No abstract available
Fri Aug 28, 2020 03:00
No abstract available
Fri Aug 28, 2020 03:00
The trigeminocardiac reflex is a well-described brainstem reflex that clinically manifests as bradycardia, hypotension, or apnea. This physiological phenomenon is extensively reported during open neurosurgical procedures, but very few data exist for trigeminocardiac reflex occurrence during neurointerventional procedures. This systematic review aims to provide aggregated information related to the trigeminocardiac reflex during neurointerventional procedures and to improve understanding of the various...
Fri Aug 28, 2020 03:00
No abstract available
Fri Aug 28, 2020 03:00
Abstract Background To introduce a new method for measurement of surface roughness of the endodontic instrument, before and after instrumentation, using the Field Emission Scanning Electronic Microscope (FE-SEM) combined with the ImageJ software. Methods Twenty J-shape resin blocks were divided into two groups, ten blocks of each group....
Mon Aug 31, 2020 03:00
Abstract Background The purpose of this study was to evaluate the anesthetic effectiveness of a buccal infiltration technique combined with local massage (using 2% lidocaine) in the extraction of mandibular premolars to be utilized as an alternative to the conventional inferior alveolar nerve block. Methods Patients eligible included...
Mon Aug 31, 2020 03:00
Abstract Infraorbital dark circles and tear trough deformity are considered common aesthetic problems. Numerous therapeutic modalities have been suggested with variable outcomes. The aim of this work wasto compare the efficacy of platelet‐poor plasma (PPP) gel versus platelet‐rich plasma (PRP) in infraorbital rejuvenation. A total of 68 females presented with dark circles and/or tear trough deformity were recruited and treated by PPP gel injection in the right infraorbital region (Group A) and PRP...
Sun Aug 30, 2020 11:48
Sun Aug 30, 2020 11:28
Abstract Most of the current dosimetry models of inhaled short-lived radon decay products assume uniform activity distributions along the bronchial airways. In reality, however, both deposition and clearance patterns of inhaled radon progenies are highly inhomogeneous. Consequently, a new deposition-clearance model has been developed that accounts for such inhomogeneities and applied together with biophysical models of cell death and cell transformation. The scope of this study...
Mon Aug 31, 2020 03:00
Abstract There are limited data on the longitudinal frequency and severity of the symptoms and complications of achondroplasia. We undertook a retrospective electronic chart review of 114 patients to develop a more thorough understanding of the lifetime impact of achondroplasia. Craniocervical stenosis (involving the foramen magnum with or without cervical vertebrae C1 and/or C2) was noted in nearly 50% of patients with craniovertebral junction imaging; however, corrective decompression surgery...
Mon Aug 31, 2020 11:15
Abstract Bi‐allelic HOXA1 pathogenic variants clinically manifest as two distinct syndromes, Bosley–Salih–Alorainy syndrome (BSAS) and Athabascan brainstem dysgenesis syndrome, mainly reported in two different populations from Saudi Arabia and southwest North America, respectively. Here we report two siblings of Indian origin with BSAS phenotype caused by a novel homozygous exon 2 HOXA1 pathogenic variants.
Mon Aug 31, 2020 11:13
Typical Ruffini's corpuscles in human glabrous digital skin. Ax: axon; c: capsule; gc: glial core. The dermis contains sensory corpuscles that mediate tactile stimuli. Ruffini's corpuscles are fusiform type II slowly adapting low‐threshold sensors. This study confirms the existence of Ruffini's corpuscles in human digital skin. Human glabrous digital skin contains fewer than 0.3 Ruffini's corpuscles per mm2. Ruffini's corpuscles share the same immunohistochemical profile as other sensors....
Mon Aug 31, 2020 11:28
New England Journal of Medicine, Ahead of Print.
Sun Aug 30, 2020 15:30
New England Journal of Medicine, Ahead of Print.
Sun Aug 30, 2020 12:10
The link between the gut and the brain is a two way street with populations, rules, and directions we are only just figuring out.
Sun Aug 30, 2020 23:17
New Findings What is the central question of this study? What is the absolute level of pre‐exercise glycogen concentration required to augment the exercise‐induced signalling response regulating mitochondrial biogenesis? What is the main finding and its importance? Commencing high‐intensity endurance exercise with reduced pre‐exercise muscle glycogen concentrations confers no additional benefit to the early signalling responses that regulate mitochondrial biogenesis. Abstract...
Sun Aug 30, 2020 19:05
Grade 3 (G3, poorly differentiated) is an important treatment-decision factor in stage II colon cancer, but no unified diagnostic criteria are established. According to previous studies, an intratumoural poorly differentiated area with no glandular formation (POR) that fills the microscopic field of a ×40 objective lens was an essential factor that defined G3. We aimed to prospectively validate this in a randomized controlled study of adjuvant chemotherapy (SACURA trial). We enrolled 991 patients...
Fri Aug 28, 2020 03:00
Sinonasal squamous cell carcinoma (SNSCC) is sometimes associated with high-risk human papillomavirus (HR-HPV) infection and inverted sinonasal papilloma or oncocytic sinonasal papilloma. Frequent mutations of EGFR and KRAS are reported in inverted sinonasal papilloma–related sinonasal squamous cell carcinoma (ISP-SCC) and oncocytic sinonasal papilloma–related SNSCC, respectively. Here, we attempted to determine the prevalence and the prognostic significances of these alterations in SNSCC. We retrospectively...
Fri Aug 28, 2020 03:00
Glandular papilloma (GP) and mixed squamous cell and glandular papilloma (MP) are rare benign pulmonary tumors occurring in the bronchi. Bronchiolar adenoma (BA) was recently characterized as a pulmonary tumor exhibiting alveolar spread. Both GP/MP and BA are composed of a mixture of glandular, ciliated, squamous, and basal cells. We aimed to clarify whether GP/MP and BA represent the same tumor. We evaluated the detailed histologic characteristics of 11 cases involving pulmonary peripheral tumors...
Fri Aug 28, 2020 03:00
Primary female urethral carcinoma is rare. Limited clinicopathologic information has hindered development of staging criteria in this disease. We analyzed 29 primary female urethral carcinoma resections from 3 academic medical centers to characterize histopathologic features, clinical outcomes, and applicability of current and a novel modified staging criteria. We complemented this analysis with review of fully embedded female autopsy urethras to detail anterior and posterior urethral wall histology....
Fri Aug 28, 2020 03:00
Multicolor fluorescent polymeric hydrogels (MFPHs) are three‐dimensionally cross‐linked hydrophilic polymer networks with tunable emission color. Different from the classic fluorescent materials used primarily in dry solid states or solutions, MFPHs exist as highly water‐swollen quasi‐solid state and thus present many promising properties of both solid and solution, including tissue‐like mechanical properties, intrinsic soft and wet nature, fabulous biocompatibility, along with responsive volume,...
Sun Aug 30, 2020 21:44
Abstract Objectives Understanding thoraco‐pelvic integration in Homo sapiens and their closest living relatives (genus Pan) is of great importance within the context of human body shape evolution. However, studies assessing thoraco‐pelvic covariation across Hominoidea species are scarce, although recent research would suggest shared covariation patterns in humans and chimpanzees but also species‐specific features, with sexual dimorphism and allometry influencing thoraco‐pelvic covariation in...
Sun Aug 30, 2020 16:39
Key points Stress triggers and exacerbates the symptoms of functional gastrointestinal disorders, such as delayed gastric emptying and impaired gastric motility. Understanding the mechanisms in which the neural circuits, impaired by stress, are restored may help identify potential targets for more effective therapeutic interventions. Oxytocin administration or release ameliorates the stress induced delayed gastric emptying and motility, however is it unclear whether the effects are mediated...
Sun Aug 30, 2020 16:23
Key points A decreased respiratory arousal threshold is one of the main contributors to obstructive sleep apnoea (OSA) pathogenesis. Several recent studies have sought to find a drug capable of increasing the respiratory arousal threshold without impairing pharyngeal muscle activity to reduce OSA severity, with variable success. Here we show that zolpidem increases the respiratory arousal threshold by ∼15%, an effect size which was insufficient to systematically decrease OSA severity as measured...
Sun Aug 30, 2020 16:19
This course will review new key journal articles on hearing aid technology and provide clinical implications for practicing audiologists.
Mon Aug 31, 2020 07:00
The aim of this systematic review was to identify, evaluate, and provide a current literature about the influence of heritability on the determination of occlusal traits.
Mon Aug 31, 2020 03:00
Abstract Purpose To evaluate the color stability of CAD/CAM complete denture resins. Materials and methods A total of 176 resin specimens were manufactured from conventional heat‐polymerizing (pink: CONHCP: n = 16; tooth‐shade: CONHCT: n = 16), CAD/CAM subtractively manufactured (pink: WIMP: n = 16, AVMP: n = 16, MEMP: n = 16, POMP: n = 16; tooth‐shade: AVMT: n = 16, MEMT: n = 16, POMT: n = 16), and additively manufactured (pink: NDRPP: n = 16; tooth‐shade: NDRPT: n = 16) denture resins;...
Mon Aug 31, 2020 10:31
Abstract The photonic energy of terahertz wave is in the same order of magnitude as the rotational and vibrational energy levels of organic and biological macro‐molecules, so it has unique advantages in detecting cells and biological macro‐molecules. However, in the life environment, the dynamic time scale of cell‐environment interaction and structural conformation change of biological macro‐molecules are within picosecond to millisecond, and water has strong absorption to terahertz wave, which...
Sun Aug 30, 2020 19:48
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