Available online 11 September 2020Source: Radiotherapy and OncologyAuthor(s): Detlef Bartkowiak, Reinhard Thamm, Alessandra Siegmann, Dirk Böhmer, Volker Budachb, Thomas Wiegel
Fri Sep 11, 2020 16:30
Abstract Background Orthodontically-induced root resorption is an iatrogenic effect and it cannot be examined regularly due to the harmful effects of sequential doses of radiation with more frequent radiography. This study aims to compare protein abundance (PA) of pre-treatment and during orthodontic treatment for root resorption and to determine potential early markers for root resorption. ...
Fri Sep 11, 2020 03:00
Abstract Next-generation sequencing (NGS) is an incredibly useful tool for genetic disease diagnosis. However, the most commonly used bioinformatics methods for analyzing sequence reads insufficiently discriminate genomic regions with extensive sequence identity, such as gene families and pseudogenes, complicating diagnostics. This problem has been recognized for specific genes, including many involved in human disease, and diagnostic labs must perform additional costly steps...
Fri Sep 11, 2020 03:00
Publication date: Available online 11 September 2020Source: Behavioural Brain ResearchAuthor(s): Liying Lin, Xin-Fu Zhou, Larisa Bobrovskaya
Fri Sep 11, 2020 16:16
Publication date: Available online 10 September 2020Source: Behavioural Brain ResearchAuthor(s): Maede Rezaie, Mohammad Nasehi, Salar Vaseghi, Khalil Alimohammadzadeh, Mohammad Islami Vaghar, Mohammad-Hossein Mohammadi-Mahdiabadi-Hasani, Mohammad-Reza Zarrindast
Fri Sep 11, 2020 16:16
Abstract Purpose A circulating biomarker has potential to provide more accurate information for glioma progression post treatment, however no such biomarker is currently available. We aimed to discover a microRNA serum biomarker for longitudinal monitoring of glioma patients. Methods A prospectively collected cohort of 91 glioma patients and 17 healthy...
Fri Sep 11, 2020 03:00
As SARS-CoV-2 continues its global spread, it’s possible that one of the pillars of Covid-19 pandemic control — universal facial masking — might help reduce the severity of disease and ensure that a greater proportion of new infections are asymptomatic. If this hypothesis is borne out, universal…
Tue Sep 08, 2020 03:00
Oncogenesis, Published online: 11 September 2020; doi:10.1038/s41389-020-00265-zHypoxia induces an endometrial cancer stem-like cell phenotype via HIF-dependent demethylation of SOX2 mRNA
Fri Sep 11, 2020 03:00
Publication date: Available online 10 September 2020Source: The Journal of Prosthetic DentistryAuthor(s): João Pitta, Felix Burkhardt, Mustapha Mekki, Vincent Fehmer, Philippe Mojon, Irena Sailer
Fri Sep 11, 2020 15:53
Introduction: Tyrosine kinase inhibitors (TKIs) have been used in patients with advanced medullary thyroid carcinoma (MTC); however, data on their effectiveness and safety are limited. The aim of this systematic review and meta-analysis was to document clinical response and toxicities of TKIs in advanced MTC. Methods: We systematically searched major databases for articles or abstracts on TKI use in MTC patients until May 2018. Objective response (OR), defined as the sum of complete + partial response,...
Fri Sep 11, 2020 09:56
Publication date: Available online 11 September 2020Source: Journal of Plastic, Reconstructive & Aesthetic SurgeryAuthor(s): Horacio F. Mayer, Ignacio Piedra Buena, Maria Laura Petersen
Fri Sep 11, 2020 15:43
Publication date: Available online 11 September 2020Source: Journal of Plastic, Reconstructive & Aesthetic SurgeryAuthor(s): Sumarth K. Mehta, Olamide Olawoyin, Fouad Chouairi, Phan Q. Duy, Elbert J. Mets, Kyle S. Gabrick, Nicole K. Le, Tomer Avraham, Michael Alperovich
Fri Sep 11, 2020 15:43
Publication date: Available online 10 September 2020Source: Journal of Plastic, Reconstructive & Aesthetic SurgeryAuthor(s): Hope D. Shin, Abigail M. Rodriguez, Jasson T. Abraham, John C. Cargile, Candace N. Brown, Andrew M. Altman, Michel H. Saint-Cyr
Fri Sep 11, 2020 15:43
Publication date: Available online 10 September 2020Source: Journal of Plastic, Reconstructive & Aesthetic SurgeryAuthor(s): Nikolaos Lymperopoulos, Sami Ramadan, Ommen Koshy
Fri Sep 11, 2020 15:43
Publication date: Available online 10 September 2020Source: International Journal of Oral and Maxillofacial SurgeryAuthor(s): A.S. Lacagne, E. Brumpt, A. Barrabé, E. Pomero, B. Chatelain, F. Grillet, E. Weber, A. Malakhia, M. Pons, S. Aubry, C. Meyer, N. Sigaux, A. Louvrier
Fri Sep 11, 2020 15:44
Publication date: Available online 10 September 2020Source: International Journal of Oral and Maxillofacial SurgeryAuthor(s): O. Doganay, A. Houle, M.D. Han, M. Miloro
Fri Sep 11, 2020 15:44
Publication date: Available online 10 September 2020Source: International Journal of Oral and Maxillofacial SurgeryAuthor(s): F.C. Yogui, F.R. Verri, J.M. de Luna Gomes, C.A.A. Lemos, R.S. Cruz, E.P. Pellizzer
Fri Sep 11, 2020 15:44
Publication date: Available online 11 September 2020Source: Archives of Physical Medicine and RehabilitationAuthor(s): Sugalya Amatachaya, Donlaya Promkeaw, Preeda Arrayawichanon, Thiwabhorn Thaweewannakij, Pipatana Amatachaya
Fri Sep 11, 2020 15:39
Publication date: Available online 11 September 2020Source: Archives of Physical Medicine and RehabilitationAuthor(s): Yu-Ju Chang, Feng-Hang Chang, Peng-Hsuan Hou, Kai-Hsiang Tseng, Yen-Nung Lin
Fri Sep 11, 2020 15:39
Publication date: Available online 11 September 2020Source: Auris Nasus LarynxAuthor(s): Won Ki Cho, Woo Seok Kang, Jung Bok Lee, Hong Ju Park, Jong Woo Chung, Joong Ho Ahn
Fri Sep 11, 2020 15:39
Background Acute loss of smell and taste are well‐recognized symptoms of coronavirus disease 2019 (COVID‐19), yet the correlation between self‐reported and psychophysical olfactory function remains unclear. Understanding the reliability of self‐reported smell loss in ambulatory cases can assess the utility of this screening measure. Methods A prospective, longitudinal study evaluating patient‐reported and measured olfactory function using the validated 12‐item Brief Smell Identification Test...
Thu Sep 10, 2020 20:14
Thu Sep 10, 2020 20:13
Publication date: Available online 11 September 2020Source: Pathology - Research and PracticeAuthor(s): Sherry Lee, Yevgen Chornenkyy, Michael T. Swete, Samuel S. Kim, Ankit Bharat, Ximing J. Yang, Anjana Yeldandi
Fri Sep 11, 2020 15:21
Abstract Treatment stratification in stage IV NSCLC is guided by identification of oncogene driver mutations. Actionable mutations with current licenced therapeutic agents include epidermal growth factor receptor (EGFR), rearrangements of anaplastic lymphoma kinase (ALK), ROS-1 and BRAF V600. Alongside progress with small molecule therapy, developments in immune checkpoint inhibitors (CPIs) have transformed the landscape of stage III and stage IV NSCLC. The success of CPIs has...
Fri Sep 11, 2020 03:00
BACKGROUND Primary effusion lymphoma (PEL) is a very rare non‐Hodgkin lymphoma caused by human herpesvirus‐8 (HHV8) that grows in liquid phase within body cavities. The diagnosis of PEL is based on cytology but requires confirmatory ancillary tests. PEL occurs mainly in association with HIV infection. This study describes 9 cases of PEL in HIV‐negative patients and compares their characteristics with 10 HIV‐associated cases of PEL diagnosed at a single institution in Italy between 1995 and 2019....
Thu Sep 10, 2020 12:25
Publication date: Available online 10 September 2020Source: Sleep MedicineAuthor(s): Tao Liang, Heather M. Munro, Margaret K. Hargreaves, Mark D. Steinwandel, William J. Blot, Maciej S. Buchowski
Fri Sep 11, 2020 14:37
Publication date: Available online 10 September 2020Source: Sleep MedicineAuthor(s): Antonio Culebras
Fri Sep 11, 2020 14:37
Publication date: Available online 10 September 2020Source: Sleep MedicineAuthor(s): Tri Pham, Chung-Kuang Lin, Dustin Leek, Ravindra Chandrashekhar, Thiru Annaswamy
Fri Sep 11, 2020 14:37
Publication date: Available online 10 September 2020Source: Sleep MedicineAuthor(s): Philipp Ellmerer, Ambra Stefani, Beatrice Heim, Melanie Bergmann, Klaus Seppi, Werner Poewe, Birgit Högl, Atbin Djamshidian
Fri Sep 11, 2020 14:37
New Findings What is the central question of this study? Does Dnmt3a plays a critical role in regulating diabetic muscle atrophy? What is the main finding and its importance? Muscle atrophy is one of the major long‐term complications of diabetes mellitus. However, little is known about the molecular mechanism involved. In this paper, we demonstrated that Dnmt3a overexpression effectively improves the diabetic muscle health in mice and documented the underlying mechanisms. Dnmt3a...
Thu Sep 10, 2020 21:24
New Findings What is the topic of this review? This manuscript provides a review of the current understanding of the role of the sympathetic nervous system in regulation of the bone marrow‐derived immune cells and their involvement in hypertension. What advances does it highlight? We highlight the recent advances in understanding of the neuro‐immune interactions both peripherally and centrally as they relate to blood pressure control. Abstract The sympathetic nervous system...
Thu Sep 10, 2020 21:23
Δεν υπάρχουν σχόλια:
Δημοσίευση σχολίου
Σημείωση: Μόνο ένα μέλος αυτού του ιστολογίου μπορεί να αναρτήσει σχόλιο.