Engineering-Based Approaches to Understanding, Diagnosing, and Treating Inherited Cardiomyopathies

Inherited cardiomyopathies (diseases of the heart muscle) affect roughly one million Americans and are the leading cause of sudden death in young athletes. Identifying and treating at-risk individuals is a complex undertaking that involves many challenges. These include a large proportion of patient families that lack a recognizable genetic marker and uncertainty surrounding the mechanisms that underlie these disorders. We have developed an array of engineering-based tools to address these obstacles in the clinical management of inherited cardiomyopathies.

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