Antibiotics, Vol. 9, Pages 431: Environmental Dissemination of Selected Antibiotics from Hospital Wastewater to the Aquatic Environment Antibiotics doi: 10.3390/antibiotics9070431 Authors: Mutshiene Deogratias Ekwanzala Raisibe Florence Lehutso Teddy Kabeya Kasonga John Barr Dewar Maggy Ndombo Benteke Momba The environmental dissemination of selected antibiotics from hospital wastewater into municipal wastewater and lastly to a receiving water body was investigated. Selected...
Tue Jul 21, 2020 03:00
Antibiotics, Vol. 9, Pages 427: Monitoring of Hydrogen Emission from Bacteria in Food, Animals and in the Blood of Humans Suffering from Lyme Disease by A Specific Hydrogen Sensor Antibiotics doi: 10.3390/antibiotics9070427 Authors: Bruno Kolb Lorina Riesterer Anna-Maria Widenhorn Leona Bier A novel straightforward analytical technique was developed to monitor the emission of hydrogen from anaerobic bacteria cultured in sealed headspace vials using a specific hydrogen sensor....
Tue Jul 21, 2020 03:00
Antibiotics, Vol. 9, Pages 429: Antibiotic-Antiapoptotic Dual Function of Clinacanthus nutans (Burm. f.) Lindau Leaf Extracts against Bovine Mastitis Antibiotics doi: 10.3390/antibiotics9070429 Authors: Aussara Panya Hataichanok Pundith Supawadee Thongyim Thida Kaewkod Thararat Chitov Sakunnee Bovonsombut Yingmanee Tragoolpua Mastitis caused by bacterial infection has negative impacts on milk quality and animal health, and ultimately causes economic losses to the dairy...
Tue Jul 21, 2020 03:00
Antibiotics, Vol. 9, Pages 430: Antiviral Action of Native and Methylated Lactoferrin and β-Lactoglobulin against Potato Virus Y (PVY) Infected into Potato Plants Grown in an Open Field Antibiotics doi: 10.3390/antibiotics9070430 Authors: Mahmoud Sitohy Soad Taha Ali Osman Mahmoud Abdel-Hamid Ali Hamed Ashraf Abdelbacki Potato plants are liable to PVY infection without efficient control. Therefore, they were cultivated under greenhouse and open field conditions, artificially...
Tue Jul 21, 2020 03:00
Antibiotics, Vol. 9, Pages 428: In Vitro Evaluation of the Antimicrobial and Immunomodulatory Activity of Culinary Herb Essential Oils as Potential Perioceutics Antibiotics doi: 10.3390/antibiotics9070428 Authors: Marcela Popa Luminița Măruțescu Eliza Oprea Coralia Bleotu Crina Kamerzan Mariana Carmen Chifiriuc Grațiela Grădișteanu Pircalabioru Due to their antimicrobial, immunomodulatory, antioxidant, and regenerative activities, culinary herbs have multiple medicinal...
Tue Jul 21, 2020 03:00
Antibiotics, Vol. 9, Pages 425: Detection of Carbapenem-Resistance Genes in Klebsiella Species Recovered from Selected Environmental Niches in the Eastern Cape Province, South Africa Antibiotics doi: 10.3390/antibiotics9070425 Authors: Kingsley Ehi Ebomah Anthony Ifeanyi Okoh Carbapenemase-producing Enterobacteriaceae (CPE) have been heavily linked to hospital acquired infections (HAI) thereby leading to futility of antibiotics in treating infections and this have complicated public...
Tue Jul 21, 2020 03:00
Antibiotics, Vol. 9, Pages 426: Occurrence, Virulence and Antimicrobial Resistance-Associated Markers in Campylobacter Species Isolated from Retail Fresh Milk and Water Samples in Two District Municipalities in the Eastern Cape Province, South Africa Antibiotics doi: 10.3390/antibiotics9070426 Authors: Aboi Igwaran Anthony Ifeanyi Okoh Campylobacter species are among the major bacteria implicated in human gastrointestinal infections and are majorly found in faeces of domestic animals,...
Tue Jul 21, 2020 03:00
Antioxidants, Vol. 9, Pages 643: Lycopene Protects against Smoking-Induced Lung Cancer by Inducing Base Excision Repair Antioxidants doi: 10.3390/antiox9070643 Authors: Junrui Cheng Baxter Miller Emilio Balbuena Abdulkerim Eroglu Background: Oxidative stress plays a critical role in lung cancer progression. Carotenoids are efficient antioxidants. The objective of this study was to explore the efficacy of all-trans retinoic acid (ATRA) and carotenoids in cigarette smoke-induced...
Tue Jul 21, 2020 03:00
Antioxidants, Vol. 9, Pages 642: Unraveling the Lipidome and Antioxidant Activity of Native Bifurcaria bifurcata and Invasive Sargassum muticum Seaweeds: A Lipid Perspective on How Systemic Intrusion May Present an Opportunity Antioxidants doi: 10.3390/antiox9070642 Authors: Fábio Santos João P. Monteiro Daniela Duarte Tânia Melo Diana Lopes Elisabete da Costa Maria Rosário Domingues Brown seaweeds are known to present components with appealing bioactive properties...
Tue Jul 21, 2020 03:00
Antioxidants, Vol. 9, Pages 641: Redox Imbalances in Ageing and Metabolic Alterations: Implications in Cancer and Cardiac Diseases. An Overview from the Working Group of Cardiotoxicity and Cardioprotection of the Italian Society of Cardiology (SIC) Antioxidants doi: 10.3390/antiox9070641 Authors: Valentina Mercurio Alessandra Cuomo Christian Cadeddu Dessalvi Martino Deidda Daniela Di Lisi Giuseppina Novo Roberta Manganaro Concetta Zito Ciro Santoro Pietro Ameri Paolo...
Tue Jul 21, 2020 03:00
Antioxidants, Vol. 9, Pages 644: Aging and Progression of Beta-Amyloid Pathology in Alzheimer’s Disease Correlates with Microglial Heme-Oxygenase-1 Overexpression Antioxidants doi: 10.3390/antiox9070644 Authors: Fernández-Mendívil Arreola Hohsfield Green Lopez Neuroinflammation and oxidative stress are being recognized as characteristic hallmarks in many neurodegenerative diseases, especially those that portray proteinopathy, such as Alzheimer’s disease (AD)....
Tue Jul 21, 2020 03:00
Antioxidants, Vol. 9, Pages 640: The Interaction between Mitochondrial Oxidative Stress and Gut Microbiota in the Cardiometabolic Consequences in Diet-Induced Obese Rats Antioxidants doi: 10.3390/antiox9070640 Authors: Adriana Ortega-Hernández Ernesto Martínez-Martínez Ruben Gómez-Gordo Natalia López-Andrés Amaya Fernández-Celis Beatriz Gutiérrrez-Miranda María Luisa Nieto Teresa Alarcón Claudio Alba Dulcenombre Gómez-Garre Victoria Cachofeiro Background:...
Tue Jul 21, 2020 03:00
Antioxidants, Vol. 9, Pages 639: Anti-Inflammatory and Antioxidant Effects of Regular Consumption of Cooked Ham Enriched with Dietary Phenolics in Diet-Induced Obese Mice Antioxidants doi: 10.3390/antiox9070639 Authors: Antonio Serrano Antonio González-Sarrías Francisco A. Tomás-Barberán Antonio Avellaneda Amadeo Gironés-Vilaplana Gema Nieto Gaspar Ros-Berruezo Oxidative damage and chronic inflammation have been proven as one of the major factors associated with obesity,...
Tue Jul 21, 2020 03:00
Atmosphere, Vol. 11, Pages 771: Investigating Future Urbanization’s Impact on Local Climate under Different Climate Change Scenarios in MEGA-urban Regions: A Case Study of the Pearl River Delta, China Atmosphere doi: 10.3390/atmos11070771 Authors: Yeung Fung Ren Xu Huang Leng Wong Urbanization is one of the most significant contributing factors to anthropogenic climate change. However, a lack of projected city land use data has posed significant challenges to...
Tue Jul 21, 2020 03:00
Atmosphere, Vol. 11, Pages 770: Disdrometer, Polarimetric Radar, and Condensation Nuclei Observations of Supercell and Multicell Storms on 11 June 2018 in Eastern Nebraska Atmosphere doi: 10.3390/atmos11070770 Authors: Van Den Broeke Disdrometer and condensation nuclei (CN) data are compared with operational polarimetric radar data for one multicell and one supercell storm in eastern Nebraska on 11 June 2018. The radar was located ~14.3 km from the instrumentation location and provided...
Tue Jul 21, 2020 03:00
Atmosphere, Vol. 11, Pages 768: Tornado Risk Climatology in Europe Atmosphere doi: 10.3390/atmos11070768 Authors: Jürgen Grieser Phil Haines Violent tornadoes are rare in Europe but they can have devastating effects. Damage associated with individual tornadoes can reach several billion euros and they have caused hundreds of fatalities. The tornado risk varies considerably over Europe, but so far only a few national maps of tornado risk and one Europe-wide map exist. We show several...
Tue Jul 21, 2020 03:00
Atmosphere, Vol. 11, Pages 769: Statistical Analysis of the CO2 and CH4 Annual Cycle on the Northern Plateau of the Iberian Peninsula Atmosphere doi: 10.3390/atmos11070769 Authors: Isidro A. Pérez M. Luisa Sánchez M. Ángeles García Nuria Pardo Beatriz Fernández-Duque Outliers are frequent in CO2 and CH4 observations at rural sites. The aim of this paper is to establish a procedure based on the lag-1 autocorrelation to form measurement groups, some of which include outliers,...
Tue Jul 21, 2020 03:00
Biology, Vol. 9, Pages 179: Biocontrol Potential of Purified Elicitor Protein PeBL1 Extracted from Brevibacillus laterosporus Strain A60 and Its Capacity in the Induction of Defense Process against Cucumber Aphid (Myzus persicae) in Cucumber (Cucumis sativus) Biology doi: 10.3390/biology9070179 Authors: Khadija Javed Humayun Javed Dewen Qiu The Cucumber aphid (Myzus persicae), a destructive cucumber aphid usually managed by chemical pesticides, is responsible for enormous annual...
Tue Jul 21, 2020 03:00
Biology, Vol. 9, Pages 180: Circadian Photoentrainment in Mice and Humans Biology doi: 10.3390/biology9070180 Authors: Foster Hughes Peirson Light around twilight provides the primary entrainment signal for circadian rhythms. Here we review the mechanisms and responses of the mouse and human circadian systems to light. Both utilize a network of photosensitive retinal ganglion cells (pRGCs) expressing the photopigment melanopsin (OPN4). In both species action spectra and functional...
Tue Jul 21, 2020 03:00
Biology, Vol. 9, Pages 177: Phytoremediation of Cadmium: Physiological, Biochemical, and Molecular Mechanisms Biology doi: 10.3390/biology9070177 Authors: Ali Raza Madiha Habib Shiva Najafi Kakavand Zainab Zahid Noreen Zahra Rahat Sharif Mirza Hasanuzzaman Cadmium (Cd) is one of the most toxic metals in the environment, and has noxious effects on plant growth and production. Cd-accumulating plants showed reduced growth and productivity. Therefore, remediation of this...
Tue Jul 21, 2020 03:00
Biology, Vol. 9, Pages 178: The Relationship between Sperm Oxidative Stress Alterations and IVF/ICSI Outcomes: A Systematic Review from Nonhuman Mammals Biology doi: 10.3390/biology9070178 Authors: Jordi Ribas-Maynou Marc Yeste Albert Salas-Huetos Achieving high embryo quality following IVF and ICSI procedures is a key factor in increasing fertility outcomes in human infertile couples. While the male factor is known to underlie infertility in about 50% of cases, studies performed...
Tue Jul 21, 2020 03:00
Biomedicines, Vol. 8, Pages 231: Asthma and Obesity in Children Biomedicines doi: 10.3390/biomedicines8070231 Authors: Francesco Sansone Marina Attanasi Sabrina Di Pillo Francesco Chiarelli Asthma and obesity are two major chronic diseases in children and adolescents. Recent scientific evidence points out a causative role of obesity in asthma predisposition. However, studies assessing the real impact of excessive weight gain on lung function in children have shown heterogeneous...
Tue Jul 21, 2020 03:00
Biomedicines, Vol. 8, Pages 232: Sex and Gender Influences on Cancer Immunotherapy Response Biomedicines doi: 10.3390/biomedicines8070232 Authors: Azzurra Irelli Maria Maddalena Sirufo Carlo D’Ugo Lia Ginaldi Massimo De Martinis The global burden of cancer is growing and a wide disparity in the incidence, malignancy and mortality of different types of cancer between each sex has been demonstrated. The sex specificity of cancer appears to be a relevant issue in the management...
Tue Jul 21, 2020 03:00
Biomolecules, Vol. 10, Pages 1086: Compound Prunetin Induces Cell Death in Gastric Cancer Cell with Potent Anti-Proliferative Properties: In Vitro Assay, Molecular Docking, Dynamics, and ADMET Studies Biomolecules doi: 10.3390/biom10071086 Authors: Preethi Vetrivel Seong Min Kim Sang Eun Ha Hun Hwan Kim Pritam Bhagwan Bhosale Kalaiselvi Senthil Gon Sup Kim Gastric cancer is the common type of malignancy positioned at second in mortality rate causing burden worldwide...
Tue Jul 21, 2020 03:00
Biomolecules, Vol. 10, Pages 1085: The GDP-Bound State of Mitochondrial Mfn1 Induces Membrane Adhesion of Apposing Lipid Vesicles through a Cooperative Binding Mechanism Biomolecules doi: 10.3390/biom10071085 Authors: Andrés Tolosa-Díaz Víctor G. Almendro-Vedia Paolo Natale Iván López-Montero Mitochondria are double-membrane organelles that continuously undergo fission and fusion. Outer mitochondrial membrane fusion is mediated by the membrane proteins mitofusin 1 (Mfn1) and...
Tue Jul 21, 2020 03:00
Biomolecules, Vol. 10, Pages 1084: The Disordered Cellular Multi-Tasker WIP and Its Protein–Protein Interactions: A Structural View Biomolecules doi: 10.3390/biom10071084 Authors: Chana G. Sokolik Nasrin Qassem Jordan H. Chill WASp-interacting protein (WIP), a regulator of actin cytoskeleton assembly and remodeling, is a cellular multi-tasker and a key member of a network of protein–protein interactions, with significant impact on health and disease. Here, we attempt...
Tue Jul 21, 2020 03:00
Biomolecules, Vol. 10, Pages 1083: Sphingolipid Analysis Indicate Lactosylceramide as a Potential Biomarker of Inflammatory Bowel Disease in Children Biomolecules doi: 10.3390/biom10071083 Authors: Aleksandra Filimoniuk Agnieszka Blachnio-Zabielska Monika Imierska Dariusz Marek Lebensztejn Urszula Daniluk An altered ceramide composition in patients with inflammatory bowel disease (IBD) has been reported recently. The aim of this study was to evaluate the concentrations of...
Tue Jul 21, 2020 03:00
Biomolecules, Vol. 10, Pages 1082: The COP9 Signalosome: A Multi-DUB Complex Biomolecules doi: 10.3390/biom10071082 Authors: Wolfgang Dubiel Supattra Chaithongyot Dawadschargal Dubiel Michael Naumann The COP9 signalosome (CSN) is a signaling platform controlling the cellular ubiquitylation status. It determines the activity and remodeling of ~700 cullin-RING ubiquitin ligases (CRLs), which control more than 20% of all ubiquitylation events in cells and thereby influence virtually...
Tue Jul 21, 2020 03:00
Biomolecules, Vol. 10, Pages 1081: DLBCL Cells with Acquired Resistance to Venetoclax Are Not Sensitized to BIRD-2 But Can Be Resensitized to Venetoclax through Bcl-XL Inhibition Biomolecules doi: 10.3390/biom10071081 Authors: Martijn Kerkhofs Tamara Vervloessem Kinga B. Stopa Victoria M. Smith Meike Vogler Geert Bultynck Anti-apoptotic Bcl-2-family members are frequently dysregulated in both blood and solid cancers, contributing to their survival despite ongoing oncogenic...
Tue Jul 21, 2020 03:00
Biosensors, Vol. 10, Pages 79: Skin-Integrated Wearable Systems and Implantable Biosensors: A Comprehensive Review Biosensors doi: 10.3390/bios10070079 Authors: Daniela Rodrigues Ana I. Barbosa Rita Rebelo Il Keun Kwon Rui L. Reis Vitor M. Correlo Biosensors devices have attracted the attention of many researchers across the world. They have the capability to solve a large number of analytical problems and challenges. They are future ubiquitous devices for disease diagnosis,...
Tue Jul 21, 2020 03:00
Brain Sciences, Vol. 10, Pages 469: Neurophysiological Correlates of a Single Session of Prefrontal tDCS in Patients with Prolonged Disorders of Consciousness: A Pilot Double-Blind Randomized Controlled Study Brain Sciences doi: 10.3390/brainsci10070469 Authors: Manon Carrière Sepehr Mortaheb Federico Raimondo Jitka Annen Alice Barra Maria C. Binda Fossati Camille Chatelle Bertrand Hermann Géraldine Martens Carol Di Perri Steven Laureys Aurore Thibaut Background....
Tue Jul 21, 2020 03:00
Cancers, Vol. 12, Pages 1995: Do Elderly Lung Cancer Patients Aged ≥75 Years Benefit from Immune Checkpoint Inhibitors? Cancers doi: 10.3390/cancers12071995 Authors: Nagio Takigawa Nobuaki Ochi Nozomu Nakagawa Yasunari Nagasaki Masataka Taoka Naruhiko Ichiyama Ayaka Mimura Hidekazu Nakanishi Hiroyuki Kohara Hiromichi Yamane Lung cancer patients ≥75 years represent nearly 40% of all lung cancer patients and continue to increase. If elderly patients have...
Tue Jul 21, 2020 03:00
Cancers, Vol. 12, Pages 1997: Immune Suppressive Effects of Plasma-Derived Exosome Populations in Head and Neck Cancer Cancers doi: 10.3390/cancers12071997 Authors: Inga J. Beccard Linda Hofmann Jan C. Schroeder Sonja Ludwig Simon Laban Cornelia Brunner Ramin Lotfi Thomas K. Hoffmann Edwin K. Jackson Patrick J. Schuler Marie-Nicole Theodoraki Plasma-derived exosomes of head and neck squamous cell carcinoma (HNSCC) patients carry inhibitory factors mediating...
Tue Jul 21, 2020 03:00
Cancers, Vol. 12, Pages 1996: SRC-Family Kinases in Acute Myeloid Leukaemia and Mastocytosis Cancers doi: 10.3390/cancers12071996 Authors: Edwige Voisset Fabienne Brenet Sophie Lopez Paulo de Sepulveda Protein tyrosine kinases have been recognized as important actors of cell transformation and cancer progression, since their discovery as products of viral oncogenes. SRC-family kinases (SFKs) play crucial roles in normal hematopoiesis. Not surprisingly, they are hyperactivated...
Tue Jul 21, 2020 03:00
Cancers, Vol. 12, Pages 1994: Adjuvant Therapy for Melanoma: Past, Current, and Future Developments Cancers doi: 10.3390/cancers12071994 Authors: Alessandro A. E. Testori Silvia Chiellino Alexander C.J. van Akkooi This review describes the progress that the concept of adjuvant therapies has undergone in the last 50 years and focuses on the most recent development where an adjuvant approach has been scientifically evaluated in melanoma clinical trials. Over the past decade the...
Tue Jul 21, 2020 03:00
Cancers, Vol. 12, Pages 1992: Clinico-Biological Features and Clonal Hematopoiesis in Patients with Severe COVID-19 Cancers doi: 10.3390/cancers12071992 Authors: Nicolas Duployez Jordane Demonchy Céline Berthon Julien Goutay Morgan Caplan Anne-Sophie Moreau Anne Bignon Alice Marceau-Renaut Delphine Garrigue Imelda Raczkiewicz Sandrine Geffroy Maxime Bucci Kazali Alidjinou Julie Demaret Myriam Labalette Thierry Brousseau Annabelle Dupont Antoine...
Tue Jul 21, 2020 03:00
Cancers, Vol. 12, Pages 1989: Merkel Cell Polyomavirus T Antigens Induce Merkel Cell-Like Differentiation in GLI1-Expressing Epithelial Cells Cancers doi: 10.3390/cancers12071989 Authors: Thibault Kervarrec Mahtab Samimi Sonja Hesbacher Patricia Berthon Marion Wobser Aurélie Sallot Bhavishya Sarma Sophie Schweinitzer Théo Gandon Christophe Destrieux Côme Pasqualin Serge Guyétant Antoine Touzé Roland Houben David Schrama Merkel cell carcinoma...
Tue Jul 21, 2020 03:00
Cancers, Vol. 12, Pages 1998: Natural Killer Cell Activation Receptor NKp30 Oligomerization Depends on Its N-Glycosylation Cancers doi: 10.3390/cancers12071998 Authors: Ondřej Skořepa Samuel Pazicky Barbora Kalousková Jan Bláha Celeste Abreu Tomáš Ječmen Michal Rosůlek Alexander Fish Arthur Sedivy Karl Harlos Jan Dohnálek Tereza Skálová Ondřej Vaněk NKp30 is one of the main human natural killer (NK) cell activating receptors used in directed immunotherapy....
Tue Jul 21, 2020 03:00
Cancers, Vol. 12, Pages 1991: Ralaniten Sensitizes Enzalutamide-Resistant Prostate Cancer to Ionizing Radiation in Prostate Cancer Cells that Express Androgen Receptor Splice Variants Cancers doi: 10.3390/cancers12071991 Authors: Banuelos Ito Obst Mawji Wang Hirayama Leung Tam Tien Andersen Sadar Blocking androgen receptor (AR) transcriptional activity by androgen deprivation therapy (ADT) improves the response to radiotherapy for intermediate...
Tue Jul 21, 2020 03:00
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