The role of innate immune signaling in the pathogenesis of atopic dermatitis and consequences for treatments
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 13 δευτερόλεπτα
The role of innate immune signaling in the pathogenesis of atopic dermatitis and consequences for treatments: AbstractThe skin is the largest organ at the interface between the environment and the host. Consequently, the skin plays a central role in mounting effective host defense. In addition to pathogens, the microbiota and the host immune system are in permanent contact and communication via the skin. Consequences of this permanent interaction are a unique and partly symbiotic relationship, a tight interdependence between these partners, and also a functional “setting the clock,... περισσότερα »
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 13 δευτερόλεπτα
The role of innate immune signaling in the pathogenesis of atopic dermatitis and consequences for treatments: AbstractThe skin is the largest organ at the interface between the environment and the host. Consequently, the skin plays a central role in mounting effective host defense. In addition to pathogens, the microbiota and the host immune system are in permanent contact and communication via the skin. Consequences of this permanent interaction are a unique and partly symbiotic relationship, a tight interdependence between these partners, and also a functional “setting the clock,... περισσότερα »
sec-Butylpropylacetamide (SPD) has antimigraine properties.
Alexandros G. SfakianakisστοHead and NeckΠριν από 13 δευτερόλεπτα
sec-Butylpropylacetamide (SPD) has antimigraine properties.: *sec-Butylpropylacetamide (SPD) has antimigraine properties.* Cephalalgia. 2015 Nov 13; Authors: Kaufmann D, Bates EA, Yagen B, Bialer M, Saunders GH, Wilcox K, White HS, Brennan KC Abstract BACKGROUND: Though migraine is disabling and affects 12%-15% of the population, there are few drugs that have been developed specifically for migraine prevention. Valproic acid (VPA) is a broad-spectrum antiepileptic drug (AED) that is also used for migraine prophylaxis, but its clinical use is limited by its side effect profile. se... περισσότερα »
Alexandros G. SfakianakisστοHead and NeckΠριν από 13 δευτερόλεπτα
sec-Butylpropylacetamide (SPD) has antimigraine properties.: *sec-Butylpropylacetamide (SPD) has antimigraine properties.* Cephalalgia. 2015 Nov 13; Authors: Kaufmann D, Bates EA, Yagen B, Bialer M, Saunders GH, Wilcox K, White HS, Brennan KC Abstract BACKGROUND: Though migraine is disabling and affects 12%-15% of the population, there are few drugs that have been developed specifically for migraine prevention. Valproic acid (VPA) is a broad-spectrum antiepileptic drug (AED) that is also used for migraine prophylaxis, but its clinical use is limited by its side effect profile. se... περισσότερα »
Can Peripheral Bronchopleural Fistula Demonstrated on Computed Tomography be Treated Conservatively? A Retrospective Analysis.
Alexandros G. SfakianakisστοHead and NeckΠριν από 14 δευτερόλεπτα
Can Peripheral Bronchopleural Fistula Demonstrated on Computed Tomography be Treated Conservatively? A Retrospective Analysis.: *Can Peripheral Bronchopleural Fistula Demonstrated on Computed Tomography be Treated Conservatively? A Retrospective Analysis.* J Comput Assist Tomogr. 2015 Nov 13; Authors: Tsubakimoto M, Murayama S, Iraha R, Kamiya H, Tsuchiya N, Yamashiro T Abstract PURPOSE: Peripheral bronchopleural fistulas (BPF) are communications between a peripheral bronchus or the lung parenchyma and the pleural space. Although reported cases with peripheral BPF might have typi... περισσότερα »
Alexandros G. SfakianakisστοHead and NeckΠριν από 14 δευτερόλεπτα
Can Peripheral Bronchopleural Fistula Demonstrated on Computed Tomography be Treated Conservatively? A Retrospective Analysis.: *Can Peripheral Bronchopleural Fistula Demonstrated on Computed Tomography be Treated Conservatively? A Retrospective Analysis.* J Comput Assist Tomogr. 2015 Nov 13; Authors: Tsubakimoto M, Murayama S, Iraha R, Kamiya H, Tsuchiya N, Yamashiro T Abstract PURPOSE: Peripheral bronchopleural fistulas (BPF) are communications between a peripheral bronchus or the lung parenchyma and the pleural space. Although reported cases with peripheral BPF might have typi... περισσότερα »
Do Left- and Right-Handed People Have Similar Iron Deposition in the Basal Ganglia?
Alexandros G. SfakianakisστοHead and NeckΠριν από 14 δευτερόλεπτα
Do Left- and Right-Handed People Have Similar Iron Deposition in the Basal Ganglia?: *Do Left- and Right-Handed People Have Similar Iron Deposition in the Basal Ganglia?* J Comput Assist Tomogr. 2015 Nov 13; Authors: Wang D, Li YH, Wang H Abstract OBJECTIVES: This study aimed to investigate whether right-, left-, or mixed-handed people differ in terms of iron deposition using susceptibility weighted imaging in healthy subjects. MATERIALS AND METHODS: A total of 87 people (right-handed, 51 subjects; left-handed, 19 subjects; mixed-handed, 17 subjects) aged 20 to 40 years partici... περισσότερα »
Alexandros G. SfakianakisστοHead and NeckΠριν από 14 δευτερόλεπτα
Do Left- and Right-Handed People Have Similar Iron Deposition in the Basal Ganglia?: *Do Left- and Right-Handed People Have Similar Iron Deposition in the Basal Ganglia?* J Comput Assist Tomogr. 2015 Nov 13; Authors: Wang D, Li YH, Wang H Abstract OBJECTIVES: This study aimed to investigate whether right-, left-, or mixed-handed people differ in terms of iron deposition using susceptibility weighted imaging in healthy subjects. MATERIALS AND METHODS: A total of 87 people (right-handed, 51 subjects; left-handed, 19 subjects; mixed-handed, 17 subjects) aged 20 to 40 years partici... περισσότερα »
Optimal Contrast of Cerebral Duel-Energy Computed Tomography Angiography in Patients With Spontaneous Subarachnoid Hemorrhage.
Alexandros G. SfakianakisστοHead and NeckΠριν από 14 δευτερόλεπτα
Optimal Contrast of Cerebral Duel-Energy Computed Tomography Angiography in Patients With Spontaneous Subarachnoid Hemorrhage.: *Optimal Contrast of Cerebral Duel-Energy Computed Tomography Angiography in Patients With Spontaneous Subarachnoid Hemorrhage.* J Comput Assist Tomogr. 2015 Nov 13; Authors: Wang D, Zhang Q, Hu H, Zhang W, Chen R, Zee CS, Yu R Abstract OBJECTIVE: The aim of this study was to investigate the image quality of cerebral dual-energy computed tomography (CT) angiography using a nonlinear image blending technique as compared with the conventional linear blendin... περισσότερα »
Alexandros G. SfakianakisστοHead and NeckΠριν από 14 δευτερόλεπτα
Optimal Contrast of Cerebral Duel-Energy Computed Tomography Angiography in Patients With Spontaneous Subarachnoid Hemorrhage.: *Optimal Contrast of Cerebral Duel-Energy Computed Tomography Angiography in Patients With Spontaneous Subarachnoid Hemorrhage.* J Comput Assist Tomogr. 2015 Nov 13; Authors: Wang D, Zhang Q, Hu H, Zhang W, Chen R, Zee CS, Yu R Abstract OBJECTIVE: The aim of this study was to investigate the image quality of cerebral dual-energy computed tomography (CT) angiography using a nonlinear image blending technique as compared with the conventional linear blendin... περισσότερα »
Dural Thickening of the Internal Auditory Canal in Patients With Spontaneous Intracranial Hypotension Syndrome.
Alexandros G. SfakianakisστοHead and NeckΠριν από 14 δευτερόλεπτα
Dural Thickening of the Internal Auditory Canal in Patients With Spontaneous Intracranial Hypotension Syndrome.: *Dural Thickening of the Internal Auditory Canal in Patients With Spontaneous Intracranial Hypotension Syndrome.* J Comput Assist Tomogr. 2015 Nov 13; Authors: Hori S, Taoka T, Miyasaka T, Ochi T, Sakamoto M, Wada T, Myochin K, Takayama K, Kichikawa K Abstract OBJECTIVE: This study aimed to assess the utility of dural thickening of the internal auditory canal (IAC) in patients with spontaneous intracranial hypotension (SIH) syndrome and determined the sensitivity and s...περισσότερα »
Alexandros G. SfakianakisστοHead and NeckΠριν από 14 δευτερόλεπτα
Dural Thickening of the Internal Auditory Canal in Patients With Spontaneous Intracranial Hypotension Syndrome.: *Dural Thickening of the Internal Auditory Canal in Patients With Spontaneous Intracranial Hypotension Syndrome.* J Comput Assist Tomogr. 2015 Nov 13; Authors: Hori S, Taoka T, Miyasaka T, Ochi T, Sakamoto M, Wada T, Myochin K, Takayama K, Kichikawa K Abstract OBJECTIVE: This study aimed to assess the utility of dural thickening of the internal auditory canal (IAC) in patients with spontaneous intracranial hypotension (SIH) syndrome and determined the sensitivity and s...περισσότερα »
Persistent Asymmetric Brain MIBG Activity Related to a Cerebrovascular Infarct.
Alexandros G. SfakianakisστοHead and NeckΠριν από 14 δευτερόλεπτα
Persistent Asymmetric Brain MIBG Activity Related to a Cerebrovascular Infarct.: *Persistent Asymmetric Brain MIBG Activity Related to a Cerebrovascular Infarct.* Clin Nucl Med. 2015 Nov 13; Authors: Bai X, Zhuang H Abstract A 13-year-old woman with a history of left malignant carotid body paraganglioma status postsurgical resection underwent I-MIBG scan for staging. The images demonstrated no definite evidence of MIBG-avid disease. However, there was asymmetric activity in the region of the brain with relatively less activity on the left compared with the contralateral right s... περισσότερα »
Alexandros G. SfakianakisστοHead and NeckΠριν από 14 δευτερόλεπτα
Persistent Asymmetric Brain MIBG Activity Related to a Cerebrovascular Infarct.: *Persistent Asymmetric Brain MIBG Activity Related to a Cerebrovascular Infarct.* Clin Nucl Med. 2015 Nov 13; Authors: Bai X, Zhuang H Abstract A 13-year-old woman with a history of left malignant carotid body paraganglioma status postsurgical resection underwent I-MIBG scan for staging. The images demonstrated no definite evidence of MIBG-avid disease. However, there was asymmetric activity in the region of the brain with relatively less activity on the left compared with the contralateral right s... περισσότερα »
Bone Scintigraphic Findings in MRSA Osteomyelitis.
Alexandros G. SfakianakisστοHead and NeckΠριν από 14 δευτερόλεπτα
Bone Scintigraphic Findings in MRSA Osteomyelitis.: *Bone Scintigraphic Findings in MRSA Osteomyelitis.* Clin Nucl Med. 2015 Nov 13; Authors: Cornejo P, Mandell GA Abstract Methicillin-resistant Staphylococcus aureus osteomyelitis is a severe form of infection characterized by multifocal or multiple segmental osseous involvement and subperiosteal abscess formation with increased frequency of extraosseous complications including pyomyositis, septic thrombus, and septic arthritis. Bone scan showed long segment and/or multifocal involvement in 4 of 5 patients with areas of abnormal ...περισσότερα »
Alexandros G. SfakianakisστοHead and NeckΠριν από 14 δευτερόλεπτα
Bone Scintigraphic Findings in MRSA Osteomyelitis.: *Bone Scintigraphic Findings in MRSA Osteomyelitis.* Clin Nucl Med. 2015 Nov 13; Authors: Cornejo P, Mandell GA Abstract Methicillin-resistant Staphylococcus aureus osteomyelitis is a severe form of infection characterized by multifocal or multiple segmental osseous involvement and subperiosteal abscess formation with increased frequency of extraosseous complications including pyomyositis, septic thrombus, and septic arthritis. Bone scan showed long segment and/or multifocal involvement in 4 of 5 patients with areas of abnormal ...περισσότερα »
18F-FDG PET/CT Findings in Multicentric Reticulohistiocytosis.
Alexandros G. SfakianakisστοHead and NeckΠριν από 14 δευτερόλεπτα
18F-FDG PET/CT Findings in Multicentric Reticulohistiocytosis.: *18F-FDG PET/CT Findings in Multicentric Reticulohistiocytosis.* Clin Nucl Med. 2015 Nov 13; Authors: Zhang B, Zhou H, Han J, Shi X, Zhang X Abstract Multicentric reticulohistiocytosis is a rare systemic inflammatory disease of unknown etiology characterized by the infiltration of histiocytes and multinucleated giant cells into multiple systems. The definitive diagnosis depends on biopsy of the affected tissues. Here, we report the F-FDG PET/CT findings of a 62-year-old man with multicentric reticulohistiocytosis. In...περισσότερα »
Alexandros G. SfakianakisστοHead and NeckΠριν από 14 δευτερόλεπτα
18F-FDG PET/CT Findings in Multicentric Reticulohistiocytosis.: *18F-FDG PET/CT Findings in Multicentric Reticulohistiocytosis.* Clin Nucl Med. 2015 Nov 13; Authors: Zhang B, Zhou H, Han J, Shi X, Zhang X Abstract Multicentric reticulohistiocytosis is a rare systemic inflammatory disease of unknown etiology characterized by the infiltration of histiocytes and multinucleated giant cells into multiple systems. The definitive diagnosis depends on biopsy of the affected tissues. Here, we report the F-FDG PET/CT findings of a 62-year-old man with multicentric reticulohistiocytosis. In...περισσότερα »
Reconstruction of a Post Traumatic Anterior Maxillary Defect by Transport Distraction Osteogenesis
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 15 δευτερόλεπτα
Reconstruction of a Post Traumatic Anterior Maxillary Defect by Transport Distraction Osteogenesis Abstract Rehabilitation of segmental defects of maxilla presents a reconstructive challenge to obtain an ideal osseous form and height with adequate soft tissue investment. Though variety of prosthetic and surgical reconstructive options like the use of vascularized and non vascularized bone grafts are available they produce less than optimal results. Bone transport distraction is a reliable procedure in various maxillofacial bony defect reconstruction techniques. We describe herein ... περισσότερα »
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 15 δευτερόλεπτα
Reconstruction of a Post Traumatic Anterior Maxillary Defect by Transport Distraction Osteogenesis Abstract Rehabilitation of segmental defects of maxilla presents a reconstructive challenge to obtain an ideal osseous form and height with adequate soft tissue investment. Though variety of prosthetic and surgical reconstructive options like the use of vascularized and non vascularized bone grafts are available they produce less than optimal results. Bone transport distraction is a reliable procedure in various maxillofacial bony defect reconstruction techniques. We describe herein ... περισσότερα »
Incidence of Retrocochlear Pathology Found on MRI in Patients With Non-Pulsatile Tinnitus
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 18 δευτερόλεπτα
Incidence of Retrocochlear Pathology Found on MRI in Patients With Non-Pulsatile Tinnitus Choi, Kevin J.; Sajisevi, Mirabelle B.; Kahmke, Russel R.; Kaylie, David M. [image: Collapse Box]Abstract Objective: To identify the incidence of retrocochlear pathology on MRI in patients with non-pulsatile tinnitus. Study Design: Retrospective review. Setting: Tertiary referral center. Patients: Adults with MRIs performed between March 1, 2008 and February 1, 2014 for non-pulsatile tinnitus with or without hearing loss. Intervention: MRI. Main Outcome Measure: Incidence of retrocochlear pathol... περισσότερα »
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 18 δευτερόλεπτα
Incidence of Retrocochlear Pathology Found on MRI in Patients With Non-Pulsatile Tinnitus Choi, Kevin J.; Sajisevi, Mirabelle B.; Kahmke, Russel R.; Kaylie, David M. [image: Collapse Box]Abstract Objective: To identify the incidence of retrocochlear pathology on MRI in patients with non-pulsatile tinnitus. Study Design: Retrospective review. Setting: Tertiary referral center. Patients: Adults with MRIs performed between March 1, 2008 and February 1, 2014 for non-pulsatile tinnitus with or without hearing loss. Intervention: MRI. Main Outcome Measure: Incidence of retrocochlear pathol... περισσότερα »
Management of Geniculate Ganglion Hemangiomas: Case Series and Systematic Review of the Literature
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 18 δευτερόλεπτα
Management of Geniculate Ganglion Hemangiomas: Case Series and Systematic Review of the Literature Oldenburg, Michael S.*; Carlson, Matthew L.*; Van Abel, Kathryn M.*; Driscoll, Colin L.*,†; Link, Michael J.*,† [image: Collapse Box]Abstract Objective: To analyze facial nerve (FN) outcomes based on duration of FN palsy and surgical strategy in patients with geniculate ganglion hemangiomas (GGH). Study Design: Case series and systematic review of the literature. Setting: Tertiary care center. Subjects and Methods: All patients undergoing surgical resection of GGH from 1992 to 2014 we... περισσότερα »
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 18 δευτερόλεπτα
Management of Geniculate Ganglion Hemangiomas: Case Series and Systematic Review of the Literature Oldenburg, Michael S.*; Carlson, Matthew L.*; Van Abel, Kathryn M.*; Driscoll, Colin L.*,†; Link, Michael J.*,† [image: Collapse Box]Abstract Objective: To analyze facial nerve (FN) outcomes based on duration of FN palsy and surgical strategy in patients with geniculate ganglion hemangiomas (GGH). Study Design: Case series and systematic review of the literature. Setting: Tertiary care center. Subjects and Methods: All patients undergoing surgical resection of GGH from 1992 to 2014 we... περισσότερα »
Dexamethasone Protects Against Radiation-induced Loss of Auditory Hair Cells In Vitro
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 18 δευτερόλεπτα
Dexamethasone Protects Against Radiation-induced Loss of Auditory Hair Cells In Vitro Dinh, Christine*; Chen, Si*; Padgett, Kyle†; Dinh, John*; Telischi, Fred*; Elsayyad, Nagy†; Johnson, Perry†; Angeli, Simon*; Bas, Esperanza*; Goncalves, Stefania*; Eshraghi, Adrien*; Van De Water, Thomas* [image: Collapse Box]Abstract Hypothesis: Dexamethasone (DXM) protects against radiation-induced loss of auditory hair cells (HCs) in rat organ of Corti (OC) explants by reducing levels of oxidative stress and apoptosis. Background: Radiation-induced sensorineural hearing loss (HL) is progressiv... περισσότερα »
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 18 δευτερόλεπτα
Dexamethasone Protects Against Radiation-induced Loss of Auditory Hair Cells In Vitro Dinh, Christine*; Chen, Si*; Padgett, Kyle†; Dinh, John*; Telischi, Fred*; Elsayyad, Nagy†; Johnson, Perry†; Angeli, Simon*; Bas, Esperanza*; Goncalves, Stefania*; Eshraghi, Adrien*; Van De Water, Thomas* [image: Collapse Box]Abstract Hypothesis: Dexamethasone (DXM) protects against radiation-induced loss of auditory hair cells (HCs) in rat organ of Corti (OC) explants by reducing levels of oxidative stress and apoptosis. Background: Radiation-induced sensorineural hearing loss (HL) is progressiv... περισσότερα »
Eustachian Tube Mucosal Inflammation Scale Validation Based on Digital Video Images
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 19 δευτερόλεπτα
Eustachian Tube Mucosal Inflammation Scale Validation Based on Digital Video Images: Conclusion: The inflammation scale used for Eustachian tube mucosal inflammation is reliable and this scale can be used with a high level of consistency by clinicians with various levels of experience. (Source: Otology and Neurotology) Kivekäs, Ilkka*,†; Pöyhönen, Leena*; Aarnisalo, Antti‡; Rautiainen, Markus*; Poe, Dennis† [image: Collapse Box]Abstract Background: The most common cause for Eustachian tube dilatory dysfunction is mucosal inflammation. The aim of this study was to validate a scale f... περισσότερα »
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 19 δευτερόλεπτα
Eustachian Tube Mucosal Inflammation Scale Validation Based on Digital Video Images: Conclusion: The inflammation scale used for Eustachian tube mucosal inflammation is reliable and this scale can be used with a high level of consistency by clinicians with various levels of experience. (Source: Otology and Neurotology) Kivekäs, Ilkka*,†; Pöyhönen, Leena*; Aarnisalo, Antti‡; Rautiainen, Markus*; Poe, Dennis† [image: Collapse Box]Abstract Background: The most common cause for Eustachian tube dilatory dysfunction is mucosal inflammation. The aim of this study was to validate a scale f... περισσότερα »
Electro-Mechanical Stimulation of the Cochlea by Vibrating Cochlear Implant Electrodes
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 20 δευτερόλεπτα
Electro-Mechanical Stimulation of the Cochlea by Vibrating Cochlear Implant Electrodes: Conclusion: The feasibility of cochlear stimulation by vibrating electrodes was shown although the achieved output level at frequencies ≤1 kHz was too low for EAS applications. (Source: Otology and Neurotology) Mueller, Mathias; Salcher, Rolf; Majdani, Omid; Lenarz, Thomas; Maier, Hannes [image: Collapse Box]Abstract Introduction: Electro-acoustic stimulation (EAS) of the cochlea uses the preserved residual low-frequency hearing for acoustic stimulation in combination with electrical stimulati... περισσότερα »
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 20 δευτερόλεπτα
Electro-Mechanical Stimulation of the Cochlea by Vibrating Cochlear Implant Electrodes: Conclusion: The feasibility of cochlear stimulation by vibrating electrodes was shown although the achieved output level at frequencies ≤1 kHz was too low for EAS applications. (Source: Otology and Neurotology) Mueller, Mathias; Salcher, Rolf; Majdani, Omid; Lenarz, Thomas; Maier, Hannes [image: Collapse Box]Abstract Introduction: Electro-acoustic stimulation (EAS) of the cochlea uses the preserved residual low-frequency hearing for acoustic stimulation in combination with electrical stimulati... περισσότερα »
Bilateral Changes of Spontaneous Activity Within the Central Auditory Pathway Upon Chronic Unilateral Intracochlear Electrical Stimulation
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 20 δευτερόλεπτα
Bilateral Changes of Spontaneous Activity Within the Central Auditory Pathway Upon Chronic Unilateral Intracochlear Electrical Stimulation: Conclusions: Unilateral intracochlear electrical stimulation seems to facilitate the homeostasis of the network activity, since it decreases the spontaneous activity that is usually elevated upon deafferentiation. The electrical stimulation per se seems to be responsible for the bilateral changes described above, rather than the particular nature of the electrical stimulation (e.g., rate). The normalization effects of electrical stimulation foun... περισσότερα »
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 20 δευτερόλεπτα
Bilateral Changes of Spontaneous Activity Within the Central Auditory Pathway Upon Chronic Unilateral Intracochlear Electrical Stimulation: Conclusions: Unilateral intracochlear electrical stimulation seems to facilitate the homeostasis of the network activity, since it decreases the spontaneous activity that is usually elevated upon deafferentiation. The electrical stimulation per se seems to be responsible for the bilateral changes described above, rather than the particular nature of the electrical stimulation (e.g., rate). The normalization effects of electrical stimulation foun... περισσότερα »
Methicillin-Resistant Staphylococcus aureus Otic Capsule and Pontine Infection Masquerading as an Internal Auditory Canal Neoplasm
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 21 δευτερόλεπτα
Methicillin-Resistant Staphylococcus aureus Otic Capsule and Pontine Infection Masquerading as an Internal Auditory Canal Neoplasm
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 21 δευτερόλεπτα
Methicillin-Resistant Staphylococcus aureus Otic Capsule and Pontine Infection Masquerading as an Internal Auditory Canal Neoplasm
HASTE Diffusion-Weighted Magnetic Resonance Imaging of Middle Ear Teratoma
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 21 δευτερόλεπτα
HASTE Diffusion-Weighted Magnetic Resonance Imaging of Middle Ear Teratoma
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 21 δευτερόλεπτα
HASTE Diffusion-Weighted Magnetic Resonance Imaging of Middle Ear Teratoma
The Medially Migrating Intracanalicular Vestibular Schwannoma
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 22 δευτερόλεπτα
The Medially Migrating Intracanalicular Vestibular Schwannoma:
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 22 δευτερόλεπτα
The Medially Migrating Intracanalicular Vestibular Schwannoma:
Anatomy of smell
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 23 δευτερόλεπτα
Microanatomy - Epithelium - glands - mucosa - Sustentacular cell Olfactory nerve: 1° neuron - Olfactory receptor neurons (Olfactory receptor) → Olfactory bulb ( Glomeruli) Olfactory nerve: 2° neuron - Mitral cells → Olfactory tract → Olfactory trigone Lateral olfactory stria/ Primary olfactory cortex - Piriform cortex - EC-hippocampus system - Entorhinal cortex - Hippocampal formation - Prepyriform area - Periamygdaloid cortex - Stria medullaris → Habenular nuclei - Amygdala → Stria terminalis → Hypothalamus - Media... περισσότερα »
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 23 δευτερόλεπτα
Microanatomy - Epithelium - glands - mucosa - Sustentacular cell Olfactory nerve: 1° neuron - Olfactory receptor neurons (Olfactory receptor) → Olfactory bulb ( Glomeruli) Olfactory nerve: 2° neuron - Mitral cells → Olfactory tract → Olfactory trigone Lateral olfactory stria/ Primary olfactory cortex - Piriform cortex - EC-hippocampus system - Entorhinal cortex - Hippocampal formation - Prepyriform area - Periamygdaloid cortex - Stria medullaris → Habenular nuclei - Amygdala → Stria terminalis → Hypothalamus - Media... περισσότερα »
The medial orbital gyrus presents a well-marked antero-posterior sulcus, the olfactory sulcus, for the olfactory tract.
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 23 δευτερόλεπτα
Olfactory sulcus From Wikipedia, the free encyclopedia *Olfactory sulcus*[image: Gray729 olfactory sulcus.png] Orbital surface of left frontal lobe. (Olfactory sulcus visible at upper left.) [image: Gray743.png] Coronal section through anterior cornua of lateral ventricles. (Sulcus olfactorius labeled at bottom center.) DetailsLatin*sulcus olfactorius lobi frontalis*IdentifiersGray'sp.822 NeuroNames*hier-60*NeuroLexID*Olfactory sulcus*Dorlands /Elsevier*s_28/12769409*TAA14.1.09.219FMA83769Anatomical terms of neuroanatomy The medial orbital gyrus presents a well-marked antero-posterior s... περισσότερα »
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 23 δευτερόλεπτα
Olfactory sulcus From Wikipedia, the free encyclopedia *Olfactory sulcus*[image: Gray729 olfactory sulcus.png] Orbital surface of left frontal lobe. (Olfactory sulcus visible at upper left.) [image: Gray743.png] Coronal section through anterior cornua of lateral ventricles. (Sulcus olfactorius labeled at bottom center.) DetailsLatin*sulcus olfactorius lobi frontalis*IdentifiersGray'sp.822 NeuroNames*hier-60*NeuroLexID*Olfactory sulcus*Dorlands /Elsevier*s_28/12769409*TAA14.1.09.219FMA83769Anatomical terms of neuroanatomy The medial orbital gyrus presents a well-marked antero-posterior s... περισσότερα »
High-Frequency Repetitive Transcranial Magnetic Stimulation Reduces Pain in Postherpetic Neuralgia
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 23 δευτερόλεπτα
High-Frequency Repetitive Transcranial Magnetic Stimulation Reduces Pain in Postherpetic Neuralgia: Abstract Objectives Postherpetic neuralgia (PHN) is one of the most intractable pain disorders, especially in elderly patients. There is evidence that repetitive transcranial magnetic stimulation (rTMS) reduces neuropathic pain; however, its effectiveness for PHN is unknown. This study investigated the efficacy of high-frequency rTMS in patients with PHN. Design A total of 40 patients were randomly assigned to receive 10 sessions of real or sham rTMS of the primary motor cortex. Each ... περισσότερα »
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 23 δευτερόλεπτα
High-Frequency Repetitive Transcranial Magnetic Stimulation Reduces Pain in Postherpetic Neuralgia: Abstract Objectives Postherpetic neuralgia (PHN) is one of the most intractable pain disorders, especially in elderly patients. There is evidence that repetitive transcranial magnetic stimulation (rTMS) reduces neuropathic pain; however, its effectiveness for PHN is unknown. This study investigated the efficacy of high-frequency rTMS in patients with PHN. Design A total of 40 patients were randomly assigned to receive 10 sessions of real or sham rTMS of the primary motor cortex. Each ... περισσότερα »
Magnetic Resonance Imaging Findings in Kallmann Syndrome
Alexandros G. SfakianakisστοHead and NeckΠριν από 27 δευτερόλεπτα
Magnetic Resonance Imaging Findings in Kallmann Syndrome: 14 Cases and Review of the Literature.: *Magnetic Resonance Imaging Findings in Kallmann Syndrome: 14 Cases and Review of the Literature.* J Comput Assist Tomogr. 2015 Nov 13; Authors: Zhang Z, Sun X, Wang C, Wang G, Zhao B Abstract PURPOSE: We sought to characterize the magnetic resonance imaging (MRI) findings in patients with Kallmann syndrome (KS). MATERIALS AND METHODS: Fourteen patients with KS and a comparison group of 20 matched people with normal MRI were analyzed with optimized voxel-based morphometry. Coronal T... περισσότερα »
Alexandros G. SfakianakisστοHead and NeckΠριν από 27 δευτερόλεπτα
Magnetic Resonance Imaging Findings in Kallmann Syndrome: 14 Cases and Review of the Literature.: *Magnetic Resonance Imaging Findings in Kallmann Syndrome: 14 Cases and Review of the Literature.* J Comput Assist Tomogr. 2015 Nov 13; Authors: Zhang Z, Sun X, Wang C, Wang G, Zhao B Abstract PURPOSE: We sought to characterize the magnetic resonance imaging (MRI) findings in patients with Kallmann syndrome (KS). MATERIALS AND METHODS: Fourteen patients with KS and a comparison group of 20 matched people with normal MRI were analyzed with optimized voxel-based morphometry. Coronal T... περισσότερα »
Precise Localization of Occult Gastrointestinal Hemorrhage Using Dynamic SPECT/CT.
Alexandros G. SfakianakisστοHead and NeckΠριν από 27 δευτερόλεπτα
Precise Localization of Occult Gastrointestinal Hemorrhage Using Dynamic SPECT/CT.: *Precise Localization of Occult Gastrointestinal Hemorrhage Using Dynamic SPECT/CT.* Clin Nucl Med. 2015 Nov 13; Authors: Murrey DA, Hall NC, Wright CL, Mankoff DA Abstract Active but intermittent gastrointestinal (GI) bleeding can be readily detected with dynamic planar scintigraphic imaging. This is a case of a 48-year-old woman who presented from an outside institution with active GI bleeding on Tc-labeled RBC (Tc-RBC) scintigraphy, but the upper and lower GI evaluations failed to subsequently...περισσότερα »
Alexandros G. SfakianakisστοHead and NeckΠριν από 27 δευτερόλεπτα
Precise Localization of Occult Gastrointestinal Hemorrhage Using Dynamic SPECT/CT.: *Precise Localization of Occult Gastrointestinal Hemorrhage Using Dynamic SPECT/CT.* Clin Nucl Med. 2015 Nov 13; Authors: Murrey DA, Hall NC, Wright CL, Mankoff DA Abstract Active but intermittent gastrointestinal (GI) bleeding can be readily detected with dynamic planar scintigraphic imaging. This is a case of a 48-year-old woman who presented from an outside institution with active GI bleeding on Tc-labeled RBC (Tc-RBC) scintigraphy, but the upper and lower GI evaluations failed to subsequently...περισσότερα »
Alterations in peripheral and central components of the auditory brainstem response: a neural assay of tinnitus.
Alexandros G. SfakianakisστοHead and NeckΠριν από 29 δευτερόλεπτα
Alterations in peripheral and central components of the auditory brainstem response: a neural assay of tinnitus.: [image: http:--www.plosone.org-images-pone_120x3] [image: http:--www.ncbi.nlm.nih.gov-corehtml-pmc] Related Articles*Alterations in peripheral and central components of the auditory brainstem response: a neural assay of tinnitus.* PLoS One. 2015;10(2):e0117228 Authors: Lowe AS, Walton JP Abstract Chronic tinnitus, or "ringing of the ears", affects upwards of 15% of the adult population. Identifying a cost-effective and objective measure of tinnitus is needed due to l... περισσότερα »
Alexandros G. SfakianakisστοHead and NeckΠριν από 29 δευτερόλεπτα
Alterations in peripheral and central components of the auditory brainstem response: a neural assay of tinnitus.: [image: http:--www.plosone.org-images-pone_120x3] [image: http:--www.ncbi.nlm.nih.gov-corehtml-pmc] Related Articles*Alterations in peripheral and central components of the auditory brainstem response: a neural assay of tinnitus.* PLoS One. 2015;10(2):e0117228 Authors: Lowe AS, Walton JP Abstract Chronic tinnitus, or "ringing of the ears", affects upwards of 15% of the adult population. Identifying a cost-effective and objective measure of tinnitus is needed due to l... περισσότερα »
[Potential of adipose-derived stem cells concerning the treatment of wound healing complications after radiotherapy].
Alexandros G. SfakianakisστοHead and NeckΠριν από 29 δευτερόλεπτα
[Potential of adipose-derived stem cells concerning the treatment of wound healing complications after radiotherapy].: [image: http:--production.springer.de-OnlineReso] Related Articles*[Potential of adipose-derived stem cells concerning the treatment of wound healing complications after radiotherapy].* HNO. 2015 Feb;63(2):111-7 Authors: Haubner F, Gassner HG Abstract BACKGROUND: Compromised wound healing in irradiated tissues is a common and challenging clinical problem. The pathophysiology and underlying cellular mechanisms including the complex interaction of cytokines and gro... περισσότερα »
Alexandros G. SfakianakisστοHead and NeckΠριν από 29 δευτερόλεπτα
[Potential of adipose-derived stem cells concerning the treatment of wound healing complications after radiotherapy].: [image: http:--production.springer.de-OnlineReso] Related Articles*[Potential of adipose-derived stem cells concerning the treatment of wound healing complications after radiotherapy].* HNO. 2015 Feb;63(2):111-7 Authors: Haubner F, Gassner HG Abstract BACKGROUND: Compromised wound healing in irradiated tissues is a common and challenging clinical problem. The pathophysiology and underlying cellular mechanisms including the complex interaction of cytokines and gro... περισσότερα »
Mast Cells in Asthma
Alexandros G. SfakianakisστοHead and NeckΠριν από 30 δευτερόλεπτα
Mast Cells in Asthma - State of the Art.: *Mast Cells in Asthma - State of the Art.* Clin Exp Allergy. 2015 Nov 14; Authors: Bradding P, Arthur G Abstract Mast cells (MCs) play a central role in tissue homeostasis, sensing the local environment through numerous innate cell surface receptors. This enables them to respond rapidly to perceived tissue insults with a view to initiating a co-ordinated program of inflammation and repair. However, when the tissue insult is chronic, the ongoing release of multiple pro-inflammatory mediators, proteases, cytokines and chemokines leads to t... περισσότερα »
Alexandros G. SfakianakisστοHead and NeckΠριν από 30 δευτερόλεπτα
Mast Cells in Asthma - State of the Art.: *Mast Cells in Asthma - State of the Art.* Clin Exp Allergy. 2015 Nov 14; Authors: Bradding P, Arthur G Abstract Mast cells (MCs) play a central role in tissue homeostasis, sensing the local environment through numerous innate cell surface receptors. This enables them to respond rapidly to perceived tissue insults with a view to initiating a co-ordinated program of inflammation and repair. However, when the tissue insult is chronic, the ongoing release of multiple pro-inflammatory mediators, proteases, cytokines and chemokines leads to t... περισσότερα »
Occupational exposures and chronic kidney disease: Possible associations with endotoxin and ultrafine particles
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 30 δευτερόλεπτα
Occupational exposures and chronic kidney disease: Possible associations with endotoxin and ultrafine particles: Background Chronic kidney disease (CKD) carries a high public health burden yet there is limited research on occupational factors, which are examined in this retrospective case-control study. Methods Newly diagnosed cases of CKD (n = 547) and controls (n = 508) from North Carolina provided detailed work histories in telephone interviews. Unconditional logistic regression was used to estimate odds ratios (ORs) and 95% confidence intervals (CIs). Results There was heterogen...περισσότερα »
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 30 δευτερόλεπτα
Occupational exposures and chronic kidney disease: Possible associations with endotoxin and ultrafine particles: Background Chronic kidney disease (CKD) carries a high public health burden yet there is limited research on occupational factors, which are examined in this retrospective case-control study. Methods Newly diagnosed cases of CKD (n = 547) and controls (n = 508) from North Carolina provided detailed work histories in telephone interviews. Unconditional logistic regression was used to estimate odds ratios (ORs) and 95% confidence intervals (CIs). Results There was heterogen...περισσότερα »
Estimation of population iodine intake from iodized salt consumed through bouillon seasoning in Senegal
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 30 δευτερόλεπτα
Estimation of population iodine intake from iodized salt consumed through bouillon seasoning in Senegal: Universal salt iodization (USI) is the main global strategy to eliminate iodine deficiency. Regulation of USI programs often omits salt used in processed foods, despite their increasing contribution to salt intake. In West Africa, bouillon seasoning is a widely consumed source of salt and is therefore relevant to USI effectiveness. To develop program guidance around iodine in bouillon, iodine retention in 13 bouillon brands commercially available in Senegal was measured over 6 m... περισσότερα »
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 30 δευτερόλεπτα
Estimation of population iodine intake from iodized salt consumed through bouillon seasoning in Senegal: Universal salt iodization (USI) is the main global strategy to eliminate iodine deficiency. Regulation of USI programs often omits salt used in processed foods, despite their increasing contribution to salt intake. In West Africa, bouillon seasoning is a widely consumed source of salt and is therefore relevant to USI effectiveness. To develop program guidance around iodine in bouillon, iodine retention in 13 bouillon brands commercially available in Senegal was measured over 6 m... περισσότερα »
The steroid receptor RNA activator protein (SRAP) controls cancer cell migration/motility
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 30 δευτερόλεπτα
The steroid receptor RNA activator protein (SRAP) controls cancer cell migration/motility via ScienceDirect Publication: FEBS Letters Publication date: Available online 17 November 2015 *Source:*FEBS Letters Author(s): Yi Yan, Charlton Cooper, Mohammad K. Hamedani, Brent Guppy, Wayne Xu, Deborah Tsuyuki, Christine Zhang, Zoann Nugent, Anne Blanchard, James R. Davie, Kirk McManus, Leigh C. Murphy, Yvonne Myal, Etienne Leygue The steroid receptor RNA activator gene (SRA1) produces both a functional RNA (SRA) and a protein (SRAP), whose exact physiological roles remain unknown. To identif... περισσότερα »
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 30 δευτερόλεπτα
The steroid receptor RNA activator protein (SRAP) controls cancer cell migration/motility via ScienceDirect Publication: FEBS Letters Publication date: Available online 17 November 2015 *Source:*FEBS Letters Author(s): Yi Yan, Charlton Cooper, Mohammad K. Hamedani, Brent Guppy, Wayne Xu, Deborah Tsuyuki, Christine Zhang, Zoann Nugent, Anne Blanchard, James R. Davie, Kirk McManus, Leigh C. Murphy, Yvonne Myal, Etienne Leygue The steroid receptor RNA activator gene (SRA1) produces both a functional RNA (SRA) and a protein (SRAP), whose exact physiological roles remain unknown. To identif... περισσότερα »
Deep vein thrombosis prophylaxis
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 30 δευτερόλεπτα
in a tertiary care center: An observational study via ScienceDirect Publication: Apollo Medicine Publication date: Available online 20 October 2015 *Source:*Apollo Medicine Author(s): Aparna Yerramilli, Shilpa Katta, Supriya Kidambi, Naveen Kumar Kotari, Santosh Devulapally, Sanjeev Sharma BackgroundDeep vein thrombosis (DVT) is a major health problem with substantial mortality and morbidity in medically ill patients. Prevention of DVT by risk factor stratification and subsequent antithrombotic prophylaxis in moderate- to severe-risk category patients is the most rational means of red... περισσότερα »
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 30 δευτερόλεπτα
in a tertiary care center: An observational study via ScienceDirect Publication: Apollo Medicine Publication date: Available online 20 October 2015 *Source:*Apollo Medicine Author(s): Aparna Yerramilli, Shilpa Katta, Supriya Kidambi, Naveen Kumar Kotari, Santosh Devulapally, Sanjeev Sharma BackgroundDeep vein thrombosis (DVT) is a major health problem with substantial mortality and morbidity in medically ill patients. Prevention of DVT by risk factor stratification and subsequent antithrombotic prophylaxis in moderate- to severe-risk category patients is the most rational means of red... περισσότερα »
"Cold" Spondylodiscitis on 18F-FDG PET/CT in a Patient With Myelofibrosis.
Alexandros G. SfakianakisστοHead and NeckΠριν από 31 δευτερόλεπτα
"Cold" Spondylodiscitis on 18F-FDG PET/CT in a Patient With Myelofibrosis.: *"Cold" Spondylodiscitis on 18F-FDG PET/CT in a Patient With Myelofibrosis.* Clin Nucl Med. 2015 Nov 13; Authors: Rousseau E, Keu KV Abstract A 74-year-old man was evaluated by bone scan for possible rib fractures, which revealed a diffuse skeletal uptake secondary to myelofibrosis and focal midthoracic uptake. Chest CT and F-FDG PET/CT demonstrated pathological vertebral fractures of the midthoracic spine, which appeared as a cold defect on PET comparing to intense marrow uptake related to myelofibrosis ...περισσότερα »
Alexandros G. SfakianakisστοHead and NeckΠριν από 31 δευτερόλεπτα
"Cold" Spondylodiscitis on 18F-FDG PET/CT in a Patient With Myelofibrosis.: *"Cold" Spondylodiscitis on 18F-FDG PET/CT in a Patient With Myelofibrosis.* Clin Nucl Med. 2015 Nov 13; Authors: Rousseau E, Keu KV Abstract A 74-year-old man was evaluated by bone scan for possible rib fractures, which revealed a diffuse skeletal uptake secondary to myelofibrosis and focal midthoracic uptake. Chest CT and F-FDG PET/CT demonstrated pathological vertebral fractures of the midthoracic spine, which appeared as a cold defect on PET comparing to intense marrow uptake related to myelofibrosis ...περισσότερα »
The effect of arm positioning on timing and enhancement of intravenous contrast media at coronary computed tomography angiography.
Alexandros G. SfakianakisστοHead and NeckΠριν από 31 δευτερόλεπτα
The effect of arm positioning on timing and enhancement of intravenous contrast media at coronary computed tomography angiography.: *The effect of arm positioning on timing and enhancement of intravenous contrast media at coronary computed tomography angiography.* Acta Radiol. 2015 Nov 13; Authors: Svensson A, Cederlund K, Aspelin P, Nyman U, Brismar TB Abstract BACKGROUND: Adequate intravenous contrast media (CM) enhancement is crucial for evaluation of the coronary arteries. PURPOSE: To compare the timing and enhancement of intravenous CM at coronary computed tomography angiogr... περισσότερα »
Alexandros G. SfakianakisστοHead and NeckΠριν από 31 δευτερόλεπτα
The effect of arm positioning on timing and enhancement of intravenous contrast media at coronary computed tomography angiography.: *The effect of arm positioning on timing and enhancement of intravenous contrast media at coronary computed tomography angiography.* Acta Radiol. 2015 Nov 13; Authors: Svensson A, Cederlund K, Aspelin P, Nyman U, Brismar TB Abstract BACKGROUND: Adequate intravenous contrast media (CM) enhancement is crucial for evaluation of the coronary arteries. PURPOSE: To compare the timing and enhancement of intravenous CM at coronary computed tomography angiogr... περισσότερα »
Anthracofibrosis Manifesting as False-Positive Iodine Accumulation in a Patient With Recent History of Thyroid Carcinoma.
Alexandros G. SfakianakisστοHead and NeckΠριν από 32 δευτερόλεπτα
Anthracofibrosis Manifesting as False-Positive Iodine Accumulation in a Patient With Recent History of Thyroid Carcinoma.: *Anthracofibrosis Manifesting as False-Positive Iodine Accumulation in a Patient With Recent History of Thyroid Carcinoma.* Clin Nucl Med. 2015 Nov 13; Authors: Licht K, Kroegel C, Katenkamp K, Freesmeyer M Abstract A 33-year-old Indonesian woman presented for follow-up after a recent history of papillary thyroid carcinoma treated with total thyroidectomy and radioiodine therapy. A I whole-body scintigraphy showed an elongated iodine accumulation in the right...περισσότερα »
Alexandros G. SfakianakisστοHead and NeckΠριν από 32 δευτερόλεπτα
Anthracofibrosis Manifesting as False-Positive Iodine Accumulation in a Patient With Recent History of Thyroid Carcinoma.: *Anthracofibrosis Manifesting as False-Positive Iodine Accumulation in a Patient With Recent History of Thyroid Carcinoma.* Clin Nucl Med. 2015 Nov 13; Authors: Licht K, Kroegel C, Katenkamp K, Freesmeyer M Abstract A 33-year-old Indonesian woman presented for follow-up after a recent history of papillary thyroid carcinoma treated with total thyroidectomy and radioiodine therapy. A I whole-body scintigraphy showed an elongated iodine accumulation in the right...περισσότερα »
Diffuse sclerosing variant of papillary thyroid carcinoma:Major genetic alterations and prognostic implications.
Alexandros G. SfakianakisστοHead and NeckΠριν από 32 δευτερόλεπτα
Diffuse sclerosing variant of papillary thyroid carcinoma:Major genetic alterations and prognostic implications.: *Diffuse sclerosing variant of papillary thyroid carcinoma:Major genetic alterations and prognostic implications.* Histopathology. 2015 Nov 14; Authors: Joung JY, Kim TH, Jeong DJ, Park SM, Cho YY, Jang HW, Jung YY, Oh YL, Yim HS, Kim YL, Chung JH, Ki CS, Kim SW Abstract AIM: Diffuse sclerosing variant of papillary thyroid carcinoma (DSV-PTC) is an uncommon variant of PTC, and its prognostic significance remains controversial. The aim of this study was to investigate ... περισσότερα »
Alexandros G. SfakianakisστοHead and NeckΠριν από 32 δευτερόλεπτα
Diffuse sclerosing variant of papillary thyroid carcinoma:Major genetic alterations and prognostic implications.: *Diffuse sclerosing variant of papillary thyroid carcinoma:Major genetic alterations and prognostic implications.* Histopathology. 2015 Nov 14; Authors: Joung JY, Kim TH, Jeong DJ, Park SM, Cho YY, Jang HW, Jung YY, Oh YL, Yim HS, Kim YL, Chung JH, Ki CS, Kim SW Abstract AIM: Diffuse sclerosing variant of papillary thyroid carcinoma (DSV-PTC) is an uncommon variant of PTC, and its prognostic significance remains controversial. The aim of this study was to investigate ... περισσότερα »
Fluorescence-guided surgery for cancer
Alexandros G. SfakianakisστοHead and NeckΠριν από 33 δευτερόλεπτα
Current status and future perspectives of fluorescence-guided surgery for cancer.: *Current status and future perspectives of fluorescence-guided surgery for cancer.* Expert Rev Anticancer Ther. 2015 Nov 15; Authors: DeLong J, Hoffman RM, Bouvet M Abstract Curative cancer surgery is dependent on the removal of all tumor and metastatic cancer cells. Preoperative imaging, intraoperative inspection and palpation, and pathological margin confirmation aid the surgeon, but these methods are lacking in sensitivity and can be highly subjective. Techniques in fluorescence-guided surgery ... περισσότερα »
Alexandros G. SfakianakisστοHead and NeckΠριν από 33 δευτερόλεπτα
Current status and future perspectives of fluorescence-guided surgery for cancer.: *Current status and future perspectives of fluorescence-guided surgery for cancer.* Expert Rev Anticancer Ther. 2015 Nov 15; Authors: DeLong J, Hoffman RM, Bouvet M Abstract Curative cancer surgery is dependent on the removal of all tumor and metastatic cancer cells. Preoperative imaging, intraoperative inspection and palpation, and pathological margin confirmation aid the surgeon, but these methods are lacking in sensitivity and can be highly subjective. Techniques in fluorescence-guided surgery ... περισσότερα »
The management of head and neck tumors with high technology radiation therapy.
Alexandros G. SfakianakisστοHead and NeckΠριν από 33 δευτερόλεπτα
The management of head and neck tumors with high technology radiation therapy.: *The management of head and neck tumors with high technology radiation therapy.* Expert Rev Anticancer Ther. 2015 Nov 15; Authors: Mendez LC, Moraes FY, Poon I, Marta GN Abstract Squamous cell carcinoma (SCC) is responsible for 90% of the head and neck cancers affecting over 600 thousand people worldwide. Radiation therapy, surgery and chemotherapy are the most important treatment modalities in head and neck SCC. The aim of this review is to summarize the recent innovations in head and neck radiation... περισσότερα »
Alexandros G. SfakianakisστοHead and NeckΠριν από 33 δευτερόλεπτα
The management of head and neck tumors with high technology radiation therapy.: *The management of head and neck tumors with high technology radiation therapy.* Expert Rev Anticancer Ther. 2015 Nov 15; Authors: Mendez LC, Moraes FY, Poon I, Marta GN Abstract Squamous cell carcinoma (SCC) is responsible for 90% of the head and neck cancers affecting over 600 thousand people worldwide. Radiation therapy, surgery and chemotherapy are the most important treatment modalities in head and neck SCC. The aim of this review is to summarize the recent innovations in head and neck radiation... περισσότερα »
Endoscopic surgery for malignant sinonasal tumours: an eighteen year experience.
Alexandros G. SfakianakisστοHead and NeckΠριν από 33 δευτερόλεπτα
Endoscopic surgery for malignant sinonasal tumours: an eighteen year experience.: Related Articles*Endoscopic surgery for malignant sinonasal tumours: an eighteen year experience.* Rhinology. 2015 Sep;53(3):204-11 Authors: Lund VJ, Wei WI Abstract INTRODUCTION: Curative resection of malignant tumours of the skull base is increasingly undertaken endoscopically. Hitherto the diverse histology, rarity and long natural history have made it difficult to accrue statistically robust cohorts for comparison with conventional craniofacial resection. It is now possible to make such a compa...περισσότερα »
Alexandros G. SfakianakisστοHead and NeckΠριν από 33 δευτερόλεπτα
Endoscopic surgery for malignant sinonasal tumours: an eighteen year experience.: Related Articles*Endoscopic surgery for malignant sinonasal tumours: an eighteen year experience.* Rhinology. 2015 Sep;53(3):204-11 Authors: Lund VJ, Wei WI Abstract INTRODUCTION: Curative resection of malignant tumours of the skull base is increasingly undertaken endoscopically. Hitherto the diverse histology, rarity and long natural history have made it difficult to accrue statistically robust cohorts for comparison with conventional craniofacial resection. It is now possible to make such a compa...περισσότερα »
The impact of chronic rhinosinusitis on sleep-disordered breathing.
Alexandros G. SfakianakisστοHead and NeckΠριν από 33 δευτερόλεπτα
The impact of chronic rhinosinusitis on sleep-disordered breathing.: *The impact of chronic rhinosinusitis on sleep-disordered breathing.* Rhinology. 2015 Nov 15; Authors: Peñaranda A, Garcia E, Barragan AM, Rondon MA, Perez A, Rojas MX, Caraballo L, Dennis RJ Abstract BACKGROUND: Several studies have shown variations in the prevalence of allergic rhinitis (AR) around the world, and different potential predisposing factors. More studies are needed on risk factors, specifically in developing countries. This study explored the association of several factors and AR among urban resid... περισσότερα »
Alexandros G. SfakianakisστοHead and NeckΠριν από 33 δευτερόλεπτα
The impact of chronic rhinosinusitis on sleep-disordered breathing.: *The impact of chronic rhinosinusitis on sleep-disordered breathing.* Rhinology. 2015 Nov 15; Authors: Peñaranda A, Garcia E, Barragan AM, Rondon MA, Perez A, Rojas MX, Caraballo L, Dennis RJ Abstract BACKGROUND: Several studies have shown variations in the prevalence of allergic rhinitis (AR) around the world, and different potential predisposing factors. More studies are needed on risk factors, specifically in developing countries. This study explored the association of several factors and AR among urban resid... περισσότερα »
Identifying the most important outcomes for systematic reviews of interventions for rhinosinusitis in adults: working with Patients, Public and Practitioners.
Alexandros G. SfakianakisστοHead and NeckΠριν από 33 δευτερόλεπτα
Identifying the most important outcomes for systematic reviews of interventions for rhinosinusitis in adults: working with Patients, Public and Practitioners.: *Identifying the most important outcomes for systematic reviews of interventions for rhinosinusitis in adults: working with Patients, Public and Practitioners.* Rhinology. 2015 Nov 15; Authors: Hopkins C, Philpott C, Crowe S, Regan S, Degun A, Papachristou I, Schilder AG Abstract INTRODUCTION: Promoting the assessment of health interventions using outcomes that matter to patients and practitioners is a key principle of C... περισσότερα »
Alexandros G. SfakianakisστοHead and NeckΠριν από 33 δευτερόλεπτα
Identifying the most important outcomes for systematic reviews of interventions for rhinosinusitis in adults: working with Patients, Public and Practitioners.: *Identifying the most important outcomes for systematic reviews of interventions for rhinosinusitis in adults: working with Patients, Public and Practitioners.* Rhinology. 2015 Nov 15; Authors: Hopkins C, Philpott C, Crowe S, Regan S, Degun A, Papachristou I, Schilder AG Abstract INTRODUCTION: Promoting the assessment of health interventions using outcomes that matter to patients and practitioners is a key principle of C... περισσότερα »
Minimally Invasive Treatment for Hard Palate-Invading Maxillary Keratocystic Odontogenic Tumor.
Alexandros G. SfakianakisστοHead and NeckΠριν από 33 δευτερόλεπτα
Minimally Invasive Treatment for Hard Palate-Invading Maxillary Keratocystic Odontogenic Tumor.: *Minimally Invasive Treatment for Hard Palate-Invading Maxillary Keratocystic Odontogenic Tumor.* Tohoku J Exp Med. 2015;237(4):267-272 Authors: Nomura K, Arakawa K, Fujishima F, Yamazaki Y, Ozawa D, Nomura Y, Hidaka H, Yoshida N, Katori Y Abstract Keratocystic odontogenic tumor (KCOT) is one of the benign developmental odontogenic cystic lesions arising from impacted teeth. In comparison to other odontogenic cysts, such as radicular cysts and dentigerous cysts, KCOT is known to be m... περισσότερα »
Alexandros G. SfakianakisστοHead and NeckΠριν από 33 δευτερόλεπτα
Minimally Invasive Treatment for Hard Palate-Invading Maxillary Keratocystic Odontogenic Tumor.: *Minimally Invasive Treatment for Hard Palate-Invading Maxillary Keratocystic Odontogenic Tumor.* Tohoku J Exp Med. 2015;237(4):267-272 Authors: Nomura K, Arakawa K, Fujishima F, Yamazaki Y, Ozawa D, Nomura Y, Hidaka H, Yoshida N, Katori Y Abstract Keratocystic odontogenic tumor (KCOT) is one of the benign developmental odontogenic cystic lesions arising from impacted teeth. In comparison to other odontogenic cysts, such as radicular cysts and dentigerous cysts, KCOT is known to be m... περισσότερα »
Early Post Operative Enteral Versus Parenteral Feeding after Esophageal Cancer Surgery.
Alexandros G. SfakianakisστοHead and NeckΠριν από 33 δευτερόλεπτα
Early Post Operative Enteral Versus Parenteral Feeding after Esophageal Cancer Surgery.: *Early Post Operative Enteral Versus Parenteral Feeding after Esophageal Cancer Surgery.* Iran J Otorhinolaryngol. 2015 Sep;27(82):331-6 Authors: Rajabi Mashhadi MT, Bagheri R, Ghayour-Mobarhan M, Zilaee M, Rezaei R, Maddah G, Majidi MR, Bahadornia M Abstract INTRODUCTION: The incidence of malnutrition in hospitalized patients is reported to be high. In particular, patients with esophageal cancer are prone to malnutrition, due to preoperative digestive system dysfunctions and short-term non-...περισσότερα »
Alexandros G. SfakianakisστοHead and NeckΠριν από 33 δευτερόλεπτα
Early Post Operative Enteral Versus Parenteral Feeding after Esophageal Cancer Surgery.: *Early Post Operative Enteral Versus Parenteral Feeding after Esophageal Cancer Surgery.* Iran J Otorhinolaryngol. 2015 Sep;27(82):331-6 Authors: Rajabi Mashhadi MT, Bagheri R, Ghayour-Mobarhan M, Zilaee M, Rezaei R, Maddah G, Majidi MR, Bahadornia M Abstract INTRODUCTION: The incidence of malnutrition in hospitalized patients is reported to be high. In particular, patients with esophageal cancer are prone to malnutrition, due to preoperative digestive system dysfunctions and short-term non-...περισσότερα »
Impact of Intravenous Tranexamic Acid on Hemorrhage During Endoscopic Sinus Surgery.
Alexandros G. SfakianakisστοHead and NeckΠριν από 33 δευτερόλεπτα
Impact of Intravenous Tranexamic Acid on Hemorrhage During Endoscopic Sinus Surgery.: *Impact of Intravenous Tranexamic Acid on Hemorrhage During Endoscopic Sinus Surgery.* Iran J Otorhinolaryngol. 2015 Sep;27(82):349-54 Authors: Nuhi S, Goljanian Tabrizi A, Zarkhah L, Rashedi Ashrafi B Abstract INTRODUCTION: Endoscopic sinus surgery is a common procedure performed by otolaryngologists. This study evaluated the efficacy of intravenous (IV) tranexamic acid (TA) on hemorrhage in patients undergoing elective endoscopic sinus surgery (ESS). MATERIALS AND METHODS: The present study w... περισσότερα »
Alexandros G. SfakianakisστοHead and NeckΠριν από 33 δευτερόλεπτα
Impact of Intravenous Tranexamic Acid on Hemorrhage During Endoscopic Sinus Surgery.: *Impact of Intravenous Tranexamic Acid on Hemorrhage During Endoscopic Sinus Surgery.* Iran J Otorhinolaryngol. 2015 Sep;27(82):349-54 Authors: Nuhi S, Goljanian Tabrizi A, Zarkhah L, Rashedi Ashrafi B Abstract INTRODUCTION: Endoscopic sinus surgery is a common procedure performed by otolaryngologists. This study evaluated the efficacy of intravenous (IV) tranexamic acid (TA) on hemorrhage in patients undergoing elective endoscopic sinus surgery (ESS). MATERIALS AND METHODS: The present study w... περισσότερα »
Why Cats Taste No Sweets
Alexandros G. SfakianakisστοΓεύση και ΌσφρησηΠριν από 33 δευτερόλεπτα
[image: 09C44080-D981-4780-887D12F0D781FF2B_arti] An old gene mutation is at fault -- Read more on ScientificAmerican.com [image: the-senses?d=yIl2AUoC8zA] [image: the-senses?d=qj6IDK7rITs] [image: the-senses?d=l6gmwiTKsz0] [image: the-senses?i=lgMs35-Y2-o:WAhlpPZQb0A:gIN] [image: the-senses?d=QXVau8BzmBE] [image: the-senses?d=I9og5sOYxJI] [image: the-senses?d=ZC7T4KBF6Nw] from #ΓεύσηΌσφρηση via ola Kala on Inoreader http://ift.tt/1YeQh5X via IFTTT
Alexandros G. SfakianakisστοΓεύση και ΌσφρησηΠριν από 33 δευτερόλεπτα
[image: 09C44080-D981-4780-887D12F0D781FF2B_arti] An old gene mutation is at fault -- Read more on ScientificAmerican.com [image: the-senses?d=yIl2AUoC8zA] [image: the-senses?d=qj6IDK7rITs] [image: the-senses?d=l6gmwiTKsz0] [image: the-senses?i=lgMs35-Y2-o:WAhlpPZQb0A:gIN] [image: the-senses?d=QXVau8BzmBE] [image: the-senses?d=I9og5sOYxJI] [image: the-senses?d=ZC7T4KBF6Nw] from #ΓεύσηΌσφρηση via ola Kala on Inoreader http://ift.tt/1YeQh5X via IFTTT
Limbic Encephalitis Diagnosed With 18F-FDG PET/CT
Alexandros G. SfakianakisστοHead and NeckΠριν από 40 δευτερόλεπτα
Limbic Encephalitis Diagnosed With 18F-FDG PET/CT. by Cózar Santiago MD, Sanchez Jurado R, Sanz Llorens R, Aguilar Barrios JE, Ferrer Rebolleda J via pubmed clin nucl med [jour... *Limbic Encephalitis Diagnosed With 18F-FDG PET/CT.* Clin Nucl Med. 2015 Nov 13; Authors: Cózar Santiago MD, Sanchez Jurado R, Sanz Llorens R, Aguilar Barrios JE, Ferrer Rebolleda J Abstract Limbic encephalitis is a subacute onset syndrome characterized by short-term memory impairment, confusion, temporal lobe epilepsy, hypothalamic dysfunction, and psychiatric symptoms. Common causes are autoimmune disorders... περισσότερα »
Alexandros G. SfakianakisστοHead and NeckΠριν από 40 δευτερόλεπτα
Limbic Encephalitis Diagnosed With 18F-FDG PET/CT. by Cózar Santiago MD, Sanchez Jurado R, Sanz Llorens R, Aguilar Barrios JE, Ferrer Rebolleda J via pubmed clin nucl med [jour... *Limbic Encephalitis Diagnosed With 18F-FDG PET/CT.* Clin Nucl Med. 2015 Nov 13; Authors: Cózar Santiago MD, Sanchez Jurado R, Sanz Llorens R, Aguilar Barrios JE, Ferrer Rebolleda J Abstract Limbic encephalitis is a subacute onset syndrome characterized by short-term memory impairment, confusion, temporal lobe epilepsy, hypothalamic dysfunction, and psychiatric symptoms. Common causes are autoimmune disorders... περισσότερα »
Bipartite hallucal sesamoid bone
Alexandros G. SfakianakisστοΠαθολοΑνατομίαΠριν από 44 δευτερόλεπτα
– A case report via ScienceDirect Publication: Apollo Medicine Publication date: Available online 23 October 2015 *Source:*Apollo Medicine Author(s): Vikram Khanna, Umamaheshwar Kodide, Nilesh Virani, Raju Vaishya A 34-year-old male patient came with complaints of a twisting injury to the left foot. There was a diffused swelling present in the left foot. The patient had tenderness at the base of the second metatarsal. On X-ray of the left foot, no obvious bony injury was seen, but there was a transverse split seen in the medial hallucal sesamoid bone. The patient was managed symptomat...περισσότερα »
Alexandros G. SfakianakisστοΠαθολοΑνατομίαΠριν από 44 δευτερόλεπτα
– A case report via ScienceDirect Publication: Apollo Medicine Publication date: Available online 23 October 2015 *Source:*Apollo Medicine Author(s): Vikram Khanna, Umamaheshwar Kodide, Nilesh Virani, Raju Vaishya A 34-year-old male patient came with complaints of a twisting injury to the left foot. There was a diffused swelling present in the left foot. The patient had tenderness at the base of the second metatarsal. On X-ray of the left foot, no obvious bony injury was seen, but there was a transverse split seen in the medial hallucal sesamoid bone. The patient was managed symptomat...περισσότερα »
Hyaluronic acid for anticancer drug and nucleic acid delivery
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 45 δευτερόλεπτα
Hyaluronic acid for anticancer drug and nucleic acid delivery via ScienceDirect Publication Advanced Drug Delivery Reviews Publication date: Available online 17 November 2015 *Source:*Advanced Drug Delivery Reviews Author(s): Franco Dosio, Silvia Arpicco, Barbara Stella, Elias Fattal Hyaluronic acid (HA) is widely used in anticancer drug delivery, since it is biocompatible, biodegradable, non-toxic, and non-immunogenic; moreover, HA receptors are overexpressed on many tumor cells. Exploiting this ligand-receptor interaction, the use of HA is now a rapidly-growing platform for targeting ... περισσότερα »
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 45 δευτερόλεπτα
Hyaluronic acid for anticancer drug and nucleic acid delivery via ScienceDirect Publication Advanced Drug Delivery Reviews Publication date: Available online 17 November 2015 *Source:*Advanced Drug Delivery Reviews Author(s): Franco Dosio, Silvia Arpicco, Barbara Stella, Elias Fattal Hyaluronic acid (HA) is widely used in anticancer drug delivery, since it is biocompatible, biodegradable, non-toxic, and non-immunogenic; moreover, HA receptors are overexpressed on many tumor cells. Exploiting this ligand-receptor interaction, the use of HA is now a rapidly-growing platform for targeting ... περισσότερα »
Cancer therapy targeting the fibrinolytic system
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 45 δευτερόλεπτα
Cancer therapy targeting the fibrinolytic system via ScienceDirect Publication Advanced Drug Delivery Reviews *Source:*Advanced Drug Delivery Reviews Author(s): Beate Heissig, Salita Eiamboonsert, Yousef Salama, Hiroshi Shimazu, Douaa Dhahri, Shinya Munakata, Yoshihiko Tashiro, Koichi Hattori The tumor microenvironment is recognized as a key factor in the multiple stages of cancer progression, mediating local resistance, immune-escape and metastasis. Cancer growth and progression require remodeling of the tumor stromal microenvironment, such as the development of tumor-associated blood... περισσότερα »
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 45 δευτερόλεπτα
Cancer therapy targeting the fibrinolytic system via ScienceDirect Publication Advanced Drug Delivery Reviews *Source:*Advanced Drug Delivery Reviews Author(s): Beate Heissig, Salita Eiamboonsert, Yousef Salama, Hiroshi Shimazu, Douaa Dhahri, Shinya Munakata, Yoshihiko Tashiro, Koichi Hattori The tumor microenvironment is recognized as a key factor in the multiple stages of cancer progression, mediating local resistance, immune-escape and metastasis. Cancer growth and progression require remodeling of the tumor stromal microenvironment, such as the development of tumor-associated blood... περισσότερα »
Anti-Reflux Laparoscopy Surgery
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 48 δευτερόλεπτα
Anti-Reflux Laparoscopy Surgery PreOp® Patient Education: Anti-Reflux Laparoscopy Surgery PreOp® Patient Education StoreMD™ for Physician videos: http://store.preop.com Patient Education Company Your doctor has recommended that you undergo surgery to treat reflux disease. But what does that actually mean? Your diaphragm is a muscle that separates your chest from your abdomen and helps you to breathe. Normally, the diaphragm has an opening for the esophagus to pass through where it connects with the stomach. At this point, the ring-like layer of muscle which acts as a one-wa...περισσότερα »
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 48 δευτερόλεπτα
Anti-Reflux Laparoscopy Surgery PreOp® Patient Education: Anti-Reflux Laparoscopy Surgery PreOp® Patient Education StoreMD™ for Physician videos: http://store.preop.com Patient Education Company Your doctor has recommended that you undergo surgery to treat reflux disease. But what does that actually mean? Your diaphragm is a muscle that separates your chest from your abdomen and helps you to breathe. Normally, the diaphragm has an opening for the esophagus to pass through where it connects with the stomach. At this point, the ring-like layer of muscle which acts as a one-wa...περισσότερα »
Persistent postural-perceptual dizziness (PPPD) is the most common vestibular disorder in the age group between 30 and 50 years
Alexandros G. SfakianakisστοΑκοή και ΙσορροπίαΠριν από 48 δευτερόλεπτα
Persistent Postural-Perceptual Dizziness: A Matter of Higher, Central Dysfunction?: by Dagny Holle, Benedict Schulte-Steinberg, Sebastian Wurthmann, Steffen Naegel, Ilya Ayzenberg, Hans-Christoph Diener, Zaza Katsarava, Mark Obermann Objective Persistent postural-perceptual dizziness (PPPD) is the most common vestibular disorder in the age group between 30 and 50 years. It is considered to be based on a multisensory maladjustment involving alterations of sensory response pattern including vestibular, visual and motion stimuli. Previous data supported a link between vestibular and...περισσότερα »
Alexandros G. SfakianakisστοΑκοή και ΙσορροπίαΠριν από 48 δευτερόλεπτα
Persistent Postural-Perceptual Dizziness: A Matter of Higher, Central Dysfunction?: by Dagny Holle, Benedict Schulte-Steinberg, Sebastian Wurthmann, Steffen Naegel, Ilya Ayzenberg, Hans-Christoph Diener, Zaza Katsarava, Mark Obermann Objective Persistent postural-perceptual dizziness (PPPD) is the most common vestibular disorder in the age group between 30 and 50 years. It is considered to be based on a multisensory maladjustment involving alterations of sensory response pattern including vestibular, visual and motion stimuli. Previous data supported a link between vestibular and...περισσότερα »
Can High-Resolution Computed Tomography Detect a Therapeutic Response to Medical Treatment in a Patient With Otosclerosis?.
Alexandros G. SfakianakisστοΑκοή και ΙσορροπίαΠριν από 48 δευτερόλεπτα
Can High-Resolution Computed Tomography Detect a Therapeutic Response to Medical Treatment in a Patient With Otosclerosis?
Alexandros G. SfakianakisστοΑκοή και ΙσορροπίαΠριν από 48 δευτερόλεπτα
Can High-Resolution Computed Tomography Detect a Therapeutic Response to Medical Treatment in a Patient With Otosclerosis?
Transcanal Endoscopic Management of Cerebrospinal Fluid Otorrhea Secondary to Congenital Inner Ear Malformations.
Alexandros G. SfakianakisστοΑκοή και ΙσορροπίαΠριν από 48 δευτερόλεπτα
Transcanal Endoscopic Management of Cerebrospinal Fluid Otorrhea Secondary to Congenital Inner Ear Malformations.: Objective: To describe the feasibility of using a transcanal endoscopic approach for management of cerebrospinal leaks secondary to congenital inner ear malformations. Patients: Two pediatric patients with congenital inner ear malformations and concurrent cerebrospinal fluid leakage. Intervention: A stapedectomy was performed and the inner ear was packed with temporalis muscle using a transcanal endoscopic approach. Main Outcome Measure: Cessation of cerebrospinal fluid le...περισσότερα »
Alexandros G. SfakianakisστοΑκοή και ΙσορροπίαΠριν από 48 δευτερόλεπτα
Transcanal Endoscopic Management of Cerebrospinal Fluid Otorrhea Secondary to Congenital Inner Ear Malformations.: Objective: To describe the feasibility of using a transcanal endoscopic approach for management of cerebrospinal leaks secondary to congenital inner ear malformations. Patients: Two pediatric patients with congenital inner ear malformations and concurrent cerebrospinal fluid leakage. Intervention: A stapedectomy was performed and the inner ear was packed with temporalis muscle using a transcanal endoscopic approach. Main Outcome Measure: Cessation of cerebrospinal fluid le...περισσότερα »
Early Bimodal Stimulation Benefits Language Acquisition for Children With Cochlear Implants.
Alexandros G. SfakianakisστοΑκοή και ΙσορροπίαΠριν από 48 δευτερόλεπτα
Early Bimodal Stimulation Benefits Language Acquisition for Children With Cochlear Implants.: Hypothesis: Adding a low-frequency acoustic signal to the cochlear implant (CI) signal (i.e., bimodal stimulation) for a period of time early in life improves language acquisition. Background: Children must acquire sensitivity to the phonemic units of language to develop most language-related skills, including expressive vocabulary, working memory, and reading. Acquiring sensitivity to phonemic structure depends largely on having refined spectral (frequency) representations available in the ... περισσότερα »
Alexandros G. SfakianakisστοΑκοή και ΙσορροπίαΠριν από 48 δευτερόλεπτα
Early Bimodal Stimulation Benefits Language Acquisition for Children With Cochlear Implants.: Hypothesis: Adding a low-frequency acoustic signal to the cochlear implant (CI) signal (i.e., bimodal stimulation) for a period of time early in life improves language acquisition. Background: Children must acquire sensitivity to the phonemic units of language to develop most language-related skills, including expressive vocabulary, working memory, and reading. Acquiring sensitivity to phonemic structure depends largely on having refined spectral (frequency) representations available in the ... περισσότερα »
Non-Human Primates Harbor Diverse Mammalian and Avian Astroviruses Including Those Associated with Human Infections
Alexandros G. SfakianakisστοΛοίμωξηΠριν από 50 δευτερόλεπτα
Non-Human Primates Harbor Diverse Mammalian and Avian Astroviruses Including Those Associated with Human Infections: [image: journal.ppat.1005225.t001] by Erik A Karlsson, Christopher T Small, Pamela Freiden, MM Feeroz, Frederick A Matsen, Sorn San, M Kamrul Hasan, David Wang, Lisa Jones-Engel, Stacey Schultz-Cherry Astroviruses (AstVs) are positive sense, single-stranded RNA viruses transmitted to a wide range of hosts via the fecal-oral route. The number of AstV-infected animal hosts has rapidly expanded in recent years with many more likely to be discovered because of the ad... περισσότερα »
Alexandros G. SfakianakisστοΛοίμωξηΠριν από 50 δευτερόλεπτα
Non-Human Primates Harbor Diverse Mammalian and Avian Astroviruses Including Those Associated with Human Infections: [image: journal.ppat.1005225.t001] by Erik A Karlsson, Christopher T Small, Pamela Freiden, MM Feeroz, Frederick A Matsen, Sorn San, M Kamrul Hasan, David Wang, Lisa Jones-Engel, Stacey Schultz-Cherry Astroviruses (AstVs) are positive sense, single-stranded RNA viruses transmitted to a wide range of hosts via the fecal-oral route. The number of AstV-infected animal hosts has rapidly expanded in recent years with many more likely to be discovered because of the ad... περισσότερα »
Enhancer Runaway and the Evolution of Diploid Gene Expression
Alexandros G. SfakianakisστοEvolutionary PhysiologyΠριν από 52 δευτερόλεπτα
Enhancer Runaway and the Evolution of Diploid Gene Expression: by Frédéric Fyon, Aurélie Cailleau, Thomas Lenormand Evidence is mounting that the evolution of gene expression plays a major role in adaptation and speciation. Understanding the evolution of gene regulatory regions is indeed an essential step in linking genotypes and phenotypes and in understanding the molecular mechanisms underlying evolutionary change. The common view is that expression traits (protein folding, expression timing, tissue localization and concentration) are under natural selection at the individual lev...περισσότερα »
Alexandros G. SfakianakisστοEvolutionary PhysiologyΠριν από 52 δευτερόλεπτα
Enhancer Runaway and the Evolution of Diploid Gene Expression: by Frédéric Fyon, Aurélie Cailleau, Thomas Lenormand Evidence is mounting that the evolution of gene expression plays a major role in adaptation and speciation. Understanding the evolution of gene regulatory regions is indeed an essential step in linking genotypes and phenotypes and in understanding the molecular mechanisms underlying evolutionary change. The common view is that expression traits (protein folding, expression timing, tissue localization and concentration) are under natural selection at the individual lev...περισσότερα »
Convergent Evolution During Local Adaptation to Patchy Landscapes
Alexandros G. SfakianakisστοEvolutionary PhysiologyΠριν από 53 δευτερόλεπτα
Convergent Evolution During Local Adaptation to Patchy Landscapes: [image: journal.pgen.1005630.e002.PNG] by Peter L. Ralph, Graham Coop Species often encounter, and adapt to, many patches of similar environmental conditions across their range. Such adaptation can occur through convergent evolution if different alleles arise in different patches, or through the spread of shared alleles by migration acting to synchronize adaptation across the species. The tension between the two reflects the constraint imposed on evolution by the underlying genetic architecture versus how effective... περισσότερα »
Alexandros G. SfakianakisστοEvolutionary PhysiologyΠριν από 53 δευτερόλεπτα
Convergent Evolution During Local Adaptation to Patchy Landscapes: [image: journal.pgen.1005630.e002.PNG] by Peter L. Ralph, Graham Coop Species often encounter, and adapt to, many patches of similar environmental conditions across their range. Such adaptation can occur through convergent evolution if different alleles arise in different patches, or through the spread of shared alleles by migration acting to synchronize adaptation across the species. The tension between the two reflects the constraint imposed on evolution by the underlying genetic architecture versus how effective... περισσότερα »
Teratoma of the Middle Ear With Cholesteatoma.
Alexandros G. SfakianakisστοΑκοή και ΙσορροπίαΠριν από 55 δευτερόλεπτα
Teratoma of the Middle Ear With Cholesteatoma
Alexandros G. SfakianakisστοΑκοή και ΙσορροπίαΠριν από 55 δευτερόλεπτα
Teratoma of the Middle Ear With Cholesteatoma
The effect of World Trade Center exposure on the latency of chronic rhinosinusitis diagnoses in New York City firefighters: 2001-2011
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 56 δευτερόλεπτα
The effect of World Trade Center exposure on the latency of chronic rhinosinusitis diagnoses in New York City firefighters: 2001-2011: Objective To assess how the effect of World Trade Center (WTC) exposure on physician-diagnosed chronic rhinosinusitis (CRS) in firefighters changed during the decade following the attack on 9/11 (11 September 2001 to 10 September 2011). Methods We examined temporal effects on the relation between WTC exposure and the incidence of physician diagnosed CRS in firefighters changed during the decade following the attack on 9/11 (11 September 2001 to 10 S... περισσότερα »
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 56 δευτερόλεπτα
The effect of World Trade Center exposure on the latency of chronic rhinosinusitis diagnoses in New York City firefighters: 2001-2011: Objective To assess how the effect of World Trade Center (WTC) exposure on physician-diagnosed chronic rhinosinusitis (CRS) in firefighters changed during the decade following the attack on 9/11 (11 September 2001 to 10 September 2011). Methods We examined temporal effects on the relation between WTC exposure and the incidence of physician diagnosed CRS in firefighters changed during the decade following the attack on 9/11 (11 September 2001 to 10 S... περισσότερα »
Resveratrol ameliorates Imiquimod-induced psoriasis-like skin inflammation
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 56 δευτερόλεπτα
GSE63684 Resveratrol ameliorates Imiquimod-induced psoriasis-like skin inflammation in mice: *Contributors* : Thomas N Kjær ; Steen B Pedersen *Series Type* : Expression profiling by array *Organism* : Mus musculus The polyphenol resveratrol has anti-inflammatory effects in various cells, tissues, animals and human settings of low-grade inflammation. Psoriasis is a disease of both localized and systemic low-grade inflammation. The Sirtuin1 enzyme thought to mediate the effects of resveratrol is present in skin and resveratrol is known to downregulate NF-κB; a major contributor in t...περισσότερα »
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 56 δευτερόλεπτα
GSE63684 Resveratrol ameliorates Imiquimod-induced psoriasis-like skin inflammation in mice: *Contributors* : Thomas N Kjær ; Steen B Pedersen *Series Type* : Expression profiling by array *Organism* : Mus musculus The polyphenol resveratrol has anti-inflammatory effects in various cells, tissues, animals and human settings of low-grade inflammation. Psoriasis is a disease of both localized and systemic low-grade inflammation. The Sirtuin1 enzyme thought to mediate the effects of resveratrol is present in skin and resveratrol is known to downregulate NF-κB; a major contributor in t...περισσότερα »
Differentiating between detrimental and beneficial interruptions: a mixed-methods study
Alexandros G. SfakianakisστοΝευρολογία κ' ΝευροχειρουργικήΠριν από 57 δευτερόλεπτα
Differentiating between detrimental and beneficial interruptions: a mixed-methods study: Introduction Efforts to understand interruptions now span much of the last decade and a half. Often thought to negatively impact patient safety, some now acknowledge that interruptions may be beneficial and actually necessary for safety and high quality care. This study seeks a framework for differentiating between interruptions that are detrimental and those that are beneficial. Methods A mixed-methods approach at a US Level 1 trauma centre included direct observation of 13 registered nurses ... περισσότερα »
Alexandros G. SfakianakisστοΝευρολογία κ' ΝευροχειρουργικήΠριν από 57 δευτερόλεπτα
Differentiating between detrimental and beneficial interruptions: a mixed-methods study: Introduction Efforts to understand interruptions now span much of the last decade and a half. Often thought to negatively impact patient safety, some now acknowledge that interruptions may be beneficial and actually necessary for safety and high quality care. This study seeks a framework for differentiating between interruptions that are detrimental and those that are beneficial. Methods A mixed-methods approach at a US Level 1 trauma centre included direct observation of 13 registered nurses ... περισσότερα »
A systematic review of stroke recognition instruments in hospital and prehospital settings
Alexandros G. SfakianakisστοΝευρολογία κ' ΝευροχειρουργικήΠριν από 57 δευτερόλεπτα
A systematic review of stroke recognition instruments in hospital and prehospital settings: Background We undertook a systematic review of all published stroke identification instruments to describe their performance characteristics when used prospectively in any clinical setting. Methods A search strategy was applied to Medline and Embase for material published prior to 10 August 2015. Two authors independently screened titles, and abstracts as necessary. Data including clinical setting, reported sensitivity, specificity, positive predictive value, negative predictive value were ... περισσότερα »
Alexandros G. SfakianakisστοΝευρολογία κ' ΝευροχειρουργικήΠριν από 57 δευτερόλεπτα
A systematic review of stroke recognition instruments in hospital and prehospital settings: Background We undertook a systematic review of all published stroke identification instruments to describe their performance characteristics when used prospectively in any clinical setting. Methods A search strategy was applied to Medline and Embase for material published prior to 10 August 2015. Two authors independently screened titles, and abstracts as necessary. Data including clinical setting, reported sensitivity, specificity, positive predictive value, negative predictive value were ... περισσότερα »
Pacemaker lead vegetation sited between the right atrium and the right ventricle
Alexandros G. SfakianakisστοΝευρολογία κ' ΝευροχειρουργικήΠριν από 57 δευτερόλεπτα
Pacemaker lead vegetation sited between the right atrium and the right ventricle: Case A 64-year-old man presented with a month's history of fatigue, general malaise and occasional rigours. He was feeling feverish on examination with no peripheral stigmata of infective endocarditis. The patient had a prior history of a permanent pacemaker (PPM) placed in 1980 for symptomatic bradycardia, with the most recent box change in 2011. There was also a history of atrial fibrillation and known moderate mitral regurgitation with an echocardiogram demonstrating an ejection fraction of 50%–55% ... περισσότερα »
Alexandros G. SfakianakisστοΝευρολογία κ' ΝευροχειρουργικήΠριν από 57 δευτερόλεπτα
Pacemaker lead vegetation sited between the right atrium and the right ventricle: Case A 64-year-old man presented with a month's history of fatigue, general malaise and occasional rigours. He was feeling feverish on examination with no peripheral stigmata of infective endocarditis. The patient had a prior history of a permanent pacemaker (PPM) placed in 1980 for symptomatic bradycardia, with the most recent box change in 2011. There was also a history of atrial fibrillation and known moderate mitral regurgitation with an echocardiogram demonstrating an ejection fraction of 50%–55% ... περισσότερα »
Q-ball imaging models: comparison between high and low angular resolution diffusion-weighted MRI protocols for investigation of brain white matter integrity
Alexandros G. SfakianakisστοΝευρολογία κ' ΝευροχειρουργικήΠριν από 57 δευτερόλεπτα
Q-ball imaging models: comparison between high and low angular resolution diffusion-weighted MRI protocols for investigation of brain white matter integrity: Abstract IntroductionQ-ball imaging (QBI) is one of the typical data models for quantifying white matter (WM) anisotropy in diffusion-weighted MRI (DwMRI) studies. Brain and spinal investigation by high angular resolution DwMRI (high angular resolution imaging (HARDI)) protocols exhibits higher angular resolution in diffusion imaging compared to low angular resolution models, although with longer acquisition times. We aimed t... περισσότερα »
Alexandros G. SfakianakisστοΝευρολογία κ' ΝευροχειρουργικήΠριν από 57 δευτερόλεπτα
Q-ball imaging models: comparison between high and low angular resolution diffusion-weighted MRI protocols for investigation of brain white matter integrity: Abstract IntroductionQ-ball imaging (QBI) is one of the typical data models for quantifying white matter (WM) anisotropy in diffusion-weighted MRI (DwMRI) studies. Brain and spinal investigation by high angular resolution DwMRI (high angular resolution imaging (HARDI)) protocols exhibits higher angular resolution in diffusion imaging compared to low angular resolution models, although with longer acquisition times. We aimed t... περισσότερα »
Anti-Coagulation and Deep Brain Stimulation: Never the Twain Shall Meet?
Alexandros G. SfakianakisστοΝευρολογία κ' ΝευροχειρουργικήΠριν από 57 δευτερόλεπτα
Anti-Coagulation and Deep Brain Stimulation: Never the Twain Shall Meet?: Deep brain stimulation (DBS) for movement disorders is usually performed in older patients who may be prone to vascular co-morbidities such as atrial fibrillation or valvular disease that may require anti-coagulation. This potentially increases the risk of peri-operative intra-cranial haemorrhage and thus anti-coagulation therapy is generally considered a contraindication for DBS implantation. Cessation of anti-coagulants has to be balanced with the risk of thrombosis or ischaemic complications and, to compoun...περισσότερα »
Alexandros G. SfakianakisστοΝευρολογία κ' ΝευροχειρουργικήΠριν από 57 δευτερόλεπτα
Anti-Coagulation and Deep Brain Stimulation: Never the Twain Shall Meet?: Deep brain stimulation (DBS) for movement disorders is usually performed in older patients who may be prone to vascular co-morbidities such as atrial fibrillation or valvular disease that may require anti-coagulation. This potentially increases the risk of peri-operative intra-cranial haemorrhage and thus anti-coagulation therapy is generally considered a contraindication for DBS implantation. Cessation of anti-coagulants has to be balanced with the risk of thrombosis or ischaemic complications and, to compoun...περισσότερα »
Pure versus combined Merkel cell carcinomas: immunohistochemical evaluation of cellular proteins (p53, Bcl-2, and c-kit) reveals significant overexpression of p53 in combined tumors.
Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
Hum Pathol. 2015 Sep;46(9):1290-6. doi: 10.1016/j.humpath.2015.05.008. Epub 2015 May 27. Lai JH1, Fleming KE2, Ly TY2, Pasternak S2, Godlewski M3, Doucette S4, Walsh NM5. Author information 1Department of Pathology, Queen Elizabeth II Health Sciences Center, Capital District Health Authority, Halifax, NS, B3H 1V8, Canada. 2Department of Pathology, Queen Elizabeth II Health Sciences Center, Capital District Health Authority, Halifax, NS, B3H 1V8, Canada; Dalhousie University, Halifax, NS, B3H 1V8, Canada. 3Dalhousie University, Halifax, NS, B3H 1V8, Canada; Department of Pathology, Sai... περισσότερα »
Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
Hum Pathol. 2015 Sep;46(9):1290-6. doi: 10.1016/j.humpath.2015.05.008. Epub 2015 May 27. Lai JH1, Fleming KE2, Ly TY2, Pasternak S2, Godlewski M3, Doucette S4, Walsh NM5. Author information 1Department of Pathology, Queen Elizabeth II Health Sciences Center, Capital District Health Authority, Halifax, NS, B3H 1V8, Canada. 2Department of Pathology, Queen Elizabeth II Health Sciences Center, Capital District Health Authority, Halifax, NS, B3H 1V8, Canada; Dalhousie University, Halifax, NS, B3H 1V8, Canada. 3Dalhousie University, Halifax, NS, B3H 1V8, Canada; Department of Pathology, Sai... περισσότερα »
Silencing of Kv1.5 Gene Inhibits Proliferation and Induces Apoptosis of Osteosarcoma Cells
Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
Int J Mol Sci. 2015 Nov 11;16(11):26914-26926. Wu J1, Chen Z2, Liu Q3, Zeng W4, Wu X5, Lin B6. Author information 1Department of Orthopaedics, the Affiliated Southeast Hospital of Xiamen University, Orthopaedic Center of People's Liberation Army, Zhangzhou 363000, China. wu215@iupui.edu. 2Department of Orthopaedics, the Affiliated Southeast Hospital of Xiamen University, Orthopaedic Center of People's Liberation Army, Zhangzhou 363000, China. chenzhida175th@gmail.com. 3Department of Orthopaedics, the Affiliated Southeast Hospital of Xiamen University, Orthopaedic Center of People's Lib... περισσότερα »
Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
Int J Mol Sci. 2015 Nov 11;16(11):26914-26926. Wu J1, Chen Z2, Liu Q3, Zeng W4, Wu X5, Lin B6. Author information 1Department of Orthopaedics, the Affiliated Southeast Hospital of Xiamen University, Orthopaedic Center of People's Liberation Army, Zhangzhou 363000, China. wu215@iupui.edu. 2Department of Orthopaedics, the Affiliated Southeast Hospital of Xiamen University, Orthopaedic Center of People's Liberation Army, Zhangzhou 363000, China. chenzhida175th@gmail.com. 3Department of Orthopaedics, the Affiliated Southeast Hospital of Xiamen University, Orthopaedic Center of People's Lib... περισσότερα »
Pineal parenchymal tumours of intermediate differentiation
Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
Br J Neurosurg. 2015 Nov 16:1-5. [Epub ahead of print] Pineal parenchymal tumours of intermediate differentiation - An evidence-based review of a new pathological entity. Amato-Watkins AC1, Lammie A2,3, Hayhurst C1, Leach P1. Author information 1a Department of Neurosurgery , University Hospital of Wales , Cardiff , UK. 2b Department of Neuropathology , University Hospital of Wales , Cardiff , UK. 3c Department of Pathology , University Hospital of Wales , Cardiff , UK. Abstract Pineal region lesions are uncommon, and pineal parenchymal tumours (PPT) account for 20-30% of tumours in this... περισσότερα »
Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
Br J Neurosurg. 2015 Nov 16:1-5. [Epub ahead of print] Pineal parenchymal tumours of intermediate differentiation - An evidence-based review of a new pathological entity. Amato-Watkins AC1, Lammie A2,3, Hayhurst C1, Leach P1. Author information 1a Department of Neurosurgery , University Hospital of Wales , Cardiff , UK. 2b Department of Neuropathology , University Hospital of Wales , Cardiff , UK. 3c Department of Pathology , University Hospital of Wales , Cardiff , UK. Abstract Pineal region lesions are uncommon, and pineal parenchymal tumours (PPT) account for 20-30% of tumours in this... περισσότερα »
The natural compound nujiangexanthone A suppresses mast cell activation and allergic asthma.
Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
The natural compound nujiangexanthone A suppresses mast cell activation and allergic asthma.: *The natural compound nujiangexanthone A suppresses mast cell activation and allergic asthma.* Biochem Pharmacol. 2015 Nov 10; Authors: Lu Y, Cai S, Nie J, Li Y, Shi G, Hao J, Fu W, Tan H, Chen S, Li B, Xu H Abstract Mast cells play an important role in allergic diseases such as asthma, allergic rhinitis and atopic dermatitis. The genus Garciniaof the family Guttiferae is well known as a prolific source of polycyclic polyprenylated acylphloroglucinols and bioactive prenylated xanthones,... περισσότερα »
Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
The natural compound nujiangexanthone A suppresses mast cell activation and allergic asthma.: *The natural compound nujiangexanthone A suppresses mast cell activation and allergic asthma.* Biochem Pharmacol. 2015 Nov 10; Authors: Lu Y, Cai S, Nie J, Li Y, Shi G, Hao J, Fu W, Tan H, Chen S, Li B, Xu H Abstract Mast cells play an important role in allergic diseases such as asthma, allergic rhinitis and atopic dermatitis. The genus Garciniaof the family Guttiferae is well known as a prolific source of polycyclic polyprenylated acylphloroglucinols and bioactive prenylated xanthones,... περισσότερα »
Alterations in peripheral and central components of the auditory brainstem response: a neural assay of tinnitus.
Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
Alterations in peripheral and central components of the auditory brainstem response: a neural assay of tinnitus.: [image: http:--www.plosone.org-images-pone_120x3] [image: http:--www.ncbi.nlm.nih.gov-corehtml-pmc] Related Articles*Alterations in peripheral and central components of the auditory brainstem response: a neural assay of tinnitus.* PLoS One. 2015;10(2):e0117228 Authors: Lowe AS, Walton JP Abstract Chronic tinnitus, or "ringing of the ears", affects upwards of 15% of the adult population. Identifying a cost-effective and objective measure of tinnitus is needed due to l... περισσότερα »
Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
Alterations in peripheral and central components of the auditory brainstem response: a neural assay of tinnitus.: [image: http:--www.plosone.org-images-pone_120x3] [image: http:--www.ncbi.nlm.nih.gov-corehtml-pmc] Related Articles*Alterations in peripheral and central components of the auditory brainstem response: a neural assay of tinnitus.* PLoS One. 2015;10(2):e0117228 Authors: Lowe AS, Walton JP Abstract Chronic tinnitus, or "ringing of the ears", affects upwards of 15% of the adult population. Identifying a cost-effective and objective measure of tinnitus is needed due to l... περισσότερα »
Differential development of oil granulomas
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 1 ώρα
induced by pristane injection in galectin-3 deficient mice via Latest Results for BMC Immunology AbstractBackgroundGalectin-3 is known to be a lectin that plays an important role in inflammatory processes, acting as pro-inflammatory mediator in activation and migration of neutrophils and macrophages, as well as in the phagocytic function of these cells. The injection of mineral oils into the peritoneal cavity of mice, such as 2, 6, 10, 14-tetramethylpentadecane (pristane), induce a chronic granulomatous inflammatory reaction which is rich in macrophages, B cells and peritoneal plasm... περισσότερα »
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 1 ώρα
induced by pristane injection in galectin-3 deficient mice via Latest Results for BMC Immunology AbstractBackgroundGalectin-3 is known to be a lectin that plays an important role in inflammatory processes, acting as pro-inflammatory mediator in activation and migration of neutrophils and macrophages, as well as in the phagocytic function of these cells. The injection of mineral oils into the peritoneal cavity of mice, such as 2, 6, 10, 14-tetramethylpentadecane (pristane), induce a chronic granulomatous inflammatory reaction which is rich in macrophages, B cells and peritoneal plasm... περισσότερα »
Ultrasound Thermography Using Infrared Imaging
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 1 ώρα
Calibration and Evaluation of via ScienceDirect Publication: Ultrasound in Medicine & Biology Publication date: Available online 5 November 2015 *Source:*Ultrasound in Medicine & Biology Author(s): Yi-Sing Hsiao, Cheri X. Deng Real-time monitoring of the spatiotemporal evolution of tissue temperature is important to ensure safe and effective treatment in thermal therapies including hyperthermia and thermal ablation. Ultrasound thermography has been proposed as a non-invasive technique for temperature measurement, and accurate calibration of the temperature-dependent ultrasound signal c... περισσότερα »
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 1 ώρα
Calibration and Evaluation of via ScienceDirect Publication: Ultrasound in Medicine & Biology Publication date: Available online 5 November 2015 *Source:*Ultrasound in Medicine & Biology Author(s): Yi-Sing Hsiao, Cheri X. Deng Real-time monitoring of the spatiotemporal evolution of tissue temperature is important to ensure safe and effective treatment in thermal therapies including hyperthermia and thermal ablation. Ultrasound thermography has been proposed as a non-invasive technique for temperature measurement, and accurate calibration of the temperature-dependent ultrasound signal c... περισσότερα »
Ultrasound-Based Carotid Elastography for Detection of Vulnerable Atherosclerotic Plaques
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 1 ώρα
Validated by Magnetic Resonance Imaging via ScienceDirect Publication: Ultrasound in Medicine & Biology Publication date: Available online 6 November 2015 *Source:*Ultrasound in Medicine & Biology Author(s): Chengwu Huang, Xiaochang Pan, Qiong He, Manwei Huang, Lingyun Huang, Xihai Zhao, Chun Yuan, Jing Bai, Jianwen Luo Ultrasound-based carotid elastography has been developed to estimate the mechanical properties of atherosclerotic plaques. The objective of this study was to evaluate the in vivo capability of carotid elastography in vulnerable plaque detection using high-resolution mag... περισσότερα »
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 1 ώρα
Validated by Magnetic Resonance Imaging via ScienceDirect Publication: Ultrasound in Medicine & Biology Publication date: Available online 6 November 2015 *Source:*Ultrasound in Medicine & Biology Author(s): Chengwu Huang, Xiaochang Pan, Qiong He, Manwei Huang, Lingyun Huang, Xihai Zhao, Chun Yuan, Jing Bai, Jianwen Luo Ultrasound-based carotid elastography has been developed to estimate the mechanical properties of atherosclerotic plaques. The objective of this study was to evaluate the in vivo capability of carotid elastography in vulnerable plaque detection using high-resolution mag... περισσότερα »
Therapeutic Ultrasound Waveforms on Endothelial Function
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 1 ώρα
Effects of Different Therapeutic Ultrasound Waveforms on Endothelial Function in Healthy Volunteers: A Randomized Clinical Trial via ScienceDirect Publication: Ultrasound in Medicine & Biology Publication date: Available online 12 November 2015 *Source:*Ultrasound in Medicine & Biology Author(s): Jeferson Mendes Cruz, Melina Hauck, Ana Paula Cardoso Pereira, Maicon Borges Moraes, Cassio Noronha Martins, Felipe da Silva Paulitsch, Rodrigo Della Méa Plentz, William Peres, Antônio Marcos Vargas da Silva, Luis Ulisses Signori The purpose of this study was to determine the effects of differe... περισσότερα »
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 1 ώρα
Effects of Different Therapeutic Ultrasound Waveforms on Endothelial Function in Healthy Volunteers: A Randomized Clinical Trial via ScienceDirect Publication: Ultrasound in Medicine & Biology Publication date: Available online 12 November 2015 *Source:*Ultrasound in Medicine & Biology Author(s): Jeferson Mendes Cruz, Melina Hauck, Ana Paula Cardoso Pereira, Maicon Borges Moraes, Cassio Noronha Martins, Felipe da Silva Paulitsch, Rodrigo Della Méa Plentz, William Peres, Antônio Marcos Vargas da Silva, Luis Ulisses Signori The purpose of this study was to determine the effects of differe... περισσότερα »
Imaging the Cemento-enamel Junction Using a 20-MHz Ultrasonic Transducer
Alexandros G. SfakianakisστοΚοσμητική ΟδοντοΙατρική και ΓναθοΧειρουργικήΠριν από 1 ώρα
Imaging the Cemento-enamel Junction Using a 20-MHz Ultrasonic Transducer via ScienceDirect Publication: Ultrasound in Medicine & Biology Publication date: Available online 3 November 2015 *Source:*Ultrasound in Medicine & Biology Author(s): Kim-Cuong T. Nguyen, Lawrence H. Le, Neelambar R. Kaipatur, Paul W. Major The cemento-enamel junction (CEJ), which is the intersection between enamel and cementum, is an important landmark in the diagnosis of periodontal disease. Pulse-echo ultrasound was used to image the CEJs of six porcine lower central incisors with a single 20-MHz transducer. A ... περισσότερα »
Alexandros G. SfakianakisστοΚοσμητική ΟδοντοΙατρική και ΓναθοΧειρουργικήΠριν από 1 ώρα
Imaging the Cemento-enamel Junction Using a 20-MHz Ultrasonic Transducer via ScienceDirect Publication: Ultrasound in Medicine & Biology Publication date: Available online 3 November 2015 *Source:*Ultrasound in Medicine & Biology Author(s): Kim-Cuong T. Nguyen, Lawrence H. Le, Neelambar R. Kaipatur, Paul W. Major The cemento-enamel junction (CEJ), which is the intersection between enamel and cementum, is an important landmark in the diagnosis of periodontal disease. Pulse-echo ultrasound was used to image the CEJs of six porcine lower central incisors with a single 20-MHz transducer. A ... περισσότερα »
Virtual Touch Tissue Imaging Quantification Shear Wave Elastography
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 1 ώρα
: Prospective Assessment of Cervical Lymph Nodes via ScienceDirect Publication: Ultrasound in Medicine & Biology Publication date: Available online 6 November 2015 *Source:*Ultrasound in Medicine & Biology Author(s): Kai Lun Cheng, Young Jun Choi, Woo Hyun Shim, Jeong Hyun Lee, Jung Hwan Baek The goal of this study was to prospectively evaluate the diagnostic performance of Virtual Touch tissue imaging quantification (VTIQ) shear wave elastography in the discrimination of benign and malignant cervical lymph nodes in routine clinical practice. Shear wave velocity was analyzed using VTIQ... περισσότερα »
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 1 ώρα
: Prospective Assessment of Cervical Lymph Nodes via ScienceDirect Publication: Ultrasound in Medicine & Biology Publication date: Available online 6 November 2015 *Source:*Ultrasound in Medicine & Biology Author(s): Kai Lun Cheng, Young Jun Choi, Woo Hyun Shim, Jeong Hyun Lee, Jung Hwan Baek The goal of this study was to prospectively evaluate the diagnostic performance of Virtual Touch tissue imaging quantification (VTIQ) shear wave elastography in the discrimination of benign and malignant cervical lymph nodes in routine clinical practice. Shear wave velocity was analyzed using VTIQ... περισσότερα »
Surrogate arterial phase imaging using a long duration (≈1.5 min) radial acquisition T1-weighted sequence: an alternative in patients unable to breath-hold.
Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
Surrogate arterial phase imaging using a long duration (≈1.5 min) radial acquisition T1-weighted sequence: an alternative in patients unable to breath-hold.: *Surrogate arterial phase imaging using a long duration (≈1.5 min) radial acquisition T1-weighted sequence: an alternative in patients unable to breath-hold.* Acta Radiol. 2015 Nov 13; Authors: AlObaidy M, Ramalho M, Busireddy KK, Dale BM, Burke LM, Altun E, Liu B, Semelka RC Abstract BACKGROUND: Pediatric and adult patients unable to suspend respiration generally undergo magnetic resonance (MR) examinations that lack arter...περισσότερα »
Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
Surrogate arterial phase imaging using a long duration (≈1.5 min) radial acquisition T1-weighted sequence: an alternative in patients unable to breath-hold.: *Surrogate arterial phase imaging using a long duration (≈1.5 min) radial acquisition T1-weighted sequence: an alternative in patients unable to breath-hold.* Acta Radiol. 2015 Nov 13; Authors: AlObaidy M, Ramalho M, Busireddy KK, Dale BM, Burke LM, Altun E, Liu B, Semelka RC Abstract BACKGROUND: Pediatric and adult patients unable to suspend respiration generally undergo magnetic resonance (MR) examinations that lack arter...περισσότερα »
Electrophysiological mismatch response recorded in awake pigeons from the avian functional equivalent of the primary auditory cortex.
Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
Electrophysiological mismatch response recorded in awake pigeons from the avian functional equivalent of the primary auditory cortex.: [image: http:--pt.wkhealth.com-pt-pt-core-templa] Related Articles*Electrophysiological mismatch response recorded in awake pigeons from the avian functional equivalent of the primary auditory cortex.* Neuroreport. 2015 Mar 25;26(5):239-44 Authors: Schall U, Müller BW, Kärgel C, Güntürkün O Abstract The neural response to occasional variations in acoustic stimuli in a regular sequence of sounds generates an N-methyl-D-aspartate receptor-modulated ... περισσότερα »
Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
Electrophysiological mismatch response recorded in awake pigeons from the avian functional equivalent of the primary auditory cortex.: [image: http:--pt.wkhealth.com-pt-pt-core-templa] Related Articles*Electrophysiological mismatch response recorded in awake pigeons from the avian functional equivalent of the primary auditory cortex.* Neuroreport. 2015 Mar 25;26(5):239-44 Authors: Schall U, Müller BW, Kärgel C, Güntürkün O Abstract The neural response to occasional variations in acoustic stimuli in a regular sequence of sounds generates an N-methyl-D-aspartate receptor-modulated ... περισσότερα »
Omega 6 fatty acids for the primary prevention of cardiovascular disease.
Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
Omega 6 fatty acids for the primary prevention of cardiovascular disease.: *Omega 6 fatty acids for the primary prevention of cardiovascular disease.* Cochrane Database Syst Rev. 2015 Nov 16;11:CD011094 Authors: Al-Khudairy L, Hartley L, Clar C, Flowers N, Hooper L, Rees K Abstract BACKGROUND: Omega 6 plays a vital role in many physiological functions but there is controversy concerning its effect on cardiovascular disease (CVD) risk. There is conflicting evidence whether increasing or decreasing omega 6 intake results in beneficial effects. OBJECTIVES: The two primary objectives ...περισσότερα »
Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
Omega 6 fatty acids for the primary prevention of cardiovascular disease.: *Omega 6 fatty acids for the primary prevention of cardiovascular disease.* Cochrane Database Syst Rev. 2015 Nov 16;11:CD011094 Authors: Al-Khudairy L, Hartley L, Clar C, Flowers N, Hooper L, Rees K Abstract BACKGROUND: Omega 6 plays a vital role in many physiological functions but there is controversy concerning its effect on cardiovascular disease (CVD) risk. There is conflicting evidence whether increasing or decreasing omega 6 intake results in beneficial effects. OBJECTIVES: The two primary objectives ...περισσότερα »
cVEMPs: a systematic review and meta-analysis.
Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
cVEMPs: a systematic review and meta-analysis.: [image: http:--www.tandfonline.com-templates-jsp] Related Articles*cVEMPs: a systematic review and meta-analysis.* Int J Audiol. 2015 Mar;54(3):143-51 Authors: Meyer N, Vinck B, Heinze B Abstract OBJECTIVE: A systematic literature review and meta-analysis was performed to determine the effect of stimulus type, SCM muscle activation method, transducer type, and method to control SCM muscle EMG level on response parameter values for 0.1-ms click-evoked and 500-Hz tone burst cVEMPs. A description of normative response values was attemp... περισσότερα »
Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
cVEMPs: a systematic review and meta-analysis.: [image: http:--www.tandfonline.com-templates-jsp] Related Articles*cVEMPs: a systematic review and meta-analysis.* Int J Audiol. 2015 Mar;54(3):143-51 Authors: Meyer N, Vinck B, Heinze B Abstract OBJECTIVE: A systematic literature review and meta-analysis was performed to determine the effect of stimulus type, SCM muscle activation method, transducer type, and method to control SCM muscle EMG level on response parameter values for 0.1-ms click-evoked and 500-Hz tone burst cVEMPs. A description of normative response values was attemp... περισσότερα »
A novel HSV-2 subunit vaccine induces GLA-dependent CD4 and CD8 T cell responses and protective immunity in mice and guinea pigs.
Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
A novel HSV-2 subunit vaccine induces GLA-dependent CD4 and CD8 T cell responses and protective immunity in mice and guinea pigs.: *A novel HSV-2 subunit vaccine induces GLA-dependent CD4 and CD8 T cell responses and protective immunity in mice and guinea pigs.* Vaccine. 2015 Nov 10; Authors: Odegard JM, Flynn PA, Campbell DJ, Robbins SH, Dong L, Wang K, Ter Meulen J, Cohen JI, Koelle DM Abstract BACKGROUND/OBJECTIVES: There is currently no licensed prophylactic or therapeutic vaccine for HSV-2 infection. METHODS: We developed a novel preclinical vaccine candidate, G103, consist... περισσότερα »
Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
A novel HSV-2 subunit vaccine induces GLA-dependent CD4 and CD8 T cell responses and protective immunity in mice and guinea pigs.: *A novel HSV-2 subunit vaccine induces GLA-dependent CD4 and CD8 T cell responses and protective immunity in mice and guinea pigs.* Vaccine. 2015 Nov 10; Authors: Odegard JM, Flynn PA, Campbell DJ, Robbins SH, Dong L, Wang K, Ter Meulen J, Cohen JI, Koelle DM Abstract BACKGROUND/OBJECTIVES: There is currently no licensed prophylactic or therapeutic vaccine for HSV-2 infection. METHODS: We developed a novel preclinical vaccine candidate, G103, consist... περισσότερα »
Reducing pain at the time of vaccination: WHO position paper, September 2015-Recommendations.
Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
Reducing pain at the time of vaccination: WHO position paper, September 2015-Recommendations.: *Reducing pain at the time of vaccination: WHO position paper, September 2015-Recommendations.* Vaccine. 2015 Nov 10; Authors: Marti M Abstract This article presents the World Health Organization's (WHO) recommendations for pain mitigation at the time of vaccination from the WHO position paper on reducing pain at the time of vaccination: WHO position paper-September 2015, recently published in the Weekly Epidemiological Record (Wkly Epidemiol Rec, 2015;90(39):505). This position paper ...περισσότερα »
Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
Reducing pain at the time of vaccination: WHO position paper, September 2015-Recommendations.: *Reducing pain at the time of vaccination: WHO position paper, September 2015-Recommendations.* Vaccine. 2015 Nov 10; Authors: Marti M Abstract This article presents the World Health Organization's (WHO) recommendations for pain mitigation at the time of vaccination from the WHO position paper on reducing pain at the time of vaccination: WHO position paper-September 2015, recently published in the Weekly Epidemiological Record (Wkly Epidemiol Rec, 2015;90(39):505). This position paper ...περισσότερα »
Orbitomaxillary mass after repair of the orbital floor.
Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
Orbitomaxillary mass after repair of the orbital floor.: [image: http:--linkinghub.elsevier.com-ihub-imag] Related Articles*Orbitomaxillary mass after repair of the orbital floor.* Br J Oral Maxillofac Surg. 2014 Dec;52(10):977-9 Authors: Verma S, Garg A, Nastri A Abstract A 48-year-old man presented with an orbitomaxillary mass 31 years after repair of the orbital floor. He gave a history of progressive diplopia and paraesthesiae of the right infraorbital nerve. He also noted improvement in his long-standing post-traumatic enophthalmos. Imaging showed a large orbitomaxillary cys... περισσότερα »
Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
Orbitomaxillary mass after repair of the orbital floor.: [image: http:--linkinghub.elsevier.com-ihub-imag] Related Articles*Orbitomaxillary mass after repair of the orbital floor.* Br J Oral Maxillofac Surg. 2014 Dec;52(10):977-9 Authors: Verma S, Garg A, Nastri A Abstract A 48-year-old man presented with an orbitomaxillary mass 31 years after repair of the orbital floor. He gave a history of progressive diplopia and paraesthesiae of the right infraorbital nerve. He also noted improvement in his long-standing post-traumatic enophthalmos. Imaging showed a large orbitomaxillary cys... περισσότερα »
Correction of an alar web with a feather-edge rolled-in flap.
Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
Correction of an alar web with a feather-edge rolled-in flap.: [image: http:--pt.wkhealth.com-pt-pt-core-templa] Related Articles*Correction of an alar web with a feather-edge rolled-in flap.* J Craniofac Surg. 2014 Nov;25(6):2192-5 Authors: Park JL, Oh CH, Hwang K, Kim DJ, Jeong JM, Heo WY, Park CG Abstract The aim of this study was to see the histological nature of the alar web and to introduce a featheredged rolled-in flap to reduce the alar web.On a cadaver, the perpendicular section of the alar web revealed a thickened dermis portion on both the skin side and the nasal side d... περισσότερα »
Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
Correction of an alar web with a feather-edge rolled-in flap.: [image: http:--pt.wkhealth.com-pt-pt-core-templa] Related Articles*Correction of an alar web with a feather-edge rolled-in flap.* J Craniofac Surg. 2014 Nov;25(6):2192-5 Authors: Park JL, Oh CH, Hwang K, Kim DJ, Jeong JM, Heo WY, Park CG Abstract The aim of this study was to see the histological nature of the alar web and to introduce a featheredged rolled-in flap to reduce the alar web.On a cadaver, the perpendicular section of the alar web revealed a thickened dermis portion on both the skin side and the nasal side d... περισσότερα »
A new persistent suture technique for correction of caudal septal dislocation.
Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
A new persistent suture technique for correction of caudal septal dislocation.: [image: http:--pt.wkhealth.com-pt-pt-core-templa] Related Articles*A new persistent suture technique for correction of caudal septal dislocation.* J Craniofac Surg. 2014 Nov;25(6):2169-71 Authors: Batioglu-Karaaltin A, Yigit O, Donmez Z Abstract INTRODUCTION: Caudal septal dislocation is both a functional and an aesthetic problem. The caudal septum that causes nasal obstruction displaces the right or left of columella. Despite the various maneuvers currently available for treatment, this issue is stil... περισσότερα »
Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
A new persistent suture technique for correction of caudal septal dislocation.: [image: http:--pt.wkhealth.com-pt-pt-core-templa] Related Articles*A new persistent suture technique for correction of caudal septal dislocation.* J Craniofac Surg. 2014 Nov;25(6):2169-71 Authors: Batioglu-Karaaltin A, Yigit O, Donmez Z Abstract INTRODUCTION: Caudal septal dislocation is both a functional and an aesthetic problem. The caudal septum that causes nasal obstruction displaces the right or left of columella. Despite the various maneuvers currently available for treatment, this issue is stil... περισσότερα »
Management of frontal sinus fractures: treatment modality changes at a level I trauma center.
Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
Management of frontal sinus fractures: treatment modality changes at a level I trauma center.: [image: http:--pt.wkhealth.com-pt-pt-core-templa] Related Articles*Management of frontal sinus fractures: treatment modality changes at a level I trauma center.* J Craniofac Surg. 2014 Nov;25(6):2038-42 Authors: Fox PM, Garza R, Dusch M, Hwang PH, Girod S Abstract The optimal management of frontal sinus fractures remains controversial, and previously accepted indications for surgical intervention are being challenged. The goals of this study were to determine how frontal sinus fracture... περισσότερα »
Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
Management of frontal sinus fractures: treatment modality changes at a level I trauma center.: [image: http:--pt.wkhealth.com-pt-pt-core-templa] Related Articles*Management of frontal sinus fractures: treatment modality changes at a level I trauma center.* J Craniofac Surg. 2014 Nov;25(6):2038-42 Authors: Fox PM, Garza R, Dusch M, Hwang PH, Girod S Abstract The optimal management of frontal sinus fractures remains controversial, and previously accepted indications for surgical intervention are being challenged. The goals of this study were to determine how frontal sinus fracture... περισσότερα »
Pedicled lateral nasal wall flap for the reconstruction of the nasal septum perforation. A radio-anatomical study.
Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
Pedicled lateral nasal wall flap for the reconstruction of the nasal septum perforation. A radio-anatomical study.: Related Articles*Pedicled lateral nasal wall flap for the reconstruction of the nasal septum perforation. A radio-anatomical study.* Rhinology. 2015 Sep;53(3):235-41 Authors: Alobid I, Mason E, Solares CA, Prevedello D, Enseñat J, De Notaris M, Prats-Galino A, Bernal-Sprekelsen M, Carrau R Abstract INTRODUCTION: The aim of this radio-anatomical study is to ensure that the potential donor area of the pedicled lateral nasal wall flap (PLNW) is adequate to reconstruct ... περισσότερα »
Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
Pedicled lateral nasal wall flap for the reconstruction of the nasal septum perforation. A radio-anatomical study.: Related Articles*Pedicled lateral nasal wall flap for the reconstruction of the nasal septum perforation. A radio-anatomical study.* Rhinology. 2015 Sep;53(3):235-41 Authors: Alobid I, Mason E, Solares CA, Prevedello D, Enseñat J, De Notaris M, Prats-Galino A, Bernal-Sprekelsen M, Carrau R Abstract INTRODUCTION: The aim of this radio-anatomical study is to ensure that the potential donor area of the pedicled lateral nasal wall flap (PLNW) is adequate to reconstruct ... περισσότερα »
Vestibular Schwannoma: The Evolution of Hearing and Tumor Size in Natural Course and after Treatment by LINAC Stereotactic Radiosurgery.
Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
Vestibular Schwannoma: The Evolution of Hearing and Tumor Size in Natural Course and after Treatment by LINAC Stereotactic Radiosurgery.: *Vestibular Schwannoma: The Evolution of Hearing and Tumor Size in Natural Course and after Treatment by LINAC Stereotactic Radiosurgery.* Audiol Neurootol. 2015 Nov 17;20(6):406-415 Authors: Ikonomidis C, Pica A, Bloch J, Maire R Abstract OBJECTIVE: To review the natural course of tumor size and hearing during conservative management of 151 patients with unilateral vestibular schwannoma (VS), and to evaluate the same parameters for the part of ... περισσότερα »
Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
Vestibular Schwannoma: The Evolution of Hearing and Tumor Size in Natural Course and after Treatment by LINAC Stereotactic Radiosurgery.: *Vestibular Schwannoma: The Evolution of Hearing and Tumor Size in Natural Course and after Treatment by LINAC Stereotactic Radiosurgery.* Audiol Neurootol. 2015 Nov 17;20(6):406-415 Authors: Ikonomidis C, Pica A, Bloch J, Maire R Abstract OBJECTIVE: To review the natural course of tumor size and hearing during conservative management of 151 patients with unilateral vestibular schwannoma (VS), and to evaluate the same parameters for the part of ... περισσότερα »
Correction of an alar web with a feather-edge rolled-in flap.
Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
Correction of an alar web with a feather-edge rolled-in flap.: [image: http:--pt.wkhealth.com-pt-pt-core-templa] Related Articles*Correction of an alar web with a feather-edge rolled-in flap.* J Craniofac Surg. 2014 Nov;25(6):2192-5 Authors: Park JL, Oh CH, Hwang K, Kim DJ, Jeong JM, Heo WY, Park CG Abstract The aim of this study was to see the histological nature of the alar web and to introduce a featheredged rolled-in flap to reduce the alar web.On a cadaver, the perpendicular section of the alar web revealed a thickened dermis portion on both the skin side and the nasal side d... περισσότερα »
Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
Correction of an alar web with a feather-edge rolled-in flap.: [image: http:--pt.wkhealth.com-pt-pt-core-templa] Related Articles*Correction of an alar web with a feather-edge rolled-in flap.* J Craniofac Surg. 2014 Nov;25(6):2192-5 Authors: Park JL, Oh CH, Hwang K, Kim DJ, Jeong JM, Heo WY, Park CG Abstract The aim of this study was to see the histological nature of the alar web and to introduce a featheredged rolled-in flap to reduce the alar web.On a cadaver, the perpendicular section of the alar web revealed a thickened dermis portion on both the skin side and the nasal side d... περισσότερα »
A new persistent suture technique for correction of caudal septal dislocation.
Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
A new persistent suture technique for correction of caudal septal dislocation.: [image: http:--pt.wkhealth.com-pt-pt-core-templa] Related Articles*A new persistent suture technique for correction of caudal septal dislocation.* J Craniofac Surg. 2014 Nov;25(6):2169-71 Authors: Batioglu-Karaaltin A, Yigit O, Donmez Z Abstract INTRODUCTION: Caudal septal dislocation is both a functional and an aesthetic problem. The caudal septum that causes nasal obstruction displaces the right or left of columella. Despite the various maneuvers currently available for treatment, this issue is stil... περισσότερα »
Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
A new persistent suture technique for correction of caudal septal dislocation.: [image: http:--pt.wkhealth.com-pt-pt-core-templa] Related Articles*A new persistent suture technique for correction of caudal septal dislocation.* J Craniofac Surg. 2014 Nov;25(6):2169-71 Authors: Batioglu-Karaaltin A, Yigit O, Donmez Z Abstract INTRODUCTION: Caudal septal dislocation is both a functional and an aesthetic problem. The caudal septum that causes nasal obstruction displaces the right or left of columella. Despite the various maneuvers currently available for treatment, this issue is stil... περισσότερα »
Nasal reconstruction with the paramedian forehead flap using the aesthetic subunits principle.
Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
Nasal reconstruction with the paramedian forehead flap using the aesthetic subunits principle.: [image: http:--pt.wkhealth.com-pt-pt-core-templa] Related Articles*Nasal reconstruction with the paramedian forehead flap using the aesthetic subunits principle.* J Craniofac Surg. 2014 Nov;25(6):2070-3 Authors: de Pochat VD, Alonso N, Ribeiro EB, Figueiredo BS, de Magaldi EN, Cunha MS, Meneses JV Abstract Reconstruction of nasal defects is challenging because it requires covering skin, supporting framework, and lining. Traditionally, the forehead flaps are transferred in 2 stages; ho... περισσότερα »
Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
Nasal reconstruction with the paramedian forehead flap using the aesthetic subunits principle.: [image: http:--pt.wkhealth.com-pt-pt-core-templa] Related Articles*Nasal reconstruction with the paramedian forehead flap using the aesthetic subunits principle.* J Craniofac Surg. 2014 Nov;25(6):2070-3 Authors: de Pochat VD, Alonso N, Ribeiro EB, Figueiredo BS, de Magaldi EN, Cunha MS, Meneses JV Abstract Reconstruction of nasal defects is challenging because it requires covering skin, supporting framework, and lining. Traditionally, the forehead flaps are transferred in 2 stages; ho... περισσότερα »
Pedicled lateral nasal wall flap for the reconstruction of the nasal septum perforation. A radio-anatomical study.
Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
Pedicled lateral nasal wall flap for the reconstruction of the nasal septum perforation. A radio-anatomical study.: Related Articles*Pedicled lateral nasal wall flap for the reconstruction of the nasal septum perforation. A radio-anatomical study.* Rhinology. 2015 Sep;53(3):235-41 Authors: Alobid I, Mason E, Solares CA, Prevedello D, Enseñat J, De Notaris M, Prats-Galino A, Bernal-Sprekelsen M, Carrau R Abstract INTRODUCTION: The aim of this radio-anatomical study is to ensure that the potential donor area of the pedicled lateral nasal wall flap (PLNW) is adequate to reconstruct ... περισσότερα »
Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
Pedicled lateral nasal wall flap for the reconstruction of the nasal septum perforation. A radio-anatomical study.: Related Articles*Pedicled lateral nasal wall flap for the reconstruction of the nasal septum perforation. A radio-anatomical study.* Rhinology. 2015 Sep;53(3):235-41 Authors: Alobid I, Mason E, Solares CA, Prevedello D, Enseñat J, De Notaris M, Prats-Galino A, Bernal-Sprekelsen M, Carrau R Abstract INTRODUCTION: The aim of this radio-anatomical study is to ensure that the potential donor area of the pedicled lateral nasal wall flap (PLNW) is adequate to reconstruct ... περισσότερα »
The effect of "Pyriform Turbinoplasty" on nasal airflow using a virtual model.
Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
The effect of "Pyriform Turbinoplasty" on nasal airflow using a virtual model.: Related Articles*The effect of "Pyriform Turbinoplasty" on nasal airflow using a virtual model.* Rhinology. 2015 Sep;53(3):242-8 Authors: Simmen D, Sommer F, Briner HR, Jones N, Kröger R, Hoffmann TK, Lindemann J Abstract BACKGROUND: A new procedure, pyriform turbinoplasty, is described and nasal airflow is measured before and after this procedure in a virtual model. METHODOLOGY: Pyriform turbinoplasty is the submucosal reduction of the bone of the frontal process of the maxilla and the lacrimal bone... περισσότερα »
Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
The effect of "Pyriform Turbinoplasty" on nasal airflow using a virtual model.: Related Articles*The effect of "Pyriform Turbinoplasty" on nasal airflow using a virtual model.* Rhinology. 2015 Sep;53(3):242-8 Authors: Simmen D, Sommer F, Briner HR, Jones N, Kröger R, Hoffmann TK, Lindemann J Abstract BACKGROUND: A new procedure, pyriform turbinoplasty, is described and nasal airflow is measured before and after this procedure in a virtual model. METHODOLOGY: Pyriform turbinoplasty is the submucosal reduction of the bone of the frontal process of the maxilla and the lacrimal bone... περισσότερα »
ELANE mutant-specific activation of different UPR pathways in congenital neutropenia.
Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
ELANE mutant-specific activation of different UPR pathways in congenital neutropenia.: *ELANE mutant-specific activation of different UPR pathways in congenital neutropenia.* Br J Haematol. 2015 Nov 16; Authors: Nustede R, Klimiankou M, Klimenkova O, Kuznetsova I, Zeidler C, Welte K, Skokowa J Abstract A number of studies have demonstrated induction of the unfolded protein response (UPR) in patients with severe congenital neutropenia (CN) harbouring mutations of ELANE, encoding neutrophil elastase. Why UPR is not activated in patients with cyclic neutropenia (CyN) carrying the s...περισσότερα »
Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
ELANE mutant-specific activation of different UPR pathways in congenital neutropenia.: *ELANE mutant-specific activation of different UPR pathways in congenital neutropenia.* Br J Haematol. 2015 Nov 16; Authors: Nustede R, Klimiankou M, Klimenkova O, Kuznetsova I, Zeidler C, Welte K, Skokowa J Abstract A number of studies have demonstrated induction of the unfolded protein response (UPR) in patients with severe congenital neutropenia (CN) harbouring mutations of ELANE, encoding neutrophil elastase. Why UPR is not activated in patients with cyclic neutropenia (CyN) carrying the s...περισσότερα »
Anti-inflammatory properties of Morus bombycis Koidzumi via inhibiting IFN-β signaling and NLRP3 inflammasome activation.
Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
Anti-inflammatory properties of Morus bombycis Koidzumi via inhibiting IFN-β signaling and NLRP3 inflammasome activation.: *Anti-inflammatory properties of Morus bombycis Koidzumi via inhibiting IFN-β signaling and NLRP3 inflammasome activation.* J Ethnopharmacol. 2015 Nov 10; Authors: Oh NH, Han JW, Shim DW, Sim EJ, Koppula S, Kwak SB, Kim MK, Kim YK, Jiang J, Park PJ, Kang TB, Lee KH Abstract ETHNOPHARMACOLOGICAL RELEVANCE: Morus bombycis Koidzumi (M. bombycis, Moraceae) has been used in Asian countries as a traditional medicine for the treatment of hypertension, diabetes, and ... περισσότερα »
Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
Anti-inflammatory properties of Morus bombycis Koidzumi via inhibiting IFN-β signaling and NLRP3 inflammasome activation.: *Anti-inflammatory properties of Morus bombycis Koidzumi via inhibiting IFN-β signaling and NLRP3 inflammasome activation.* J Ethnopharmacol. 2015 Nov 10; Authors: Oh NH, Han JW, Shim DW, Sim EJ, Koppula S, Kwak SB, Kim MK, Kim YK, Jiang J, Park PJ, Kang TB, Lee KH Abstract ETHNOPHARMACOLOGICAL RELEVANCE: Morus bombycis Koidzumi (M. bombycis, Moraceae) has been used in Asian countries as a traditional medicine for the treatment of hypertension, diabetes, and ... περισσότερα »
DXXK exerts anti-inflammatory effects by inhibiting the lipopolysaccharide-induced NF-κB/COX-2 signalling pathway and the expression of inflammatory mediators.
Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
DXXK exerts anti-inflammatory effects by inhibiting the lipopolysaccharide-induced NF-κB/COX-2 signalling pathway and the expression of inflammatory mediators.: *DXXK exerts anti-inflammatory effects by inhibiting the lipopolysaccharide-induced NF-κB/COX-2 signalling pathway and the expression of inflammatory mediators.* J Ethnopharmacol. 2015 Nov 10; Authors: Yu Y, Li X, Qu L, Chen Y, Dai Y, Wang M, Zou W Abstract ETHNOPHARMACOLOGICAL RELEVANCE: Diao Xin Xue Kang (DXXK) is the active pharmaceutical ingredient of the traditional Chinese medicinal product DXXK capsules, which hav...περισσότερα »
Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
DXXK exerts anti-inflammatory effects by inhibiting the lipopolysaccharide-induced NF-κB/COX-2 signalling pathway and the expression of inflammatory mediators.: *DXXK exerts anti-inflammatory effects by inhibiting the lipopolysaccharide-induced NF-κB/COX-2 signalling pathway and the expression of inflammatory mediators.* J Ethnopharmacol. 2015 Nov 10; Authors: Yu Y, Li X, Qu L, Chen Y, Dai Y, Wang M, Zou W Abstract ETHNOPHARMACOLOGICAL RELEVANCE: Diao Xin Xue Kang (DXXK) is the active pharmaceutical ingredient of the traditional Chinese medicinal product DXXK capsules, which hav...περισσότερα »
Herbs against testosterone 5α-reductase and effects of Cacumen platycladi on hair re-growth
Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
Inhibitory activities of some traditional Chinese herbs against testosterone 5α-reductase and effects of Cacumen platycladi on hair re-growth in testosterone-treated mice.: *Inhibitory activities of some traditional Chinese herbs against testosterone 5α-reductase and effects of Cacumen platycladi on hair re-growth in testosterone-treated mice.* J Ethnopharmacol. 2015 Nov 10; Authors: Zhang B, Zhang RW, Yin XQ, Lao ZZ, Zhang Z, Wu QG, Yu LW, Lai XP, Wan YH, Li G Abstract ETHNOPHARMACOLOGICAL RELEVANCE: Many traditional Chinese medicines (TCM) have been used for hundreds of years ... περισσότερα »
Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
Inhibitory activities of some traditional Chinese herbs against testosterone 5α-reductase and effects of Cacumen platycladi on hair re-growth in testosterone-treated mice.: *Inhibitory activities of some traditional Chinese herbs against testosterone 5α-reductase and effects of Cacumen platycladi on hair re-growth in testosterone-treated mice.* J Ethnopharmacol. 2015 Nov 10; Authors: Zhang B, Zhang RW, Yin XQ, Lao ZZ, Zhang Z, Wu QG, Yu LW, Lai XP, Wan YH, Li G Abstract ETHNOPHARMACOLOGICAL RELEVANCE: Many traditional Chinese medicines (TCM) have been used for hundreds of years ... περισσότερα »
Adriamycin-induced nephropathy
Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
Lingzhilactones from Ganoderma lingzhi ameliorate adriamycin-induced nephropathy in mice.: *Lingzhilactones from Ganoderma lingzhi ameliorate adriamycin-induced nephropathy in mice.* J Ethnopharmacol. 2015 Nov 10; Authors: Yan YM, Wang XL, Zhou LL, Zhou FJ, Li R, Tian Y, Zuo ZL, Fang P, Chung AC, Hou FF, Cheng YX Abstract ETHNOPHARMACOLOGICAL RELEVANCE: Several Ganoderma fungi are well-known for their medical uses to treat cancer, insomnia and kidney disease in East Asia. Triperpenoids and polysaccharides have been considered for a long time to be the major active components of ... περισσότερα »
Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
Lingzhilactones from Ganoderma lingzhi ameliorate adriamycin-induced nephropathy in mice.: *Lingzhilactones from Ganoderma lingzhi ameliorate adriamycin-induced nephropathy in mice.* J Ethnopharmacol. 2015 Nov 10; Authors: Yan YM, Wang XL, Zhou LL, Zhou FJ, Li R, Tian Y, Zuo ZL, Fang P, Chung AC, Hou FF, Cheng YX Abstract ETHNOPHARMACOLOGICAL RELEVANCE: Several Ganoderma fungi are well-known for their medical uses to treat cancer, insomnia and kidney disease in East Asia. Triperpenoids and polysaccharides have been considered for a long time to be the major active components of ... περισσότερα »
Gastroprotective effects and antimicrobial activity of Lithraea molleoides and isolated compounds against Helicobacter pylori.
Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
Gastroprotective effects and antimicrobial activity of Lithraea molleoides and isolated compounds against Helicobacter pylori.: *Gastroprotective effects and antimicrobial activity of Lithraea molleoides and isolated compounds against Helicobacter pylori.* J Ethnopharmacol. 2015 Nov 10; Authors: Garro MF, Ibáñez AG, Vega AE, Sosa AC, Pelzer L, Saad JR, Maria AO Abstract ETHNOPHARMACOLOGICAL RELEVANCE: Lithraea molleoides (Vell.) Engl. (Anacardiaceae) is a medicinal plant traditionally used in South America to treat various ailments, including diseases of the digestive system. AIM... περισσότερα »
Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
Gastroprotective effects and antimicrobial activity of Lithraea molleoides and isolated compounds against Helicobacter pylori.: *Gastroprotective effects and antimicrobial activity of Lithraea molleoides and isolated compounds against Helicobacter pylori.* J Ethnopharmacol. 2015 Nov 10; Authors: Garro MF, Ibáñez AG, Vega AE, Sosa AC, Pelzer L, Saad JR, Maria AO Abstract ETHNOPHARMACOLOGICAL RELEVANCE: Lithraea molleoides (Vell.) Engl. (Anacardiaceae) is a medicinal plant traditionally used in South America to treat various ailments, including diseases of the digestive system. AIM... περισσότερα »
Evaluation of platelet distribution width in chronic obstructive pulmonary disease patients with pulmonary embolism.
Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
Evaluation of platelet distribution width in chronic obstructive pulmonary disease patients with pulmonary embolism.: *Evaluation of platelet distribution width in chronic obstructive pulmonary disease patients with pulmonary embolism.* Biomark Med. 2015 Nov 16; Authors: Wang M, Zhang J, Ji Q, Yang Q, Zhao F, Li W, Chang HT, Xie X Abstract BACKGROUND: Platelets play an important role in the pathogenesis of pulmonary embolism (PE). We aimed to investigate whether there is a correlation between platelet distribution width (PDW) and chronic obstructive pulmonary disease (COPD) patie... περισσότερα »
Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
Evaluation of platelet distribution width in chronic obstructive pulmonary disease patients with pulmonary embolism.: *Evaluation of platelet distribution width in chronic obstructive pulmonary disease patients with pulmonary embolism.* Biomark Med. 2015 Nov 16; Authors: Wang M, Zhang J, Ji Q, Yang Q, Zhao F, Li W, Chang HT, Xie X Abstract BACKGROUND: Platelets play an important role in the pathogenesis of pulmonary embolism (PE). We aimed to investigate whether there is a correlation between platelet distribution width (PDW) and chronic obstructive pulmonary disease (COPD) patie... περισσότερα »
Adult Oral Health Programs
Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
Adult Oral Health Programs in Japanese Municipalities: Factors Associated with Self-Rated Effectiveness.: *Adult Oral Health Programs in Japanese Municipalities: Factors Associated with Self-Rated Effectiveness.* Tohoku J Exp Med. 2015;237(4):259-266 Authors: Yamamoto T, Fuchida S, Aida J, Kondo K, Hirata Y Abstract Health Japan 21 plan establishes specific targets for aspects of health including oral health for 2010, in an effort to increase health expectancy. Despite this, there has been insufficient improvement in oral health status in adults. The objective of this cross-secti...περισσότερα »
Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
Adult Oral Health Programs in Japanese Municipalities: Factors Associated with Self-Rated Effectiveness.: *Adult Oral Health Programs in Japanese Municipalities: Factors Associated with Self-Rated Effectiveness.* Tohoku J Exp Med. 2015;237(4):259-266 Authors: Yamamoto T, Fuchida S, Aida J, Kondo K, Hirata Y Abstract Health Japan 21 plan establishes specific targets for aspects of health including oral health for 2010, in an effort to increase health expectancy. Despite this, there has been insufficient improvement in oral health status in adults. The objective of this cross-secti...περισσότερα »
Minimally Invasive Treatment for Hard Palate-Invading Maxillary Keratocystic Odontogenic Tumor.
Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
Minimally Invasive Treatment for Hard Palate-Invading Maxillary Keratocystic Odontogenic Tumor.: *Minimally Invasive Treatment for Hard Palate-Invading Maxillary Keratocystic Odontogenic Tumor.* Tohoku J Exp Med. 2015;237(4):267-272 Authors: Nomura K, Arakawa K, Fujishima F, Yamazaki Y, Ozawa D, Nomura Y, Hidaka H, Yoshida N, Katori Y Abstract Keratocystic odontogenic tumor (KCOT) is one of the benign developmental odontogenic cystic lesions arising from impacted teeth. In comparison to other odontogenic cysts, such as radicular cysts and dentigerous cysts, KCOT is known to be m... περισσότερα »
Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
Minimally Invasive Treatment for Hard Palate-Invading Maxillary Keratocystic Odontogenic Tumor.: *Minimally Invasive Treatment for Hard Palate-Invading Maxillary Keratocystic Odontogenic Tumor.* Tohoku J Exp Med. 2015;237(4):267-272 Authors: Nomura K, Arakawa K, Fujishima F, Yamazaki Y, Ozawa D, Nomura Y, Hidaka H, Yoshida N, Katori Y Abstract Keratocystic odontogenic tumor (KCOT) is one of the benign developmental odontogenic cystic lesions arising from impacted teeth. In comparison to other odontogenic cysts, such as radicular cysts and dentigerous cysts, KCOT is known to be m... περισσότερα »
Early Bimodal Stimulation Benefits Language Acquisition for Children With Cochlear Implants.
Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
Early Bimodal Stimulation Benefits Language Acquisition for Children With Cochlear Implants.: *Early Bimodal Stimulation Benefits Language Acquisition for Children With Cochlear Implants.* Otol Neurotol. 2015 Nov 4; Authors: Moberly AC, Lowenstein JH, Nittrouer S Abstract HYPOTHESIS: Adding a low-frequency acoustic signal to the cochlear implant (CI) signal (i.e., bimodal stimulation) for a period of time early in life improves language acquisition. BACKGROUND: Children must acquire sensitivity to the phonemic units of language to develop most language-related skills, including ... περισσότερα »
Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
Early Bimodal Stimulation Benefits Language Acquisition for Children With Cochlear Implants.: *Early Bimodal Stimulation Benefits Language Acquisition for Children With Cochlear Implants.* Otol Neurotol. 2015 Nov 4; Authors: Moberly AC, Lowenstein JH, Nittrouer S Abstract HYPOTHESIS: Adding a low-frequency acoustic signal to the cochlear implant (CI) signal (i.e., bimodal stimulation) for a period of time early in life improves language acquisition. BACKGROUND: Children must acquire sensitivity to the phonemic units of language to develop most language-related skills, including ... περισσότερα »
Bilateral Changes of Spontaneous Activity Within the Central Auditory Pathway Upon Chronic Unilateral Intracochlear Electrical Stimulation.
Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
Bilateral Changes of Spontaneous Activity Within the Central Auditory Pathway Upon Chronic Unilateral Intracochlear Electrical Stimulation.: *Bilateral Changes of Spontaneous Activity Within the Central Auditory Pathway Upon Chronic Unilateral Intracochlear Electrical Stimulation.* Otol Neurotol. 2015 Nov 4; Authors: Basta D, Götze R, Gröschel M, Jansen S, Janke O, Tzschentke B, Boyle P, Ernst A Abstract OBJECTIVES: In recent years, cochlear implants have been applied successfully for the treatment of unilateral hearing loss with quite surprising benefit. One reason for this succ... περισσότερα »
Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
Bilateral Changes of Spontaneous Activity Within the Central Auditory Pathway Upon Chronic Unilateral Intracochlear Electrical Stimulation.: *Bilateral Changes of Spontaneous Activity Within the Central Auditory Pathway Upon Chronic Unilateral Intracochlear Electrical Stimulation.* Otol Neurotol. 2015 Nov 4; Authors: Basta D, Götze R, Gröschel M, Jansen S, Janke O, Tzschentke B, Boyle P, Ernst A Abstract OBJECTIVES: In recent years, cochlear implants have been applied successfully for the treatment of unilateral hearing loss with quite surprising benefit. One reason for this succ... περισσότερα »
Histopathologic Findings in Peripheral Vestibular System From Patients With Systemic Lupus Erythematosus: A Human Temporal Bone Study.
Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
Histopathologic Findings in Peripheral Vestibular System From Patients With Systemic Lupus Erythematosus: A Human Temporal Bone Study.: *Histopathologic Findings in Peripheral Vestibular System From Patients With Systemic Lupus Erythematosus: A Human Temporal Bone Study.* Otol Neurotol. 2015 Nov 4; Authors: Kariya S, Hzl Ö, Kaya S, Hzl P, Nishizaki K, Paparella MM, Cureoglu S Abstract HYPOTHESIS: We hypothesized that a pathologic condition exists in vestibular hair cells in human temporal bones from patients with systemic lupus erythematosus (SLE). BACKGROUND: A significant asso... περισσότερα »
Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
Histopathologic Findings in Peripheral Vestibular System From Patients With Systemic Lupus Erythematosus: A Human Temporal Bone Study.: *Histopathologic Findings in Peripheral Vestibular System From Patients With Systemic Lupus Erythematosus: A Human Temporal Bone Study.* Otol Neurotol. 2015 Nov 4; Authors: Kariya S, Hzl Ö, Kaya S, Hzl P, Nishizaki K, Paparella MM, Cureoglu S Abstract HYPOTHESIS: We hypothesized that a pathologic condition exists in vestibular hair cells in human temporal bones from patients with systemic lupus erythematosus (SLE). BACKGROUND: A significant asso... περισσότερα »
Eustachian Tube Mucosal Inflammation Scale Validation Based on Digital Video Images.
Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
Eustachian Tube Mucosal Inflammation Scale Validation Based on Digital Video Images.: *Eustachian Tube Mucosal Inflammation Scale Validation Based on Digital Video Images.* Otol Neurotol. 2015 Nov 4; Authors: Kivekäs I, Pöyhönen L, Aarnisalo A, Rautiainen M, Poe D Abstract BACKGROUND: The most common cause for Eustachian tube dilatory dysfunction is mucosal inflammation. The aim of this study was to validate a scale for Eustachian tube mucosal inflammation, based on digital video clips obtained during diagnostic rigid endoscopy. METHODS: A previously described four-step scale fo... περισσότερα »
Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
Eustachian Tube Mucosal Inflammation Scale Validation Based on Digital Video Images.: *Eustachian Tube Mucosal Inflammation Scale Validation Based on Digital Video Images.* Otol Neurotol. 2015 Nov 4; Authors: Kivekäs I, Pöyhönen L, Aarnisalo A, Rautiainen M, Poe D Abstract BACKGROUND: The most common cause for Eustachian tube dilatory dysfunction is mucosal inflammation. The aim of this study was to validate a scale for Eustachian tube mucosal inflammation, based on digital video clips obtained during diagnostic rigid endoscopy. METHODS: A previously described four-step scale fo... περισσότερα »
Transcanal Endoscopic Management of Cerebrospinal Fluid Otorrhea Secondary to Congenital Inner Ear Malformations.
Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
Transcanal Endoscopic Management of Cerebrospinal Fluid Otorrhea Secondary to Congenital Inner Ear Malformations.: *Transcanal Endoscopic Management of Cerebrospinal Fluid Otorrhea Secondary to Congenital Inner Ear Malformations.* Otol Neurotol. 2015 Nov 4; Authors: Kou YF, Zhu VF, Kutz JW, Mitchell RB, Isaacson B Abstract OBJECTIVE: To describe the feasibility of using a transcanal endoscopic approach for management of cerebrospinal leaks secondary to congenital inner ear malformations. PATIENTS: Two pediatric patients with congenital inner ear malformations and concurrent cere...περισσότερα »
Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
Transcanal Endoscopic Management of Cerebrospinal Fluid Otorrhea Secondary to Congenital Inner Ear Malformations.: *Transcanal Endoscopic Management of Cerebrospinal Fluid Otorrhea Secondary to Congenital Inner Ear Malformations.* Otol Neurotol. 2015 Nov 4; Authors: Kou YF, Zhu VF, Kutz JW, Mitchell RB, Isaacson B Abstract OBJECTIVE: To describe the feasibility of using a transcanal endoscopic approach for management of cerebrospinal leaks secondary to congenital inner ear malformations. PATIENTS: Two pediatric patients with congenital inner ear malformations and concurrent cere...περισσότερα »
Endoscopy-assisted transoral resection of large benign parapharyngeal space tumors.
Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
Endoscopy-assisted transoral resection of large benign parapharyngeal space tumors.: [image: http:--linkinghub.elsevier.com-ihub-imag] Related Articles*Endoscopy-assisted transoral resection of large benign parapharyngeal space tumors.* Br J Oral Maxillofac Surg. 2014 Dec;52(10):970-3 Authors: Chen WL, Wang YY, Zhang DM, Huang ZQ Abstract We have evaluated the outcomes of endoscopically-assisted resection of large benign tumours of the parapharyngeal space by an intraoral approach. Six patients with primary benign tumours were treated in this way. The lesions were pleomorphic ade... περισσότερα »
Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
Endoscopy-assisted transoral resection of large benign parapharyngeal space tumors.: [image: http:--linkinghub.elsevier.com-ihub-imag] Related Articles*Endoscopy-assisted transoral resection of large benign parapharyngeal space tumors.* Br J Oral Maxillofac Surg. 2014 Dec;52(10):970-3 Authors: Chen WL, Wang YY, Zhang DM, Huang ZQ Abstract We have evaluated the outcomes of endoscopically-assisted resection of large benign tumours of the parapharyngeal space by an intraoral approach. Six patients with primary benign tumours were treated in this way. The lesions were pleomorphic ade... περισσότερα »
Importance of the chin in achieving a feminine lower face: narrowing the chin by the "mini V-line" surgery.
Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
Importance of the chin in achieving a feminine lower face: narrowing the chin by the "mini V-line" surgery.: [image: http:--pt.wkhealth.com-pt-pt-core-templa] Related Articles*Importance of the chin in achieving a feminine lower face: narrowing the chin by the "mini V-line" surgery.* J Craniofac Surg. 2014 Nov;25(6):2180-3 Authors: Lee TS, Kim HY, Kim T, Lee JH, Park S Abstract Surgery to narrow the chin is usually combined with mandible reduction, both of which may greatly improve the aesthetics of the lower face. However, some patients have a disproportionately wide chin withou... περισσότερα »
Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
Importance of the chin in achieving a feminine lower face: narrowing the chin by the "mini V-line" surgery.: [image: http:--pt.wkhealth.com-pt-pt-core-templa] Related Articles*Importance of the chin in achieving a feminine lower face: narrowing the chin by the "mini V-line" surgery.* J Craniofac Surg. 2014 Nov;25(6):2180-3 Authors: Lee TS, Kim HY, Kim T, Lee JH, Park S Abstract Surgery to narrow the chin is usually combined with mandible reduction, both of which may greatly improve the aesthetics of the lower face. However, some patients have a disproportionately wide chin withou... περισσότερα »
Nasal reconstruction with the paramedian forehead flap using the aesthetic subunits principle.
Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
Nasal reconstruction with the paramedian forehead flap using the aesthetic subunits principle.: [image: http:--pt.wkhealth.com-pt-pt-core-templa] Related Articles*Nasal reconstruction with the paramedian forehead flap using the aesthetic subunits principle.* J Craniofac Surg. 2014 Nov;25(6):2070-3 Authors: de Pochat VD, Alonso N, Ribeiro EB, Figueiredo BS, de Magaldi EN, Cunha MS, Meneses JV Abstract Reconstruction of nasal defects is challenging because it requires covering skin, supporting framework, and lining. Traditionally, the forehead flaps are transferred in 2 stages; ho... περισσότερα »
Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
Nasal reconstruction with the paramedian forehead flap using the aesthetic subunits principle.: [image: http:--pt.wkhealth.com-pt-pt-core-templa] Related Articles*Nasal reconstruction with the paramedian forehead flap using the aesthetic subunits principle.* J Craniofac Surg. 2014 Nov;25(6):2070-3 Authors: de Pochat VD, Alonso N, Ribeiro EB, Figueiredo BS, de Magaldi EN, Cunha MS, Meneses JV Abstract Reconstruction of nasal defects is challenging because it requires covering skin, supporting framework, and lining. Traditionally, the forehead flaps are transferred in 2 stages; ho... περισσότερα »
A new design of facial artery perforator flaps for the reconstruction of small- to medium-sized intraoral defects.
Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
A new design of facial artery perforator flaps for the reconstruction of small- to medium-sized intraoral defects.: [image: http:--pt.wkhealth.com-pt-pt-core-templa] Related Articles*A new design of facial artery perforator flaps for the reconstruction of small- to medium-sized intraoral defects.* J Craniofac Surg. 2014 Nov;25(6):2098-100 Authors: Du YF, Zhou WN, Li J, Jiang HB, Yuan H, Wan LZ Abstract AIM: The aim of this study was to investigate the reliability and outcomes of a new design of facial artery perforator flaps, extending from the angle of the mouth to the border of... περισσότερα »
Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
A new design of facial artery perforator flaps for the reconstruction of small- to medium-sized intraoral defects.: [image: http:--pt.wkhealth.com-pt-pt-core-templa] Related Articles*A new design of facial artery perforator flaps for the reconstruction of small- to medium-sized intraoral defects.* J Craniofac Surg. 2014 Nov;25(6):2098-100 Authors: Du YF, Zhou WN, Li J, Jiang HB, Yuan H, Wan LZ Abstract AIM: The aim of this study was to investigate the reliability and outcomes of a new design of facial artery perforator flaps, extending from the angle of the mouth to the border of... περισσότερα »
Orthognathic surgery with or without autologous fat micrograft injection: preliminary report on aesthetic outcomes and patient satisfaction.
Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
Orthognathic surgery with or without autologous fat micrograft injection: preliminary report on aesthetic outcomes and patient satisfaction.: [image: http:--linkinghub.elsevier.com-ihub-imag] Related Articles*Orthognathic surgery with or without autologous fat micrograft injection: preliminary report on aesthetic outcomes and patient satisfaction.* Int J Oral Maxillofac Surg. 2015 Mar;44(3):362-70 Authors: Raffaini M, Pisani C Abstract Orthognathic surgery leaves the intrinsic volume of the facial soft tissues untouched, sometimes resulting in unsatisfactory improvements in aesth... περισσότερα »
Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
Orthognathic surgery with or without autologous fat micrograft injection: preliminary report on aesthetic outcomes and patient satisfaction.: [image: http:--linkinghub.elsevier.com-ihub-imag] Related Articles*Orthognathic surgery with or without autologous fat micrograft injection: preliminary report on aesthetic outcomes and patient satisfaction.* Int J Oral Maxillofac Surg. 2015 Mar;44(3):362-70 Authors: Raffaini M, Pisani C Abstract Orthognathic surgery leaves the intrinsic volume of the facial soft tissues untouched, sometimes resulting in unsatisfactory improvements in aesth... περισσότερα »
Pre-operative counselling for laryngectomy patients: a systematic review.
Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
Pre-operative counselling for laryngectomy patients: a systematic review.: *Pre-operative counselling for laryngectomy patients: a systematic review.* J Laryngol Otol. 2015 Nov 16;:1-6 Authors: Fitzgerald E, Perry A Abstract OBJECTIVES: This study aimed to undertake a systematic review of the literature about pre-operative counselling for laryngectomy patients, identify its practice and patient and (where possible) carer perceptions. METHODS: A search strategy was formulated using a concept map and a Population, Intervention, Comparative Interaction and Outcomes ('PICO') schema. ...περισσότερα »
Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
Pre-operative counselling for laryngectomy patients: a systematic review.: *Pre-operative counselling for laryngectomy patients: a systematic review.* J Laryngol Otol. 2015 Nov 16;:1-6 Authors: Fitzgerald E, Perry A Abstract OBJECTIVES: This study aimed to undertake a systematic review of the literature about pre-operative counselling for laryngectomy patients, identify its practice and patient and (where possible) carer perceptions. METHODS: A search strategy was formulated using a concept map and a Population, Intervention, Comparative Interaction and Outcomes ('PICO') schema. ...περισσότερα »
Angiogenesis inhibitor; +26 new citations
Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
26 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: *Angiogenesis inhibitor* These pubmed results were generated on 2015/11/17 PubMed comprises more than 24 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites. from #PubMed 1 via ola Kala on Inoreader http://ift.tt/QGMHBq(((Angiogenesis%20inhibitor)%20AND%20%222015%2F11%2F15%2007.06%22%5BMHDA%5D%3A%222015%2F11%2F1... περισσότερα »
Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
26 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: *Angiogenesis inhibitor* These pubmed results were generated on 2015/11/17 PubMed comprises more than 24 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites. from #PubMed 1 via ola Kala on Inoreader http://ift.tt/QGMHBq(((Angiogenesis%20inhibitor)%20AND%20%222015%2F11%2F15%2007.06%22%5BMHDA%5D%3A%222015%2F11%2F1... περισσότερα »
Knowledge, attitudes, beliefs and practices related to chronic suppurative otitis media and hearing impairment in Pokhara, Nepal.
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 1 ώρα
Knowledge, attitudes, beliefs and practices related to chronic suppurative otitis media and hearing impairment in Pokhara, Nepal.: *Knowledge, attitudes, beliefs and practices related to chronic suppurative otitis media and hearing impairment in Pokhara, Nepal.* J Laryngol Otol. 2015 Nov 16;:1-10 Authors: Poole NF, Skilton MK, Martin TC, Smith MC Abstract BACKGROUND: Nepal has a high prevalence of chronic suppurative otitis media and hearing impairment. An improved understanding of patients' knowledge, attitudes, beliefs and practices is therefore important for effective healthca...περισσότερα »
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 1 ώρα
Knowledge, attitudes, beliefs and practices related to chronic suppurative otitis media and hearing impairment in Pokhara, Nepal.: *Knowledge, attitudes, beliefs and practices related to chronic suppurative otitis media and hearing impairment in Pokhara, Nepal.* J Laryngol Otol. 2015 Nov 16;:1-10 Authors: Poole NF, Skilton MK, Martin TC, Smith MC Abstract BACKGROUND: Nepal has a high prevalence of chronic suppurative otitis media and hearing impairment. An improved understanding of patients' knowledge, attitudes, beliefs and practices is therefore important for effective healthca...περισσότερα »
Obliquity of the stapes in otosclerosis: intra-operative observations and implications in stapes surgery.
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 1 ώρα
Obliquity of the stapes in otosclerosis: intra-operative observations and implications in stapes surgery.: *Obliquity of the stapes in otosclerosis: intra-operative observations and implications in stapes surgery.* J Laryngol Otol. 2015 Nov 16;:1-11 Authors: Anand V, Udayabhanu HN Abstract OBJECTIVE: To establish the prevalence of stapes obliquity as observed in otosclerosis patients during stapes surgery by a simple method of intra-operative measurement. DESIGN: Prospective observational study. RESULTS: Intra-operative measurements showed that the mean distance (± standard dev...περισσότερα »
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 1 ώρα
Obliquity of the stapes in otosclerosis: intra-operative observations and implications in stapes surgery.: *Obliquity of the stapes in otosclerosis: intra-operative observations and implications in stapes surgery.* J Laryngol Otol. 2015 Nov 16;:1-11 Authors: Anand V, Udayabhanu HN Abstract OBJECTIVE: To establish the prevalence of stapes obliquity as observed in otosclerosis patients during stapes surgery by a simple method of intra-operative measurement. DESIGN: Prospective observational study. RESULTS: Intra-operative measurements showed that the mean distance (± standard dev...περισσότερα »
Subannular tube insertion: anatomical considerations.
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 1 ώρα
Subannular tube insertion: anatomical considerations.: *Subannular tube insertion: anatomical considerations.* J Laryngol Otol. 2015 Nov 16;:1-7 Authors: Guidera AK, Benoiton L, McManus L, Dawes PJ Abstract OBJECTIVES: To assess the distance between the bony groove created during subannular tubes placement and the chorda tympani, and examine the depth of the hypotympanum and retrotympanum. METHOD: Grooves drilled in cadaver temporal bones at two levels were imaged to measure: the distance between the chorda tympani nerve and the tympanic sulcus, and the depth of the hypotympanum ... περισσότερα »
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 1 ώρα
Subannular tube insertion: anatomical considerations.: *Subannular tube insertion: anatomical considerations.* J Laryngol Otol. 2015 Nov 16;:1-7 Authors: Guidera AK, Benoiton L, McManus L, Dawes PJ Abstract OBJECTIVES: To assess the distance between the bony groove created during subannular tubes placement and the chorda tympani, and examine the depth of the hypotympanum and retrotympanum. METHOD: Grooves drilled in cadaver temporal bones at two levels were imaged to measure: the distance between the chorda tympani nerve and the tympanic sulcus, and the depth of the hypotympanum ... περισσότερα »
Computerized tomography based tumor-thickness measurement is useful to predict postoperative pathological tumor thickness in oral tongue squamous cell carcinoma
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 1 ώρα
Computerized tomography based tumor-thickness measurement is useful to predict postoperative pathological tumor thickness in oral tongue squamous cell carcinoma: Abstract BackgroundTumor thickness has been shown in oral tongue squamous cell carcinoma (OTSCC) to be a predictor of cervical metastasis. The postoperative histological measurement is certainly the most accurate, but it would be of clinical interest to gain this information prior to treatment planning. This retrospective study aimed to compare the tumor thickness measurement between preoperative, CT scan, and surgical sp...περισσότερα »
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 1 ώρα
Computerized tomography based tumor-thickness measurement is useful to predict postoperative pathological tumor thickness in oral tongue squamous cell carcinoma: Abstract BackgroundTumor thickness has been shown in oral tongue squamous cell carcinoma (OTSCC) to be a predictor of cervical metastasis. The postoperative histological measurement is certainly the most accurate, but it would be of clinical interest to gain this information prior to treatment planning. This retrospective study aimed to compare the tumor thickness measurement between preoperative, CT scan, and surgical sp...περισσότερα »
Objectifying “Pain” in the Modern Neurosciences
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 1 ώρα
Brain Sciences, Vol. 5, Pages 521-545: Objectifying “Pain” in the Modern Neurosciences: A Historical Account of the Visualization Technologies Used in the Development of an “Algesiogenic Pathology”, 1850 to 2000: Particularly with the fundamental works of the Leipzig school of experimental psychophysiology (between the 1850s and 1880s), the modern neurosciences witnessed an increasing interest in attempts to objectify “pain” as a bodily signal and physiological value. This development has led to refined psychological test repertoires and new clinical measurement techniques, which be...περισσότερα »
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 1 ώρα
Brain Sciences, Vol. 5, Pages 521-545: Objectifying “Pain” in the Modern Neurosciences: A Historical Account of the Visualization Technologies Used in the Development of an “Algesiogenic Pathology”, 1850 to 2000: Particularly with the fundamental works of the Leipzig school of experimental psychophysiology (between the 1850s and 1880s), the modern neurosciences witnessed an increasing interest in attempts to objectify “pain” as a bodily signal and physiological value. This development has led to refined psychological test repertoires and new clinical measurement techniques, which be...περισσότερα »
Palliative enteral feeding for patients with malignant esophageal obstruction: a retrospective study
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 1 ώρα
Palliative enteral feeding for patients with malignant esophageal obstruction: a retrospective study: This study aimed to compare the clinical outcomes of enteral tube feeding and esophageal stenting for patients with malignant esophageal obstruction and a short life expectancy. Methods: Thirty-one patients were divided into 3 groups according to their treatment modality: NG tube (n = 12), esophageal stent group (n = 10), and supportive care with nil per os (NPO) (n = 9). Enteral nutrition, clinical outcomes, length of hospital stay, and median survival were evaluated. Results: There ... περισσότερα »
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 1 ώρα
Palliative enteral feeding for patients with malignant esophageal obstruction: a retrospective study: This study aimed to compare the clinical outcomes of enteral tube feeding and esophageal stenting for patients with malignant esophageal obstruction and a short life expectancy. Methods: Thirty-one patients were divided into 3 groups according to their treatment modality: NG tube (n = 12), esophageal stent group (n = 10), and supportive care with nil per os (NPO) (n = 9). Enteral nutrition, clinical outcomes, length of hospital stay, and median survival were evaluated. Results: There ... περισσότερα »
Comparison of the anti-inflammatory effect of dexamethasone and ketorolac in the extractions of third molars
Alexandros G. SfakianakisστοΚοσμητική ΟδοντοΙατρική και ΓναθοΧειρουργικήΠριν από 1 ώρα
Comparison of the anti-inflammatory effect of dexamethasone and ketorolac in the extractions of third molars: AbstractThis double-blind, split-mouth, and randomized study was aimed to compare the efficacy of dexamethasone and ketorolac tromethamine, through the evaluation of pain, edema, and limitation of mouth opening. Thirty-four individuals aged 18–26 years, having bilateral mandibular third molars, in a similar position, were selected. Two different surgical procedures were performed on the same individual by the single surgeon. For an extraction, the individual received 1 caps... περισσότερα »
Alexandros G. SfakianakisστοΚοσμητική ΟδοντοΙατρική και ΓναθοΧειρουργικήΠριν από 1 ώρα
Comparison of the anti-inflammatory effect of dexamethasone and ketorolac in the extractions of third molars: AbstractThis double-blind, split-mouth, and randomized study was aimed to compare the efficacy of dexamethasone and ketorolac tromethamine, through the evaluation of pain, edema, and limitation of mouth opening. Thirty-four individuals aged 18–26 years, having bilateral mandibular third molars, in a similar position, were selected. Two different surgical procedures were performed on the same individual by the single surgeon. For an extraction, the individual received 1 caps... περισσότερα »
Electrical enhancement of chlorhexidine efficacy against the periodontal pathogen Porphyromonas gingivalis within a biofilm.
Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
*Electrical enhancement of chlorhexidine efficacy against the periodontal pathogen Porphyromonas gingivalis within a biofilm.* New Microbiol. 2015 Nov;38(4):511-519 Authors: Lasserre JF, Leprince JG, Toma S, Brecx MC Abstract Electric currents have been shown to promote the antimicrobial effectiveness of several biocides against microbial biofilms. Therefore, the objective of this work was to test the null hypothesis that low electric direct currents (DC) do not influence chlorhexidine (CHX) efficacy against the periodontal pathogen Porphyromonas gingivalis within a biofilm. A b... περισσότερα »
Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
*Electrical enhancement of chlorhexidine efficacy against the periodontal pathogen Porphyromonas gingivalis within a biofilm.* New Microbiol. 2015 Nov;38(4):511-519 Authors: Lasserre JF, Leprince JG, Toma S, Brecx MC Abstract Electric currents have been shown to promote the antimicrobial effectiveness of several biocides against microbial biofilms. Therefore, the objective of this work was to test the null hypothesis that low electric direct currents (DC) do not influence chlorhexidine (CHX) efficacy against the periodontal pathogen Porphyromonas gingivalis within a biofilm. A b... περισσότερα »
An update on integrase inhibitors: new opportunities for a personalized therapy? The NEXTaim Project.
Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
*An update on integrase inhibitors: new opportunities for a personalized therapy? The NEXTaim Project.* New Microbiol. 2015 Nov;38(4):443-490 Authors: Andreoni M, Marcotullio S, Puro V, De Carli G, Tambussi G, Nozza S, Gori A, Rusconi S, Santoro MM, Clementi M, Perno CF, d'Arminio Monforte A, Maggiolo F, Castagna A, De Luca A, Galli M, Giacomelli A, Borderi M, Guaraldi G, Calcagno A, Di Perri G, Bonora S, Mussini C, Di Biagio A, Puoti M, Bruno R, Zuccaro V, Antinori A, Cinque P, Croce D, Restelli U, Rizzardini G, Lazzarin A Abstract Thanks to the development of antiretroviral ag...περισσότερα »
Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
*An update on integrase inhibitors: new opportunities for a personalized therapy? The NEXTaim Project.* New Microbiol. 2015 Nov;38(4):443-490 Authors: Andreoni M, Marcotullio S, Puro V, De Carli G, Tambussi G, Nozza S, Gori A, Rusconi S, Santoro MM, Clementi M, Perno CF, d'Arminio Monforte A, Maggiolo F, Castagna A, De Luca A, Galli M, Giacomelli A, Borderi M, Guaraldi G, Calcagno A, Di Perri G, Bonora S, Mussini C, Di Biagio A, Puoti M, Bruno R, Zuccaro V, Antinori A, Cinque P, Croce D, Restelli U, Rizzardini G, Lazzarin A Abstract Thanks to the development of antiretroviral ag...περισσότερα »
Quantitative Real-Time Quaking-Induced Conversion Allows Monitoring of Disease-Modifying Therapy in the Urine of Prion-Infected Mice.
Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
[image: http:--pt.wkhealth.com-pt-pt-core-templa] Related Articles *Quantitative Real-Time Quaking-Induced Conversion Allows Monitoring of Disease-Modifying Therapy in the Urine of Prion-Infected Mice.* J Neuropathol Exp Neurol. 2015 Sep;74(9):924-33 Authors: Shi S, Wagner J, Mitteregger-Kretzschmar G, Ryazanov S, Leonov A, Griesinger C, Giese A Abstract Prion diseases are fatal neurodegenerative diseases characterized by accumulation of the pathogenic prion protein PrP in the brain. We established quantitative real-time quaking-induced conversion for the measurement of minute am...περισσότερα »
Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
[image: http:--pt.wkhealth.com-pt-pt-core-templa] Related Articles *Quantitative Real-Time Quaking-Induced Conversion Allows Monitoring of Disease-Modifying Therapy in the Urine of Prion-Infected Mice.* J Neuropathol Exp Neurol. 2015 Sep;74(9):924-33 Authors: Shi S, Wagner J, Mitteregger-Kretzschmar G, Ryazanov S, Leonov A, Griesinger C, Giese A Abstract Prion diseases are fatal neurodegenerative diseases characterized by accumulation of the pathogenic prion protein PrP in the brain. We established quantitative real-time quaking-induced conversion for the measurement of minute am...περισσότερα »
BRAF Fusion Analysis in Pilocytic Astrocytomas: KIAA1549-BRAF 15-9 Fusions Are More Frequent in the Midline Than Within the Cerebellum.
Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
[image: http:--pt.wkhealth.com-pt-pt-core-templa] [image: http:--http://ift.tt/1Fkw4zC] Related Articles *BRAF Fusion Analysis in Pilocytic Astrocytomas: KIAA1549-BRAF 15-9 Fusions Are More Frequent in the Midline Than Within the Cerebellum.* J Neuropathol Exp Neurol. 2015 Sep;74(9):867-72 Authors: Faulkner C, Ellis HP, Shaw A, Penman C, Palmer A, Wragg C, Greenslade M, Haynes HR, Williams H, Lowis S, White P, Williams M, Capper D, Kurian KM Abstract Pilocytic astrocytomas (PAs) are increasingly tested for KIAA1549-BRAF fusions. We used reverse transcription polymerase chain reac... περισσότερα »
Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
[image: http:--pt.wkhealth.com-pt-pt-core-templa] [image: http:--http://ift.tt/1Fkw4zC] Related Articles *BRAF Fusion Analysis in Pilocytic Astrocytomas: KIAA1549-BRAF 15-9 Fusions Are More Frequent in the Midline Than Within the Cerebellum.* J Neuropathol Exp Neurol. 2015 Sep;74(9):867-72 Authors: Faulkner C, Ellis HP, Shaw A, Penman C, Palmer A, Wragg C, Greenslade M, Haynes HR, Williams H, Lowis S, White P, Williams M, Capper D, Kurian KM Abstract Pilocytic astrocytomas (PAs) are increasingly tested for KIAA1549-BRAF fusions. We used reverse transcription polymerase chain reac... περισσότερα »
New prognostic score for the prediction of 30-day outcome in spontaneous supratentorial cerebral haemorrhage.
Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
[image: http:--images.hindawi.com-linkout-hindaw] [image: http:--http://ift.tt/1Fkw4zC] Related Articles *New prognostic score for the prediction of 30-day outcome in spontaneous supratentorial cerebral haemorrhage.* Biomed Res Int. 2015;2015:961085 Authors: Szepesi R, Széll IK, Hortobágyi T, Kardos L, Nagy K, Lánczi LI, Berényi E, Bereczki D, Csiba L Abstract AIMS: The purpose of the present study was to evaluate predictors of outcome in primary supratentorial cerebral haemorrhage. Furthermore, we aimed to develop a prognostic model to predict 30-day fatality. METHODS: We retros...περισσότερα »
Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
[image: http:--images.hindawi.com-linkout-hindaw] [image: http:--http://ift.tt/1Fkw4zC] Related Articles *New prognostic score for the prediction of 30-day outcome in spontaneous supratentorial cerebral haemorrhage.* Biomed Res Int. 2015;2015:961085 Authors: Szepesi R, Széll IK, Hortobágyi T, Kardos L, Nagy K, Lánczi LI, Berényi E, Bereczki D, Csiba L Abstract AIMS: The purpose of the present study was to evaluate predictors of outcome in primary supratentorial cerebral haemorrhage. Furthermore, we aimed to develop a prognostic model to predict 30-day fatality. METHODS: We retros...περισσότερα »
Thyroid Hormone Stimulation of Autophagy Is Essential for Mitochondrial Biogenesis and Activity in Skeletal Muscle
Alexandros G. SfakianakisστοΕνδοκρινολογίαΠριν από 1 ώρα
Endocrinology, Early Release. from Endocrinology via ola Kala on Inoreader http://ift.tt/1SNwnfz via IFTTT
Alexandros G. SfakianakisστοΕνδοκρινολογίαΠριν από 1 ώρα
Endocrinology, Early Release. from Endocrinology via ola Kala on Inoreader http://ift.tt/1SNwnfz via IFTTT
ANDROGEN DEFICIENCY EXACERBATES HIGH FAT DIET-INDUCED METABOLIC ALTERATIONS IN MALE MICE
Alexandros G. SfakianakisστοΕνδοκρινολογίαΠριν από 1 ώρα
Endocrinology, Early Release. from Endocrinology via ola Kala on Inoreader http://ift.tt/1ktH7UX via IFTTT
Alexandros G. SfakianakisστοΕνδοκρινολογίαΠριν από 1 ώρα
Endocrinology, Early Release. from Endocrinology via ola Kala on Inoreader http://ift.tt/1ktH7UX via IFTTT
Both estrogen and androgen modify the response to activation of neurokinin-3 and κ-opioid receptors in arcuate kisspeptin neurons from male mice
Alexandros G. SfakianakisστοΕνδοκρινολογίαΠριν από 1 ώρα
Endocrinology, Early Release. from Endocrinology via ola Kala on Inoreader http://ift.tt/1ktH4Zp via IFTTT
Alexandros G. SfakianakisστοΕνδοκρινολογίαΠριν από 1 ώρα
Endocrinology, Early Release. from Endocrinology via ola Kala on Inoreader http://ift.tt/1ktH4Zp via IFTTT
GnRH episodic secretion is altered by pharmacological blockade of gap junctions: possible involvement of Glial cells
Alexandros G. SfakianakisστοΕνδοκρινολογίαΠριν από 1 ώρα
Endocrinology, Early Release. from Endocrinology via ola Kala on Inoreader http://ift.tt/1SNwk3l via IFTTT
Alexandros G. SfakianakisστοΕνδοκρινολογίαΠριν από 1 ώρα
Endocrinology, Early Release. from Endocrinology via ola Kala on Inoreader http://ift.tt/1SNwk3l via IFTTT
Conditional Deletion of Prolyl Hydroxylase Domain-containing Protein 2 (Phd2) Gene Reveals its Essential Role in Chondrocyte Function and Endochondral Bone Formation
Alexandros G. SfakianakisστοΕνδοκρινολογίαΠριν από 1 ώρα
Endocrinology, Early Release. from Endocrinology via ola Kala on Inoreader http://ift.tt/1SNwk3d via IFTTT
Alexandros G. SfakianakisστοΕνδοκρινολογίαΠριν από 1 ώρα
Endocrinology, Early Release. from Endocrinology via ola Kala on Inoreader http://ift.tt/1SNwk3d via IFTTT
Down, But Not Out: Partial Elimination of Androgen Receptors in the Male Mouse Brain Does Not Affect Androgenic Regulation of Anxiety or HPA Activity
Alexandros G. SfakianakisστοΕνδοκρινολογίαΠριν από 1 ώρα
Endocrinology, Early Release. from Endocrinology via ola Kala on Inoreader http://ift.tt/1MrOIu4 via IFTTT
Alexandros G. SfakianakisστοΕνδοκρινολογίαΠριν από 1 ώρα
Endocrinology, Early Release. from Endocrinology via ola Kala on Inoreader http://ift.tt/1MrOIu4 via IFTTT
XBP1 Regulates the Biosynthetic Capacity of the Mammary Gland During Lactation by Controlling Epithelial Expansion and Endoplasmic Reticulum Formation
Alexandros G. SfakianakisστοΕνδοκρινολογίαΠριν από 1 ώρα
Endocrinology, Early Release. from Endocrinology via ola Kala on Inoreader http://ift.tt/1SowNbg via IFTTT
Alexandros G. SfakianakisστοΕνδοκρινολογίαΠριν από 1 ώρα
Endocrinology, Early Release. from Endocrinology via ola Kala on Inoreader http://ift.tt/1SowNbg via IFTTT
Binding Selectivity of Abaloparatide for PTH-type-1-Receptor Conformations and Effects on Downstream Signaling
Alexandros G. SfakianakisστοΕνδοκρινολογίαΠριν από 1 ώρα
Endocrinology, Early Release. from Endocrinology via ola Kala on Inoreader http://ift.tt/1iYIycs via IFTTT
Alexandros G. SfakianakisστοΕνδοκρινολογίαΠριν από 1 ώρα
Endocrinology, Early Release. from Endocrinology via ola Kala on Inoreader http://ift.tt/1iYIycs via IFTTT
Massively parallel sequencing of Phyllodes tumours of the breast reveals actionable mutations, and TERT promoter hotspot mutations and TERT gene amplification as likely drivers of progression
Alexandros G. SfakianakisστοΠαθολοΑνατομίαΠριν από 1 ώρα
[image: cover.gif?v=1&s=db129dfe073b014dc61a98d5] Abstract Phyllodes tumours (PTs) are breast fibroepithelial lesions that are graded based on histological criteria as benign, borderline or malignant. PTs may recur locally. Borderline PTs and malignant PTs may metastasize to distant sites. Breast fibroepithelial lesions, including PTs and fibroadenomas, are characterized by recurrent *MED12* exon 2 somatic mutations. We sought to define the repertoire of somatic genetic alterations in PTs and whether these may assist in the differential diagnosis of these lesions. We collected 10...περισσότερα »
Alexandros G. SfakianakisστοΠαθολοΑνατομίαΠριν από 1 ώρα
[image: cover.gif?v=1&s=db129dfe073b014dc61a98d5] Abstract Phyllodes tumours (PTs) are breast fibroepithelial lesions that are graded based on histological criteria as benign, borderline or malignant. PTs may recur locally. Borderline PTs and malignant PTs may metastasize to distant sites. Breast fibroepithelial lesions, including PTs and fibroadenomas, are characterized by recurrent *MED12* exon 2 somatic mutations. We sought to define the repertoire of somatic genetic alterations in PTs and whether these may assist in the differential diagnosis of these lesions. We collected 10...περισσότερα »
Efficacy of gabapentin enacarbil in adult patients with severe primary restless legs syndrome
Alexandros G. SfakianakisστοΥπνική Άπνοια και Διαταραχές ΎπνουΠριν από 1 ώρα
Publication date: Available online 14 November 2015 *Source:*Sleep Medicine Author(s): Daniel O. Lee, Mark J. Buchfuhrer, Diego Garcia-Borreguero, Alon Y. Avidan, Mansoor Ahmed, Ryan Hays, William G. Ondo, Mark J. Jaros, Richard Kim, Gwendoline Shang ObjectivesAssess efficacy and tolerability of gabapentin enacarbil (GEn) in adults with severe primary restless legs syndrome (RLS).MethodsWe pooled data from three 12-week, double-blind, placebo-controlled, randomized trials (NCT00298623, NCT00365352, NCT01332305) across GEn 600-mg, GEn 1200-mg, and placebo treatment groups for severe ... περισσότερα »
Alexandros G. SfakianakisστοΥπνική Άπνοια και Διαταραχές ΎπνουΠριν από 1 ώρα
Publication date: Available online 14 November 2015 *Source:*Sleep Medicine Author(s): Daniel O. Lee, Mark J. Buchfuhrer, Diego Garcia-Borreguero, Alon Y. Avidan, Mansoor Ahmed, Ryan Hays, William G. Ondo, Mark J. Jaros, Richard Kim, Gwendoline Shang ObjectivesAssess efficacy and tolerability of gabapentin enacarbil (GEn) in adults with severe primary restless legs syndrome (RLS).MethodsWe pooled data from three 12-week, double-blind, placebo-controlled, randomized trials (NCT00298623, NCT00365352, NCT01332305) across GEn 600-mg, GEn 1200-mg, and placebo treatment groups for severe ... περισσότερα »
Relations between psychophysical measures of spatial hearing and self-reported spatial-hearing abilities.
Alexandros G. SfakianakisστοHead and NeckΠριν από 2 ώρες
[image: http:--http://ift.tt/1XLQsFQ] Related Articles *Relations between psychophysical measures of spatial hearing and self-reported spatial-hearing abilities.* Int J Audiol. 2015 Mar;54(3):182-9 Authors: Van Esch TE, Lutman ME, Vormann M, Lyzenga J, Hällgren M, Larsby B, Athalye SP, Houtgast T, Kollmeier B, Dreschler WA Abstract OBJECTIVE: The aim of the present study was to investigate how well the virtual psychophysical measures of spatial hearing from the preliminary auditory profile predict self-reported spatial-hearing abilities. DESIGN: Virtual spatial-hearings tests (con... περισσότερα »
Alexandros G. SfakianakisστοHead and NeckΠριν από 2 ώρες
[image: http:--http://ift.tt/1XLQsFQ] Related Articles *Relations between psychophysical measures of spatial hearing and self-reported spatial-hearing abilities.* Int J Audiol. 2015 Mar;54(3):182-9 Authors: Van Esch TE, Lutman ME, Vormann M, Lyzenga J, Hällgren M, Larsby B, Athalye SP, Houtgast T, Kollmeier B, Dreschler WA Abstract OBJECTIVE: The aim of the present study was to investigate how well the virtual psychophysical measures of spatial hearing from the preliminary auditory profile predict self-reported spatial-hearing abilities. DESIGN: Virtual spatial-hearings tests (con... περισσότερα »
Statistical Voxel-Based Methods and [18F]FDG PET Brain Imaging: Frontiers for the Diagnosis of AD.
Alexandros G. SfakianakisστοHead and NeckΠριν από 2 ώρες
*Statistical Voxel-Based Methods and [18F]FDG PET Brain Imaging: Frontiers for the Diagnosis of AD.* Curr Alzheimer Res. 2015 Nov 16; Authors: Gallivanone F, Rosa PA, Castiglioni I Abstract Recommended guidelines for the diagnosis of dementia due to Alzheimer's Disease (AD) were revised in recent years, including Positron Emission Tomography (PET) as an in-vivo diagnostic imaging technique for the diagnosis of neurodegeneration. In particular PET, using 18F-fluorodeoxiglucouse ([18F]FDG), is able to detect very early changes of glucose consumption at the synaptic level, enabling... περισσότερα »
Alexandros G. SfakianakisστοHead and NeckΠριν από 2 ώρες
*Statistical Voxel-Based Methods and [18F]FDG PET Brain Imaging: Frontiers for the Diagnosis of AD.* Curr Alzheimer Res. 2015 Nov 16; Authors: Gallivanone F, Rosa PA, Castiglioni I Abstract Recommended guidelines for the diagnosis of dementia due to Alzheimer's Disease (AD) were revised in recent years, including Positron Emission Tomography (PET) as an in-vivo diagnostic imaging technique for the diagnosis of neurodegeneration. In particular PET, using 18F-fluorodeoxiglucouse ([18F]FDG), is able to detect very early changes of glucose consumption at the synaptic level, enabling... περισσότερα »
Thyroid Gland Malignancies.
Alexandros G. SfakianakisστοHead and NeckΠριν από 2 ώρες
*Thyroid Gland Malignancies.* Hematol Oncol Clin North Am. 2015 Dec;29(6):1123-43 Authors: Cabanillas ME, Dadu R, Hu MI, Lu C, Gunn GB, Grubbs EG, Lai SY, Williams MD Abstract Surgery remains the most important effective treatment for differentiated (DTC) and medullary thyroid cancer (MTC). Radioactive iodine (RAI) is another important treatment but is reserved only for DTC whose disease captures RAI. Once patients fail primary therapy, observation is often recommended, as most DTC and MTC patients will have indolent disease. However, in a fraction of patients, systemic therapy ...περισσότερα »
Alexandros G. SfakianakisστοHead and NeckΠριν από 2 ώρες
*Thyroid Gland Malignancies.* Hematol Oncol Clin North Am. 2015 Dec;29(6):1123-43 Authors: Cabanillas ME, Dadu R, Hu MI, Lu C, Gunn GB, Grubbs EG, Lai SY, Williams MD Abstract Surgery remains the most important effective treatment for differentiated (DTC) and medullary thyroid cancer (MTC). Radioactive iodine (RAI) is another important treatment but is reserved only for DTC whose disease captures RAI. Once patients fail primary therapy, observation is often recommended, as most DTC and MTC patients will have indolent disease. However, in a fraction of patients, systemic therapy ...περισσότερα »
An updated systematic review of lung chemo-radiotherapy using a new evidence aggregation method.
Alexandros G. SfakianakisστοHead and NeckΠριν από 2 ώρες
[image: http:--linkinghub.elsevier.com-ihub-imag] Related Articles *An updated systematic review of lung chemo-radiotherapy using a new evidence aggregation method.* Lung Cancer. 2015 Mar;87(3):290-5 Authors: Williams M, Liu ZW, Hunter A, Macbeth F Abstract OBJECTIVE: The main treatment for locally-advanced, unresectable non-small cell lung cancer (NSCLC) is radical radiotherapy, with or without chemotherapy. Numerous trials have been performed, the results of which often disagree. Despite publication of several systematic reviews, there is not a consensus on practice, and outcom...περισσότερα »
Alexandros G. SfakianakisστοHead and NeckΠριν από 2 ώρες
[image: http:--linkinghub.elsevier.com-ihub-imag] Related Articles *An updated systematic review of lung chemo-radiotherapy using a new evidence aggregation method.* Lung Cancer. 2015 Mar;87(3):290-5 Authors: Williams M, Liu ZW, Hunter A, Macbeth F Abstract OBJECTIVE: The main treatment for locally-advanced, unresectable non-small cell lung cancer (NSCLC) is radical radiotherapy, with or without chemotherapy. Numerous trials have been performed, the results of which often disagree. Despite publication of several systematic reviews, there is not a consensus on practice, and outcom...περισσότερα »
Scintigraphic Identification of Gastric Tissue in a Mediastinal Mass.
Alexandros G. SfakianakisστοHead and NeckΠριν από 2 ώρες
*Scintigraphic Identification of Gastric Tissue in a Mediastinal Mass.* Clin Nucl Med. 2015 Nov 13; Authors: Mainta IC, Montet X, Willi JP, Dulguerov P, Rager O Abstract We present a Tc pertechnetate scintigraphy performed in a 64-year-old woman to investigate a mediastinal cystic mass in search of residual gastric mucosa after gastrectomy. She had a history of esophagectomy and gastric pull-up for esophageal cancer. Postoperative leakage necessitated ablation of the gastric pull-up and reconstruction using part of the colon. Oral realimentation resulted in mediastinal pain and b... περισσότερα »
Alexandros G. SfakianakisστοHead and NeckΠριν από 2 ώρες
*Scintigraphic Identification of Gastric Tissue in a Mediastinal Mass.* Clin Nucl Med. 2015 Nov 13; Authors: Mainta IC, Montet X, Willi JP, Dulguerov P, Rager O Abstract We present a Tc pertechnetate scintigraphy performed in a 64-year-old woman to investigate a mediastinal cystic mass in search of residual gastric mucosa after gastrectomy. She had a history of esophagectomy and gastric pull-up for esophageal cancer. Postoperative leakage necessitated ablation of the gastric pull-up and reconstruction using part of the colon. Oral realimentation resulted in mediastinal pain and b... περισσότερα »
Transcanal Endoscopic Management of Cerebrospinal Fluid Otorrhea Secondary to Congenital Inner Ear Malformations.
Alexandros G. SfakianakisστοHead and NeckΠριν από 2 ώρες
*Transcanal Endoscopic Management of Cerebrospinal Fluid Otorrhea Secondary to Congenital Inner Ear Malformations.* Otol Neurotol. 2015 Nov 4; Authors: Kou YF, Zhu VF, Kutz JW, Mitchell RB, Isaacson B Abstract OBJECTIVE: To describe the feasibility of using a transcanal endoscopic approach for management of cerebrospinal leaks secondary to congenital inner ear malformations. PATIENTS: Two pediatric patients with congenital inner ear malformations and concurrent cerebrospinal fluid leakage. INTERVENTION: A stapedectomy was performed and the inner ear was packed with temporalis mus... περισσότερα »
Alexandros G. SfakianakisστοHead and NeckΠριν από 2 ώρες
*Transcanal Endoscopic Management of Cerebrospinal Fluid Otorrhea Secondary to Congenital Inner Ear Malformations.* Otol Neurotol. 2015 Nov 4; Authors: Kou YF, Zhu VF, Kutz JW, Mitchell RB, Isaacson B Abstract OBJECTIVE: To describe the feasibility of using a transcanal endoscopic approach for management of cerebrospinal leaks secondary to congenital inner ear malformations. PATIENTS: Two pediatric patients with congenital inner ear malformations and concurrent cerebrospinal fluid leakage. INTERVENTION: A stapedectomy was performed and the inner ear was packed with temporalis mus... περισσότερα »
Histopathologic Findings in Peripheral Vestibular System From Patients With Systemic Lupus Erythematosus: A Human Temporal Bone Study.
Alexandros G. SfakianakisστοHead and NeckΠριν από 2 ώρες
*Histopathologic Findings in Peripheral Vestibular System From Patients With Systemic Lupus Erythematosus: A Human Temporal Bone Study.* Otol Neurotol. 2015 Nov 4; Authors: Kariya S, Hzl Ö, Kaya S, Hzl P, Nishizaki K, Paparella MM, Cureoglu S Abstract HYPOTHESIS: We hypothesized that a pathologic condition exists in vestibular hair cells in human temporal bones from patients with systemic lupus erythematosus (SLE). BACKGROUND: A significant association between sensorineural hearing loss and autoimmune disease has been reported. Patients with SLE also frequently have vestibular s... περισσότερα »
Alexandros G. SfakianakisστοHead and NeckΠριν από 2 ώρες
*Histopathologic Findings in Peripheral Vestibular System From Patients With Systemic Lupus Erythematosus: A Human Temporal Bone Study.* Otol Neurotol. 2015 Nov 4; Authors: Kariya S, Hzl Ö, Kaya S, Hzl P, Nishizaki K, Paparella MM, Cureoglu S Abstract HYPOTHESIS: We hypothesized that a pathologic condition exists in vestibular hair cells in human temporal bones from patients with systemic lupus erythematosus (SLE). BACKGROUND: A significant association between sensorineural hearing loss and autoimmune disease has been reported. Patients with SLE also frequently have vestibular s... περισσότερα »
Teratoma of the Middle Ear With Cholesteatoma.
Alexandros G. SfakianakisστοHead and NeckΠριν από 2 ώρες
*Teratoma of the Middle Ear With Cholesteatoma.* Otol Neurotol. 2015 Nov 4; Authors: Wang J, Gong S, Li X PMID: 26571407 [PubMed - as supplied by publisher] from #PubMed 1 via ola Kala on Inoreader http://ift.tt/1j4ZG0d via IFTTT
Alexandros G. SfakianakisστοHead and NeckΠριν από 2 ώρες
*Teratoma of the Middle Ear With Cholesteatoma.* Otol Neurotol. 2015 Nov 4; Authors: Wang J, Gong S, Li X PMID: 26571407 [PubMed - as supplied by publisher] from #PubMed 1 via ola Kala on Inoreader http://ift.tt/1j4ZG0d via IFTTT
Can High-Resolution Computed Tomography Detect a Therapeutic Response to Medical Treatment in a Patient With Otosclerosis?
Alexandros G. SfakianakisστοHead and NeckΠριν από 2 ώρες
*Can High-Resolution Computed Tomography Detect a Therapeutic Response to Medical Treatment in a Patient With Otosclerosis?* Otol Neurotol. 2015 Nov 4; Authors: Jung ME, WippoldII FJ, Goebel JA PMID: 26571406 [PubMed - as supplied by publisher] from #PubMed 1 via ola Kala on Inoreader http://ift.tt/1j4ZE8B via IFTTT
Alexandros G. SfakianakisστοHead and NeckΠριν από 2 ώρες
*Can High-Resolution Computed Tomography Detect a Therapeutic Response to Medical Treatment in a Patient With Otosclerosis?* Otol Neurotol. 2015 Nov 4; Authors: Jung ME, WippoldII FJ, Goebel JA PMID: 26571406 [PubMed - as supplied by publisher] from #PubMed 1 via ola Kala on Inoreader http://ift.tt/1j4ZE8B via IFTTT
An analysis of early oncologic head and neck free flap reoperations from the 2005-2012 ACS-NSQIP dataset.
Alexandros G. SfakianakisστοHead and NeckΠριν από 2 ώρες
*An analysis of early oncologic head and neck free flap reoperations from the 2005-2012 ACS-NSQIP dataset.* J Plast Surg Hand Surg. 2015 Nov 16;:1-8 Authors: Ligh CA, Nelson JA, Wink JD, Gerety PA, Fischer JP, Wu LC, Kanchwala SK Abstract BACKGROUND: There are limited population-based studies that examine perioperative factors that influence postoperative surgical take-backs to the OR following free flap (FF) reconstruction for head/neck cancer extirpation. The purpose of this study was to critically analyse head/neck free flaps (HNFF) captured in the ACS-NSQIP dataset with a sp...περισσότερα »
Alexandros G. SfakianakisστοHead and NeckΠριν από 2 ώρες
*An analysis of early oncologic head and neck free flap reoperations from the 2005-2012 ACS-NSQIP dataset.* J Plast Surg Hand Surg. 2015 Nov 16;:1-8 Authors: Ligh CA, Nelson JA, Wink JD, Gerety PA, Fischer JP, Wu LC, Kanchwala SK Abstract BACKGROUND: There are limited population-based studies that examine perioperative factors that influence postoperative surgical take-backs to the OR following free flap (FF) reconstruction for head/neck cancer extirpation. The purpose of this study was to critically analyse head/neck free flaps (HNFF) captured in the ACS-NSQIP dataset with a sp...περισσότερα »
Vestibular Schwannoma: The Evolution of Hearing and Tumor Size in Natural Course and after Treatment by LINAC Stereotactic Radiosurgery.
Alexandros G. SfakianakisστοHead and NeckΠριν από 2 ώρες
*Vestibular Schwannoma: The Evolution of Hearing and Tumor Size in Natural Course and after Treatment by LINAC Stereotactic Radiosurgery.* Audiol Neurootol. 2015 Nov 17;20(6):406-415 Authors: Ikonomidis C, Pica A, Bloch J, Maire R Abstract OBJECTIVE: To review the natural course of tumor size and hearing during conservative management of 151 patients with unilateral vestibular schwannoma (VS), and to evaluate the same parameters for the part of the group (n = 84) who were treated by LINAC stereotactic radiosurgery (SRS). METHODS: In prospectively collected data, patients underwent... περισσότερα »
Alexandros G. SfakianakisστοHead and NeckΠριν από 2 ώρες
*Vestibular Schwannoma: The Evolution of Hearing and Tumor Size in Natural Course and after Treatment by LINAC Stereotactic Radiosurgery.* Audiol Neurootol. 2015 Nov 17;20(6):406-415 Authors: Ikonomidis C, Pica A, Bloch J, Maire R Abstract OBJECTIVE: To review the natural course of tumor size and hearing during conservative management of 151 patients with unilateral vestibular schwannoma (VS), and to evaluate the same parameters for the part of the group (n = 84) who were treated by LINAC stereotactic radiosurgery (SRS). METHODS: In prospectively collected data, patients underwent... περισσότερα »
Effectiveness and safety of cyclosporine in pediatric plaque psoriasis: a multicentric retrospective analysis.
Alexandros G. SfakianakisστοHead and NeckΠριν από 2 ώρες
*Effectiveness and safety of cyclosporine in pediatric plaque psoriasis: a multicentric retrospective analysis.* J Dermatolog Treat. 2015 Nov 16;:1-15 Authors: Di Lernia V, Stingeni L, Boccaletti V, Calzavara Pinton PG, Guarneri C, Belloni Fortina A, Panzone M, Corazza M, Neri I, Cambiaghi S, Lasagni C, Ficarelli E, Gisondi P Abstract Cyclosporine (CysA) is effective for psoriasis in adult patients but little data exist about its efficacy and safety in childhood and adolescence psoriasis. OBJECTIVES: To assess the effectiveness and safety of CysA for childhood and adolescence ps... περισσότερα »
Alexandros G. SfakianakisστοHead and NeckΠριν από 2 ώρες
*Effectiveness and safety of cyclosporine in pediatric plaque psoriasis: a multicentric retrospective analysis.* J Dermatolog Treat. 2015 Nov 16;:1-15 Authors: Di Lernia V, Stingeni L, Boccaletti V, Calzavara Pinton PG, Guarneri C, Belloni Fortina A, Panzone M, Corazza M, Neri I, Cambiaghi S, Lasagni C, Ficarelli E, Gisondi P Abstract Cyclosporine (CysA) is effective for psoriasis in adult patients but little data exist about its efficacy and safety in childhood and adolescence psoriasis. OBJECTIVES: To assess the effectiveness and safety of CysA for childhood and adolescence ps... περισσότερα »
Tumor Volumes and Prognosis in Laryngeal Cancer.
Alexandros G. SfakianakisστοHead and NeckΠριν από 2 ώρες
*Tumor Volumes and Prognosis in Laryngeal Cancer.* Cancers (Basel). 2015;7(4):2236-2261 Authors: Issa MR, Samuels SE, Bellile E, Shalabi FL, Eisbruch A, Wolf G Abstract Tumor staging systems for laryngeal cancer (LC) have been developed to assist in estimating prognosis after treatment and comparing treatment results across institutions. While the laryngeal TNM system has been shown to have prognostic information, varying cure rates in the literature have suggested concern about the accuracy and effectiveness of the T-classification in particular. To test the hypothesis that tumo...περισσότερα »
Alexandros G. SfakianakisστοHead and NeckΠριν από 2 ώρες
*Tumor Volumes and Prognosis in Laryngeal Cancer.* Cancers (Basel). 2015;7(4):2236-2261 Authors: Issa MR, Samuels SE, Bellile E, Shalabi FL, Eisbruch A, Wolf G Abstract Tumor staging systems for laryngeal cancer (LC) have been developed to assist in estimating prognosis after treatment and comparing treatment results across institutions. While the laryngeal TNM system has been shown to have prognostic information, varying cure rates in the literature have suggested concern about the accuracy and effectiveness of the T-classification in particular. To test the hypothesis that tumo...περισσότερα »
Pneumococcal Mastoiditis in Children Before and After the Introduction of Conjugate Pneumococcal Vaccines.
Alexandros G. SfakianakisστοHead and NeckΠριν από 2 ώρες
*Pneumococcal Mastoiditis in Children Before and After the Introduction of Conjugate Pneumococcal Vaccines.* Pediatr Infect Dis J. 2015 Nov 12; Authors: Koutouzis EI, Michos A, Koutouzi FI, Chatzichristou P, Parpounas K, Georgaki A, Theodoridou M, Tsakris A, Syriopoulou VP Abstract OBJECTIVES: To determine whether serotype distribution and antibiotic resistance of S. pneumoniae acute mastoiditis (AM) in children have changed in the post pneumococcal conjugate vaccines (PCVs) era. METHODS: Medical records of pneumococcal AM cases, in a tertiary Pediatric Hospital were reviewed fro... περισσότερα »
Alexandros G. SfakianakisστοHead and NeckΠριν από 2 ώρες
*Pneumococcal Mastoiditis in Children Before and After the Introduction of Conjugate Pneumococcal Vaccines.* Pediatr Infect Dis J. 2015 Nov 12; Authors: Koutouzis EI, Michos A, Koutouzi FI, Chatzichristou P, Parpounas K, Georgaki A, Theodoridou M, Tsakris A, Syriopoulou VP Abstract OBJECTIVES: To determine whether serotype distribution and antibiotic resistance of S. pneumoniae acute mastoiditis (AM) in children have changed in the post pneumococcal conjugate vaccines (PCVs) era. METHODS: Medical records of pneumococcal AM cases, in a tertiary Pediatric Hospital were reviewed fro... περισσότερα »
Point-of-Care Ultrasound to Diagnose Infantile Parotid Hemangioma.
Alexandros G. SfakianakisστοHead and NeckΠριν από 2 ώρες
*Point-of-Care Ultrasound to Diagnose Infantile Parotid Hemangioma.* Pediatr Emerg Care. 2015 Nov 13; Authors: Crow E, Kang TL Abstract Soft tissue masses are common in the pediatric population and may represent a broad range of conditions. Point-of-care ultrasound can be used for rapid visualization and assessment of soft tissue masses in the emergency setting. We report a case of a pediatric head and neck mass in which point-of-care ultrasound was used to identify an infantile parotid hemangioma. PMID: 26569077 [PubMed - as supplied by publisher] from #PubMed 1 via ola Kala ... περισσότερα »
Alexandros G. SfakianakisστοHead and NeckΠριν από 2 ώρες
*Point-of-Care Ultrasound to Diagnose Infantile Parotid Hemangioma.* Pediatr Emerg Care. 2015 Nov 13; Authors: Crow E, Kang TL Abstract Soft tissue masses are common in the pediatric population and may represent a broad range of conditions. Point-of-care ultrasound can be used for rapid visualization and assessment of soft tissue masses in the emergency setting. We report a case of a pediatric head and neck mass in which point-of-care ultrasound was used to identify an infantile parotid hemangioma. PMID: 26569077 [PubMed - as supplied by publisher] from #PubMed 1 via ola Kala ... περισσότερα »
A Rare Case of Aneurysmal Bone Cyst in the Paranasal Sinus.
Alexandros G. SfakianakisστοHead and NeckΠριν από 2 ώρες
*A Rare Case of Aneurysmal Bone Cyst in the Paranasal Sinus.* Iran J Otorhinolaryngol. 2015 Sep;27(82):395-9 Authors: Hashemi SM, Heidarpour M, Eshaghian A, Ansari P, Hashemi MS, Yaghoobi M, Barati S Abstract INTRODUCTION: Aneurysmal Bone cysts (ABC) are extremely rare in the head and neck region and even rarer in sinuses. ABC is a benign multicystic mass that is locally-destructive and rapidly expandable. Hemorrhagic fluid content (like in this case) and septated appearance are the characteristic feature of ABC. Established treatment options for ABCs include sclerotherapy, embo... περισσότερα »
Alexandros G. SfakianakisστοHead and NeckΠριν από 2 ώρες
*A Rare Case of Aneurysmal Bone Cyst in the Paranasal Sinus.* Iran J Otorhinolaryngol. 2015 Sep;27(82):395-9 Authors: Hashemi SM, Heidarpour M, Eshaghian A, Ansari P, Hashemi MS, Yaghoobi M, Barati S Abstract INTRODUCTION: Aneurysmal Bone cysts (ABC) are extremely rare in the head and neck region and even rarer in sinuses. ABC is a benign multicystic mass that is locally-destructive and rapidly expandable. Hemorrhagic fluid content (like in this case) and septated appearance are the characteristic feature of ABC. Established treatment options for ABCs include sclerotherapy, embo... περισσότερα »
Deep benign fibrous histiocytoma in the oral cavity: a case report.
Alexandros G. SfakianakisστοHead and NeckΠριν από 2 ώρες
*Deep benign fibrous histiocytoma in the oral cavity: a case report.* J Korean Assoc Oral Maxillofac Surg. 2015 Oct;41(5):270-2 Authors: Jo E, Cho ES, Kim HS, Nam W Abstract Benign fibrous histiocytoma (FH) is a benign tumor composed of fibroblasts and histiocytes in varying proportions. This tumor is usually found in adult extremities but rarely occurs in deep soft tissues of the oral cavity. As it is difficult to diagnose with physical and radiologic exams, deep benign FH can only be diagnosed by histopathology. We report a case of a 36-year-old female patient who came to our d...περισσότερα »
Alexandros G. SfakianakisστοHead and NeckΠριν από 2 ώρες
*Deep benign fibrous histiocytoma in the oral cavity: a case report.* J Korean Assoc Oral Maxillofac Surg. 2015 Oct;41(5):270-2 Authors: Jo E, Cho ES, Kim HS, Nam W Abstract Benign fibrous histiocytoma (FH) is a benign tumor composed of fibroblasts and histiocytes in varying proportions. This tumor is usually found in adult extremities but rarely occurs in deep soft tissues of the oral cavity. As it is difficult to diagnose with physical and radiologic exams, deep benign FH can only be diagnosed by histopathology. We report a case of a 36-year-old female patient who came to our d...περισσότερα »
Honey and Radiation-Induced Stomatitis in Patients With Head and Neck Cancer.
Alexandros G. SfakianakisστοHead and NeckΠριν από 2 ώρες
*Honey and Radiation-Induced Stomatitis in Patients With Head and Neck Cancer.* Iran Red Crescent Med J. 2015 Oct;17(10):e19256 Authors: Bahramnezhad F, Dehghan Nayeri N, Bassampour SS, Khajeh M, Asgari P Abstract BACKGROUND: Stomatitis is a common oral complication which affects 100% of patients undergoing head and neck radiotherapy. Acute stomatitis might cause failure and delay radiotherapy. Attention to mouth hygiene, particularly using mouthwash, has a fundamental importance for these patients. OBJECTIVES: The current study came to addresses the effects of pure natural hone... περισσότερα »
Alexandros G. SfakianakisστοHead and NeckΠριν από 2 ώρες
*Honey and Radiation-Induced Stomatitis in Patients With Head and Neck Cancer.* Iran Red Crescent Med J. 2015 Oct;17(10):e19256 Authors: Bahramnezhad F, Dehghan Nayeri N, Bassampour SS, Khajeh M, Asgari P Abstract BACKGROUND: Stomatitis is a common oral complication which affects 100% of patients undergoing head and neck radiotherapy. Acute stomatitis might cause failure and delay radiotherapy. Attention to mouth hygiene, particularly using mouthwash, has a fundamental importance for these patients. OBJECTIVES: The current study came to addresses the effects of pure natural hone... περισσότερα »
Correlation Between Tympanosclerosis and Helicobacter pylori.
Alexandros G. SfakianakisστοHead and NeckΠριν από 2 ώρες
*Correlation Between Tympanosclerosis and Helicobacter pylori.* Jundishapur J Microbiol. 2015 Oct;8(10):e16069 Authors: Saki N, Jahani M, Samarbaf A, Kaydani GA, Nikakhlagh S, Kenani M, Mogehi S Abstract BACKGROUND: Tympanosclerosis is a condition caused by calcification of tissues in the middle ear mucosa that sometimes results hearing loss. Helicobacter pylori is one of the pathological and etiologic factors in the development of tympanosclerosis. OBJECTIVES: The purpose of this study was to show the role of H. pylori in the different aspects of chronic suppurative otitis media... περισσότερα »
Alexandros G. SfakianakisστοHead and NeckΠριν από 2 ώρες
*Correlation Between Tympanosclerosis and Helicobacter pylori.* Jundishapur J Microbiol. 2015 Oct;8(10):e16069 Authors: Saki N, Jahani M, Samarbaf A, Kaydani GA, Nikakhlagh S, Kenani M, Mogehi S Abstract BACKGROUND: Tympanosclerosis is a condition caused by calcification of tissues in the middle ear mucosa that sometimes results hearing loss. Helicobacter pylori is one of the pathological and etiologic factors in the development of tympanosclerosis. OBJECTIVES: The purpose of this study was to show the role of H. pylori in the different aspects of chronic suppurative otitis media... περισσότερα »
Evolving paradigm in treatment of Merkel cell carcinoma of the digit from ray resection to wide local excision and flap coverage.
Alexandros G. SfakianakisστοHead and NeckΠριν από 2 ώρες
*Evolving paradigm in treatment of Merkel cell carcinoma of the digit from ray resection to wide local excision and flap coverage.* Hand (N Y). 2015 Dec;10(4):738-40 Authors: Doermann AJ, G Jakowatz J, F Jones N Abstract BACKGROUND: Merkel cell carcinoma is a rare cutaneous neuroendocrine neoplasm that typically presents on the head and neck. Merkel cell carcinoma (MCC) of the digits is rare, and thus limited treatment options have been presented. METHODS: In contrast to the current treatment recommendation of ray resection of the affected digit, two patients were treated by sent...περισσότερα »
Alexandros G. SfakianakisστοHead and NeckΠριν από 2 ώρες
*Evolving paradigm in treatment of Merkel cell carcinoma of the digit from ray resection to wide local excision and flap coverage.* Hand (N Y). 2015 Dec;10(4):738-40 Authors: Doermann AJ, G Jakowatz J, F Jones N Abstract BACKGROUND: Merkel cell carcinoma is a rare cutaneous neuroendocrine neoplasm that typically presents on the head and neck. Merkel cell carcinoma (MCC) of the digits is rare, and thus limited treatment options have been presented. METHODS: In contrast to the current treatment recommendation of ray resection of the affected digit, two patients were treated by sent...περισσότερα »
New Diseases and New Treatments-Head and Neck Cancer Updates.
Alexandros G. SfakianakisστοHead and NeckΠριν από 2 ώρες
*New Diseases and New Treatments-Head and Neck Cancer Updates.* Hematol Oncol Clin North Am. 2015 Dec;29(6):xiii-xiv Authors: Colevas AD PMID: 26568555 [PubMed - in process] from #PubMed 1 via ola Kala on Inoreader http://ift.tt/1lst9mp via IFTTT
Alexandros G. SfakianakisστοHead and NeckΠριν από 2 ώρες
*New Diseases and New Treatments-Head and Neck Cancer Updates.* Hematol Oncol Clin North Am. 2015 Dec;29(6):xiii-xiv Authors: Colevas AD PMID: 26568555 [PubMed - in process] from #PubMed 1 via ola Kala on Inoreader http://ift.tt/1lst9mp via IFTTT
Supportive Care and Survivorship Strategies in Management of Squamous Cell Carcinoma of the Head and Neck.
Alexandros G. SfakianakisστοHead and NeckΠριν από 2 ώρες
*Supportive Care and Survivorship Strategies in Management of Squamous Cell Carcinoma of the Head and Neck.* Hematol Oncol Clin North Am. 2015 Dec;29(6):1159-68 Authors: Panwar A, Cheung VW, Lydiatt WM Abstract Supportive care and survivorship strategies in the management of head and neck squamous cell carcinoma (HNSCC) revolve around continued collaborative efforts aimed at early identification and intervention for locoregional disease recurrence, second primary malignancy, management of treatment-related side effects, and provision for psychosocial support. Development of evid...περισσότερα »
Alexandros G. SfakianakisστοHead and NeckΠριν από 2 ώρες
*Supportive Care and Survivorship Strategies in Management of Squamous Cell Carcinoma of the Head and Neck.* Hematol Oncol Clin North Am. 2015 Dec;29(6):1159-68 Authors: Panwar A, Cheung VW, Lydiatt WM Abstract Supportive care and survivorship strategies in the management of head and neck squamous cell carcinoma (HNSCC) revolve around continued collaborative efforts aimed at early identification and intervention for locoregional disease recurrence, second primary malignancy, management of treatment-related side effects, and provision for psychosocial support. Development of evid...περισσότερα »
Salivary Gland Malignancies.
Alexandros G. SfakianakisστοHead and NeckΠριν από 2 ώρες
*Salivary Gland Malignancies.* Hematol Oncol Clin North Am. 2015 Dec;29(6):1145-57 Authors: Rodriguez CP, Parvathaneni U, Méndez E, Martins RG Abstract Salivary gland malignant tumors represent a diverse group of neoplasms. Their low incidence makes research studies challenging, with most therapeutic recommendations based on case reviews, single-arm trials, or small randomized trials. The standard of care for localized disease is surgical resection. Radiotherapy is the preferred local therapy when surgery is not possible or if there is significant morbidity. When symptomatic met...περισσότερα »
Alexandros G. SfakianakisστοHead and NeckΠριν από 2 ώρες
*Salivary Gland Malignancies.* Hematol Oncol Clin North Am. 2015 Dec;29(6):1145-57 Authors: Rodriguez CP, Parvathaneni U, Méndez E, Martins RG Abstract Salivary gland malignant tumors represent a diverse group of neoplasms. Their low incidence makes research studies challenging, with most therapeutic recommendations based on case reviews, single-arm trials, or small randomized trials. The standard of care for localized disease is surgical resection. Radiotherapy is the preferred local therapy when surgery is not possible or if there is significant morbidity. When symptomatic met...περισσότερα »
Thyroid Gland Malignancies.
Alexandros G. SfakianakisστοHead and NeckΠριν από 2 ώρες
*Thyroid Gland Malignancies.* Hematol Oncol Clin North Am. 2015 Dec;29(6):1123-43 Authors: Cabanillas ME, Dadu R, Hu MI, Lu C, Gunn GB, Grubbs EG, Lai SY, Williams MD Abstract Surgery remains the most important effective treatment for differentiated (DTC) and medullary thyroid cancer (MTC). Radioactive iodine (RAI) is another important treatment but is reserved only for DTC whose disease captures RAI. Once patients fail primary therapy, observation is often recommended, as most DTC and MTC patients will have indolent disease. However, in a fraction of patients, systemic therapy ...περισσότερα »
Alexandros G. SfakianakisστοHead and NeckΠριν από 2 ώρες
*Thyroid Gland Malignancies.* Hematol Oncol Clin North Am. 2015 Dec;29(6):1123-43 Authors: Cabanillas ME, Dadu R, Hu MI, Lu C, Gunn GB, Grubbs EG, Lai SY, Williams MD Abstract Surgery remains the most important effective treatment for differentiated (DTC) and medullary thyroid cancer (MTC). Radioactive iodine (RAI) is another important treatment but is reserved only for DTC whose disease captures RAI. Once patients fail primary therapy, observation is often recommended, as most DTC and MTC patients will have indolent disease. However, in a fraction of patients, systemic therapy ...περισσότερα »
upper respiratory tract infection; +69 new citations
Alexandros G. SfakianakisστοHead and NeckΠριν από 2 ώρες
69 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: *upper respiratory tract infection* These pubmed results were generated on 2015/11/17 PubMed comprises more than 24 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites. from #PubMed 2 via ola Kala on Inoreader http://ift.tt/QGMHBq(((upper%20respiratory%20tract%20infection)%20AND%20%222015%2F11%2F15%2006.51%22%5B...περισσότερα »
Alexandros G. SfakianakisστοHead and NeckΠριν από 2 ώρες
69 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: *upper respiratory tract infection* These pubmed results were generated on 2015/11/17 PubMed comprises more than 24 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites. from #PubMed 2 via ola Kala on Inoreader http://ift.tt/QGMHBq(((upper%20respiratory%20tract%20infection)%20AND%20%222015%2F11%2F15%2006.51%22%5B...περισσότερα »
SS18-SSX, the Oncogenic Fusion Protein in Synovial Sarcoma, Is a Cellular Context-Dependent Epigenetic Modifier.
Alexandros G. SfakianakisστοHead and NeckΠριν από 2 ώρες
*SS18-SSX, the Oncogenic Fusion Protein in Synovial Sarcoma, Is a Cellular Context-Dependent Epigenetic Modifier.* PLoS One. 2015;10(11):e0142991 Authors: Tamaki S, Fukuta M, Sekiguchi K, Jin Y, Nagata S, Hayakawa K, Hineno S, Okamoto T, Watanabe M, Woltjen K, Ikeya M, Kato T, Toguchida J Abstract The prevalence and specificity of unique fusion oncogenes are high in a number of soft tissue sarcomas (STSs). The close relationship between fusion genes and clinicopathological features suggests that a correlation may exist between the function of fusion proteins and cellular context ... περισσότερα »
Alexandros G. SfakianakisστοHead and NeckΠριν από 2 ώρες
*SS18-SSX, the Oncogenic Fusion Protein in Synovial Sarcoma, Is a Cellular Context-Dependent Epigenetic Modifier.* PLoS One. 2015;10(11):e0142991 Authors: Tamaki S, Fukuta M, Sekiguchi K, Jin Y, Nagata S, Hayakawa K, Hineno S, Okamoto T, Watanabe M, Woltjen K, Ikeya M, Kato T, Toguchida J Abstract The prevalence and specificity of unique fusion oncogenes are high in a number of soft tissue sarcomas (STSs). The close relationship between fusion genes and clinicopathological features suggests that a correlation may exist between the function of fusion proteins and cellular context ... περισσότερα »
Frontiers for the early diagnosis of AD by means of MRI brain imaging and Support Vector Machines.
Alexandros G. SfakianakisστοHead and NeckΠριν από 2 ώρες
*Frontiers for the early diagnosis of AD by means of MRI brain imaging and Support Vector Machines.* Curr Alzheimer Res. 2015 Nov 16; Authors: Salvatorea C, Battistaa P, Castiglionia I Abstract The emergence of Alzheimer's Disease (AD) as a consequence of increasing aging population make urgent the availability of methods for the early and accurate diagnosis. Magnetic Resonance Imaging (MRI) could be used as in vivo, non invasive tool to identify sensitive and specific markers of very early AD progression. In recent years, multivariate pattern analysis (MVPA) and machine-learnin... περισσότερα »
Alexandros G. SfakianakisστοHead and NeckΠριν από 2 ώρες
*Frontiers for the early diagnosis of AD by means of MRI brain imaging and Support Vector Machines.* Curr Alzheimer Res. 2015 Nov 16; Authors: Salvatorea C, Battistaa P, Castiglionia I Abstract The emergence of Alzheimer's Disease (AD) as a consequence of increasing aging population make urgent the availability of methods for the early and accurate diagnosis. Magnetic Resonance Imaging (MRI) could be used as in vivo, non invasive tool to identify sensitive and specific markers of very early AD progression. In recent years, multivariate pattern analysis (MVPA) and machine-learnin... περισσότερα »
Future Oncology; +23 new citations
Alexandros G. SfakianakisστοHead and NeckΠριν από 2 ώρες
23 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: *Future Oncology* These pubmed results were generated on 2015/11/17 PubMed comprises more than 24 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites. from #PubMed 3 via ola Kala on Inoreader http://ift.tt/QGMHBq(((Future%20Oncology)%20AND%20%222015%2F11%2F15%2006.15%22%5BMHDA%5D%3A%222015%2F11%2F17%2006.46%22%5... περισσότερα »
Alexandros G. SfakianakisστοHead and NeckΠριν από 2 ώρες
23 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: *Future Oncology* These pubmed results were generated on 2015/11/17 PubMed comprises more than 24 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites. from #PubMed 3 via ola Kala on Inoreader http://ift.tt/QGMHBq(((Future%20Oncology)%20AND%20%222015%2F11%2F15%2006.15%22%5BMHDA%5D%3A%222015%2F11%2F17%2006.46%22%5... περισσότερα »
Evaluation of wideband frequency responses and non-linear frequency compression for children with mild to moderate high-frequency hearing loss.
Alexandros G. SfakianakisστοHead and NeckΠριν από 2 ώρες
[image: http:--http://ift.tt/1XLQsFQ] Related Articles *Evaluation of wideband frequency responses and non-linear frequency compression for children with mild to moderate high-frequency hearing loss.* Int J Audiol. 2015 Mar;54(3):170-81 Authors: Wolfe J, John A, Schafer E, Hudson M, Boretzki M, Scollie S, Woods W, Wheeler J, Hudgens K, Neumann S Abstract OBJECTIVE: To evaluate wideband amplification and non-linear frequency compression (NLFC) as a means to improve speech recognition for children with mild/moderate hearing loss. DESIGN: Randomized within-subject design with repeate...περισσότερα »
Alexandros G. SfakianakisστοHead and NeckΠριν από 2 ώρες
[image: http:--http://ift.tt/1XLQsFQ] Related Articles *Evaluation of wideband frequency responses and non-linear frequency compression for children with mild to moderate high-frequency hearing loss.* Int J Audiol. 2015 Mar;54(3):170-81 Authors: Wolfe J, John A, Schafer E, Hudson M, Boretzki M, Scollie S, Woods W, Wheeler J, Hudgens K, Neumann S Abstract OBJECTIVE: To evaluate wideband amplification and non-linear frequency compression (NLFC) as a means to improve speech recognition for children with mild/moderate hearing loss. DESIGN: Randomized within-subject design with repeate...περισσότερα »
Acute heart failure in the emergency department: a follow-up study
Alexandros G. SfakianakisστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 2 ώρες
Internal and Emergency Medicine from Emergency Medicine via ola Kala on Inoreader http://ift.tt/20YQWuK via IFTTT
Alexandros G. SfakianakisστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 2 ώρες
Internal and Emergency Medicine from Emergency Medicine via ola Kala on Inoreader http://ift.tt/20YQWuK via IFTTT
Development of a consensus statement for the definition, diagnosis, and treatment of acute exacerbations of idiopathic pulmonary fibrosis using the Delphi technique
Alexandros G. SfakianakisστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 2 ώρες
Advances in Therapy from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1S0Pj9Q via IFTTT
Alexandros G. SfakianakisστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 2 ώρες
Advances in Therapy from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1S0Pj9Q via IFTTT
Minimally-invasive plate osteosynthesis in distal tibial fractures: Results and complications
Alexandros G. SfakianakisστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 2 ώρες
Injury from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1S0Pj9M via IFTTT
Alexandros G. SfakianakisστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 2 ώρες
Injury from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1S0Pj9M via IFTTT
Association of bystander and first-responder intervention with survival after out-of-hospital cardiac arrest in North Carolina, 2010-2013
Alexandros G. SfakianakisστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 2 ώρες
The Journal of Emergency Medicine from Emergency Medicine via ola Kala on Inoreader http://ift.tt/20YQVa5 via IFTTT
Alexandros G. SfakianakisστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 2 ώρες
The Journal of Emergency Medicine from Emergency Medicine via ola Kala on Inoreader http://ift.tt/20YQVa5 via IFTTT
Does MIPO of fractures of the distal femur result in more rotational malalignment than ORIF? A retrospective study
Alexandros G. SfakianakisστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 2 ώρες
European Journal of Trauma and Emergency Surgery from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1S0PiTs via IFTTT
Alexandros G. SfakianakisστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 2 ώρες
European Journal of Trauma and Emergency Surgery from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1S0PiTs via IFTTT
Can C-reactive protein and white blood cell count alone rule out an urgent condition in acute abdominal pain?
Alexandros G. SfakianakisστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 2 ώρες
Internal and Emergency Medicine from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1S0PiTm via IFTTT
Alexandros G. SfakianakisστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 2 ώρες
Internal and Emergency Medicine from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1S0PiTm via IFTTT
Diagnosis of occult radial head and neck fracture in adults
Alexandros G. SfakianakisστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 2 ώρες
Injury from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1S0Pimc via IFTTT
Alexandros G. SfakianakisστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 2 ώρες
Injury from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1S0Pimc via IFTTT
A novel tool for continuous fracture aftercare–Clinical feasibility and first results of a new telemetric gait analysis insole
Alexandros G. SfakianakisστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 2 ώρες
Injury from Emergency Medicine via ola Kala on Inoreader http://ift.tt/20YQTiu via IFTTT
Alexandros G. SfakianakisστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 2 ώρες
Injury from Emergency Medicine via ola Kala on Inoreader http://ift.tt/20YQTiu via IFTTT
Air versus oxygen in ST-segment-elevation myocardial infarction
Alexandros G. SfakianakisστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 2 ώρες
The Journal of Emergency Medicine from Emergency Medicine via ola Kala on Inoreader http://ift.tt/20YQUmI via IFTTT
Alexandros G. SfakianakisστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 2 ώρες
The Journal of Emergency Medicine from Emergency Medicine via ola Kala on Inoreader http://ift.tt/20YQUmI via IFTTT
Risk and mortality of gastrointestinal hemorrhage in patients with thrombocytopenia: Two nationwide retrospective cohort studies
Alexandros G. SfakianakisστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 2 ώρες
European Journal of Internal Medicine from Emergency Medicine via ola Kala on Inoreader http://ift.tt/20YQUmB via IFTTT
Alexandros G. SfakianakisστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 2 ώρες
European Journal of Internal Medicine from Emergency Medicine via ola Kala on Inoreader http://ift.tt/20YQUmB via IFTTT
Emergency department quality and safety indicators in resource-limited settings: an environmental survey
Alexandros G. SfakianakisστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 2 ώρες
International Journal of Emergency Medicine from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1S0PfXz via IFTTT
Alexandros G. SfakianakisστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 2 ώρες
International Journal of Emergency Medicine from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1S0PfXz via IFTTT
Emergency laparoscopic sigmoidectomy for perforated diverticulitis with generalised peritonitis: a systematic review
Alexandros G. SfakianakisστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 2 ώρες
Digestive Surgery from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1S0PfXx via IFTTT
Alexandros G. SfakianakisστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 2 ώρες
Digestive Surgery from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1S0PfXx via IFTTT
Effects of protein-rich nutritional supplementation and bisphosphonates on body composition, handgrip strength and health-related quality of life after hip fracture: a 12-month randomized controlled study
Alexandros G. SfakianakisστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 2 ώρες
BMC Geriatrics from Emergency Medicine via ola Kala on Inoreader http://ift.tt/20YQTPH via IFTTT
Alexandros G. SfakianakisστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 2 ώρες
BMC Geriatrics from Emergency Medicine via ola Kala on Inoreader http://ift.tt/20YQTPH via IFTTT
Acute Concussion Management with Remove-Reduce/Educate/Adjust-Accommodate/Pace (REAP)
Alexandros G. SfakianakisστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 2 ώρες
The Journal of Emergency Medicine from Emergency Medicine via ola Kala on Inoreader http://ift.tt/20YQRXX via IFTTT
Alexandros G. SfakianakisστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 2 ώρες
The Journal of Emergency Medicine from Emergency Medicine via ola Kala on Inoreader http://ift.tt/20YQRXX via IFTTT
Ventilation monitoring for severe pediatric traumatic brain injury during interfacility transport
Alexandros G. SfakianakisστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 2 ώρες
International Journal of Emergency Medicine from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1S0PhPn via IFTTT
Alexandros G. SfakianakisστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 2 ώρες
International Journal of Emergency Medicine from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1S0PhPn via IFTTT
Survival rates in trauma patients following health care reform in Massachusetts
Alexandros G. SfakianakisστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 2 ώρες
The Journal of Emergency Medicine from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1S0PhPl via IFTTT
Alexandros G. SfakianakisστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 2 ώρες
The Journal of Emergency Medicine from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1S0PhPl via IFTTT
Evaluation of the effects of nonlinear frequency compression on speech recognition and sound quality for adults with mild to moderate hearing loss.
Alexandros G. SfakianakisστοHead and NeckΠριν από 3 ώρες
[image: http:--http://ift.tt/1XLQsFQ] Related Articles *Evaluation of the effects of nonlinear frequency compression on speech recognition and sound quality for adults with mild to moderate hearing loss.* Int J Audiol. 2015 Mar;54(3):162-9 Authors: Picou EM, Marcrum SC, Ricketts TA Abstract OBJECTIVE: While potentially improving audibility for listeners with considerable high frequency hearing loss, the effects of implementing nonlinear frequency compression (NFC) for listeners with moderate high frequency hearing loss are unclear. The purpose of this study was to investigate th... περισσότερα »
Alexandros G. SfakianakisστοHead and NeckΠριν από 3 ώρες
[image: http:--http://ift.tt/1XLQsFQ] Related Articles *Evaluation of the effects of nonlinear frequency compression on speech recognition and sound quality for adults with mild to moderate hearing loss.* Int J Audiol. 2015 Mar;54(3):162-9 Authors: Picou EM, Marcrum SC, Ricketts TA Abstract OBJECTIVE: While potentially improving audibility for listeners with considerable high frequency hearing loss, the effects of implementing nonlinear frequency compression (NFC) for listeners with moderate high frequency hearing loss are unclear. The purpose of this study was to investigate th... περισσότερα »
Computer-based auditory phoneme discrimination training improves speech recognition in noise in experienced adult cochlear implant listeners.
Alexandros G. SfakianakisστοHead and NeckΠριν από 3 ώρες
[image: http:--http://ift.tt/1XLQsFQ] Related Articles *Computer-based auditory phoneme discrimination training improves speech recognition in noise in experienced adult cochlear implant listeners.* Int J Audiol. 2015 Mar;54(3):190-8 Authors: Schumann A, Serman M, Gefeller O, Hoppe U Abstract OBJECTIVE: Specific computer-based auditory training may be a useful completion in the rehabilitation process for cochlear implant (CI) listeners to achieve sufficient speech intelligibility. This study evaluated the effectiveness of a computerized, phoneme-discrimination training programme.... περισσότερα »
Alexandros G. SfakianakisστοHead and NeckΠριν από 3 ώρες
[image: http:--http://ift.tt/1XLQsFQ] Related Articles *Computer-based auditory phoneme discrimination training improves speech recognition in noise in experienced adult cochlear implant listeners.* Int J Audiol. 2015 Mar;54(3):190-8 Authors: Schumann A, Serman M, Gefeller O, Hoppe U Abstract OBJECTIVE: Specific computer-based auditory training may be a useful completion in the rehabilitation process for cochlear implant (CI) listeners to achieve sufficient speech intelligibility. This study evaluated the effectiveness of a computerized, phoneme-discrimination training programme.... περισσότερα »
Susceptibility of linear and nonlinear otoacoustic emission components to low-dose styrene exposure.
Alexandros G. SfakianakisστοHead and NeckΠριν από 3 ώρες
[image: http:--http://ift.tt/1XLQsFQ] Related Articles *Susceptibility of linear and nonlinear otoacoustic emission components to low-dose styrene exposure.* Int J Audiol. 2015 Mar;54(3):199-209 Authors: Tognola G, Chiaramello E, Sisto R, Moleti A Abstract OBJECTIVE: To investigate potential susceptibility of active cochlear mechanisms to low-level styrene exposure by comparing TEOAEs in workers and controls. DESIGN: Two advanced analysis techniques were applied to detect sub-clinical changes in linear and nonlinear cochlear mechanisms of OAE generation: the wavelet transform to ... περισσότερα »
Alexandros G. SfakianakisστοHead and NeckΠριν από 3 ώρες
[image: http:--http://ift.tt/1XLQsFQ] Related Articles *Susceptibility of linear and nonlinear otoacoustic emission components to low-dose styrene exposure.* Int J Audiol. 2015 Mar;54(3):199-209 Authors: Tognola G, Chiaramello E, Sisto R, Moleti A Abstract OBJECTIVE: To investigate potential susceptibility of active cochlear mechanisms to low-level styrene exposure by comparing TEOAEs in workers and controls. DESIGN: Two advanced analysis techniques were applied to detect sub-clinical changes in linear and nonlinear cochlear mechanisms of OAE generation: the wavelet transform to ... περισσότερα »
Relations between psychophysical measures of spatial hearing and self-reported spatial-hearing abilities.
Alexandros G. SfakianakisστοHead and NeckΠριν από 3 ώρες
[image: http:--http://ift.tt/1XLQsFQ] Related Articles *Relations between psychophysical measures of spatial hearing and self-reported spatial-hearing abilities.* Int J Audiol. 2015 Mar;54(3):182-9 Authors: Van Esch TE, Lutman ME, Vormann M, Lyzenga J, Hällgren M, Larsby B, Athalye SP, Houtgast T, Kollmeier B, Dreschler WA Abstract OBJECTIVE: The aim of the present study was to investigate how well the virtual psychophysical measures of spatial hearing from the preliminary auditory profile predict self-reported spatial-hearing abilities. DESIGN: Virtual spatial-hearings tests (con... περισσότερα »
Alexandros G. SfakianakisστοHead and NeckΠριν από 3 ώρες
[image: http:--http://ift.tt/1XLQsFQ] Related Articles *Relations between psychophysical measures of spatial hearing and self-reported spatial-hearing abilities.* Int J Audiol. 2015 Mar;54(3):182-9 Authors: Van Esch TE, Lutman ME, Vormann M, Lyzenga J, Hällgren M, Larsby B, Athalye SP, Houtgast T, Kollmeier B, Dreschler WA Abstract OBJECTIVE: The aim of the present study was to investigate how well the virtual psychophysical measures of spatial hearing from the preliminary auditory profile predict self-reported spatial-hearing abilities. DESIGN: Virtual spatial-hearings tests (con... περισσότερα »
cVEMPs: a systematic review and meta-analysis.
Alexandros G. SfakianakisστοHead and NeckΠριν από 3 ώρες
[image: http:--http://ift.tt/1XLQsFQ] Related Articles *cVEMPs: a systematic review and meta-analysis.* Int J Audiol. 2015 Mar;54(3):143-51 Authors: Meyer N, Vinck B, Heinze B Abstract OBJECTIVE: A systematic literature review and meta-analysis was performed to determine the effect of stimulus type, SCM muscle activation method, transducer type, and method to control SCM muscle EMG level on response parameter values for 0.1-ms click-evoked and 500-Hz tone burst cVEMPs. A description of normative response values was attempted. DESIGN: An electronic systematic literature review was ... περισσότερα »
Alexandros G. SfakianakisστοHead and NeckΠριν από 3 ώρες
[image: http:--http://ift.tt/1XLQsFQ] Related Articles *cVEMPs: a systematic review and meta-analysis.* Int J Audiol. 2015 Mar;54(3):143-51 Authors: Meyer N, Vinck B, Heinze B Abstract OBJECTIVE: A systematic literature review and meta-analysis was performed to determine the effect of stimulus type, SCM muscle activation method, transducer type, and method to control SCM muscle EMG level on response parameter values for 0.1-ms click-evoked and 500-Hz tone burst cVEMPs. A description of normative response values was attempted. DESIGN: An electronic systematic literature review was ... περισσότερα »
Hearing-aid use and its determinants in the UK National Health Service: a cross-sectional study at the Royal Surrey County Hospital.
Alexandros G. SfakianakisστοHead and NeckΠριν από 3 ώρες
[image: http:--http://ift.tt/1XLQsFQ] Related Articles *Hearing-aid use and its determinants in the UK National Health Service: a cross-sectional study at the Royal Surrey County Hospital.* Int J Audiol. 2015 Mar;54(3):152-61 Authors: Aazh H, Prasher D, Nanchahal K, Moore BC Abstract OBJECTIVES: The aim of this study was to investigate the rate of and factors contributing to non-adherence to hearing-aid use in the UK National Health Service. DESIGN: A cross-sectional postal questionnaire survey. STUDY SAMPLE: A questionnaire, including the International Outcome Inventory for Heari...περισσότερα »
Alexandros G. SfakianakisστοHead and NeckΠριν από 3 ώρες
[image: http:--http://ift.tt/1XLQsFQ] Related Articles *Hearing-aid use and its determinants in the UK National Health Service: a cross-sectional study at the Royal Surrey County Hospital.* Int J Audiol. 2015 Mar;54(3):152-61 Authors: Aazh H, Prasher D, Nanchahal K, Moore BC Abstract OBJECTIVES: The aim of this study was to investigate the rate of and factors contributing to non-adherence to hearing-aid use in the UK National Health Service. DESIGN: A cross-sectional postal questionnaire survey. STUDY SAMPLE: A questionnaire, including the International Outcome Inventory for Heari...περισσότερα »
Precision medicine ethics: selected issues and developments in next-generation sequencing, clinical oncology, and ethics.
Alexandros G. SfakianakisστοHead and NeckΠριν από 3 ώρες
*Precision medicine ethics: selected issues and developments in next-generation sequencing, clinical oncology, and ethics.* Curr Opin Oncol. 2015 Nov 13; Authors: Fiore RN, Goodman KW Abstract PURPOSE OF REVIEW: In early 2015 the National Institutes of Health launched a new, national Precision Medicine Initiative with the primary goal of rapidly improving the prevention, diagnosis, and treatment of cancers. The first-stage emphasis on oncology presents unique opportunities for clinical oncology to influence how the ethical challenges of precision medicine are to be articulated a...περισσότερα »
Alexandros G. SfakianakisστοHead and NeckΠριν από 3 ώρες
*Precision medicine ethics: selected issues and developments in next-generation sequencing, clinical oncology, and ethics.* Curr Opin Oncol. 2015 Nov 13; Authors: Fiore RN, Goodman KW Abstract PURPOSE OF REVIEW: In early 2015 the National Institutes of Health launched a new, national Precision Medicine Initiative with the primary goal of rapidly improving the prevention, diagnosis, and treatment of cancers. The first-stage emphasis on oncology presents unique opportunities for clinical oncology to influence how the ethical challenges of precision medicine are to be articulated a...περισσότερα »
MicroRNA networks in pulmonary arterial hypertension: share mechanisms with cancer?
Alexandros G. SfakianakisστοHead and NeckΠριν από 3 ώρες
*MicroRNA networks in pulmonary arterial hypertension: share mechanisms with cancer?* Curr Opin Oncol. 2015 Nov 13; Authors: Courboulin A, Ranchoux B, Cohen-Kaminsky S, Perros F, Bonnet S Abstract PURPOSE OF REVIEW: Pulmonary arterial hypertension (PAH) is a rare disease with poor prognosis and no therapeutics. PAH is characterized by severe remodeling of precapillary pulmonary arteries, leading to increased vascular resistance, pulmonary hypertension compensatory right ventricular hypertrophy, then heart failure and death. PAH pathogenesis shares similarities with carcinogenesi... περισσότερα »
Alexandros G. SfakianakisστοHead and NeckΠριν από 3 ώρες
*MicroRNA networks in pulmonary arterial hypertension: share mechanisms with cancer?* Curr Opin Oncol. 2015 Nov 13; Authors: Courboulin A, Ranchoux B, Cohen-Kaminsky S, Perros F, Bonnet S Abstract PURPOSE OF REVIEW: Pulmonary arterial hypertension (PAH) is a rare disease with poor prognosis and no therapeutics. PAH is characterized by severe remodeling of precapillary pulmonary arteries, leading to increased vascular resistance, pulmonary hypertension compensatory right ventricular hypertrophy, then heart failure and death. PAH pathogenesis shares similarities with carcinogenesi... περισσότερα »
Inflammatory Myofibroblastic Tumor of the Lung: Unusual Imaging Findings of Three Cases.
Alexandros G. SfakianakisστοHead and NeckΠριν από 3 ώρες
*Inflammatory Myofibroblastic Tumor of the Lung: Unusual Imaging Findings of Three Cases.* Pol J Radiol. 2015;80:479-82 Authors: Ufuk F, Herek D, Karabulut N Abstract BACKGROUND: Inflammatory myofibroblastic tumor (IMT), also known as inflammatory pseudotumor, is a benign disorder composed of fibrous tissues, myofibroblasts and inflammatory cell proliferation with obscure etiology. Although it is the most common lung tumor in children, it is seen rarely in adults constituting less than 1% of adult lung tumors. CASE REPORTS: In this report, we present different and rare CT manife...περισσότερα »
Alexandros G. SfakianakisστοHead and NeckΠριν από 3 ώρες
*Inflammatory Myofibroblastic Tumor of the Lung: Unusual Imaging Findings of Three Cases.* Pol J Radiol. 2015;80:479-82 Authors: Ufuk F, Herek D, Karabulut N Abstract BACKGROUND: Inflammatory myofibroblastic tumor (IMT), also known as inflammatory pseudotumor, is a benign disorder composed of fibrous tissues, myofibroblasts and inflammatory cell proliferation with obscure etiology. Although it is the most common lung tumor in children, it is seen rarely in adults constituting less than 1% of adult lung tumors. CASE REPORTS: In this report, we present different and rare CT manife...περισσότερα »
Metastatic cardiac tumor from urothelial carcinoma detected by transthoracic echocardiography: a case report.
Alexandros G. SfakianakisστοHead and NeckΠριν από 3 ώρες
*Metastatic cardiac tumor from urothelial carcinoma detected by transthoracic echocardiography: a case report.* J Med Case Rep. 2015;9(1):257 Authors: Nakashima Y, Tanioka K, Kubo T, Yamasaki N, Yamasaki I, Syuin T, Kitaoka H Abstract INTRODUCTION: Cardiac metastasis of urothelial carcinoma is a very rare but clinically important complication. Most cardiac metastases are asymptomatic; symptoms from cardiac metastasis were seen in advanced stage and many of these cases were reported to have a poor prognosis. So it is important to find asymptomatic cardiac metastasis and to start ...περισσότερα »
Alexandros G. SfakianakisστοHead and NeckΠριν από 3 ώρες
*Metastatic cardiac tumor from urothelial carcinoma detected by transthoracic echocardiography: a case report.* J Med Case Rep. 2015;9(1):257 Authors: Nakashima Y, Tanioka K, Kubo T, Yamasaki N, Yamasaki I, Syuin T, Kitaoka H Abstract INTRODUCTION: Cardiac metastasis of urothelial carcinoma is a very rare but clinically important complication. Most cardiac metastases are asymptomatic; symptoms from cardiac metastasis were seen in advanced stage and many of these cases were reported to have a poor prognosis. So it is important to find asymptomatic cardiac metastasis and to start ...περισσότερα »
Gastric leiomyoma in a child with Gorlin-Goltz syndrome: First pediatric case.
Alexandros G. SfakianakisστοHead and NeckΠριν από 3 ώρες
*Gastric leiomyoma in a child with Gorlin-Goltz syndrome: First pediatric case.* Pediatr Int. 2015 Nov 16; Authors: Virgone C, Decker E, Mitton SG, Mansour S, Giuliani S Abstract Gorlin-Goltz syndrome (GGS), also known as nevoid basal cell carcinoma syndrome (MIM 109 400), is a rare genetic condition with a prevalence between 1/56 000 and 1/256 000. Clinical presentation is usually characterized by multiple basal cell carcinomas, odontogenic jaw keratocysts, palmar or plantar pitting and skeletal anomalies. It is furthermore associated with the development of various tumors besi... περισσότερα »
Alexandros G. SfakianakisστοHead and NeckΠριν από 3 ώρες
*Gastric leiomyoma in a child with Gorlin-Goltz syndrome: First pediatric case.* Pediatr Int. 2015 Nov 16; Authors: Virgone C, Decker E, Mitton SG, Mansour S, Giuliani S Abstract Gorlin-Goltz syndrome (GGS), also known as nevoid basal cell carcinoma syndrome (MIM 109 400), is a rare genetic condition with a prevalence between 1/56 000 and 1/256 000. Clinical presentation is usually characterized by multiple basal cell carcinomas, odontogenic jaw keratocysts, palmar or plantar pitting and skeletal anomalies. It is furthermore associated with the development of various tumors besi... περισσότερα »
Hyperreactio Luteinalis: Maternal and Fetal Effects.
Alexandros G. SfakianakisστοHead and NeckΠριν από 3 ώρες
Related Articles *Hyperreactio Luteinalis: Maternal and Fetal Effects.* J Obstet Gynaecol Can. 2015 Aug;37(8):715-23 Authors: Malinowski AK, Sen J, Sermer M Abstract Hyperreactio luteinalis is a rare condition in which there is massive cystic enlargement of the ovaries, mimicking malignancy, during pregnancy. When confronted with this condition, the fear of missing a cancer diagnosis often leads the physician to react with unnecessary surgical intervention, potentially resulting in impaired future fertility. The literature on the subject contains mainly case reports and one small... περισσότερα »
Alexandros G. SfakianakisστοHead and NeckΠριν από 3 ώρες
Related Articles *Hyperreactio Luteinalis: Maternal and Fetal Effects.* J Obstet Gynaecol Can. 2015 Aug;37(8):715-23 Authors: Malinowski AK, Sen J, Sermer M Abstract Hyperreactio luteinalis is a rare condition in which there is massive cystic enlargement of the ovaries, mimicking malignancy, during pregnancy. When confronted with this condition, the fear of missing a cancer diagnosis often leads the physician to react with unnecessary surgical intervention, potentially resulting in impaired future fertility. The literature on the subject contains mainly case reports and one small... περισσότερα »
[A Case of Intravascular Lymphoma Mimicking Acute Sinusitis in Which the Outcome was Unfortunate].
Alexandros G. SfakianakisστοHead and NeckΠριν από 3 ώρες
Related Articles *[A Case of Intravascular Lymphoma Mimicking Acute Sinusitis in Which the Outcome was Unfortunate].* Nihon Jibiinkoka Gakkai Kaiho. 2015 Jun;118(6):770-5 Authors: Kambara R, Horii A, Osak Y, Inohara H Abstract Intravascular large B-cell lymphomas (IVLBCL) are a rare and aggressive non-Hodgkin Lymphoma characterized by proliferation of malignant lymphoid cells into the small blood vessels of the whole body. Making a diagnosis is very difficult due to the lack of mass formation and lymph node enlargement, resulting in a poor prognosis. We report herein on a case of... περισσότερα »
Alexandros G. SfakianakisστοHead and NeckΠριν από 3 ώρες
Related Articles *[A Case of Intravascular Lymphoma Mimicking Acute Sinusitis in Which the Outcome was Unfortunate].* Nihon Jibiinkoka Gakkai Kaiho. 2015 Jun;118(6):770-5 Authors: Kambara R, Horii A, Osak Y, Inohara H Abstract Intravascular large B-cell lymphomas (IVLBCL) are a rare and aggressive non-Hodgkin Lymphoma characterized by proliferation of malignant lymphoid cells into the small blood vessels of the whole body. Making a diagnosis is very difficult due to the lack of mass formation and lymph node enlargement, resulting in a poor prognosis. We report herein on a case of... περισσότερα »
Primary Pulmonary Synovial Sarcoma in a Tertiary Referral Center: Clinical Characteristics, CT, and 18F-FDG PET Findings, With Pathologic Correlations.
Alexandros G. SfakianakisστοHead and NeckΠριν από 3 ώρες
[image: http:--pt.wkhealth.com-pt-pt-core-templa] [image: http:--http://ift.tt/1Fkw4zC] Related Articles *Primary Pulmonary Synovial Sarcoma in a Tertiary Referral Center: Clinical Characteristics, CT, and 18F-FDG PET Findings, With Pathologic Correlations.* Medicine (Baltimore). 2015 Aug;94(34):e1392 Authors: Kim GH, Kim MY, Koo HJ, Song JS, Choi CM Abstract The purpose of this study was to describe the patient characteristics, computed tomography (CT) and F-fluorodeoxyglucose positron emission tomography (FDG PET) findings, and clinical outcomes of primary pulmonary synovial s... περισσότερα »
Alexandros G. SfakianakisστοHead and NeckΠριν από 3 ώρες
[image: http:--pt.wkhealth.com-pt-pt-core-templa] [image: http:--http://ift.tt/1Fkw4zC] Related Articles *Primary Pulmonary Synovial Sarcoma in a Tertiary Referral Center: Clinical Characteristics, CT, and 18F-FDG PET Findings, With Pathologic Correlations.* Medicine (Baltimore). 2015 Aug;94(34):e1392 Authors: Kim GH, Kim MY, Koo HJ, Song JS, Choi CM Abstract The purpose of this study was to describe the patient characteristics, computed tomography (CT) and F-fluorodeoxyglucose positron emission tomography (FDG PET) findings, and clinical outcomes of primary pulmonary synovial s... περισσότερα »
Synchronous Hepatic Epithelioid Hemangioendothelioma and Hepatocellular Carcinoma: First Case Report in the Literature and Challenges.
Alexandros G. SfakianakisστοHead and NeckΠριν από 3 ώρες
[image: http:--pt.wkhealth.com-pt-pt-core-templa] [image: http:--http://ift.tt/1Fkw4zC] Related Articles *Synchronous Hepatic Epithelioid Hemangioendothelioma and Hepatocellular Carcinoma: First Case Report in the Literature and Challenges.* Medicine (Baltimore). 2015 Aug;94(34):e1377 Authors: Athanasopoulos PG, Hadjittofi C, Luong TV, O'Beirne J, Sharma D Abstract We would like to report the first case in English literature, to the best of our knowledge, of a synchronous hepatic epithelioid hemangioendothelioma (HEHE) and hepatocellular carcinoma (HCC), as well as to address the ... περισσότερα »
Alexandros G. SfakianakisστοHead and NeckΠριν από 3 ώρες
[image: http:--pt.wkhealth.com-pt-pt-core-templa] [image: http:--http://ift.tt/1Fkw4zC] Related Articles *Synchronous Hepatic Epithelioid Hemangioendothelioma and Hepatocellular Carcinoma: First Case Report in the Literature and Challenges.* Medicine (Baltimore). 2015 Aug;94(34):e1377 Authors: Athanasopoulos PG, Hadjittofi C, Luong TV, O'Beirne J, Sharma D Abstract We would like to report the first case in English literature, to the best of our knowledge, of a synchronous hepatic epithelioid hemangioendothelioma (HEHE) and hepatocellular carcinoma (HCC), as well as to address the ... περισσότερα »
Complete Intestinal Obstruction and Necrosis as a Complication of a Ventriculoperitoneal Shunt in Children: A Report of 2 Cases and Systematic Literature Review.
Alexandros G. SfakianakisστοHead and NeckΠριν από 3 ώρες
[image: http:--pt.wkhealth.com-pt-pt-core-templa] [image: http:--http://ift.tt/1Fkw4zC] Related Articles *Complete Intestinal Obstruction and Necrosis as a Complication of a Ventriculoperitoneal Shunt in Children: A Report of 2 Cases and Systematic Literature Review.* Medicine (Baltimore). 2015 Aug;94(34):e1375 Authors: Zhao R, Shi W, Yu J, Gao X, Li H Abstract Ventriculoperitoneal (VP) shunt complications are common, but abdominal complications are rare. The objective of this report is to present 2 cases of intestinal obstruction due to a VP shunt and review the literature for ... περισσότερα »
Alexandros G. SfakianakisστοHead and NeckΠριν από 3 ώρες
[image: http:--pt.wkhealth.com-pt-pt-core-templa] [image: http:--http://ift.tt/1Fkw4zC] Related Articles *Complete Intestinal Obstruction and Necrosis as a Complication of a Ventriculoperitoneal Shunt in Children: A Report of 2 Cases and Systematic Literature Review.* Medicine (Baltimore). 2015 Aug;94(34):e1375 Authors: Zhao R, Shi W, Yu J, Gao X, Li H Abstract Ventriculoperitoneal (VP) shunt complications are common, but abdominal complications are rare. The objective of this report is to present 2 cases of intestinal obstruction due to a VP shunt and review the literature for ... περισσότερα »
Hepatocellular Carcinoma With Tumor Thrombus Occupying the Right Atrium and Portal Vein: A Case Report and Literature Review.
Alexandros G. SfakianakisστοHead and NeckΠριν από 3 ώρες
[image: http:--pt.wkhealth.com-pt-pt-core-templa] [image: http:--http://ift.tt/1Fkw4zC] Related Articles *Hepatocellular Carcinoma With Tumor Thrombus Occupying the Right Atrium and Portal Vein: A Case Report and Literature Review.* Medicine (Baltimore). 2015 Aug;94(34):e1049 Authors: Luo X, Zhang B, Dong S, Zhang B, Chen X Abstract Hepatocellular carcinoma (HCC) patients with tumor thrombus extended through the major hepatic veins and inferior vena cava into the right atrium (RA) are rare, and most cases are considered as the advanced stage with a poor prognosis.We report a case...περισσότερα »
Alexandros G. SfakianakisστοHead and NeckΠριν από 3 ώρες
[image: http:--pt.wkhealth.com-pt-pt-core-templa] [image: http:--http://ift.tt/1Fkw4zC] Related Articles *Hepatocellular Carcinoma With Tumor Thrombus Occupying the Right Atrium and Portal Vein: A Case Report and Literature Review.* Medicine (Baltimore). 2015 Aug;94(34):e1049 Authors: Luo X, Zhang B, Dong S, Zhang B, Chen X Abstract Hepatocellular carcinoma (HCC) patients with tumor thrombus extended through the major hepatic veins and inferior vena cava into the right atrium (RA) are rare, and most cases are considered as the advanced stage with a poor prognosis.We report a case...περισσότερα »
High-risk human papillomavirus infection involving multiple anatomic sites of the female lower genital tract: a multiplex real-time polymerase chain reaction-based study.
Alexandros G. SfakianakisστοHead and NeckΠριν από 3 ώρες
[image: http:--linkinghub.elsevier.com-ihub-imag] Related Articles *High-risk human papillomavirus infection involving multiple anatomic sites of the female lower genital tract: a multiplex real-time polymerase chain reaction-based study.* Hum Pathol. 2015 Sep;46(9):1376-81 Authors: Hui Y, Manna P, Ou JJ, Kerley S, Zhang C, Sung CJ, Lawrence WD, Quddus MR Abstract High-risk human papillomavirus infection usually is seen at one anatomic site in an individual. Rarely, infection at multiple anatomic sites of the female lower genital tract in the same individual is encountered either... περισσότερα »
Alexandros G. SfakianakisστοHead and NeckΠριν από 3 ώρες
[image: http:--linkinghub.elsevier.com-ihub-imag] Related Articles *High-risk human papillomavirus infection involving multiple anatomic sites of the female lower genital tract: a multiplex real-time polymerase chain reaction-based study.* Hum Pathol. 2015 Sep;46(9):1376-81 Authors: Hui Y, Manna P, Ou JJ, Kerley S, Zhang C, Sung CJ, Lawrence WD, Quddus MR Abstract High-risk human papillomavirus infection usually is seen at one anatomic site in an individual. Rarely, infection at multiple anatomic sites of the female lower genital tract in the same individual is encountered either... περισσότερα »
[Embryonal paratesticular rhabdomyosarcoma: a case report and a literature review].
Alexandros G. SfakianakisστοHead and NeckΠριν από 3 ώρες
[image: http:--linkinghub.elsevier.com-ihub-imag] Related Articles *[Embryonal paratesticular rhabdomyosarcoma: a case report and a literature review].* Cancer Radiother. 2015 Aug;19(5):334-6 Authors: Ghorbal L, Abid W, Elloumi F, Sallemi T, Frikha M, Daoud J Abstract Paratesticular rhabdomyosarcoma is a rare tumor. Multimodality treatment should involve surgery, radiotherapy and chemotherapy, which are indicated according to risk groups. Risk group stratification depends on pretreatment staging and definitive histology. Patients older than 10years or those with suspected lymph n... περισσότερα »
Alexandros G. SfakianakisστοHead and NeckΠριν από 3 ώρες
[image: http:--linkinghub.elsevier.com-ihub-imag] Related Articles *[Embryonal paratesticular rhabdomyosarcoma: a case report and a literature review].* Cancer Radiother. 2015 Aug;19(5):334-6 Authors: Ghorbal L, Abid W, Elloumi F, Sallemi T, Frikha M, Daoud J Abstract Paratesticular rhabdomyosarcoma is a rare tumor. Multimodality treatment should involve surgery, radiotherapy and chemotherapy, which are indicated according to risk groups. Risk group stratification depends on pretreatment staging and definitive histology. Patients older than 10years or those with suspected lymph n... περισσότερα »
Expression of adhesion molecules and epithelial-mesenchymal transition factors in medullary carcinoma of the colorectum.
Alexandros G. SfakianakisστοHead and NeckΠριν από 3 ώρες
[image: http:--linkinghub.elsevier.com-ihub-imag] Related Articles *Expression of adhesion molecules and epithelial-mesenchymal transition factors in medullary carcinoma of the colorectum.* Hum Pathol. 2015 Sep;46(9):1257-66 Authors: Takahashi S, Kohashi K, Yamamoto H, Hirahashi M, Kumagai R, Takizawa N, Nakamura K, Maehara Y, Tanaka M, Takayanagi R, Oda Y Abstract Medullary carcinoma (MC) of the colorectum is known as a rare variant with favorable prognosis despite its poorly differentiated morphology. The mechanism of its favorable behavior has been unclear. Here, we compared th... περισσότερα »
Alexandros G. SfakianakisστοHead and NeckΠριν από 3 ώρες
[image: http:--linkinghub.elsevier.com-ihub-imag] Related Articles *Expression of adhesion molecules and epithelial-mesenchymal transition factors in medullary carcinoma of the colorectum.* Hum Pathol. 2015 Sep;46(9):1257-66 Authors: Takahashi S, Kohashi K, Yamamoto H, Hirahashi M, Kumagai R, Takizawa N, Nakamura K, Maehara Y, Tanaka M, Takayanagi R, Oda Y Abstract Medullary carcinoma (MC) of the colorectum is known as a rare variant with favorable prognosis despite its poorly differentiated morphology. The mechanism of its favorable behavior has been unclear. Here, we compared th... περισσότερα »
Glandular differentiation in dedifferentiated chondrosarcoma: molecular evidence of a rare phenomenon.
Alexandros G. SfakianakisστοHead and NeckΠριν από 3 ώρες
[image: http:--linkinghub.elsevier.com-ihub-imag] Related Articles *Glandular differentiation in dedifferentiated chondrosarcoma: molecular evidence of a rare phenomenon.* Hum Pathol. 2015 Sep;46(9):1398-404 Authors: Jour G, Liu Y, Ricciotti R, Pritchard C, Hoch BL Abstract Epithelial glandular differentiation in dedifferentiated chondrosarcoma has not been described. Our patient was a 64-year-old man with a history of prostate cancer status post-radiation and hormonal therapy. On screening bone scan, he was found to have increased uptake in his right femoral shaft. Biopsy reveal...περισσότερα »
Alexandros G. SfakianakisστοHead and NeckΠριν από 3 ώρες
[image: http:--linkinghub.elsevier.com-ihub-imag] Related Articles *Glandular differentiation in dedifferentiated chondrosarcoma: molecular evidence of a rare phenomenon.* Hum Pathol. 2015 Sep;46(9):1398-404 Authors: Jour G, Liu Y, Ricciotti R, Pritchard C, Hoch BL Abstract Epithelial glandular differentiation in dedifferentiated chondrosarcoma has not been described. Our patient was a 64-year-old man with a history of prostate cancer status post-radiation and hormonal therapy. On screening bone scan, he was found to have increased uptake in his right femoral shaft. Biopsy reveal...περισσότερα »
[Evolution of the management of pediatric and adult medulloblastoma].
Alexandros G. SfakianakisστοHead and NeckΠριν από 3 ώρες
[image: http:--linkinghub.elsevier.com-ihub-imag] Related Articles *[Evolution of the management of pediatric and adult medulloblastoma].* Cancer Radiother. 2015 Aug;19(5):347-57; quiz 358-9, 362 Authors: Vigneron C, Entz-Werlé N, Lutz P, Spiegel A, Jannier S, Helfre S, Alapetite C, Coca A, Kehrli P, Noël G Abstract Medulloblastoma are cerebellar tumours belonging to the group of primitive neuroectodermal tumours (PNET) and are the most common malignant brain tumours of childhood. These tumours are rare and heterogeneous, requiring some multicentric prospective studies and multidi...περισσότερα »
Alexandros G. SfakianakisστοHead and NeckΠριν από 3 ώρες
[image: http:--linkinghub.elsevier.com-ihub-imag] Related Articles *[Evolution of the management of pediatric and adult medulloblastoma].* Cancer Radiother. 2015 Aug;19(5):347-57; quiz 358-9, 362 Authors: Vigneron C, Entz-Werlé N, Lutz P, Spiegel A, Jannier S, Helfre S, Alapetite C, Coca A, Kehrli P, Noël G Abstract Medulloblastoma are cerebellar tumours belonging to the group of primitive neuroectodermal tumours (PNET) and are the most common malignant brain tumours of childhood. These tumours are rare and heterogeneous, requiring some multicentric prospective studies and multidi...περισσότερα »
Carney complex: an update.
Alexandros G. SfakianakisστοHead and NeckΠριν από 3 ώρες
[image: http:--highwire.stanford.edu-icons-exter] Related Articles *Carney complex: an update.* Eur J Endocrinol. 2015 Oct;173(4):M85-97 Authors: Correa R, Salpea P, Stratakis CA Abstract Carney complex (CNC) is a rare autosomal dominant syndrome, characterized by pigmented lesions of the skin and mucosa, cardiac, cutaneous and other myxomas and multiple endocrine tumors. The disease is caused by inactivating mutations or large deletions of the PRKAR1A gene located at 17q22-24 coding for the regulatory subunit type I alpha of protein kinase A (PKA) gene. Most recently, components... περισσότερα »
Alexandros G. SfakianakisστοHead and NeckΠριν από 3 ώρες
[image: http:--highwire.stanford.edu-icons-exter] Related Articles *Carney complex: an update.* Eur J Endocrinol. 2015 Oct;173(4):M85-97 Authors: Correa R, Salpea P, Stratakis CA Abstract Carney complex (CNC) is a rare autosomal dominant syndrome, characterized by pigmented lesions of the skin and mucosa, cardiac, cutaneous and other myxomas and multiple endocrine tumors. The disease is caused by inactivating mutations or large deletions of the PRKAR1A gene located at 17q22-24 coding for the regulatory subunit type I alpha of protein kinase A (PKA) gene. Most recently, components... περισσότερα »
Pure versus combined Merkel cell carcinomas: immunohistochemical evaluation of cellular proteins (p53, Bcl-2, and c-kit) reveals significant overexpression of p53 in combined tumors.
Alexandros G. SfakianakisστοHead and NeckΠριν από 3 ώρες
[image: http:--linkinghub.elsevier.com-ihub-imag] Related Articles *Pure versus combined Merkel cell carcinomas: immunohistochemical evaluation of cellular proteins (p53, Bcl-2, and c-kit) reveals significant overexpression of p53 in combined tumors.* Hum Pathol. 2015 Sep;46(9):1290-6 Authors: Lai JH, Fleming KE, Ly TY, Pasternak S, Godlewski M, Doucette S, Walsh NM Abstract Merkel cell polyomavirus is of oncogenic significance in approximately 80% of Merkel cell carcinomas. Morphological subcategories of the tumor differ in regard to viral status, the rare combined type being un...περισσότερα »
Alexandros G. SfakianakisστοHead and NeckΠριν από 3 ώρες
[image: http:--linkinghub.elsevier.com-ihub-imag] Related Articles *Pure versus combined Merkel cell carcinomas: immunohistochemical evaluation of cellular proteins (p53, Bcl-2, and c-kit) reveals significant overexpression of p53 in combined tumors.* Hum Pathol. 2015 Sep;46(9):1290-6 Authors: Lai JH, Fleming KE, Ly TY, Pasternak S, Godlewski M, Doucette S, Walsh NM Abstract Merkel cell polyomavirus is of oncogenic significance in approximately 80% of Merkel cell carcinomas. Morphological subcategories of the tumor differ in regard to viral status, the rare combined type being un...περισσότερα »
Impact of Chromogranin A deficiency on catecholamine storage, catecholamine granule morphology and chromaffin cell energy metabolism in vivo
Alexandros G. SfakianakisστοCell and Tissue Research by Alexandros G. SfakianakisΠριν από 3 ώρες
Abstract Chromogranin A (CgA) is a prohormone and granulogenic factor in neuroendocrine tissues with a regulated secretory pathway. The impact of CgA depletion on secretory granule formation has been previously demonstrated in cell culture. However, studies linking the structural effects of CgA deficiency with secretory performance and cell metabolism in the adrenomedullary chromaffin cells in vivo have not previously been reported. Adrenomedullary content of the secreted adrenal catecholamines norepinephrine (NE) and epinephrine (EPI) was decreased 30–40 % in *Chga*-KO mice. Quan...περισσότερα »
Alexandros G. SfakianakisστοCell and Tissue Research by Alexandros G. SfakianakisΠριν από 3 ώρες
Abstract Chromogranin A (CgA) is a prohormone and granulogenic factor in neuroendocrine tissues with a regulated secretory pathway. The impact of CgA depletion on secretory granule formation has been previously demonstrated in cell culture. However, studies linking the structural effects of CgA deficiency with secretory performance and cell metabolism in the adrenomedullary chromaffin cells in vivo have not previously been reported. Adrenomedullary content of the secreted adrenal catecholamines norepinephrine (NE) and epinephrine (EPI) was decreased 30–40 % in *Chga*-KO mice. Quan...περισσότερα »
Acknowledgement to reviewers
Alexandros G. SfakianakisστοCell and Tissue Research by Alexandros G. SfakianakisΠριν από 3 ώρες
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Alexandros G. SfakianakisστοCell and Tissue Research by Alexandros G. SfakianakisΠριν από 3 ώρες
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Tyrosine hydroxylase immunoreactivity is common in the enteric nervous system in teleosts
Alexandros G. SfakianakisστοCell and Tissue Research by Alexandros G. SfakianakisΠριν από 3 ώρες
Abstract Tyrosine hydroxylase (TH) is the rate-limiting enzyme in the synthesis of catecholamines and TH immunoreactivity is indicative of cells synthesising either adrenaline/noradrenaline or dopamine. In this study, the distribution of TH immunoreactivity was examined in two distantly related teleost species, zebrafish (*Danio rerio*) and shorthorn sculpin (*Myoxocephalus scorpius*). In both species, TH-immunoreactive nerve cell bodies and varicose nerve fibres were common in the myenteric plexus of the intestine. However, no TH-immunoreactive nerve cell bodies were seen in the s... περισσότερα »
Alexandros G. SfakianakisστοCell and Tissue Research by Alexandros G. SfakianakisΠριν από 3 ώρες
Abstract Tyrosine hydroxylase (TH) is the rate-limiting enzyme in the synthesis of catecholamines and TH immunoreactivity is indicative of cells synthesising either adrenaline/noradrenaline or dopamine. In this study, the distribution of TH immunoreactivity was examined in two distantly related teleost species, zebrafish (*Danio rerio*) and shorthorn sculpin (*Myoxocephalus scorpius*). In both species, TH-immunoreactive nerve cell bodies and varicose nerve fibres were common in the myenteric plexus of the intestine. However, no TH-immunoreactive nerve cell bodies were seen in the s... περισσότερα »
To serve and to protect: the role of decidual innate immune cells on human pregnancy
Alexandros G. SfakianakisστοCell and Tissue Research by Alexandros G. SfakianakisΠριν από 3 ώρες
Abstract The maternal–fetal interface undergoes dynamic changes that promote successful development of the embryo/fetal allograft during pregnancy. This immune privilege of the conceptus is mediated through local and systemic cellular responses. In species in which endometrial decidualization accompanies pregnancy, unique immune cell niches are found. Many studies have addressed the enigmatic roles of uterine (u)NK cells as killers and helpers because they are frequently found in the uterine lining and decidua of normal and pathological pregnancies. Accumulating evidence indicates ...περισσότερα »
Alexandros G. SfakianakisστοCell and Tissue Research by Alexandros G. SfakianakisΠριν από 3 ώρες
Abstract The maternal–fetal interface undergoes dynamic changes that promote successful development of the embryo/fetal allograft during pregnancy. This immune privilege of the conceptus is mediated through local and systemic cellular responses. In species in which endometrial decidualization accompanies pregnancy, unique immune cell niches are found. Many studies have addressed the enigmatic roles of uterine (u)NK cells as killers and helpers because they are frequently found in the uterine lining and decidua of normal and pathological pregnancies. Accumulating evidence indicates ...περισσότερα »
CXCL10/CXCR3 signaling mediates inhibitory action by interferon-gamma on CRF-stimulated adrenocorticotropic hormone (ACTH) release
Alexandros G. SfakianakisστοCell and Tissue Research by Alexandros G. SfakianakisΠριν από 3 ώρες
Abstract Secretion of hormones by the anterior pituitary gland can be stimulated or inhibited by paracrine factors that are produced during inflammatory reactions. The inflammation cytokine interferon-gamma (IFN-γ) is known to inhibit corticotropin-releasing factor (CRF)-stimulated adrenocorticotropin (ACTH) release but its signaling mechanism is not yet known. Using rat anterior pituitary, we previously demonstrated that the CXC chemokine ligand 10 (CXCL10), known as interferon-γ (IFN-γ) inducible protein 10 kDa, is expressed in dendritic cell-like S100β protein-positive (DC-like ...περισσότερα »
Alexandros G. SfakianakisστοCell and Tissue Research by Alexandros G. SfakianakisΠριν από 3 ώρες
Abstract Secretion of hormones by the anterior pituitary gland can be stimulated or inhibited by paracrine factors that are produced during inflammatory reactions. The inflammation cytokine interferon-gamma (IFN-γ) is known to inhibit corticotropin-releasing factor (CRF)-stimulated adrenocorticotropin (ACTH) release but its signaling mechanism is not yet known. Using rat anterior pituitary, we previously demonstrated that the CXC chemokine ligand 10 (CXCL10), known as interferon-γ (IFN-γ) inducible protein 10 kDa, is expressed in dendritic cell-like S100β protein-positive (DC-like ...περισσότερα »
Survival and prognostic factors of anaplastic thyroid carcinoma.
Alexandros G. SfakianakisστοHead and NeckΠριν από 3 ώρες
Related Articles *Survival and prognostic factors of anaplastic thyroid carcinoma.* Acta Chir Belg. 2015 Jan-Feb;115:62-7 Authors: Paunovic IR, Sipetic SB, Zoric GV, Diklic AD, Savic DV, Marinkovic J, Zivaljevic VR Abstract BACKGROUND: Anaplastic thyroid carcinoma (ATC) is relatively rare and represents one of the most aggressive tumours with poor prognosis, despite therapy. The aim of the study was to analyse demographic and clinical characteristics of ATC patients, and to identify survival rates and prognostic factors. METHODS: In a retrospective study (1995-2005) ATC was found...περισσότερα »
Alexandros G. SfakianakisστοHead and NeckΠριν από 3 ώρες
Related Articles *Survival and prognostic factors of anaplastic thyroid carcinoma.* Acta Chir Belg. 2015 Jan-Feb;115:62-7 Authors: Paunovic IR, Sipetic SB, Zoric GV, Diklic AD, Savic DV, Marinkovic J, Zivaljevic VR Abstract BACKGROUND: Anaplastic thyroid carcinoma (ATC) is relatively rare and represents one of the most aggressive tumours with poor prognosis, despite therapy. The aim of the study was to analyse demographic and clinical characteristics of ATC patients, and to identify survival rates and prognostic factors. METHODS: In a retrospective study (1995-2005) ATC was found...περισσότερα »
Single-centre 20-year experience with surgical treatment of thymic tumours.
Alexandros G. SfakianakisστοHead and NeckΠριν από 3 ώρες
Related Articles *Single-centre 20-year experience with surgical treatment of thymic tumours.* Acta Chir Belg. 2015 Jan-Feb;115:52-61 Authors: Viskens S, Van Veer H, Tousseyn T, Coosemans W, Decaluwe H, Nafteux P, De Lyen P, Schoffski P, De Ruysscher D, Van Raemdonck D Abstract BACKGROUND: Large single-centre institutional series on thymic tumours are rare. Complete resection remains the mainstay of successful treatment. Characteristics and survival were reviewed in all patients treated between 1993-2013. METHODS: Hospital databases revealed 134 patients with pathologically-prov... περισσότερα »
Alexandros G. SfakianakisστοHead and NeckΠριν από 3 ώρες
Related Articles *Single-centre 20-year experience with surgical treatment of thymic tumours.* Acta Chir Belg. 2015 Jan-Feb;115:52-61 Authors: Viskens S, Van Veer H, Tousseyn T, Coosemans W, Decaluwe H, Nafteux P, De Lyen P, Schoffski P, De Ruysscher D, Van Raemdonck D Abstract BACKGROUND: Large single-centre institutional series on thymic tumours are rare. Complete resection remains the mainstay of successful treatment. Characteristics and survival were reviewed in all patients treated between 1993-2013. METHODS: Hospital databases revealed 134 patients with pathologically-prov... περισσότερα »
Induction chemotherapy followed by concurrent radio-chemotherapy versus concurrent radio-chemotherapy alone as treatment of locally advanced squamous cell carcinoma of the head and neck (HNSCC): A meta-analysis of randomized trials
Alexandros G. SfakianakisστοΘεραπείαΠριν από 3 ώρες
Publication date: Available online 14 November 2015 *Source:*Radiotherapy and Oncology Author(s): Wilfried Budach, Edwin Bölke, Kai Kammers, Peter Arne Gerber, Klaus Orth, Stephan Gripp, Christiane Matuschek BackgroundInduction chemotherapy with docetaxel, cisplatin and 5 FU (TPF) before radiotherapy (RT) or radio-chemotherapy (RT-CHX) has been shown to improve overall survival (OS) compared to induction chemotherapy with cisplatin and 5 FU in locally advanced squamous cell carcinoma of the head and neck (HNSCC). Whether TPF induction before RT-CHX improves clinical outcome in compa... περισσότερα »
Alexandros G. SfakianakisστοΘεραπείαΠριν από 3 ώρες
Publication date: Available online 14 November 2015 *Source:*Radiotherapy and Oncology Author(s): Wilfried Budach, Edwin Bölke, Kai Kammers, Peter Arne Gerber, Klaus Orth, Stephan Gripp, Christiane Matuschek BackgroundInduction chemotherapy with docetaxel, cisplatin and 5 FU (TPF) before radiotherapy (RT) or radio-chemotherapy (RT-CHX) has been shown to improve overall survival (OS) compared to induction chemotherapy with cisplatin and 5 FU in locally advanced squamous cell carcinoma of the head and neck (HNSCC). Whether TPF induction before RT-CHX improves clinical outcome in compa... περισσότερα »
A lack of “glue” misplaces Rab27A to cause islet dysfunction in diabetes
Alexandros G. SfakianakisστοΠαθολοΑνατομίαΠριν από 4 ώρες
Abstract Glucose-stimulated insulin secretion (GSIS) involves interplay between metabolic and cationic events. Several lines of evidence suggests novel regulatory roles for small G proteins (Rac1, Cdc42, Rab27A) in cytoskeletal remodeling and docking of insulin granules on the plasma membrane for insulin secretion. Emerging evidence implicates novel roles for post-translational prenylation (farnesylation and geranylgeranylation) of G proteins for their targeting to appropriate membranous compartments. While several recent studies were focused on prenylating enzymes in the islet β-... περισσότερα »
Alexandros G. SfakianakisστοΠαθολοΑνατομίαΠριν από 4 ώρες
Abstract Glucose-stimulated insulin secretion (GSIS) involves interplay between metabolic and cationic events. Several lines of evidence suggests novel regulatory roles for small G proteins (Rac1, Cdc42, Rab27A) in cytoskeletal remodeling and docking of insulin granules on the plasma membrane for insulin secretion. Emerging evidence implicates novel roles for post-translational prenylation (farnesylation and geranylgeranylation) of G proteins for their targeting to appropriate membranous compartments. While several recent studies were focused on prenylating enzymes in the islet β-... περισσότερα »
Pattern of emergency room mortality among road traffic crash victims
Alexandros G. SfakianakisστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 4 ώρες
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Alexandros G. SfakianakisστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 4 ώρες
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Meta-analysis of colloids versus crystalloids in critically ill, trauma and surgical patients
Alexandros G. SfakianakisστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 4 ώρες
British Journal of Surgery from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1S0PfH1 via IFTTT
Alexandros G. SfakianakisστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 4 ώρες
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Emergency department visits for self-inflicted injuries in adolescents
Alexandros G. SfakianakisστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 4 ώρες
The Journal of Emergency Medicine from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1S0PfqL via IFTTT
Alexandros G. SfakianakisστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 4 ώρες
The Journal of Emergency Medicine from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1S0PfqL via IFTTT
Effect of reduction in the use of computed tomography on clinical outcomes of appendicitis
Alexandros G. SfakianakisστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 4 ώρες
The Journal of Emergency Medicine from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1S0PhPg via IFTTT
Alexandros G. SfakianakisστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 4 ώρες
The Journal of Emergency Medicine from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1S0PhPg via IFTTT
Characterization of the inflammatory cell infiltrate and expression of costimulatory molecules in chronic echinococcus granulosus infection of the human liver
Alexandros G. SfakianakisστοΛοίμωξηΠριν από 5 ώρες
Background: The local immune responses to chronic echinococcal infections in various organs are largely unknown. Since the liver is the most frequently involved organ in such infections in human we aimed to characterize the inflammatory as well as immune cell infiltrate around hydatid cysts in the liver and compared to common inflammatory processes of the liver.MethodSurgical samples from the liver of 21 cystic echinococcosis (CE) patients were studied and the distribution of different types of inflammatory and immune cells were determined by immunohistochemistry. Furthermore, exp...περισσότερα »
Alexandros G. SfakianakisστοΛοίμωξηΠριν από 5 ώρες
Background: The local immune responses to chronic echinococcal infections in various organs are largely unknown. Since the liver is the most frequently involved organ in such infections in human we aimed to characterize the inflammatory as well as immune cell infiltrate around hydatid cysts in the liver and compared to common inflammatory processes of the liver.MethodSurgical samples from the liver of 21 cystic echinococcosis (CE) patients were studied and the distribution of different types of inflammatory and immune cells were determined by immunohistochemistry. Furthermore, exp...περισσότερα »
A novel CHST3 allele associated with Spondyloepiphyseal dysplasia and hearing loss in Pakistani kindred
Alexandros G. SfakianakisστοEvolution of a geneΠριν από 5 ώρες
Abstract Skeletal dysplasias are highly heterogeneous disorders composed of 40 clinical sub-types that are part of 456 well-delineated syndromes in humans. Here, we enrolled consanguineous kindred from a remote area of Sindh province of Pakistan, with fourteen affected individuals suffering with short stature, kyphoscoliosis, joint dislocations, clubfoot, heart valve anomalies and progressive bilateral mixed hearing loss. To identify pathogenic variants in this family, whole exome sequencing (WES) was performed in one affected and one normal individual, which revealed a novel tran... περισσότερα »
Alexandros G. SfakianakisστοEvolution of a geneΠριν από 5 ώρες
Abstract Skeletal dysplasias are highly heterogeneous disorders composed of 40 clinical sub-types that are part of 456 well-delineated syndromes in humans. Here, we enrolled consanguineous kindred from a remote area of Sindh province of Pakistan, with fourteen affected individuals suffering with short stature, kyphoscoliosis, joint dislocations, clubfoot, heart valve anomalies and progressive bilateral mixed hearing loss. To identify pathogenic variants in this family, whole exome sequencing (WES) was performed in one affected and one normal individual, which revealed a novel tran... περισσότερα »
Muscle hypertrophy as the presenting sign in a patient with a complete FHL1 deletion
Alexandros G. SfakianakisστοEvolution of a geneΠριν από 5 ώρες
Abstract Four and a half LIM protein 1 (FHL1/SLIM1), has recently been identified as the causative gene mutated in four distinct diseases affecting skeletal muscle that have overlapping features, including reducing body myopathy, X-linked myopathy, X-linked dominant scapuloperoneal myopathy and Emery–Dreifuss muscular dystrophy (EDMD). FHL1 localizes to the sarcomere and the sarcolemma and is believed to participate in muscle growth and differentiation as well as in sarcomere assembly. We describe in this case report a boy with a deletion of the entire *FHL1* gene who is now 15 yea...περισσότερα »
Alexandros G. SfakianakisστοEvolution of a geneΠριν από 5 ώρες
Abstract Four and a half LIM protein 1 (FHL1/SLIM1), has recently been identified as the causative gene mutated in four distinct diseases affecting skeletal muscle that have overlapping features, including reducing body myopathy, X-linked myopathy, X-linked dominant scapuloperoneal myopathy and Emery–Dreifuss muscular dystrophy (EDMD). FHL1 localizes to the sarcomere and the sarcolemma and is believed to participate in muscle growth and differentiation as well as in sarcomere assembly. We describe in this case report a boy with a deletion of the entire *FHL1* gene who is now 15 yea...περισσότερα »
JP-HHT phenotype in Danish patients with SMAD4 mutations
Alexandros G. SfakianakisστοEvolution of a geneΠριν από 5 ώρες
Abstract Patients with germline mutations in *SMAD4* can present symptoms of both Juvenile Polyposis Syndrome (JPS) and Hereditary Hemorrhagic Telangiectasia (HHT): the JP-HHT syndrome. The full phenotypic picture of this syndrome is only just emerging. We describe the clinical characteristics of 14 patients with *SMAD4*-mutations. The study was a retrospective, register-based study. *SMAD4* mutations carriers were identified through the Danish HHT-registry, the genetic laboratories - and the genetic departments in Denmark. The medical files from relevant departments were reviewed ... περισσότερα »
Alexandros G. SfakianakisστοEvolution of a geneΠριν από 5 ώρες
Abstract Patients with germline mutations in *SMAD4* can present symptoms of both Juvenile Polyposis Syndrome (JPS) and Hereditary Hemorrhagic Telangiectasia (HHT): the JP-HHT syndrome. The full phenotypic picture of this syndrome is only just emerging. We describe the clinical characteristics of 14 patients with *SMAD4*-mutations. The study was a retrospective, register-based study. *SMAD4* mutations carriers were identified through the Danish HHT-registry, the genetic laboratories - and the genetic departments in Denmark. The medical files from relevant departments were reviewed ... περισσότερα »
Role of Calprotectin as a Modulator of the IL27-Mediated Proinflammatory Effect on Endothelial Cells
Alexandros G. SfakianakisστοΛοίμωξηΠριν από 6 ώρες
An underlying endothelial dysfunction plays a fundamental role in the pathogenesis of cardiovascular events and is the central feature of atherosclerosis. The protein-based communication between leukocytes and inflamed endothelial cells leading to diapedesis has been largely investigated and several key players such as IL6, TNFα, or the damage associated molecular pattern molecule (DAMP) calprotectin are now well identified. However, regarding cytokine IL27, the controversial current knowledge about its inflammatory role and the involved regulatory elements requires clarification.... περισσότερα »
Alexandros G. SfakianakisστοΛοίμωξηΠριν από 6 ώρες
An underlying endothelial dysfunction plays a fundamental role in the pathogenesis of cardiovascular events and is the central feature of atherosclerosis. The protein-based communication between leukocytes and inflamed endothelial cells leading to diapedesis has been largely investigated and several key players such as IL6, TNFα, or the damage associated molecular pattern molecule (DAMP) calprotectin are now well identified. However, regarding cytokine IL27, the controversial current knowledge about its inflammatory role and the involved regulatory elements requires clarification.... περισσότερα »
Dysuria, Urinary Retention, and Inguinal Pain as Manifestation of Sacral Bannwarth Syndrome
Alexandros G. SfakianakisστοΟγκολογίαΠριν από 6 ώρες
Only few cases with sacral radiculitis due to infection with Borrelia burgdorferi leading to neurogenic urinary dysfunction have been reported. A 57-year-old male developed urethral pain and urinary retention, requiring permanent catheterization. Extensive urological investigations did not reveal a specific cause, which was why neurogenic bladder dysfunction was suspected. Neurologic exam revealed only mildly reduced tendon reflexes. Cerebral and spinal MRI were noninformative. CSF investigations, however, revealed pleocytosis, elevated protein, and antibodies against Borrelia bur... περισσότερα »
Alexandros G. SfakianakisστοΟγκολογίαΠριν από 6 ώρες
Only few cases with sacral radiculitis due to infection with Borrelia burgdorferi leading to neurogenic urinary dysfunction have been reported. A 57-year-old male developed urethral pain and urinary retention, requiring permanent catheterization. Extensive urological investigations did not reveal a specific cause, which was why neurogenic bladder dysfunction was suspected. Neurologic exam revealed only mildly reduced tendon reflexes. Cerebral and spinal MRI were noninformative. CSF investigations, however, revealed pleocytosis, elevated protein, and antibodies against Borrelia bur... περισσότερα »
Cancer Research Cancer Res Table of Contents for November 15, 2015 Vol. 75, No. 22
Αλέξανδρος ΣφακιανάκηςστοMedicine by Sfakianakis G. AlexandrosΠριν από 6 ώρες
[image: American Association for Cancer Research] [image: Cancer Research] Home OnlineFirst Current Issue Past Issues Subscriptions Alerts Feedback AACR Publications AACR Home ------------------------------ [image: XFp Cell Energy Phenotype Test] ******************************************************************* ADVERTISEMENT: The XFp Cell Energy Phenotype Test is the only single assay that can simultaneously report both mitochondrial respiration and glycolytic activity in less than an hour. The XF Cell Energy Phenotype Test is a reagent kit and analysis method that allows y... περισσότερα »
Αλέξανδρος ΣφακιανάκηςστοMedicine by Sfakianakis G. AlexandrosΠριν από 6 ώρες
[image: American Association for Cancer Research] [image: Cancer Research] Home OnlineFirst Current Issue Past Issues Subscriptions Alerts Feedback AACR Publications AACR Home ------------------------------ [image: XFp Cell Energy Phenotype Test] ******************************************************************* ADVERTISEMENT: The XFp Cell Energy Phenotype Test is the only single assay that can simultaneously report both mitochondrial respiration and glycolytic activity in less than an hour. The XF Cell Energy Phenotype Test is a reagent kit and analysis method that allows y... περισσότερα »
Selective loss of alpha motor neurons with sparing of gamma motor neurons and spinal cord cholinergic neurons in a mouse model of spinal muscular atrophy
Alexandros G. SfakianakisστοΠαθολοΑνατομίαΠριν από 7 ώρες
Abstract Spinal muscular atrophy (SMA) is a neuromuscular disease characterised primarily by loss of lower motor neurons from the ventral grey horn of the spinal cord and proximal muscle atrophy. Recent experiments utilising mouse models of SMA have demonstrated that not all motor neurons are equally susceptible to the disease, revealing that other populations of neurons can also be affected. Here, we have extended investigations of selective vulnerability of neuronal populations in the spinal cord of SMA mice to include comparative assessments of alpha motor neuron (α-MN) and gamm... περισσότερα »
Alexandros G. SfakianakisστοΠαθολοΑνατομίαΠριν από 7 ώρες
Abstract Spinal muscular atrophy (SMA) is a neuromuscular disease characterised primarily by loss of lower motor neurons from the ventral grey horn of the spinal cord and proximal muscle atrophy. Recent experiments utilising mouse models of SMA have demonstrated that not all motor neurons are equally susceptible to the disease, revealing that other populations of neurons can also be affected. Here, we have extended investigations of selective vulnerability of neuronal populations in the spinal cord of SMA mice to include comparative assessments of alpha motor neuron (α-MN) and gamm... περισσότερα »
Morphology and function of the palatal dentition in Choristodera
Alexandros G. SfakianakisστοΠαθολοΑνατομίαΠριν από 7 ώρες
Abstract Choristoderes are a group of extinct freshwater reptiles that were distributed throughout Laurasia from the Middle Jurassic to the Miocene. They are inferred to have had a lifestyle similar to that of extant gavialid crocodiles, but they differed from crocodiles in retaining an extensive palatal dentition. All choristoderes had teeth on the vomers, palatines and pterygoids, and teeth are rarely present on the parasphenoid. Palatal teeth are conical, as in the marginal dentition, and form longitudinal and transverse rows. Detailed examination of different genera shows that... περισσότερα »
Alexandros G. SfakianakisστοΠαθολοΑνατομίαΠριν από 7 ώρες
Abstract Choristoderes are a group of extinct freshwater reptiles that were distributed throughout Laurasia from the Middle Jurassic to the Miocene. They are inferred to have had a lifestyle similar to that of extant gavialid crocodiles, but they differed from crocodiles in retaining an extensive palatal dentition. All choristoderes had teeth on the vomers, palatines and pterygoids, and teeth are rarely present on the parasphenoid. Palatal teeth are conical, as in the marginal dentition, and form longitudinal and transverse rows. Detailed examination of different genera shows that... περισσότερα »
Morphological analysis of the urethral muscle of the male pig with relevance to urinary continence and micturition
Alexandros G. SfakianakisστοΠαθολοΑνατομίαΠριν από 7 ώρες
Abstract To investigate whether the pig could be considered a suitable model to study lower urinary tract function and dysfunction, the pelvic urethra of 24 slaughtered male pigs were collected, and the associated muscles were macroscopically, histologically and histochemically analyzed. In cross-sections of the urethra, a muscular complex composed of an inner layer of smooth muscle and an outer layer of striated muscle that are not separated by fascial planes was observed. A tunica muscularis, composed of differently oriented smooth muscle bundles, is only evident in the proximal ... περισσότερα »
Alexandros G. SfakianakisστοΠαθολοΑνατομίαΠριν από 7 ώρες
Abstract To investigate whether the pig could be considered a suitable model to study lower urinary tract function and dysfunction, the pelvic urethra of 24 slaughtered male pigs were collected, and the associated muscles were macroscopically, histologically and histochemically analyzed. In cross-sections of the urethra, a muscular complex composed of an inner layer of smooth muscle and an outer layer of striated muscle that are not separated by fascial planes was observed. A tunica muscularis, composed of differently oriented smooth muscle bundles, is only evident in the proximal ... περισσότερα »
