Reduced Hospitalizations, Emergency Room Visits, and Costs Associated with a Web-Based Health Literacy, Aligned-Incentive Intervention: Mixed Methods Study*Journal* of *Medical Internet Research*Thu Oct 17, 2019 17:45A Comparison of Users and Nonusers of a Web-Based Intervention for Carers of Older Persons With Alzheimer Disease and Related Dementias: Mixed Methods Secondary Analysis*Journal* of *Medical Internet Research*Thu Oct 17, 2019 17:45Psychosocial Factors Affecting Artificial Intelligence...
10:38
Study of abdominal wall muscle innervation applied to large‐defect closure in congenital diaphragmatic herniaINTRODUCTION In large congenital diaphragmatic hernias (CDHs), direct suture of the diaphragm is impossible. Surgeons can use a triangular internal oblique muscle (IOM) plus transverse abdominis muscle (TAM) flap. Its caudal limit faces the medial extremity of the 11th rib. Clinical studies show that the flap is not hypotonic but that the procedure could expose patients already presenting...
10:36
Frequent appearance of club cell (Clara cell)‐like cells as a histological marker for ALK‐positive lung adenocarcinomaAnaplastic lymphoma kinase‐rearranged (ALK +) lung cancers show characteristic histological features, such as solid signet ring cell patterns and mucinous cribriform patterns; however, these features are not always observed in ALK + lung cancers. We noticed that club cell (Clara cell)‐like cells (CLCs) were frequently present in the papillary portion of ALK + lung adenocarcinomas....
10:33
Acute Effects of Foam Rolling on Range of Motion in Healthy Adults: A Systematic Review with Multilevel Meta-analysisAbstract Background Foam rolling (FR) has been demonstrated to acutely enhance joint range of motion (ROM). However, data syntheses pooling the effect sizes across studies are scarce. It is, furthermore, unknown which moderators affect the treatment outcome. Objective To quantify the immediate effects of FR on ROM in healthy adults. ...Latest Results for Sports Medicine03:00The Effects...
10:29
Assessing the accuracy of two posterior tooth-size discrepancy prediction methods based on virtual occlusal setups: The Angle Orthodontist, Ahead of Print.
10:28
Frankel 2 appliance versus the Modified Twin Block appliance for Phase 1 treatment of Class II division 1 malocclusion in children and adolescents: A randomized clinical trial: The Angle Orthodontist, Ahead of Print.
10:28
More about Factor H Autoantibodies in Membranous Nephropathy: To the Editor: Primary membranous nephropathy, one of the most common causes of nephrotic syndrome in adults, results from the deposition of IgG and complement components in the subepithelial layer of the glomerular basement membrane. In 70 to 80% of patients with this condition, antibodies that…
10:28
Health sciences : nature.com , MiR-129-5p inhibits liver cancer growth by targeting calcium calmodulin-dependent protein kinase IV (CAMK4)18hYour microbiome is what you eat18hBuilding community in the gut: a role for mucosal serotonin18hCD9 blockade suppresses disease progression of high-risk pediatric B-cell precursor acute lymphoblastic leukemia and enhances chemosensitivity18hCirc-Spidr enhances axon regeneration after peripheral nerve injury18hEffects of stroke beyond the brain18hNeurocognitive...
10:17
JAMA Otolaryngology–Head & Neck Surgery Online First , Care Value for Older Patients Receiving Radiotherapy With or Without Cisplatin or Cetuximab for Head/Neck CancerThis cohort study uses the SEER-Medicare outcomes and claims database to evaluate the quality, outcomes, and costs associated with radiation therapy with or without cisplatin or cetuximab for older adults with stage III to IVB head and neck cancer.14hHarms of Pediatric Thyroid Cancer OverdiagnosisTo the Editor We read with interest...
10:16
Pesticide Action NetworkA pesticide-free traditionPAN board member Kyle Powys Whyte holds the Timnick Chair in the Humanities at Michigan State University. He is Associate Professor of Philosophy and Community Sustainability and a member of the Potawatomi Nation. Here, Kyle shares thoughts and reflections around wild rice harvesting, a practice that exemplifies Indigenous peoples' leadership on food & farming in the U.S. I saw a fellow Anishinaabe friend recently and asked after their work. Knowing...
10:13
Calcification of the fibular free flap pedicle, an unusual cause of neck and throat pain: A 58-year-old man presented with painful swallowing and pain in his left submental area that hurt when turning his neck to the left, and was more noticeable during daily cycling. He had become aware of a bony lump in the area over the course of six months.
10:10
Accuracy of a new custom-made bone-supported osteotomy and repositioning guide system for reconstruction of the mandibular ramus using costochondral grafts: a preliminary study: Mandibular reconstruction in patients with hemifacial microsomia is still challenging. In this study we have introduced a costochondral graft (CCG) for reconstruction of the mandibular ramus, and reported a bone-supported osteotomy and repositioning guide system for transfer of a virtual plan. Fourteen young children with...
10:10
Identification of MYO6 copy number variation associated with cochlear aplasia by targeted sequencing
Identification of MYO6 copy number variation associated with cochlear aplasia by targeted sequencing: Publication date: Available online 16 October 2019Source: International Journal of Pediatric OtorhinolaryngologyAuthor(s): Sun Lianhua, Wang Xiaowen, Hou Shule, Liang Min, Yang JunAbstractCopy number variation is an extensively studied cause of hereditary diseases. However, its role in hereditary sensorineural deafness has been rarely reported. Using targeted sequencing, SNP array and qPCR, we found...
10:09
Closure of radial forearm free flap donor site: A comparative study between keystone flap and skin graft: AbstractBackgroundThe aim was to investigate the feasibility of radial forearm free flap (RFFF) donor site closure by keystone flap (KF) and compare its outcomes to those of skin graft (SG) closure.MethodsOne hundred and one patients who underwent RFFF for head and neck reconstruction were included (35 KF closure and 65 SG closure). Duration of wound healing and donor site complications was collected....
10:09
Risk factors for auricular hematoma and recurrence after drainage: Objectives/HypothesisTo review an institutional experience with auricular hematoma across all clinical settings including the emergency department (ED) and outpatient clinics at an urban tertiary care academic hospital, characterize practice patterns across setting and specialty, and assess for factors predictive of treatment success.MethodsPatients presenting to the ED, admitted to an inpatient ward, or seen in the outpatient setting...
10:09
Prospective evaluation of oral premalignant lesions using a multimodal imaging system: a pilot study
Prospective evaluation of oral premalignant lesions using a multimodal imaging system: a pilot study: AbstractBackgroundMultimodal optical imaging, incorporating reflectance and fluorescence modalities, is a promising tool to detect oral premalignant lesions in real‐time.MethodsImages were acquired from 171 sites in 66 patient visits for clinical evaluation of oral lesions. An automated algorithm was used to classify lesions as high‐ or low‐risk for neoplasia. Biopsies were acquired at clinically...
10:08
Complement C3a induces axonal hypomyelination in the periventricular white matter through activation of WNT/β‐catenin signal pathway in septic neonatal rats experimentally induced by lipopolysaccharide: AbstractNeuroinflammation is thought to play a pivotal role in the pathogenesis of periventricular white matter (PWM) damage (PWMD) induced by neonatal sepsis. Because the complement cascade is implicated in inflammatory response, this study was carried out to determine whether C3a is involved in...
10:08
Shields for Emotional Well-Being in Chinese Adolescents Who Switch Schools: The Role of Teacher Autonomy Support and GritAlthough prior research has demonstrated that switching schools poses a risk for academic and behavioral functioning among adolescents, relatively little is known about their emotional adjustment, or how it affects emotional well-being. Moreover, the cumulative effects of multiple risk and protective factors on their emotional well-being are even less covered in the existing literature....
10:06
Use and Cost of a Hypoglossal Nerve Stimulator Device for Obstructive Sleep Apnea: This economic evaluation based on publicly available data assesses the use and cost of an implantable device, approved by the US Food and Drug Administration in 2014, that offers a unique alternative to patients with moderate to severe obstructive sleep apnea and poor response to continuous positive airway pressure.
09:59
Solitary Mucus Cast at the Wharton Duct Orifice: A woman presents with recurring left submandibular gland swelling and pain, and a sialoendoscopy shows a mucus cast, which has extensive eosinophil infiltrate seen on histologic examination. What is your diagnosis?
09:59
Concurrent Internal Jugular Vein Phlebectasia and Omohyoid Sling Syndrome: This case report describes a woman in her 20s who presented with a right lower neck swelling that appeared intermittently, especially during swallowing and coughing.
09:59
Transnasal-Transpterygoid Endoscopic Removal of an 18 F–Choline-Avid Parathyroid Carcinoma in the Skull Base: This case report describes a patient with a medical history of symptomatic primary hyperparathyroidism who was found to have an atypical parathyroid neoplasm at the right skull base with an infiltrating pattern, which was treated by transnasal-transpterygoid endoscopic removal.
09:59
Association of Singing With the Development of Pediatric Voice Disorders: To the Editor Clarós et al should be complimented on the article "Association Between the Development of Pediatric Voice Disorders and Singing in Children's Choir," published online in March. The study was important. However, the authors might consider another explanation for their findings. Their article suggests an association between good vocal health and choir singing based on attention to healthy singing techniques in...
09:58
Factors to Consider When Contemplating Posttreatment Surveillance for Survivors of HPV-Associated Oropharyngeal Squamous Cell Carcinoma: In this issue of JAMA Otolaryngology–Head & Neck Surgery, Masroor at al explore the outcomes associated with adherence to the current National Comprehensive Cancer Network (NCCN) posttreatment surveillance recommendations for patients with human papillomavirus–associated oropharyngeal squamous cell carcinoma (HPV-associated OPSCC). Recognition of the favorable...
09:58
Journal of Clinical PsychologyEmotion regulation in posttraumatic stress disorder (PTSD): Rumination accounts for the association between emotion regulation difficulties and PTSD severityAbstract Objective The current study investigated whether rumination accounts for the relationship between multiple aspects of emotion regulation (ER) difficulties and posttraumatic stress disorder (PTSD) severity. Method Participants were 90 community members (43% diagnosed with PTSD; M age = 26.7, 86% female) who...
09:55
Food Safety News , Coalition called "The Baby Food Council" says it will take on heavy metalsA coalition of companies and others formed last January announced Thursday it was taking on "the challenge of reducing heavy metals in young children's food. With the U.S. Department of Agriculture (USDA) and Food and Drug Administration (FDA) as "technical advisors to the effort," The Baby Food Council, organized in January by Cornell University and the Environmental Defense Fund, includes infant and toddler...
09:54
Psychology & Marketing Antecedents and outcomes of digital influencer endorsement: An exploratory...
Psychology & MarketingAntecedents and outcomes of digital influencer endorsement: An exploratory studyAbstract The advertising and marketing literature have established that celebrity endorsements constitute an effective way to enhance attitudes toward brands and increase purchase intents. However, there are no relevant studies on digital influencers. This study addresses the research gap by examining the effect of digital influencers' attractiveness and the effect of the congruence between a...
09:54
World of PsychologyThe Productive Hobby TrapThat nagging thought was back. What should I be doing? I had a spare few minutes while my son was napping, I should maximize my productivity. Shouldn't I? As a little girl, I watched my mother through the picture window working outside in her legendary flower garden. She was a prolific gardener and painter. There was even an article about her award-winning garden in the newspaper. I don't have a single memory of her putting her feet up and readiWorld of...
09:53
Indian Journal of Medical and Paediatric Oncology : Interstitial lung disease associated with chemotherapy treatment of metastatic adenocarcinoma of colonDevendra PalIndian Journal of Medical and Paediatric Oncology 2019 40(2):298-300Indian Journal of Medical and Paediatric Oncology : 2014 - 35(4)7hIt all begins with a promise!Dhananjay KelkarIndian Journal of Medical and Paediatric Oncology 2019 40(2):279-281Indian Journal of Medical and Paediatric Oncology : 2014 - 35(4)7hTeenage and young adult...
09:52
Radioembolización en tumores hepáticos: Publication date: Available online 16 October 2019Source: Revista Española de Medicina Nuclear e Imagen MolecularAuthor(s): L. Carrion-Martin, J. Orcajo Rincón, A. Rotger, M. Gonzalez-Leyte, L. Márquez Pérez, M. Echenagusia, A. MatillaResumenLa enfermedad hepática tumoral es cada vez más frecuente. Su peculiar forma de irrigación, predominantemente arterial, a diferencia del resto del hígado con flujo fundamentalmente por vía portal, hace a los tumores susceptibles...
09:51
Computer Speech & LanguageEditorial BoardPublication date: January 2020Source: Computer Speech & Language, Volume 59Author(s):Computer Speech & LanguageThu Oct 17, 2019 06:52VoxCeleb: Large-scale Speaker Verification in the WildPublication date: Available online 16 October 2019Source: Computer Speech & LanguageAuthor(s): Arsha Nagrani, Joon Son Chung, Weidi Xie, Andrew ZissermanAbstractThe objective of this work is speaker recognition under noisy and unconstrained conditions. We make...
09:48
American Goiter AssociationThe effect of overweight and obesity on liver biochemical markers in children and adolescents.Related ArticlesThe effect of overweight and obesity on liver biochemical markers in children and adolescents. J Clin Endocrinol Metab. 2019 Oct 16;: Authors: Johansen MJ, Gade J, Stender S, Frithioff-Bøjsøe C, Lund MAV, Chabanova E, Thomsen HS, Pedersen O, Fonvig CE, Hansen T, Holm JC Abstract BACKGROUND: Elevated plasma concentrations of liver enzymes are routinely used as markers...
09:47
Undertriaged trauma patients: Who are we missing?BACKGROUND Trauma team activation (TTA) criteria, set by the American College of Surgeons Committee on Trauma, are used to identify patients prehospital who are at highest risk for severe injury and mobilize the optimal resources. Patients are undertriaged if they are severely injured (Injury Severity Score, ≥16) but do not meet TTA criteria. This study examined the epidemiology and injury patterns of undertriaged patients and potential clinical effects....
10:28
The Application of Xpert Mycobacterium tuberculosis/Rifampicin, Quantitative Polymerase Chain Reaction and High Resolution Melting Curve in the Diagnosis of Superficial Lymph Node TB.Objective: The diagnostic sensitivity and specificity of conventional methods for superficial lymph node tuberculosis (LNTB) are not ideal. We evaluated several novel methods including Xpert Mycobacterium tuberculosis/rifampicin (Xpert MTB/RIF) technology, quantitative fluorescence Polymerase Chain Reaction (qPCR) and...
10:27
An unusual presentation of gastric mucosa-associated lymphoid tissue (MALT) lymphoma following blunt abdominal traumaA 79-year-old woman presented to the emergency department following a motor vehicle collision. As part of her workup she underwent a CT scan which identified a large mass containing calcifications centred around the gastric antrum, and while being assessed she produced 500 mL of haematemesis. An endoscopy revealed an area of friable mucosa the nature of which was uncertain, and multiple...
10:26
Pneumomediastinum and subcutaneous emphysema: complication of cocaine usePneumomediastinum is more frequent in young men and usually presents in association with subcutaneous emphysema. It can occur in case of oesophageal or chest trauma, be iatrogenic or develop spontaneously, in case of emesis, coughing or forceful straining. Use of illicit drugs, such as cocaine, has been associated with multiple respiratory complications, including pneumomediastinum and subcutaneous emphysema. The pathogenesis...
10:26
The Journal of Physiology ,Synaptic cleft microenvironment influences potassium permeation and synaptic transmission in hair cells surrounded by calyx afferents in the turtleKey points In central regions of vestibular semicircular canal epithelia, the [K+] c in the synaptic cleft contributes to setting the hair cell and afferent membrane potentials. The potassium efflux from type I hair cells results from the interdependent gating of three conductances. Elevation of [K+] c occurs through a calcium‐activated...
09:46
Nature Communications - current - nature.com science feedsMulti-strategic RNA-seq analysis reveals a high-resolution transcriptional landscape in cottonNature Communications, Published online: 17 October 2019; doi:10.1038/s41467-019-12575-xIn-depth functional characterization of genomes relies on comprehensive transcriptome data. Here, the authors employ four complementary RNA sequencing technologies to explore the transcription landscape across 16 tissues or different organ types in diploid A genome...
09:45
Clinical Oral InvestigationsPeriodontal status of children with primary immunodeficiencies: a systematic reviewAbstract Objective The aim of this systematic review was to appraise the existing literature on periodontal disease in children affected by different types of neutrophil-associated primary immunodeficiencies (PIDs). Methods A PRESS-validated search strategy was developed to search through databases MEDLINClinical Oral InvestigationsThu Oct 17, 2019 17:00Oral & Maxillofacial SurgeryResponse...
09:45
Clinical Otolaryngology Alternate method for designing laryngoplasty implant using actual size CT...
Clinical OtolaryngologyAlternate method for designing laryngoplasty implant using actual size CT scan images on a touchscreen device with a stylusAbstract Since publishing our article, Custom designing laryngoplasty implant using actual size CT scan images on a mobile device,1 we have refined our technique to improve the accuracy and time required for the procedure using smart phones with a stylus that allows direct sketching on the screen. The published technique starts with taking a screenshot...
09:44
Annals of NeurologyAntiepileptic drugs and suicide: the role of prior suicidal behavior and parental psychiatric disorderAbstract Objective To examine if prior suicidal behavior and familial predisposition to psychiatric disorders modify the association between antiepileptic drug use and completed suicide. Methods Using the Danish National Prescription Register, we identified all incident users of antiepileptic drugs aged 15 years or older in Denmark between July 1997 and December 2015. We carried...
09:43
NEJM : ResearchRandomized Trial of Medical versus Surgical Treatment for Refractory HeartburnIn the United States, approximately 20% of adults regularly have symptoms of gastroesophageal reflux disease (GERD), and annual costs for managing GERD exceed $12 billion. Patients with heartburn, the cardinal symptom of GERD, report reduced work productivity and significant impairments in…NEJM : ResearchWed Oct 16, 2019 17:0020-Year Follow-up of Statins in Children with Familial HypercholesterolemiaFamilial...
09:42
Seminars in plastic surgeryBreast Implants and RadiationSeminars in Plastic Surgery 2019; 33: 240-246DOI: 10.1055/s-0039-1696963One of the most influential factors in the success of breast reconstruction is whether or not radiation therapy has or will be performed. While traditional teaching is that all breasts treated with radiation therapy must be reconstructed with an autologous component, many reconstructive surgeons perform implant-based breast reconstruction without an autologous component...
09:42
Abdominal RadiologyNodal drainage pathways in primary rectal cancer: anatomy of regional and distant nodal spreadAbstract Nodal involvement is a significant prognostic factor in rectal cancer and difficult to assess preoperatively. An understanding of the patterns of nodal spread from different regions of the rectum can assist in this process and is essential for the purposes of surgical planning. In this article we define patterns of spread to mesenteric and pelvic sidewall nodal subgroups and discuss...
09:40
Annals of Intensive Care - Latest ArticlesImpact of natural light exposure on delirium burden in adult patients receiving invasive mechanical ventilation in the ICU: a prospective studyTo determine whether potential exposure to natural light via windows is associated with reduced delirium burden in critically ill patients admitted to the ICU in a single room.Annals of Intensive Care - Latest ArticlesWed Oct 16, 2019 17:00Growth differentiation factor 15 and early prognosis after out-of-hospital cardiac...
09:39
Allergologia et ImmunopathologiaThe relationship between second-hand smoke and wheezing in infants from Córdoba, ArgentinaPublication date: Available online 16 October 2019Source: Allergologia et ImmunopathologiaAuthor(s): A. Teijeiro, M.N. Cuello, M.G. Raiden, R.E. Vieyra, D. Solé, P. Ellwood, R.M. GomezAbstractBackgroundWheezing constitutes a common respiratory symptom in children, and several risk factors have been associated with the prevalence of recurrent wheezing (RW) and its severity, especially...
09:38
Journal of Biophotonics ,Reliability of wavefront shaping based on coherent optical adaptive technique in deep tissue focusingWavefront shaping can compensate the wavefront distortions in deep tissue focusing, leading to an improved penetration depth. However, when using the backscattered signals as the feedback, unexpected compensation bias may be introduced, resulting in focusing position deviations or even no focus in the illumination focal plane. Here we investigated the reliability of wavefront...
09:37
Journal of Human Evolution , First record of a fossil monkey (Primates, Cercopithecidae) from the Late Pliocene of SerbiaPublication date: December 2019Source: Journal of Human Evolution, Volume 137Author(s): Predrag Radović, Joshua Lindal, Zoran Marković, Sanja Alaburić, Mirjana RoksandicAbstractThe cercopithecid fossil record of the Balkan Peninsula extends from the Late Miocene to the Early Pleistocene, but to date no fossils of non-human primates have been identified in Serbia. Here we report...
09:36
Academic Radiology ,Burnout Phenomenon and Its Predictors in Radiology ResidentsPublication date: Available online 16 October 2019Source: Academic RadiologyAuthor(s): Abdulmajeed Bin Dahmash, Fawziah Khalid Alorfi, Abdulaziz Alharbi, Abdulrahman Aldayel, Ahmed M. Kamel, Mohammed AlmoaiqelRationale and ObjectivesThe purpose of this study is to evaluate the prevalence of burnout and its associated risk factors in radiology residents in Saudi Arabia.Materials and MethodsThis cross-sectional study was...
09:35
Antimicrobial Resistance and Infection Control - Sources and reservoirs of Staphylococcus capitis...
Antimicrobial Resistance and Infection Control - Sources and reservoirs of Staphylococcus capitis NRCS-A inside a NICUThe methicillin-resistant clone Staphylococcus capitis NRCS-A, involved in sepsis in neonatal intensive care units (NICUs) worldwide, is able to persist and spread in NICUs, suggesting the presence of reservoirs ...Antimicrobial Resistance and Infection Control - Latest ArticlesWed Oct 16, 2019 17:00Molecular and phenotypic characterization of clinical isolates belonging to a KPC-2-producing...
09:35
American Journal of Medical Genetics Part A ,Brain white matter abnormalities associated with copy number variantsAbstract White matter (WM) signal abnormalities are demonstrated in various neurodevelopmental disorders on brain magnetic resonance imaging (MRI). The pattern of WM abnormalities can aid in the diagnostic process. This study aims to characterize the WM changes found in microdeletion/microduplication syndromes. Thirteen patients with neurodevelopmental disorders due to copy number variations...
09:34
Macrophage activation syndrome, a rare complication of primary Sjögren's syndrome: a case report ,.B. S. Kane, M. Niasse, A. Faye, N. D. Diack, B. Djiba, M. Dieng, M. Sow, A. C. Ndao, N. Diagne, S. Ndongo & A. Pouye Journal of Medical Case Reports volume 13, Article number: 309 (2019) | Download CitationArticle metrics1 AltmetricMetricsdetailsAbstractBackgroundThe association of macrophage activation syndrome and primary Sjögren's syndrome has been rarely reported in the literature. We report...
09:33
Clinical Cases , Case 32-2019: A 70-Year-Old Woman with Rapidly Progressive AtaxiaPresentation of Case. Dr. Kun-Wei Song (Neurology): A 70-year-old woman was admitted to this hospital because of rapidly progressive ataxia. The patient had been in her usual state of good health until 3 months before this admission, when fatigue and general unsteadiness developed. Two months…Clinical CasesWed Oct 16, 2019 17:00Journal of Medical Case Reports - Latest ArticlesSclerosing peritonitis presenting as complete...
09:32
Long non-coding RNA HCP5 serves as a ceRNA sponging miR-17-5p and miR-27a/b to regulate the pathogenesis of childhood obesity via the MAPK signaling pathway: Journal Name: Journal of Pediatric Endocrinology and MetabolismIssue: Ahead of print
09:32
NTCP model for postoperative complications and one-year mortality after trimodality treatment in oesophageal cancer: Radical resection has long been the mainstay of treatment in patients with locoregionally advanced oesophageal cancer. However, outcome with this single modality treatment was poor with five-year survival rates ranging between 14% and 35% [1]. In a quest to improve outcome, several neoadjuvant and adjuvant strategies using chemotherapy or chemoradiotherapy have been investigated [2,3]....
09:31
CD200 Checkpoint Reversal:A Novel Approach to Immunotherapy: Purpose: Advances in immunotherapy have revolutionized care for some cancer patients. However, current checkpoint inhibitors are associated with significant toxicity and yield poor responses for patients with central nervous system tumors, calling into question whether cancer immunotherapy can be applied to glioblastoma multiforme. We determined that targeting the CD200 activation receptors (CD200AR) of the CD200 checkpoint with a peptide...
09:30
A somatostatin receptor subtype-3 (SST3) peptide agonist shows antitumor effects in experimental models of Nonfunctioning Pituitary Tumors: Purpose: Somatostatin-analogs (SSAs) are efficacious and safe treatments for a variety of neuroendocrine tumors, especially pituitary neuroendocrine tumors (PitNETs). Their therapeutic effects are mainly mediated by somatostatin receptors SST2 and SST5. Most SSAs, such as Octreotide/Lanreotide/Pasireotide, are either nonselective or activate mainly SST2. However,...
09:30
Radiotherapy can increase the risk of ischemic cerebrovascular disease in head and neck cancer patients: A Korean population-based cohort study: For HNC patients, RT is an essential curative and organ-preserving treatment modality, which can be delivered by itself or combined with chemotherapy or surgery. However, several reports have demonstrated that RT is related to an increased risk of CVD in HNC patients [1–3]. It might have resulted from the chronic side effects of RT on the large to medium...
09:30
CancerCorrection: Intratumoural-infiltrating CD4 + and FOXP3 + T cells as strong positive predictive markers for the prognosis of resectable colorectal cancerBritish Journal of Cancer, Published online: 17 October 2019; doi:10.1038/s41416-019-0605-4Correction: Intratumoural-infiltrating CD4 + and FOXP3 + T cells as strong positive predictive markers for the prognosis of resectable colorectal cancerCancerWed Oct 16, 2019 17:00Cancer Biotherapy & Radiopharmaceuticals - Table of ContentsLncRNA WT1-AS...
09:29
Chip to Evaluate Health of Immune System from Blood Sample: Knowing how well a patient's immune system is functioning may be very useful in diagnosing a disease and guiding the course of therapy. Researchers from Nanyang Technological University in Singapore are making this a reality, having developed a hybrid chip that assesses the health of white blood cells in a whole blood sample.The microfluidic chip has a series of components that separate white blood cells from all the other components of...
09:28
Chip to Evaluate Health of Immune System from Blood Sample: Knowing how well a patient's immune system is functioning may be very useful in diagnosing a disease and guiding the course of therapy. Researchers from Nanyang Technological University in Singapore are making this a reality, having developed a hybrid chip that assesses the health of white blood cells in a whole blood sample.The microfluidic chip has a series of components that separate white blood cells from all the other components of...
09:28
Soft Auditory Brainstem Hearing Implants from Platinum Kirigami: People who have hearing loss because of inner ear damage or from a poorly functioning auditory nerve are not helped by cochlear and middle ear implants. Auditory brainstem implants (ABI), which bypass most of the hearing system and send signals directly to the auditory brainstem, are the best option for such patients. But currently these devices rely on rigid components that do not fit perfectly with each patient's unique anatomy. This...
09:27
Antiplasmodial Activity Assay of 3-Chloro-4-(4-chlorophenoxy) Aniline Combinations with Artesunate or Chloroquine In Vitro and in a Mouse ModelMalaria is the eighth highest contributor to global disease burden with 212 million cases and 429,000 deaths reported in 2015. There is an urgent need to develop multiple target drug to curb growing resistance by Plasmodia due to use of single target drugs and lack of vaccines. Based on a previous study, 3-chloro-4-(4-chlorophenoxy) aniline (ANI) inhibits...
09:27
[ASAP] Encapsulating a Single Nanoprobe in a Multifunctional Nanogel for High-Fidelity Imaging of Caspase Activity in VivoAnalytical ChemistryDOI: 10.1021/acs.analchem.9b02834Analytical ChemistryWed Oct 16, 2019 21:00[ASAP] Quantifying Ligand–Protein Binding Kinetics with Self-Assembled Nano-oscillatorsAnalytical ChemistryDOI: 10.1021/acs.analchem.9b04195Analytical ChemistryWed Oct 16, 2019 21:00[ASAP] Extending the Limit of Measurement for Dual H and O Isotope Ratios Using ThermolysisAnalytical...
09:27
Journal of Anatomy , Human biological variation in sesamoid bone prevalence: the curious case of the fabellaThe fabella, a sesamoid bone in the knee, is ~3.5× more common today than 100 years ago. We performed meta‐analyses on prevalence rate studies from 1875–2019, and found (i) fabellae are more common in men, older individuals, and Asian/Oceania populations than women, younger individuals, and North American/African populations (ii) 72.94% of cases are bilateral, and (iii) among unilateral cases,...
09:24
AllergyPulmonary IL‐33 orchestrates innate immune cells to mediate RSV‐evoked airway hyperreactivity and eosinophiliaAbstract Background Respiratory syncytial virus (RSV) infection is epidemiologically linked to asthma. During RSV infection, IL‐33 is elevated and promotes immune cell activation, leading to the development of asthma. However, which immune cells are responsible for triggering airway hyperreactivity (AHR), inflammation and eosinophilia remained to be clarified. We aimed to elucidate...
09:23
Study of lymph node vascular relationships of the inferior epigastric veins: The solve anatomical...
Study of lymph node vascular relationships of the inferior epigastric veins: The solve anatomical studyPublication date: Available online 16 October 2019Source: Journal of Plastic, Reconstructive & Aesthetic SurgeryAuthor(s): C. de Courcey, C. Macdonald, J.T. Hardwicke, J. SkillmanSummaryIntroductionTissue surrounding the superficial inferior epigastric vein (SIEV) can be harvested for vascularised lymph node transfer (vLNT) for treatment of lymphoedema. The aim of this study is to define the...
09:22
Robust structure measures of metabolic networks that predict prokaryotic optimal growth temperature.Related ArticlesRobust structure measures of metabolic networks that predict prokaryotic optimal growth temperature. BMC Bioinformatics. 2019 Oct 15;20(1):499 Authors: Weber Zendrera A, Sokolovska N, Soula HA Abstract BACKGROUND: Metabolic networks reflect the relationships between metabolites (biomolecules) and the enzymes (proteins), and are of particular interest since they describe all chemical...
09:22
Methods and ProtocolsMPs, Vol. 2, Pages 82: Assessing Pancreas Transplant Candidate Cardiac Disease: Preoperative Protocol Development at a Rapidly Growing Transplant ProgramMPs, Vol. 2, Pages 82: Assessing Pancreas Transplant Candidate Cardiac Disease: Preoperative Protocol Development at a Rapidly Growing Transplant Program Methods and Protocols doi: 10.3390/mps2040082 Authors: David St. Michel Tracy Donnelly Towanda Jackson Bradley Taylor Rolf N. Barth Jonathan S. Bromberg Joseph R. Scalea Pancreas...
09:20
Antioxidants, Vol. 8, Pages 491: Effect οf Genotype and Growing Year on the Nutritional, Phytochemical, and Antioxidant Properties of Industrial Hemp (Cannabis sativa L.) SeedsAntioxidants, Vol. 8, Pages 491: Effect οf Genotype and Growing Year on the Nutritional, Phytochemical, and Antioxidant Properties of Industrial Hemp (Cannabis sativa L.) Seeds Antioxidants doi: 10.3390/antiox8100491 Authors: Maria Irakli Eleni Tsaliki Apostolos Kalivas Fotios Kleisiaris Eirini Sarrou Catherine M Cook Cannabis...
09:20
Medicine by Alexandros G. Sfakianakis , Homocysteine is an independent predictor of long-term cardiac mortality in patients with stable coronary...Homocysteine is an independent predictor of long-term cardiac mortality in patients with stable coronary artery disease in the era of statinsBackground Homocysteine (Hcy) is considered a risk factor for cardiovascular disease. Objective To explore the long-term prognostic value of Hcy in patients with stable coronary artery disease (CAD) in the era of...
09:14
