Food security impacts of industrial crop production in sub-Saharan Africa: a systematic review of the impact mechanismsAbstractA number of industrial crops have been promoted in sub-Saharan Africa (SSA) to meet a range of policy objectives including economic growth, rural development, agricultural modernization and energy security. The food security impacts of industrial crop production have received extensive policyattention and have been widely discussed in the academic literature. There is, however,...
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Quantitative 3-dimensional Geometry of the Aging EyelidsBackground: Although facial aging is a well-known phenomenon, it has not been comprehensively characterized in 3 dimensions. This study introduces a novel technique for capturing periorbital structures across age groups using 3-dimensional (3D) imaging and point cloud data collection. Methods: Forty-six white women were divided into 3 age groups: 20–39 years, 40–59 years, and 60+ years. Patients were scanned with the Canfield 3D photogrammetry...
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JNA Is Looking Forward to 2020 and BeyondNo abstract availableThe Promise and Perils of Big Data in the Clinical NeurosciencesNo abstract availablePower and Challenges of Big Data: Why Clinical Researchers Should Not Be IgnoredNo abstract availableRevisiting Ischemia After Brain Injury: Oxygen May Not Be the Only ProblemNo abstract availableAnesthesia and Cognitive Outcome in Elderly Patients: A Narrative ViewpointBetter ways to manage preoperative, intraoperative and postoperative care of surgical...
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Effectiveness of acupuncture for the treatment of postoperative pain: A protocol for a systematic review of randomized controlled trialBackground: This aim of this study is to assess the effectiveness and safety of acupuncture for the treatment of patients with postoperative pain (PPP). Methods: We will carry out a systematic review of the published literature and will comprehensively search Cochrane Library, MEDLINE, EMBASE, CINAHL, PsycINFO, Allied and Complementary Medicine Database, Chinese Biomedical...
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Is Systemic Inflammatory Response Syndrome Relevant to Pulmonary Complications and Mortality in Multiply Injured Children?Background: Systemic inflammatory response syndrome (SIRS) is a well-recognized phenomenon in adult trauma populations. The "initial hit" of the traumatic event is often coupled with a systemic immune response characterized by changes in vital signs and laboratory indicators. A "second hit" from surgery during this time frame often results in acute lung injury, along with deterioration...
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Medical Student Skill Retention After Cardiopulmonary Resuscitation Training: A Cross-Sectional Simulation StudyIntroduction The retention of cardiopulmonary resuscitation skills and the ideal frequency of retraining remain unanswered. This study investigated the retention of cardiopulmonary resuscitation skills by medical students for up to 42 months after training. Methods In a cross-sectional study, 205 medical students received 10 hours of training in basic life support in 3 practical classes,...
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Relationships Between the BRIEF/BRIEF-SR and Performance-Based Neuropsychological Tests in Adolescents with Mild Traumatic Brain InjuryAbstractClinical neuropsychologists typically use both performance-based tests and behavioral rating scales as part of comprehensive assessment. However, literature has suggested that performance-based tests account for limited variance in behavioral rating scales in healthy and clinical populations. Importantly, little work has investigated the relationships between...
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select article Short-term postoperative CPAP may improve the outcomes of velopharyngeal surgery for obstructive sleep apneaResearch articleAbstract onlyShort-term postoperative CPAP may improve the outcomes of velopharyngeal surgery for obstructive sleep apneaGuoping Yin, Mu He, Jinkun Xu, Xin Cao, ... Jingying YeIn Press, Journal Pre-proof, Available online 11 December 2019Purchase PDFArticle previewAbstractAbstractPurposeTo evaluate the effects of short-term postoperative continuous positive airway...
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Prevalence of Asthma among Young Men Residing in Urban Areas with Different Sources of Air Pollution.: Related ArticlesPrevalence of Asthma among Young Men Residing in Urban Areas with Different Sources of Air Pollution.Isr Med Assoc J. 2019 Dec;12(21):785-789Authors: Greenberg N, Carel RS, Dubnov J, Derazne E, Portnov BAAbstract BACKGROUND: Asthma is a common respiratory disease, which is linked to air pollution. However, little is known about the effect of specific air pollution sources...
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Activation of the Protective Arm of the Renin Angiotensin System in Demyelinating Disease: AbstractThe renin angiotensin system (RAS), which is classically known for blood pressure regulation, has functions beyond this. There are two axes of RAS that work to counterbalance each other and are active throughout the body, including the CNS. The pathological axis, consisting of angiotensin II (A1-8), angiotensin converting enzyme (ACE) and the angiotensin II type 1 receptor (AT1R), is upregulated in...
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Isolated Traumatic Brain Injury in the Very Old.: Related ArticlesIsolated Traumatic Brain Injury in the Very Old.Isr Med Assoc J. 2019 Dec;12(21):779-784Authors: Solomon D, Kaminski O, Schrier I, Kashtan H, Stein MAbstract BACKGROUND: Older age is an independent predictor of worse outcome from traumatic brain injury (TBI). No clear guidelines exist for the management of TBI in elderly patients. OBJECTIVES: To describe the outcomes of elderly patients presenting with TBI and intracranial...
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Developing a Comprehensive Geriatric Genogram Assessment Tool.: Related ArticlesDeveloping a Comprehensive Geriatric Genogram Assessment Tool.Isr Med Assoc J. 2019 Dec;12(21):796-800Authors: Samson T, Peleg R, Biderman A, Press YAbstract BACKGROUND: The use of graphic depictions (pictorials) to represent medical conditions is an accepted method that can complement standard methodology of comprehensive geriatric assessment. OBJECTIVES: To use the clinical pathway method to develop...
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The effects of modified constraint-induced movement therapy combined with intensive bimanual training in children with brachial plexus birth injury: a retrospective data base study.: Related ArticlesThe effects of modified constraint-induced movement therapy combined with intensive bimanual training in children with brachial plexus birth injury: a retrospective data base study.Disabil Rehabil. 2019 Dec 08;:1-10Authors: Zielinski IM, van Delft R, Voorman JM, Geurts ACH, Steenbergen B, Aarts PBMAbstract...
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Repeated Intravenous Amantadine Infusions in Advanced Parkinsonism: Experience of a Large Movement Disorder Center.: Related ArticlesRepeated Intravenous Amantadine Infusions in Advanced Parkinsonism: Experience of a Large Movement Disorder Center.Isr Med Assoc J. 2019 Dec;12(21):812-816Authors: Kestenbaum M, Abu Snineh M, Nussbaum T, Gadoth A, Rosenberg A, Hindi A, Zitser J, Thaler A, Giladi N, Gurevich TAbstract BACKGROUND: The effect of repeated intravenous amantadine (IVAM) in advanced...
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Neck pain associated with clinical symptoms in dizzy patients-A cross-sectional study.: Related ArticlesNeck pain associated with clinical symptoms in dizzy patients-A cross-sectional study.Physiother Res Int. 2019 Dec 08;:e1815Authors: Knapstad MK, Nordahl SHG, Skouen JS, Ask T, Goplen FKAbstract OBJECTIVE: Many patients suffer from concurrent neck pain and dizziness. The aim of this study was to describe the clinical symptoms and physical findings in patients with concurrent neck pain...
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Comparison of Neuroborreliosis Between Children and Adults.: Related ArticlesComparison of Neuroborreliosis Between Children and Adults.Pediatr Infect Dis J. 2020 Jan;39(1):7-11Authors: Krawczuk K, Czupryna P, Pancewicz S, Ołdak E, Król M, Moniuszko-Malinowska AAbstract BACKGROUND: Lyme neuroborreliosis (NB) is a tick-borne infectious disorder of the nervous system caused by Borrelia burgdorferi spirochetes. There are not many data available regarding the differences in the course of NB...
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Salivary inflammatory markers in tension type headache and migraine: the SalHead cohort study: AbstractObjectiveTo investigate the possible association between salivary CRP, IL-1β, and IL-6 levels, depression/anxiety and migraine, and tension type headache (TTH) in saliva of these patients.MethodA longitudinal prospective study was conducted on 30 migraineurs, 30 TTH patients, and 30 age-matched healthy controls. Anxiety and depression were measured by using the Hamilton Anxiety Rating Scale (HAM-A),...
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Successful Airway and Anesthesia Management Using a High-Flow Nasal Cannula in a Fibrodysplasia Ossificans Progressiva Patient During General Anesthesia: A Case Report.: Related ArticlesSuccessful Airway and Anesthesia Management Using a High-Flow Nasal Cannula in a Fibrodysplasia Ossificans Progressiva Patient During General Anesthesia: A Case Report.A A Pract. 2019 Dec 04;:Authors: Deguchi Y, Seki H, Tamaki H, Ouchi TAbstract Fibrodysplasia ossificans progressiva (FOP) is a rare hereditary...
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Intestinal adenosquamous carcinoma with a synchronous skin metastasis: a immunohistochemical and molecular analysis: AbstractIntroductionIntestinal adenosquamous carcinoma (ASC) is a rare colorectal neoplasm frequently occurring at onset as a locally advanced disease with distant metastases. The liver is the most common site of metastasis, followed by the peritoneum and the lung. Cutaneous metastases from usual colorectal adenocarcinoma occur in about 3% of cases, both at the time of diagnosis in...
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Autologous Platelet-Rich Plasma in the Treatment of Perianal Fistula in Crohn's Disease: AbstractAimTo assess clinical healing in patients with perianal Crohn's disease with local intrafistular injection of autologous platelet-rich plasma.MethodThe pilot study was conducted at a single centre between January 2013 and December 2015. Autologous platelet-rich plasma was prepared in platelet-rich and platelet-poor fractions for local intrafistular injection in patients with proven, established perianal...
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MT4-MMP promotes invadopodia formation and cell motility in FaDu head and neck cancer cells.: Related ArticlesMT4-MMP promotes invadopodia formation and cell motility in FaDu head and neck cancer cells.Biochem Biophys Res Commun. 2019 Dec 05;:Authors: Yan X, Cao N, Chen Y, Lan HY, Cha JH, Yang WH, Yang MHAbstract Hypoxia-inducible factor-1α (HIF-1α) induces cancer metastasis. We previously demonstrated that HIF-1α-induced membrane-type 4 matrix metalloproteinase (MT4-MMP) is involved in hypoxia-mediated...
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Filanesib for the treatment of multiple myeloma.: Related ArticlesFilanesib for the treatment of multiple myeloma.Expert Opin Investig Drugs. 2019 Dec 09;:Authors: Algarín EM, Hernández-García S, Garayoa M, Ocio EMAbstract Introduction: Kinesin spindle protein (KSP) is indispensable for the proper separation of spindle poles during mitosis. Importantly, this protein is expressed only in cells undergoing cell division and hence represents an appealing target for the treatment of cancer. Many...
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Peri-tumoural CD3+ Inflammation and Neutrophil-to-Lymphocyte Ratio Predict Overall Survival in Patients Affected by Colorectal Liver Metastases Treated with Surgery: AbstractBackgroundSystemic and local inflammation plays an important role in many cancers and colorectal liver metastases (CRLM). While the role of local immune response mediated by CD3+ tumour-infiltrating lymphocytes is well-established, new evidence on systemic inflammation and cancer, such as neutrophil-lymphocyte ratio (NLR), is...
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Evolution of surface morphology of Er:YAG laser-machined human bone: AbstractThe extensive research on the laser machining of the bone has been, so far, restricted to drilling and cutting that is one- and two-dimensional machining, respectively. In addition, the surface morphology of the laser machined region has rarely been explored in detail. In view of this, the current work employed three-dimensional laser machining of human bone and reports the distinct surface morphology produced within a laser...
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Osseous ingrowth in allogeneic bone blocks applied for vertical bone augmentation: a preclinical randomised controlled study: AbstractObjectivesThe aim of the present study was the qualitative and quantitative evaluation of osseous graft consolidation using allogeneic bone blocks for vertical bone augmentation in an animal model.Material and methodsStandardised allogeneic and autologous bone blocks were fixed on the frontal skull of 20 adult female pigs and covered with a resorbable collagen membrane....
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The Case of the Irretrievable Mandibular Condyle: My Experience with Utilization of an Extraoral Vertical Ramus Osteotomy in Managing Severely Medially Displaced or Dislocated Mandibular Condyle Fractures: AbstractMedially displaced condylar head fractures pose a challenge for oral and maxillofacial surgeons. Accessing, retrieving, and reducing a displaced fracture is seemingly impossible at times. Consideration of the risks must also be taken, including significant bleeding during exposure, injury...
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Ontogeny of the facial phenotypic variability in Mexican patients with 22q11.2 deletion syndrome: AbstractBackground22q11.2 deletion syndrome is a medical condition that results from genomic loss at chromosome 22. Affected patients exhibit large variability that ranges from a severe condition to mild symptoms. In addition, the spectrum of clinical features differs among populations and even within family members. The facial features related to this syndrome are not an exception, and although part...
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Disease Progression and Outcomes of Pregnancies in Women With Eosinophilic Esophagitis.: Related ArticlesDisease Progression and Outcomes of Pregnancies in Women With Eosinophilic Esophagitis.Clin Gastroenterol Hepatol. 2019 Dec 05;:Authors: Schreiner P, Meissgeier S, Safroneeva E, Greuter T, Rogler G, Schoepfer A, Simon D, Simon HU, Biedermann L, Straumann AAbstract BACKGROUND & AIMS: Eosinophilic esophagitis (EoE) most often affects young patients of reproductive age, yet little is...
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Lack of Standardization in Commercial Thickeners Used in the Management of Dysphagia.: Related ArticlesLack of Standardization in Commercial Thickeners Used in the Management of Dysphagia.Ann Nutr Metab. 2019 Dec 06;:1-6Authors: Salles Machado A, Lenz D, Dos Santos de Souza R, Muniz Eugênio R, Uggere de Andrade T, Costa Pereira T, Coutinho Endringer DAbstract INTRODUCTION: Oral feeding safety is necessary to provide nutrition, hydration, and eating pleasure for patients with dysphagia. Commercial...
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Children with eosinophilic esophagitis in real life: 10 years' experience with a focus on allergic management.: Related ArticlesChildren with eosinophilic esophagitis in real life: 10 years' experience with a focus on allergic management.Allergol Immunopathol (Madr). 2019 Dec 05;:Authors: Azzano P, Villard Truc F, Collardeau-Frachon S, Lachaux AAbstract INTRODUCTION AND OBJECTIVES: Eosinophilic esophagitis (EoE) is frequently miss-diagnosed or overlooked for several years because of the...
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Deep Neck Infections Are Life Threatening Infections of Dental Origin: a Presentation and Management of Selected Cases.: Related ArticlesDeep Neck Infections Are Life Threatening Infections of Dental Origin: a Presentation and Management of Selected Cases.Isr Med Assoc J. 2019 Dec;12(21):806-811Authors: Pesis M, Bar-Droma E, Ilgiyaev A, Givol NAbstract BACKGROUND: Untreated dental caries or even dental manipulations, such as a tooth extraction, might cause direct spread of an odontogenic...
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The Evaluation of Esophageal Motility Using Infusion Manometry with a Trans-nasal Endoscope: A Preliminary Study.: Related ArticlesThe Evaluation of Esophageal Motility Using Infusion Manometry with a Trans-nasal Endoscope: A Preliminary Study.Intern Med. 2019 Dec 06;:Authors: Hata K, Ito M, Boda T, Kotachi T, Kiso M, Hiyama Y, Kuroki K, Yorita N, Nagasaki N, Abduwaili M, Tanaka S, Chayama KAbstract Background and Aim The Chicago classification using high-resolution manometry (HRM) has been...
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Endoscopic Suturing Results in High Technical and Clinical Success Rates for a Variety of Gastrointestinal Pathologies: AbstractPurposeWe report our institution's experience with endoscopic suturing and hypothesize that it has high technical and clinical success.MethodsThis is a retrospective review of patients who underwent a procedure with the endoscopic suturing system between April 2010 and March 2019. Definitions of technical and clinical success were established for each application.ResultsOverall...
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Chemoradiotherapy with FOLFOX for esophageal squamous cell cancer with synchronous rectal cancer: Four case reports and a literature review.: Related ArticlesChemoradiotherapy with FOLFOX for esophageal squamous cell cancer with synchronous rectal cancer: Four case reports and a literature review.Mol Clin Oncol. 2020 Jan;12(1):23-30Authors: Yoshii T, Hara H, Asayama M, Kumekawa Y, Miyazawa S, Takahashi N, Matsushima T, Shimizu S, Saito YAbstract Chemoradiotherapy (CRT) is a valuable treatment...
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Co-Occurrence of Rarest Type of Dysphagia Lusoria (Type N-1) and Eosinophilic Esophagitis in a Cognitively Disabled Individual.: Related ArticlesCo-Occurrence of Rarest Type of Dysphagia Lusoria (Type N-1) and Eosinophilic Esophagitis in a Cognitively Disabled Individual.Case Rep Med. 2019;2019:2890635Authors: Kumar K, Makker J, Tariq H, Ihimoyan A, Chukwunonso C, Niazi M, Lombino M, Kamal M, Patel HKAbstract Dysphagia is an expressive symptom, described by an individual as "difficulty in...
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Preperitoneal Fat Grafting Inhibits the Formation of Intra-abdominal Adhesions in Mice: AbstractBackgroundAdhesion formation contributes to postoperative complications in abdominal and gynaecological surgery. Thus far, the prevention and treatment strategies have focused on mechanical barriers in solid and liquid form, but these methods are not in routine use. As autologous fat grafting has become popular in treatment of hypertrophic scars because of its immunomodulatory effects, we postulated that...
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Genetic identification and molecular modeling characterization of a novel POU3F4 variant in two Italian deaf brothers.: Related ArticlesGenetic identification and molecular modeling characterization of a novel POU3F4 variant in two Italian deaf brothers.Int J Pediatr Otorhinolaryngol. 2019 Nov 22;129:109790Authors: Giannantonio S, Agolini E, Scorpecci A, Anzivino R, Bellacchio E, Cocciadiferro D, Novelli A, Digilio MC, Marsella PAbstract In this report, we describe a novel, probably pathogenic...
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Incidence of Common Mental Disorders in Teachers: Is There a Relationship with Voice Disorders?: Publication date: Available online 2 December 2019Source: Journal of VoiceAuthor(s): Luise Marques da Rocha, Paulinia Leal do Amaral, Suelen de Lima Bach, Mara Behlau, Luciano Dias de Mattos SouzaSummaryObjectiveThis study aims to evaluate the risk factors associated with the incidence of common mental disorders (CMD) in teachers, particularly the possible relationship with voice disorders.Material and...
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Impact of Pregnancy and Glucocorticoid Treatment on NF-κB and MUC5AC in Mucosa of Rat Larynx: Publication date: Available online 2 December 2019Source: Journal of VoiceAuthor(s): Burak Ulkumen, Burcu Artunc Ulkumen, Muhammet Burak Batir, Halil Gursoy Pala, Seda Vatansever, Sirri CamSUMMARYObjectiveThe aim of this study is to reveal physiological expression and distribution of nuclear factor-kappa B (NF-κB) and MUC 5 subtype AC (MUC5AC) in rat laryngeal mucosa and to find out the effect of pregnancy...
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The microRNA-183/96/182 Cluster is Essential for Stereociliary Bundle Formation and Function of Cochlear Sensory Hair Cells.: Related ArticlesThe microRNA-183/96/182 Cluster is Essential for Stereociliary Bundle Formation and Function of Cochlear Sensory Hair Cells.Sci Rep. 2018 12 21;8(1):18022Authors: Geng R, Furness DN, Muraleedharan CK, Zhang J, Dabdoub A, Lin V, Xu SAbstract The microRNA (miR)-183/96/182 cluster plays important roles in the development and functions of sensory organs,...
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Olfactory ensheathing cells from the nasal mucosa and olfactory bulb have distinct membrane properties.: Related ArticlesOlfactory ensheathing cells from the nasal mucosa and olfactory bulb have distinct membrane properties.J Neurosci Res. 2019 Dec 04;:Authors: Smith KE, Whitcroft K, Law S, Andrews P, Choi D, Jagger DJAbstract Transplantation of olfactory ensheathing cells (OECs) is a potential therapy for the regeneration of damaged neurons. While they maintain tissue homeostasis in the...
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Chronic Electrical Stimulation of the Otolith Organ: Preliminary Results in Humans with Bilateral Vestibulopathy and Sensorineural Hearing Loss: Introduction: Bilateral vestibulopathy is an important cause of imbalance that is misdiagnosed. The clinical management of patients with bilateral vestibular loss remains difficult as there is no clear evidence for an effective treatment. In this paper, we try to analyze the effect of chronic electrical stimulation and adaptation to electrical stimulation...
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The need for improved cognitive, hearing and vision assessments for older people with cognitive impairment: a qualitative study.: Related ArticlesThe need for improved cognitive, hearing and vision assessments for older people with cognitive impairment: a qualitative study.BMC Geriatr. 2019 Dec 03;19(1):328Authors: Wolski L, Leroi I, Regan J, Dawes P, Charalambous AP, Thodi C, Prokopiou J, Villeneuve R, Helmer C, Yohannes AM, Himmelsbach IAbstract BACKGROUND: Hearing and vision (sensory)...
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Lateralization of the Vocal Fold: Results of an Exclusive Transoral Approach: Publication date: Available online 5 December 2019Source: Journal of VoiceAuthor(s): Christol Fabre, Nathalie Henrich Bernardoni, Marie-Pierre Aboussouan, Paul F. Castellanos, Ihab AtallahSummaryObjectiveVocal fold paralysis in adduction can result in dyspnea. The authors have previously described an original vocal fold lateralization technique performed exclusively through an endoscopic approach. In this work, we studied...
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Acoustic Psychometric Severity Index of Dysphonia (APSID): Development and Clinical Application: Publication date: Available online 4 December 2019Source: Journal of VoiceAuthor(s): Seung Jin Lee, Hong-Shik Choi, HyangHee KimSummaryObjectives/HypothesisThe purpose of this study was to explore the predictability of the Korean version of the Voice Activity and Participation Profile (K-VAPP) scores and acoustic measures for perceived severity of voice disorders. Furthermore, usefulness of the index...
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Further Evidence for the Implication of the MET Gene in Non-Syndromic Autosomal Recessive Deafness.: Related ArticlesFurther Evidence for the Implication of the MET Gene in Non-Syndromic Autosomal Recessive Deafness.Hum Hered. 2019 Dec 04;:1-8Authors: Bousfiha A, Riahi Z, Elkhattabi L, Bakhchane A, Charoute H, Snoussi K, Bonnet C, Petit C, Barakat AAbstract Mutations in the mesenchymal epithelial transition factor (MET) gene are frequently associated with multiple human cancers but can also...
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A Case of Nervus Laryngeus Superior Paresis Treated With Novafon Local Vibration Voice Therapy: Publication date: Available online 7 December 2019Source: Journal of VoiceAuthor(s): Ben Barsties v. Latoszek, Christopher R. WattsSummaryObjectiveThe aim of the study is to present a case of chronic idiopathic superior laryngeal nerve paresis (SLNp) treated with a novel voice therapy approach called Novafon Local Vibration Voice Therapy (NLVVT).MethodsOutcome measurements including acoustics, aerodynamics,...
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Urinary biomarkers of polycyclic aromatic hydrocarbons and the association with hearing threshold shifts in the United States adults.: Related ArticlesUrinary biomarkers of polycyclic aromatic hydrocarbons and the association with hearing threshold shifts in the United States adults.Environ Sci Pollut Res Int. 2019 Dec 05;:Authors: Chou CW, Chen YY, Wang CC, Kao TW, Wu CJ, Chen YJ, Zhou YC, Chen WLAbstract Polycyclic aromatic hydrocarbons (PAHs) are regarded as environmental pollutants that...
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Associations between tinnitus and glaucoma suggest a common mechanism: A clinical and population-based study: Publication date: Available online 6 December 2019Source: Hearing ResearchAuthor(s): Allison R. Loiselle, Anna Neustaeter, Emile de Kleine, Pim van Dijk, Nomdo M. JansoniusAbstractThe purpose of this study was to determine if there is an association between tinnitus and glaucoma. We tested this by first completing a clinic-based cross-sectional questionnaire study in which we sent a series...
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Rare and unusual case of familial focal dermal hypoplasia (Goltz syndrome) presenting to otolaryngology in the UK.: Related ArticlesRare and unusual case of familial focal dermal hypoplasia (Goltz syndrome) presenting to otolaryngology in the UK.BMJ Case Rep. 2019 Dec 05;12(12):Authors: Freethy A, Acharya V, Iacovidou A, Taghi AAbstract Goltz syndrome or focal dermal hypoplasia (FDH), is an X-linked dominant condition which predominantly involves the skin, limbs and eyes. In otolaryngology,...
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Reprogramming the Inner Ear Can Regrow Hair Cells and Restore Hearing: The combined activation of two molecular signals, Myc and Notch1, can trigger regeneration of hair cell-like cells in adults and facilitate hearing recovery, according to a new study (Nat Commun. 10, 5530 [2019]). In lower vertebrates like birds and fish that suffered hearing loss, the remaining cells divide and regrow new hair cells, restoring hearing and vestibular function. Researchers from Massachusetts Eye and Ear sought...
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Associations of Vestibular Tests With Penn Acoustic Neuroma Quality of Life Scores After Resection of Vestibular Schwannoma: Objective: Determine associations between preoperative caloric testing and video head impulse testing (vHIT) with baseline and postoperative Penn Acoustic Neuroma Quality of Life (PANQOL) scores following resection of vestibular schwannoma (VS).Study Design: Retrospective case series.Setting: Two tertiary referral hospitals.Patients: Adult patients with unilateral VS, preoperative...
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Temporal Bone Anatomy in Superior Semicircular Canal Dehiscence: A Case Control Study on Bone Pneumatization and the Level of Middle Cranial Fossa: Objectives: To assess for any association between the presence of superior semicircular canal dehiscence (SSCD) and temporal bone pneumatization and the height of middle fossa in symptomatic patients.Study Design: Retrospective case-control study.Setting: Tertiary, university referral center.Patients: Symptomatic patients with SSCD and a matched group...
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A New, Promising Experimental Ossicular Prosthesis: A Human Temporal Bone Study With Laser Doppler Vibrometry: Objective: We compared the sound transmission using different types of total ossicular replacement prostheses (TORP); we then studied the performance of a new TORP that we designed inspired by the columella, the single ossicle found in birds.Methods: Stapedial vibrations were measured on nine freshly frozen human temporal bones with laser Doppler vibrometry. We then compared the performances...
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Functional Outcomes Following Temporomandibular Joint Dissection Performed During Surgery for Skull Base Tumors: Background: During skull base tumor surgery, temporomandibular joint (TMJ) dissection is commonly performed. The impact of this procedure on patients' postoperative diet and TMJ function is a matter of concern to surgeons.Methods: We reviewed the Craniomandibular Index (CMI) for 32 patients (15 men and 17 women) who underwent TMJ dissection during surgery for skull base tumors between...
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Long-term Audiometric Outcomes After Atresiaplasty for Congenital Aural Atresia: Objective: Describe long-term trends and stability of hearing outcomes for patients undergoing primary congenital aural atresia (CAA) repair.Study Design: Retrospective chart review.Setting: Single academic, tertiary referral center.Patients: Children and adults who underwent primary CAA repair between 1980 and 2017.Intervention: CAA repair.Main Outcome Measures: Long-term (> 1 yr) postoperative three-tone (500, 1000,...
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Mechanical Energy Dissipation Through the Ossicular Chain and Inner Ear Using Laser Doppler Vibrometer Measurement of Round Window Velocity: Hypothesis: Round window velocity measurements should correlate closely with vibration measurements taken at proximal points along an intact chain over a set frequency range. These round window vibration measurements should be similar to the vibration measurements taken of the ossicles if mechanical energy is conserved through the vestibular organ.Background:...
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Neural Substrates of Tinnitus in an Auditory Brainstem Implant Patient: A Preliminary Molecular Imaging Study Using H2 15 O-PET Including a 5-year Follow-up of Auditory Performance and Tinnitus Perception: Introduction: It was previously demonstrated that tinnitus due to profound unilateral hearing loss can be treated by the use of electrical stimulation via a cochlear implant (CI) with long-lasting positive effects. In cases where patients are not suitable for cochlear implantation due to aplasia/hypoplasia,...
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Hearing Recovery After Ejection of Air in a Case of Traumatic Pneumolabyrinth: Mechanism and Management Options: Objective: To describe a case of traumatic pneumolabyrinth and subsequent hearing recovery after ejection of air with transcanal endoscopic surgical exploration.Patients: A 38-year-old man was struck by his child while cleaning his ear with an ear pick made of bamboo, which penetrated deep into the left ear canal. Severe vertigo with vomiting and left hearing impairment ensued. In addition,...
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Role of Macrophage Migration Inhibitory Factor in NLRP3 Inflammasome Expression in Otitis Media: Hypothesis: Macrophage migration inhibitory factor plays an important role in the expression of interleukin (IL)-1β and the nucleotide-binding oligomerization domain-like receptor protein 3 (NLRP3) inflammasome in lipopolysaccharide-induced otitis media.Background: NLRP3 inflammasome and macrophage migration inhibitory factor are critical molecules mediating inflammation. However, the interaction between...
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Association Between Vestibular Migraine and Migraine Headache: Yet to Explore: Objectives: To evaluate if patients with a diagnosis of vestibular migraine (VM) by the International Classification of Headache Disorders (ICHD) criteria have meaningful differences in symptomatology and disease characteristics when compared to patients with concurrent vestibular symptoms and migraine that do not meet ICHD criteria.Methods: Patients who presented for the evaluation of vertigo were provided a detailed...
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Hyperventilation Syndrome: Investigating the Relationship Between Nijmegen Questionnaire, Vestibular Function Tests, and Patient Symptoms: Objective: To explore the Nijmegen Questionnaire (NQ) and its relationship to vestibular function tests and symptoms in patients with dizziness; to compare patient characteristics between those with a positive Nijmegen score and patients clinically diagnosed with hyperventilation syndrome (HVS).Study Design: Retrospective case series.Setting: Tertiary neurotology...
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The Distribution and Prevalence of Macrophages in the Cochlea Following Cochlear Implantation in the Human: An Immunohistochemical Study Using Anti-Iba1 Antibody: Hypothesis: Cochlear implantation may cause an increase in the number of macrophages in the human cochlea similar to previous findings in the vestibular endorgans.Background: Macrophages play a key role in both an inflammatory response and homeostatic maintenance. Recently, an increase in the prevalence of macrophages was demonstrated in...
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Cerebral Venous Sinus Thrombosis After Translabyrinthine Vestibular Schwannoma—A Prospective Study and Suggested Management Paradigm: Objective: To prospectively evaluate the incidence, risk factors and natural history of postoperative cerebral venous sinus thrombosis (pCVST) in translabyrinthine vestibular schwannoma microsurgical resection and propose a potential management paradigm.Study Design: Prospective, single cohort, multicenter study.Setting: State-wide academic tertiary referral centers.Patients:...
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Postoperative MRI Surveillance of Vestibular Schwannomas: Is There a Standard of Care?: Objective: To examine current practices for postoperative imaging surveillance following vestibular schwannoma resection.Study Design: Cross-sectional survey of practicing neurotologists.Setting: Tertiary referral centers.Patients: Not applicable.Intervention: Two hundred seventy-six members of the American Neurotology Society were invited to participate. Using a web-based format, respondents self-reported demographic...
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Lesion Patterns and Possible Implications for Recovery in Acute Unilateral Vestibulopathy: Objective: To assess patterns of end-organ involvement in acute unilateral vestibulopathy (AUV) and to define the recovery.Study Design: Retrospective chart review.Setting: Tertiary academic referral hospital.Patients and Interventions: Fifty-nine patients fulfilling clinical criteria for AUV and evaluated using the caloric vestibular test, video head impulse test, and both cervical and ocular vestibular evoked...
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Effect of Malnutrition on Hearing Loss in Children: Objective: To characterize the relation between protein-calorie malnutrition (PCM) and hearing loss (HL) in children.Study Design: Retrospective review.Setting: Tertiary referral hospital.Patients: Children in the Audiological and Genetic Database with a diagnosis of protein-calorie malnutrition, marasmus, and/or kwashiorkor.Interventions: None.Main Outcome Measures: Prevalence, type, severity (4-tone pure-tone average, PTA), and progression of...
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The Physiologic Role of Corticosteroids in Ménière's Disease: An Update on Glucocorticoid-mediated Pathophysiology and Corticosteroid Inner Ear Distribution: There are multiple treatment options for Ménière's disease (MD), including dietary modifications, aminoglycoside therapy, and surgery. All have limitations, ranging from limited effectiveness to permanent hearing loss. Corticosteroids have long been used to manage MD due to their relative efficacy and tolerability, but the exact mechanism for...
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Cochlear Implant Data Logs Predict Children's Receptive Vocabulary.: Related ArticlesCochlear Implant Data Logs Predict Children's Receptive Vocabulary.Ear Hear. 2019 Dec 02;:Authors: Busch T, Vermeulen A, Langereis M, Vanpoucke F, van Wieringen AAbstract OBJECTIVES: The data logs of Cochlear Nucleus cochlear implant (CI) sound processors show large interindividual variation in children's daily CI use and auditory environments. This study explored whether these differences are associated...
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Perioral Ruler in Routine Esthetic Surgery: Convenient and Exact: AbstractLip and perioral surgery, like any other esthetic surgery, requires an exact and convenient measurement tool to ensure reliable and reproducible outcomes. Although three-dimensional measuring equipment has proven its effectiveness in measuring facial parameters over the past two decades, it has some drawbacks, including high cost, long scanning times, and non-portability. Thus, digital photography remains the standard tool...
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Vision Loss Associated with Hyaluronic Acid Fillers: A Systematic Review of Literature: AbstractBackgroundWith the global increase in the use of injectable fillers, more cases with serious adverse events such as skin ischemia and vision loss are being reported. This article aims to review the role of HA fillers, as a subgroup separate from fat graft and non-HA fillers, in causing vision loss and to elucidate various features and outcomes of post-HA filler vision loss.MethodsThe preferred reporting...
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Galectin-3 Expression Correlates with Post-surgical Survival in Canine Oral Melanomas.: Related ArticlesGalectin-3 Expression Correlates with Post-surgical Survival in Canine Oral Melanomas.J Comp Pathol. 2019 Nov;173:49-57Authors: Vargas THM, Pulz LH, Ferro DG, Sobral RA, Venturini MAFA, Corrêa HL, Strefezzi RFAbstract Malignant melanomas (MMs) represent 7% of all malignant neoplasms in dogs. Oral melanocytic neoplasms are often malignant and associated with poor prognosis. There are no...
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Redox Activities of Melanins Investigated by Electrochemical Reverse Engineering: Implications for their Roles in Oxidative Stress.: Related ArticlesRedox Activities of Melanins Investigated by Electrochemical Reverse Engineering: Implications for their Roles in Oxidative Stress.J Invest Dermatol. 2019 Dec 04;:Authors: Kim E, Panzella L, Napolitano A, Payne GFAbstract Melanins, the main epidermal pigments of man, have been viewed traditionally as performing photoprotective and antioxidant...
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[Melanoma within tattoos: Two cases and a systematic literature review].: Related Articles[Melanoma within tattoos: Two cases and a systematic literature review].Ann Dermatol Venereol. 2019 Dec 04;:Authors: Cherkaoui El Baraka F, Kluger N, Ollivier I, Bourgoin R, Grossin M, Zeboulon C, Phan C, Sin C, Mahé EAbstract BACKGROUND: There have been reports of malignant melanoma arising within tattoos. However, there is no clear relationship between tattoos and the development of cutaneous malignancies....
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Pembrolizumab in paediatric patients with advanced melanoma or a PD-L1-positive, advanced, relapsed, or refractory solid tumour or lymphoma (KEYNOTE-051): interim analysis of an open-label, single-arm, phase 1-2 trial.: Related ArticlesPembrolizumab in paediatric patients with advanced melanoma or a PD-L1-positive, advanced, relapsed, or refractory solid tumour or lymphoma (KEYNOTE-051): interim analysis of an open-label, single-arm, phase 1-2 trial.Lancet Oncol. 2019 Dec 04;:Authors: Geoerger...
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Lentigo maligna melanoma mapping using reflectance confocal microscopy correlates with staged excision: A prospective study.: Related ArticlesLentigo maligna melanoma mapping using reflectance confocal microscopy correlates with staged excision: A prospective study.J Am Acad Dermatol. 2019 Dec 05;:Authors: Navarrete-Dechent C, Cordova M, Aleissa S, Liopyris K, Dusza SW, Kose K, Busam KJ, Hollman T, Lezcano C, Pulitzer M, Chen CJ, Lee EH, Rossi AM, Nehal KSAbstract BACKGROUND: Lentigo maligna/lentigo...
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A cocktail of polyclonal affinity enriched antibodies against melanoma mutations increases binding and inhibits tumor growth.: Related ArticlesA cocktail of polyclonal affinity enriched antibodies against melanoma mutations increases binding and inhibits tumor growth.J Immunol Methods. 2019 Dec 05;:112720Authors: Shukla GS, Sun YJ, Pero SC, Krag DNAbstract BACKGROUND: Antibodies that target a single tumor antigen fail to cure stage IV cancer patients due to tumor heterogeneity resulting...
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Correlation between referral cytology and in-house colposcopy-guided cytology for detecting early cervical neoplasia.: Related ArticlesCorrelation between referral cytology and in-house colposcopy-guided cytology for detecting early cervical neoplasia.Arch Gynecol Obstet. 2019 Dec 06;:Authors: Schulmeyer CE, Stübs F, Gass P, Renner SK, Hartmann A, Strehl J, Mehlhorn G, Geppert C, Adler W, Beckmann MW, Koch MCAbstract PURPOSE: The current cervical cancer screening program in Germany recommends...
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Factors associated with condom use during sexual intercourse with a new partner among Scandinavian women.: Related ArticlesFactors associated with condom use during sexual intercourse with a new partner among Scandinavian women.Prev Med. 2019 Dec 04;:105944Authors: Tatla MK, Faber MT, Hansen BT, Arnheim-Dahlström L, Munk C, Nygård M, Kjær SKAbstract In this population-based, cross-sectional questionnaire study among 18-45-year-old women from Denmark, Sweden, and Norway conducted during 2011-2012...
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Estimates of incidence and mortality of cervical cancer in 2018: a worldwide analysis.: Related ArticlesEstimates of incidence and mortality of cervical cancer in 2018: a worldwide analysis.Lancet Glob Health. 2019 Dec 04;:Authors: Arbyn M, Weiderpass E, Bruni L, de Sanjosé S, Saraiya M, Ferlay J, Bray FAbstract BACKGROUND: The knowledge that persistent human papillomavirus (HPV) infection is the main cause of cervical cancer has resulted in the development of prophylactic vaccines to prevent...
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Human papillomavirus vaccine against cervical cancer: opportunity and challenge.: Related ArticlesHuman papillomavirus vaccine against cervical cancer: opportunity and challenge.Cancer Lett. 2019 Dec 05;:Authors: Wang R, Pan W, Jin L, Huang W, Li Y, Wu D, Gao C, Ma D, Liao SAbstract Cervical cancer is one of the most common cancers threatening women's health, and the persistent infection of high-risk human papillomavirus (HPV) is closely related to the pathogenesis of cervical cancer and...
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Individuals With Autism Spectrum Disorder Show Altered Event-Related Potentials in the Late Stages of Olfactory Processing.: Related ArticlesIndividuals With Autism Spectrum Disorder Show Altered Event-Related Potentials in the Late Stages of Olfactory Processing.Chem Senses. 2019 Nov 11;:Authors: Okumura T, Kumazaki H, Singh AK, Touhara K, Okamoto MAbstract Atypical sensory reactivities are pervasive among people with autism spectrum disorder (ASD). With respect to olfaction, most previous...
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Metal-containing Particulate Matter and Associated Reduced Olfactory Identification Ability in Children from an Area of High Atmospheric Exposure in Mexico City.: Related ArticlesMetal-containing Particulate Matter and Associated Reduced Olfactory Identification Ability in Children from an Area of High Atmospheric Exposure in Mexico City.Chem Senses. 2019 Nov 19;:Authors: Guarneros M, Rivera CL, Gonsebatt ME, Alcaraz-Zubeldia M, Hummel T, Schriever VA, Valdez B, Hudson RAbstract Air pollution...
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Institutional preparedness to prevent and manage anaesthesia-related 'can't intubate, can't oxygenate' events in Australian and New Zealand teaching hospitals.: Related ArticlesInstitutional preparedness to prevent and manage anaesthesia-related 'can't intubate, can't oxygenate' events in Australian and New Zealand teaching hospitals.Anaesthesia. 2019 Nov 10;:Authors: Rehak A, Watterson LMAbstract It is unclear how the recent local and international focus on systems issues and human factors...
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Accuracy of pediatric cricothyroid membrane identification by digital palpation and implications for emergency front of neck access.: Related ArticlesAccuracy of pediatric cricothyroid membrane identification by digital palpation and implications for emergency front of neck access.Paediatr Anaesth. 2019 Nov 20;:Authors: Fennessy P, Walsh B, Laffey JG, McCarthy KF, McCaul CLAbstract BACKGROUND: Emergency front of neck access in a "can't intubate can't oxygenate" scenario in pediatrics is rare....
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Self-reported mini olfactory questionnaire (Self-MOQ): A simple and useful measurement for the screening of olfactory dysfunction.: Related ArticlesSelf-reported mini olfactory questionnaire (Self-MOQ): A simple and useful measurement for the screening of olfactory dysfunction.Laryngoscope. 2019 Nov 20;:Authors: Zou LQ, Linden L, Cuevas M, Metasch ML, Welge-Lüssen A, Hähner A, Hummel TAbstract OBJECTIVES: Olfactory dysfunction is a common problem. However, too little attention has been paid...
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Critical review of electronic nose and tongue instruments prospects in pharmaceutical analysis.: Related ArticlesCritical review of electronic nose and tongue instruments prospects in pharmaceutical analysis.Anal Chim Acta. 2019 Oct 24;1077:14-29Authors: Wasilewski T, Migoń D, Gębicki J, Kamysz WAbstract Electronic nose (enose, EN) and electronic tongue (etongue, ET) have been designed to simulate human senses of smell and taste in the best possible way. The signals acquired from a sensor...
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Novel GPR120 agonist TUG891 modulates fat taste perception and preference and activates tongue-brain-gut axis in mice.: Related ArticlesNovel GPR120 agonist TUG891 modulates fat taste perception and preference and activates tongue-brain-gut axis in mice.J Lipid Res. 2019 Dec 05;:Authors: Murtaza B, Hichami A, Khan AS, Shimpukade B, Ulven T, Ozdener MH, Khan NAAbstract GPR120 is implicated as a lipid receptor in the oro-sensory detection of dietary fatty acids. However, the effects of GPR120...
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Posterior reversible encephalopathy syndrome in a melanoma patient with dabrafenib and trametinib treatment following immunotherapy.: Related ArticlesPosterior reversible encephalopathy syndrome in a melanoma patient with dabrafenib and trametinib treatment following immunotherapy.J Dtsch Dermatol Ges. 2019 Dec 09;:Authors: Stefanou MI, Gepfner-Tuma I, Brendle C, Kowarik M, Meiwes A, Eigentler T, Müller A, Garbe C, Ziemann U, Tabatabai G, Forschner APMID: 31814289 [PubMed - as supplied by publisher]
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Ultrasound-Guided Orthotopic Implantation of Murine Pancreatic Ductal Adenocarcinoma.: Related ArticlesUltrasound-Guided Orthotopic Implantation of Murine Pancreatic Ductal Adenocarcinoma.J Vis Exp. 2019 Nov 19;(153):Authors: Hay CA, Sor R, Flowers AJ, Clendenin C, Byrne KTAbstract The recent success of immune checkpoint blockade in melanoma and lung adenocarcinoma has galvanized the field of immuno-oncology as well as revealed the limitations of current treatments, as the majority of patients...
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Sentinel Lymph Node Biopsy Was Associated With Favorable Survival Outcomes For Patients With Clinically Node-Negative Asian Melanoma.: Related ArticlesSentinel Lymph Node Biopsy Was Associated With Favorable Survival Outcomes For Patients With Clinically Node-Negative Asian Melanoma.Cancer Manag Res. 2019;11:9655-9664Authors: Chang JW, Huang YL, Chang YY, Lo YF, Ho TY, Huang YT, Chen HW, Wu CEAbstract Purpose: Sentinel lymph node biopsy (SLNB) is the standard management for clinically node-negative...
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Immunohistochemical mismatch repair proteins expression as a tool to predict the melanoma immunotherapy response.: Related ArticlesImmunohistochemical mismatch repair proteins expression as a tool to predict the melanoma immunotherapy response.Mol Clin Oncol. 2020 Jan;12(1):3-8Authors: Ponti G, Pellacani G, Tomasi A, Depenni R, Maccaferri M, Maiorana A, Orsi G, Giusti F, Cascinu S, Manfredini MAbstract In difference to other solid malignancies, the identification of biomarkers for the prediction...
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Post-diagnosis smoking and risk of cardiovascular, cancer, and all-cause mortality in survivors of 10 adult cancers: a prospective cohort study.: Related ArticlesPost-diagnosis smoking and risk of cardiovascular, cancer, and all-cause mortality in survivors of 10 adult cancers: a prospective cohort study.Am J Cancer Res. 2019;9(11):2493-2514Authors: Wang Y, Tao H, Paxton RJ, Wang J, Mubarik S, Jia Y, Wang W, Yu CAbstract Several studies have examined the relationship between smoking and mortality...
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Surgical Technique, Indications, and Outcomes of BIOM-Assisted Transvitreal Biopsy for Uveal Melanoma.: Related ArticlesSurgical Technique, Indications, and Outcomes of BIOM-Assisted Transvitreal Biopsy for Uveal Melanoma.Retina. 2019 Dec 05;:Authors: Snyder LL, Daniels ABAbstract PURPOSE: Controversy exists regarding the best method for biopsy of uveal melanoma. We describe our transvitreal technique and evaluate the safety of this technique as well as the efficacy for obtaining sample...
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Management of rheumatic complications of immune checkpoint inhibitor therapy - an oncological perspective.: Related ArticlesManagement of rheumatic complications of immune checkpoint inhibitor therapy - an oncological perspective.Rheumatology (Oxford). 2019 Dec 01;58(Supplement_7):vii29-vii39Authors: Steven NM, Fisher BAAbstract Immune checkpoint inhibitors (CPIs) are an effective treatment for many cancers but cause diverse immune-related adverse events (IrAEs). Rheumatological IrAEs include...
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Fabrication of chitosan/agarose scaffolds containing extracellular matrix for tissue engineering applications.: Related ArticlesFabrication of chitosan/agarose scaffolds containing extracellular matrix for tissue engineering applications.Int J Biol Macromol. 2019 Dec 06;:Authors: Garakani SS, Khanmohammadi M, Atoufi Z, Kamrava SK, Setayeshmehr M, Alizadeh R, Faghihi F, Bagher Z, Davachi SM, Abbaspourrad AAbstract One of the most effective approaches for treatment of cartilage involves the...
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Neurofilament light is a treatment-responsive biomarker in CLN2 disease.: Related ArticlesNeurofilament light is a treatment-responsive biomarker in CLN2 disease.Ann Clin Transl Neurol. 2019 Dec 08;:Authors: Ru Y, Corado C, Soon RK, Melton AC, Harris A, Yu GK, Pryer N, Sinclair JR, Katz ML, Ajayi T, Jacoby D, Russell CB, Chandriani SAbstract OBJECTIVE: Neuronal ceroid lipofuscinosis type 2 (CLN2 disease) is a rare, progressive, fatal neurodegenerative pediatric disorder resulting from deficiencies...
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Effects of phenytoin spray in prevention of fistula formation following cleft palate repair.: Related ArticlesEffects of phenytoin spray in prevention of fistula formation following cleft palate repair.J Craniomaxillofac Surg. 2019 Nov 27;:Authors: Abdollahi Fakhim S, Nouri-Vaskeh M, Fakhriniya MAAbstract BACKGROUND: The effectiveness of topical phenytoin has been reported for the treatment of oral biopsy ulcers, chemotherapy-induced oral mucositis, and chronic periodontitis. This study...
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Activity of chitosan antifungal denture adhesive against common Candida species and Candida albicans adherence on denture base acrylic resin.: Related ArticlesActivity of chitosan antifungal denture adhesive against common Candida species and Candida albicans adherence on denture base acrylic resin.J Prosthet Dent. 2019 Dec 05;:Authors: Namangkalakul W, Benjavongkulchai S, Pochana T, Promchai A, Satitviboon W, Howattanapanich S, Phuprasong R, Ungvijanpunya N, Supakanjanakanti D, Chaitrakoonthong...
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Stomatitis And Everolimus: A Review Of Current Literature On 8,201 Patients.: Related ArticlesStomatitis And Everolimus: A Review Of Current Literature On 8,201 Patients.Onco Targets Ther. 2019;12:9669-9683Authors: Arena C, Troiano G, Zhurakivska K, Nocini R, Lo Muzio LAbstract Background: Oral toxicities, such as mucositis and stomatitis, are some of the most significant and unavoidable side effects associated with anticancer therapies. In past decades, research has focused on newer targeted...
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Fourth-Generation Cryoablation Based Left Atrial Appendage Isolation for the Treatment of Persistent Atrial Fibrillation: First Case Report.: Related ArticlesFourth-Generation Cryoablation Based Left Atrial Appendage Isolation for the Treatment of Persistent Atrial Fibrillation: First Case Report.Am J Case Rep. 2019 Dec 08;20:1830-1836Authors: Tilz RR, Sano M, Vogler J, Fink T, Eitel C, Heeger CHAbstract BACKGROUND Pulmonary vein isolation (PVI) is an effective treatment strategy for patients...
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Stent implantation for severe pulmonary vein stenosis or occlusion secondary to atrial fibrillation ablation.: Related ArticlesStent implantation for severe pulmonary vein stenosis or occlusion secondary to atrial fibrillation ablation.Int J Cardiol. 2019 Nov 28;:Authors: Li YJ, Pan X, Wang C, He BAbstract BACKGROUND: Catheter interventional treatment of pulmonary vein stenosis or occlusion (PVS/O) following radiofrequency ablation (RFA) for atrial fibrillation (AF) remains a challenging...
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Radiofrequency ablation vs. surgical resection for resectable hepatocellular carcinoma: A systematic review and meta-analysis.: Related ArticlesRadiofrequency ablation vs. surgical resection for resectable hepatocellular carcinoma: A systematic review and meta-analysis.Mol Clin Oncol. 2020 Jan;12(1):15-22Authors: Li JK, Liu XH, Cui H, Xie XHAbstract The treatment of hepatocellular carcinoma (HCC) is a significant challenge. Although radiofrequency ablation (RFA) has emerged as a popular therapeutic...
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Three cases of hepatocellular carcinoma treated 4 times with proton beams.: Related ArticlesThree cases of hepatocellular carcinoma treated 4 times with proton beams.Mol Clin Oncol. 2020 Jan;12(1):31-35Authors: Murakami M, Fukumitsu N, Okumura T, Numajiri H, Murofushi K, Ohnishi K, Mizumoto M, Ishikawa H, Tsuboi K, Sakurai HAbstract HCC may recur following surgery or radiofrequency ablation. Proton beam therapy (PBT) is a type of radiotherapy that achieves excellent local control of HCC without...
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Optimizing Management of Patients with Barrett's Esophagus and Low-grade or No Dysplasia Based On Comparative Modeling: Optimizing Barrett's esophagus management.: Related ArticlesOptimizing Management of Patients with Barrett's Esophagus and Low-grade or No Dysplasia Based On Comparative Modeling: Optimizing Barrett's esophagus management.Clin Gastroenterol Hepatol. 2019 Dec 06;:Authors: Omidvari AH, Ali A, Hazelton WD, Kroep S, Lee M, Naber SK, Lauren BN, Ostvar S, Richmond E, Kong CY, Rubenstein...
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Primary peritoneal carcinoma with late-phase pulmonary metastases: a case report: AbstractBackgroundPrimary peritoneal carcinoma (PPC) is a very rare and aggressive type of malignancy with a poor prognosis.Case presentationA 66-year-old woman was referred to our hospital with two pulmonary nodules that developed after PPC resection and postoperative adjuvant chemotherapy administered 5 years earlier. Computed tomography revealed a 1.3-cm-sized nodule in the left lung with a small airspace in the...
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Distal bypass with a varicose vein graft for critical limb ischemia: report of a case: AbstractBackgroundA saphenous vein complicated with varicose veins is generally thought to be unsuitable for bypass grafting.Case presentationA patient who developed sepsis due to lower limb gangrene was successfully treated by endovascular treatment and bypass surgery using a varicose vein graft. There were no complications, such as occlusion or aneurysm, of the varicose vein graft during the 2-year follow-up...
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Measurement of squamous cell carcinoma antigen 2 in lichen planus patients.: Related ArticlesMeasurement of squamous cell carcinoma antigen 2 in lichen planus patients.J Cosmet Dermatol. 2019 Dec 09;:Authors: Khattab FM, Samir MAAbstract BACKGROUND: Lichen planus (LP) is an autoinflammatory mucocutaneous skin disorder with a multifactorial pathogenesis. Squamous cell carcinoma antigen (SCCA) is a tumor marker recognized as a part of the ovalbumin-serpin family. In patients' serum and skin,...
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The co-occurrence of rare non-ocular phenotypes in patients with inherited retinal degenerations.: Related ArticlesThe co-occurrence of rare non-ocular phenotypes in patients with inherited retinal degenerations.Mol Vis. 2019;25:691-702Authors: Ehrenberg M, Weiss S, Orenstein N, Goldenberg-Cohen N, Ben-Yosef TAbstract Purpose: To describe the coexistence of additional non-ocular genetic diseases in patients diagnosed with inherited retinal degenerations (IRDs). Methods: The study was...
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The Effectiveness of an Oral Sensorimotor Stimulation Protocol for the Early Achievement of Exclusive Oral Feeding in Premature Infants. A Randomized, Controlled Trial.: Related ArticlesThe Effectiveness of an Oral Sensorimotor Stimulation Protocol for the Early Achievement of Exclusive Oral Feeding in Premature Infants. A Randomized, Controlled Trial.Phys Occup Ther Pediatr. 2019 Dec 09;:1-13Authors: Aguilar-Rodríguez M, León-Castro JC, Álvarez-Cerezo M, Aledón-Andújar N, Escrig-Fernández R, Rodríguez...
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MDMADrugDescription3,4-Methylenedioxymethamphetamine, commonly known as ecstasy or molly, is a psychoactive drug primarily used as a recreational drug. The desired effects include altered sensations, increased energy, empathy, and pleasure. When taken by mouth, effects begin in 30 to 45 minutes and last 3 to 6 hours. WikipediaFormula: C11H15NO2Other names: 3,4-MDMA; Ecstasy (E, X, XTC); Molly; MandyOnset of action: 30–45 minutes (by mouth)Duration of action: 4–6 hoursMetabolism: Liver, CYP450 extensively...
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A proof-of-principle study of the short-term effects of MDMA (3,4-methylenedioxymethamphetamine) on tinnitus and neural connectivity.: Related ArticlesA proof-of-principle study of the short-term effects of MDMA (3,4-methylenedioxymethamphetamine) on tinnitus and neural connectivity.Int J Neurosci. 2019 Dec 07;:1-20Authors: Searchfield GD, Poppe TNER, Durai M, Jensen M, Kennedy MA, Maggo S, Miller AL, Park J, Russell BR, Shekhawat GS, Spiegel D, Sundram F, Wise KAbstract BACKGROUND: This...
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Environmental Noise-Induced Effects on Stress Hormones, Oxidative Stress, and Vascular Dysfunction: Key Factors in the Relationship between Cerebrocardiovascular and Psychological Disorders.: Related ArticlesEnvironmental Noise-Induced Effects on Stress Hormones, Oxidative Stress, and Vascular Dysfunction: Key Factors in the Relationship between Cerebrocardiovascular and Psychological Disorders.Oxid Med Cell Longev. 2019;2019:4623109Authors: Hahad O, Prochaska JH, Daiber A, Muenzel TAbstract ...
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Gastrointestinal Motility Issues in Cancer Patients: AbstractPurpose of ReviewThis paper seeks to highlight GI motility disorders that are frequently present in patients with a malignancy. GI dysmotility can occur due to the cancer itself or as a consequence of medical and surgical treatments. Often, symptoms are nonspecific and the diagnosis requires a high index of suspicion. The goal of the paper is to review the common motility problems seen in patients with cancer, their clinical manifestations,...
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Complication Rates Using CASPER Dual-Layer Stents for Carotid Artery Stenting in Acute Stroke: AbstractBackground and PurposeThe number of acute and early stent occlusions after emergency stenting of the internal carotid artery (ICA) in patients with tandem lesions is unclear and only mentioned in a small number of publications, ranging from 0–20%. A recent article by Yilmaz et al. reported a high rate of acute in-stent occlusions of 45% within 72 h after deployment of CASPER dual layer stents.MethodsAll...
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Urinary sulphated glycosaminoglycans excretion in obese patients with type 2 diabetes mellitus treated with metformin.: Related ArticlesUrinary sulphated glycosaminoglycans excretion in obese patients with type 2 diabetes mellitus treated with metformin.Arch Physiol Biochem. 2019 Dec 09;:1-7Authors: Jura-Półtorak A, Olczyk P, Chałas-Lipka A, Komosińska-Vassev K, Kuźnik-Trocha K, Winsz-Szczotka K, Ivanova D, Kiselova-Kaneva Y, Krysik K, Telega A, Olczyk KAbstract Objective: The pattern of...
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