Neurotization of the radial forearm free flap improves swallowing outcomes in hemiglossectomy defects

alexandrossfakianakis shared this article with you from Inoreader Neurotization of the radial forearm free flap improves swallowing outcomes in hemiglossectomy defects via Head & Neck Abstract Background We examined the effect of free tissue neurotization on speech and swallowing outcomes for patients undergoing reconstruction of hemiglossectomy defects with a radial forearm free flap (RFFF). Methods A retrospective study was performed in patients with oral cavity squamous cell carcinoma undergoing a hemiglossectomy and reconstruction with a RFFF. Functional outcomes including nutritional mode, range of liquids and solids, and speech understandability were analyzed 1-year post-treatment. Results Eighty-four patients were included in this analysis, 41 of whom had neurotized flaps (49%). No significant differences in demographic or clinical variables were seen between the neurotized and non-neurotized groups. On multivariate analysis controlling for BMI, flap area, and N-classification, patients with neurotized flaps were significantly more likely to have normal range of liquids and solids and less likely to have a G-tube. Conclusions Neurotization of RFFF reconstructing hemiglossectomy defects results in decreased G-tube dependence and improved range of liquids and solids. View on Web

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Role of mechano-sensitive non-coding RNAs in bone remodeling of orthodontic tooth movement: recent advances

alexandrossfakianakis shared this article with you from Inoreader Role of mechano-sensitive non-coding RNAs in bone remodeling of orthodontic tooth movement: recent advances via Progress in Orthodontics - Latest Articles Orthodontic tooth movement relies on bone remodeling and periodontal tissue regeneration in response to the complicated mechanical cues on the compressive and tensive side. In general, mechanical stimulus regu... View on Web

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Managing Oromandibular Hardware Failure after Free Flap Surgery

alexandrossfakianakis shared this article with you from Inoreader Managing Oromandibular Hardware Failure after Free Flap Surgery via Seminars in Plastic Surgery Semin Plast Surg DOI: 10.1055/s-0042-1760289 Hardware failure after oromandibular reconstruction using free tissue transfer can delay additional therapies directed at cancer treatment and prevent patients from returning to normal oral function. Understanding and strict adherence to principles of rigid fixation is critical in preventing complications. Early surgical intervention for hardware exposure as well as utilization of locoregional flaps may prevent the need for more ex tensive revision surgery. [...] Thieme Medical Publishers, Inc. 333 Seventh Avenue, 18th Floor, New York, NY 10001, USA Article in Thieme eJournals: Table of contents  |  Abstract  |  Full text View on Web

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Weekly Symptom Profiles of Non‐hospitalized Individuals Infected with SARS‐CoV‐2 During the Omicron Outbreak in Hong Kong: A Retrospective Observational Study from a Telemedicine Centre

alexandrossfakianakis shared this article with you from Inoreader Weekly Symptom Profiles of Non‐hospitalized Individuals Infected with SARS‐CoV‐2 During the Omicron Outbreak in Hong Kong: A Retrospective Observational Study from a Telemedicine Centre via Journal of Medical Virology Abstract Background Omicron BA.2.2 is the dominant variant in Hong Kong outbreak since December-31 2021. There is no study reporting the weekly symptom profile after infection. Methods In this retrospective study, participants who tested positive for SARS-CoV-2 after December-31 2021 and registered in the telemedicine system between March 14-May 6 2022 were analysed. Findings Among registered 12950 self-quarantined COVID-19 positive patients, 11776 symptomatic patients were included for weekly symptom profile analysis. 4718 (40.1%) patients reported symptoms in the first week after positive test, 2501 (21.2%) in the second week, 1498 (12.7%) in the third week, 1048 (8.9%) in the fourth week, and 2011 (17.1%) in over four weeks. Cough was the most common symptom in all participants. Patients in the first week had higher odds of reporting fever (0.206, 95% CI 0.161-0.263, p<0.001) and sore throat (0.228, 95% CI 0.208-0.252, p<0.001). Patients in over 4 weeks had a higher odds of reporting fatigue (1.263, 95% CI 1.139-1.402, p<0.001). Further, having at least two vaccine doses linked to lower odds of having fever (0.675, 95% CI 0.562-0.811, p<0.001), but not associated with the presence of cough and fatigue. Diabetic patients had higher odds of reporting diarrhea (1.637, 95% CI 1.351-1.982, p<0.001). Conclusion Symptoms from omicron infection may last for more than four weeks and symptom profiles vary from week to week. Vaccination and comorbidity affect the symptom profiles. This article is protected by copyright. All rights reserved. View on Web

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H‐Type Tracheoesophageal Fistula Cannulation for Rapid Intraoperative Localization

alexandrossfakianakis shared this article with you from Inoreader H‐Type Tracheoesophageal Fistula Cannulation for Rapid Intraoperative Localization via The Laryngoscope Various techniques for tracheoesophageal fistula cannulation have been reported. In this case, we created a loop using a plastic catheter. The loop allowed us to create traction for rapid intraoperative localization and to pull a difficult-to-reach fistula, superiorly into the neck, to be reached through a cervical approach. Laryngoscope, 2022 View on Web

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Clinical evaluation and patient related outcomes of one‐ and two‐piece zirconia implants at five years of loading: A case series study

alexandrossfakianakis shared this article with you from Inoreader Clinical evaluation and patient related outcomes of one‐ and two‐piece zirconia implants at five years of loading: A case series study via Journal of Esthetic and Restorative Dentistry Abstract Objective The objective of this study was to investigate the survival and biological and mechanical complications of one-piece and two-piece zirconia implants at five years of loading. Materials and Methods Consecutive patients receiving zirconia implants were studied, collecting data at five years of loading on their clinical history, peri-implant health status, mechanical complications, esthetic results, and patient related outcomes. Results The study included 18 patients with 29 implants. The survival rate was 86% in implant-based analysis and 78% in patient-based analysis. There were no cases of peri-implantitis, but mucositis was present in 53% of implants. A mean of 4.1 ± 0.81 mm was obtained for probing depth and 1.6 ± 0.9 mm for crestal bone loss (radiographic assessment). There were no implant fractures. Major (10%) and minor (10%) prosthesis complications were observed. The esthetic outcome was moderate to almost perfect, with a high level of patient satisfaction. No significant association was found between survival rate and the presence of mucositis around one- or two-piece implants or any other study variable. Conclusions The survival rate is low for one- and two-piece zirconia implants. Both types of implants demonstrated a low mechanical complication rate. The incidence of periimplantitis is low but mucositis is present in 50%. Patient satisfaction related to esthetics and function is moderate to high. They represent a good option for patients requiring an alternative to titanium implants. Clinical Relevance Zirconia implants appear to be an alternative to the titanium option and may be indicated for patients requiring "metal-free" restorations. View on Web

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Three‐point sectional‐cast digital method for transferring the interocclusal relationship for full‐mouth rehabilitation of worn dentition

alexandrossfakianakis shared this article with you from Inoreader Three‐point sectional‐cast digital method for transferring the interocclusal relationship for full‐mouth rehabilitation of worn dentition via Journal of Prosthodontics Abstract For full-mouth rehabilitation of worn dentition, "diagnostic" interim restorations are required to reestablish the interocclusal relationship. It is important but challenging to transfer the interocclusal relationship, and to map the basic form and contour of interim restorations to the final restorations. Alignment of interim restorations and working casts is difficult when using digital workflows because of a lack of consistent hard tissue reference points. The digital workflow presented in this study used a "3-point sectional-cast digital cross-mounting method" to transfer the interocclusal relationship during full-mouth rehabilitation. An intermediate cast was made with 3 interim restorations: 1 on an incisor and 2 on molars. The interocclusal relationship and occlusal morphologies of the diagnostic interim prostheses were transferred and aligned to working casts using the 3-point sectional casts. This article is protected by copyright. All rights reserved View on Web

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