Publication date: October 2020Source: International Immunopharmacology, Volume 87Author(s): Jiannan Yao, Manyu Li, Huiyun Zhang, Yang Ge, Nathaniel Weygant, Guangyu An
Tue Jul 21, 2020 14:18
Publication date: October 2020Source: International Immunopharmacology, Volume 87Author(s): Shan Yu, Xueshibojie Liu, Duo Yu, Changyong E, Jinghui Yang
Tue Jul 21, 2020 14:18
Publication date: Available online 21 July 2020Source: CortexAuthor(s): Kenneth M. Heilman
Tue Jul 21, 2020 14:06
Background/Aim: The worldwide population is increasingly aging. Maxillofacial fractures of the geriatric population have been increased. Evaluation of the demographic variables, causes and the patterns of maxillofacial traumas in the elderly population is the main aim of this study. Materials and Methods: Seven hundred thirteen maxillofacial tomography images which were scanned between 2010 and 2019 were evaluated. Data from 50 patients aged 65 years old and/or older, who were treated...
Fri Jul 17, 2020 03:00
Dermoid cysts (DCs) can occur anywhere in the body. However, DCs on neck or head are not common, which account for about 7% among all kinds of DCs and mostly occur in superficial areas. These cysts are hardly seen in the parotid gland. It is challenging to make accurate diagnosis before surgery because of its rarity and the ambiguous findings on radiology images. Based on a short review of the literature on DCs in the parotid gland, we discussed their clinical features and histopathological and radiological...
Fri Jul 17, 2020 03:00
The focus of secondary rhinoplasty for patients with a cleft lip after facial growth has been on correcting nasal tip asymmetry and distorted cleft-side lower lateral cartilage. However, some patients present with mid-vault asymmetry even after secondary rhinoplasty. The authors propose camouflage procedures for patients with a unilateral cleft lip and without symptoms of nasal airway obstruction. In camouflage procedures, autologous cartilage or acellular dermal matrix was used for onlay grafting...
Fri Jul 17, 2020 03:00
Tonsillectomy is one of the most frequently performed surgical operations in otolaryngology clinics. While postoperative pain is frequently encountered, severe pain such as glossopharyngeal neuralgia is extremely rare. Address correspondence and reprint requests to Banu Atalay Erdogan, MD, Associate Professor, Department of Otolaryngology, VM Medicalpark Pendik Hospital, Pendik, Istanbul, Turkey; E-mail: banuatalay81@gmail.com Received 21 April, 2020 Accepted 10 May, 2020 The authors...
Fri Jul 17, 2020 03:00
No abstract available
Fri Jul 17, 2020 03:00
The pericranium is a vascularized structure that can be used for the treatment of complex scalp and skull defects. It is also utilized as a prophylactic measure to prevent wound complications in high-risk patients. In this study, we looked at the use of the pericranial flap in pediatric patients. A retrospective chart review was done in the American University of Beirut Medical Center from February 2010 to 2020. Ten pediatric patients were identified who required either prophylactic pericranial flap...
Fri Jul 17, 2020 03:00
Angiomyolipoma (AML) is a tumor which commonly affects the kidney. Few authors have been reported AML in the oral cavity. In this clinical report, an AML of the hard palate will be presented in a 48-year-old patient. The AML contains mature adipose tissue, thick-walled blood vessels, and irregular bundle of smooth muscle. The AML is sometimes associated with tuberous sclerosis. Although the renal AMLs are often invasive, they involve regional nodes and may recur, extrarenal AMLs are commonly well...
Fri Jul 17, 2020 03:00
Binder Syndrome occurs in less than 1 per 10,000 live births. Mean features of the syndrome include arhinoid face, abnormal position of the nasal bones, intermaxillary hypoplasia with associated malocclusion, reduced or absent anterior nasal spine, atrophy of the nasal mucosa and absence of the frontal sinus. Treatment of these facial deformities is obviously surgical. In the present work, the authors describe, step by step, their technique in secondary rhinoplasty in a 36-years-old patient affected...
Fri Jul 17, 2020 03:00
The ongoing COVID-19 outbreak has created obstacles to health care delivery on a global scale. Low- and middle-income countries (LMICs), many of which already suffered from unmet surgical and medical needs, are at great risk of suffering poor health outcomes due to health care access troubles brought on by the pandemic. Craniofacial outreach programs (CFOP)—a staple for craniofacial surgeons—have historically provided essential care to LMICs. To date, there has not been literature discussing the...
Fri Jul 17, 2020 03:00
Related Articles Blast Exposure Impairs Sensory Gating: Evidence from Measures of Acoustic Startle and Auditory Event-Related Potentials. J Neurotrauma. 2019 03 01;36(5):702-712 Authors: Papesh MA, Elliott JE, Callahan ML, Storzbach D, Lim MM, Gallun FJ Abstract Many military service members and veterans who have been exposed to high-intensity blast waves experience traumatic brain injury (TBI), resulting in chronic auditory deficits despite...
Tue Jul 21, 2020 13:58
Example of human–primate interface: Highly provisioned Southern pig‐tailed macaques (Macaca nemestrina ) at Lumut Mangrove Park, Malaysia receiving daily food handouts from park visitors shortly before the COVID‐19 lockdown in March 2020 (photo by Susana Almagro). Abstract The emergence of SARS‐CoV‐2 in late 2019 and human responses to the resulting COVID‐19 pandemic in early 2020 have rapidly changed many aspects of human behavior, including our interactions with wildlife. In this commentary,...
Mon Jul 20, 2020 22:57
High resolution manometry (HRM) features of paraesophageal hernia (PEH) were compared to axial hiatus hernias and normal controls, with findings of increased intraluminal intrabolus pressure in the distal esophagus and intragastric pressure with PEH, in addition to short esophageal length. These findings help raise suspicion for the presence of PEH on HRM studies Abstract Background Paraesophageal hernias (PEH) can be associated with obstructive symptoms, but high‐resolution manometry (HRM)...
Mon Jul 20, 2020 15:13
Assessed with the 3D‐Transit system (C), patients with diabetes had prolonged colonic transit time characterized by more retrograde movements and stasis in the cecum (A). The XY plot (B) shows the median segmental colonic transit times in the cecal and ascending colon (Asc), the transversal colon (Tra), the descending colon (Dsc) and the rectosigmoid colon (Sig) in patients with diabetes and gastrointestinal symptoms (DM) and healthy controls (HC). Whiskers marks interquartile range. Abstract...
Mon Jul 20, 2020 14:49
Abstract Objective To evaluate enamel roughness and color after debonding flash-free adhesive precoated brackets and brackets coated with conventional orthodontic adhesives using nonbonded enamel as control. Materials and methods A total of 80 extracted human premolars were divided into the following four groups: group I: APCTM Flash-Free adhesive...
Tue Jul 21, 2020 03:00
Technology in Cancer Research &Treatment, Volume 19, Issue , January-December 2020. The aim of this study is to investigate the role of microRNA-499 (miR-499) in hepatocellular carcinoma tumor growth and the underlying molecular mechanisms. The expression of miR-499 was significantly decreased in hepatocellular carcinoma tissues compared with that in adjacent normal tissues. Furthermore, miR-499 overexpression in HEPG2 cell was related to the tumor growth in nude mice xenograft models. Likewise,...
Tue Jul 21, 2020 12:23
New Findings What is the central question of this study? Delayed cardiovascular responses occur following a single bout of remote ischaemic preconditioning (RIPC). Is heart rate variability (HRV), a surrogate marker of cardiac vagal control, able to detect a delayed effect after a single bout of RIPC? Do repeated bouts of RIPC further alter HRV? What is the main finding and its importance? Indices of HRV indicated a shift in sympathovagal balance toward greater parasympathetic...
Mon Jul 20, 2020 20:59
A mutation extending the length of ATOH1 (Atonal), a basic helix‐loop‐helix transcription factor, is associated with progressive non‐syndromic hearing loss in a five‐generation family, revealed by the HEar‐Seq gene panel. Western blot analysis of wild‐type and mutant ATOH1 proteins demonstrated a significantly slower rate of degradation for mutant compared to the wild‐type protein Abstract Mutations in more than 150 genes are responsible for inherited hearing loss, with thousands of different,...
Mon Jul 20, 2020 18:26
Background Intranasal nebulization is an effective treatment for chronic rhinosinusitis and allergic rhinitis; however, terminal inhalation devices have not been fully studied. We compared the sinonasal aerosol distributions and adverse effects of different inhalation units. Methods A mask, double‐head nozzle, and single‐head nozzle were applied to atomize the methylene blue solution to 3‐dimensional printed models of the pediatric nasal cavity, adult nasal cavity with septal deviation, and...
Mon Jul 20, 2020 21:55
Abstract Objective The conditioned medium of calcined tooth powder (CTP‐CM) is a type of biomimetic mineralized material and well contributing to bone healing and bone formation in vivo . However, little is known about the effect of CTP‐CM on human periodontal ligament stem cells (hPDLSCs) as well as the underlying mechanisms. Methods ALP activity assay was conducted to select the concentration with the highest ALP level, which was used for the following experiments. Cell proliferation...
Tue Jul 21, 2020 12:23
Abstract Objectives Non‐syndromic cleft lip with or withoutpalateis one of the most common birth malformations. TP63 and GREM1 were recently reported to be associated with NSCL/P. However, there were few studies focusedon theirassociationsin non‐syndromic cleft lip only (NSCLO). Design Initial screening and replication in large cohorts were used to locate the susceptible SNPs of TP63 and GREM1 .Firstly, variations were screened among 192 NSCLO cases by the Sanger sequencing. Then, we...
Mon Jul 20, 2020 22:34
Abstract Objective Owing to variations in the exterior appearances of noncancerous diseases in the oral cavity, clinicians may have difficulty diagnosing oral squamous cell carcinoma (OSCC). Tissue biopsy is confirmatory, but invasive. Therefore, reliable tumor markers for OSCC are required. Here, exosomal Alix (exoAlix) levels were measured in serum/salivary samples from patients with OSCC and healthy controls (HCs). Methods Fifty‐seven patients admitted to Nagoya University Hospital from...
Mon Jul 20, 2020 12:46
Abstract SMARCA4 encodes a central ATPase subunit in the BRG1‐/BRM‐associated factors (BAF) or polybromo‐associated BAF (PBAF) complex in humans, which is responsible in part for chromatin remodeling and transcriptional regulation. Variants in this and other genes encoding BAF/PBAF complexes have been implicated in Coffin–Siris Syndrome, a multiple congenital anomaly syndrome classically characterized by learning and developmental differences, coarse facial features, hypertrichosis, and underdevelopment...
Mon Jul 20, 2020 11:48
Background: The incidence and the outcomes of pulmonary embolism (PE) missed during emergency department (ED) workup are largely unknown. Objectives: To describe the frequency, demographics, and outcomes of patients with delayed diagnosis of PE. Methods: We retrospectively compared patients diagnosed with PE during ED workup (early diagnosis) with patients diagnosed with PE thereafter (delayed diagnosis). Electronic health records (EHR) of 123,560 consecutive patients who attended a tertiary hospital...
Tue Jul 21, 2020 11:14
Abstract Top‐down spatial attention can modulate contingent attentional capture, but the underlying mechanism is still not clear. Using variants of spatial cueing paradigms, our previous event‐related potential study showed that peripheral color singleton cues with task‐relevant features captured attention (indexed by cue‐elicited N2pc) even when the targets appeared at central locations, but the magnitude of attentional capture was smaller than when the targets appeared at same peripheral locations....
Mon Jul 20, 2020 18:04
Objectives Although magnetic resonance imaging–based formalized grading schemes for intervertebral disc degeneration offer improved reproducibility compared with purely subjective ratings, their intrarater and interrater reliability are not nearly good enough to be able to detect small to medium effects in clinical longitudinal studies. The aim of this study thus was to develop a method that enables automatic and therefore reproducible and reliable evaluation of disc degeneration based on conventional...
Wed Jul 15, 2020 03:00
Objectives We hypothesized that published performances of algorithms for artificial intelligence (AI) pneumothorax (PTX) detection in chest radiographs (CXRs) do not sufficiently consider the influence of PTX size and confounding effects caused by thoracic tubes (TTs). Therefore, we established a radiologically annotated benchmarking cohort (n = 6446) allowing for a detailed subgroup analysis. Materials and Methods We retrospectively identified 6434 supine CXRs, among them 1652 PTX-positive...
Wed Jul 15, 2020 03:00
Over the past 120 years, continuous developments in medical imaging has improved diagnosis and treatment for many diseases and has thereby improved treatment outcome and quality of life of many patients. The number of computed tomography (CT) examinations is today increasing by 4% per year worldwide, for a total of approximately 300 million CT scans per year. About 40% of CT scans are contrast enhanced. Intravenous iodinated contrast media are commonly used for contrast enhancement in CT scans to...
Wed Jul 15, 2020 03:00
Abstract The mutualism between chemical cues emitted into the air and variations in how primates respond to them using olfaction has demonstrated aspects of species‐specific adaptations. Building on this mutualism we can look at particle deposition as another means to understanding how various environments may have elicited biological changes that enable efficient communication. Research on particle movement and deposition within the nasal cavity is largely based on questions about health as it...
Mon Jul 20, 2020 15:08
Abstract Diet plays an incontrovertible role in primate evolution, affecting anatomy, growth and development, behavior, and social structure. It should come as no surprise that a myriad of methods for reconstructing diet have developed, mostly utilizing the element that is not only most common in the fossil record but also most pertinent to diet: teeth. Twenty years ago, the union of traditional, anatomical analyses with emerging scanning and imaging technologies led to the development of a new...
Mon Jul 20, 2020 11:14
Journal of International Medical Research, Volume 48, Issue 7, July 2020. ObjectiveTo compare the short- and long-term outcomes of radiofrequency ablation (RFA) versus liver resection and chemotherapy for liver metastases from gastric cancer.MethodsWe retrospectively evaluated 50 patients who underwent curative gastrectomy and local treatments for liver metastases (RFA, n = 20; liver resection, n = 20; and chemotherapy, n = 10) from 2008 to 2018.ResultsThe short- and long-term outcomes of each local...
Mon Jul 20, 2020 15:54
Journal of International Medical Research, Volume 48, Issue 7, July 2020. ObjectiveThis study was designed to explore the clinical application of video laryngoscopy in the diagnosis and treatment of throat foreign bodies (FBs).MethodIn total, 1572 patients diagnosed with throat FBs at the Department of Otolaryngology of Nanjing Drum Tower Hospital were retrospectively analysed. The covariables collected were the time from FB ingestion to admission, age, sex, duration of admission, and site of impaction.ResultThe...
Mon Jul 20, 2020 15:54
Journal of International Medical Research, Volume 48, Issue 7, July 2020. Endotoxins and cytokines play an important role in multiple organ failure pathogenesis in patients with severe Gram-negative bacterial infection. We present a clinical case where an oXiris hemofilter was used for continuous renal replacement therapy (CRRT) treatment in a patient with septic shock after liver transplantation. A 35-year-old man with a 20-year history of hepatitis B presented with jaundice, loss of appetite, and...
Mon Jul 20, 2020 15:37
Journal of International Medical Research, Volume 48, Issue 7, July 2020. The Papez circuit is an important brain structure that is closely associated with learning and memory. In this report, we present four patients with anterograde amnesia as the main manifestation induced by Papez circuit infarction. In addition, we review the distribution of the responsible arteries in key and rare regions to investigate the pathogenesis of these infarctions.
Mon Jul 20, 2020 15:30
Journal of International Medical Research, Volume 48, Issue 7, July 2020. ObjectivesWe investigated the endoplasmic reticulum (ER) stress markers C/EBP homologous protein (CHOP) and glucose-regulated protein (GRP) 78, as well as the inflammatory factors nuclear factor (NF)-κB and IκBα, to assess how social defeat stress induces myocardial injury. Furthermore, we evaluated the protective effects of the ER stress inhibitor 4-phenylbutyric acid (PBA) on myocardial injury in mice.MethodsAdult mice were...
Mon Jul 20, 2020 07:40
Tumors are widely recognized to progress through clonal evolution by sequentially acquiring selectively advantageous genetic alterations that significantly contribute to tumorigenesis and thus are termned driv...
Mon Jul 20, 2020 03:00
Brain abscesses are relatively rare, but they are a potentially life-threatening condition. Predictive factors for poor outcome are a young age and the presence of multiple abscesses. We report a case of a 15-...
Tue Jul 21, 2020 03:00
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