Abstract The current study was aimed to define clinical practice, knowledge and awareness, and best practice regarding dysphagia in children with esophageal atresia with/without tracheoesophageal fistula (EA-TEF) from the perspective of pediatric surgeons in Turkey. Pediatric surgeons practice EA repair were included. A survey related to clinical practice, knowledge and awareness, and best practice regarding dysphagia in EA-TEF was used. The survey was electronically sent to potential...
Mon Aug 31, 2020 03:00
Abstract There is still controversy on evidence supporting compounds that stimulate the transient receptor potential cation channel (TRP) receptor, which can reduce the latency of swallowing reflex. This systematic review aims to evaluate the effectiveness of TRP-stimulating compounds to reduce swallowing reflex time in the elderly. We searched the following databases: PubMed, EMBASE, OVID, Central, Scopus, ISI, CINALH, LILACS, CRD database, and Open grey until June 1st, 2019....
Mon Aug 31, 2020 03:00
Abstract Swallowing disorders can adversely affect quality of life (QOL). To develop the Chinese version of the Swallowing Quality of Life Questionnaire (ChSWAL-QOL) and evaluate its reliability and validity, the ChSWAL-QOL was generated by forward translation of the original SWAL-QOL, backward translation, cultural adaptation, and revision using the Delphi method. The ChSWAL-QOL was administered to 376 patients with dysphagia treated at Peking Union Medical College Hospital between...
Mon Aug 31, 2020 03:00
Abstract We investigated the capacity for dysphagia prognosis prediction using diffusion tensor tractography (DTT) to assess the state of the corticobulbar tract (CBT) during the initial period following lateral medullary infarction (LMI). Twenty patients with LMI and 20 control subjects were recruited for this study. The patients were classified into two subgroups: subgroup A (16 patients with nasogastric tube required for six months or less after LMI onset) and subgroup B (4...
Mon Aug 31, 2020 03:00
We describe fluorescence photoactivation methods to analyze the axonal transport of neurofilaments in single myelinated axons of peripheral nerves from transgenic mice that express a photoactivatable neurofilament protein.
Mon Aug 31, 2020 20:41
I opened my twitter on June 15, to read a non-Black person describe the murder of Oluwatoyin “Toyin” Salau as an “act of god.” They quote retweeted a video of Salau’s speech at a rally. This tweet received tens of thousands of retweets before the original poster deleted it. They claimed that her death amplified the message of her speech, which was about the intersections of state-sanctioned and gendered violence against Black trans people and cis women and girls inside the movement. These are my...
Mon Aug 31, 2020 20:00
Godderis and Luyten1 astutely identified key roles for occupational health professionals amidst the COVID-19 economic downturn. However, in addition to supporting the return to work, and dealing with secondary health effects of the crisis,1 Occupational Health and Safety (OHS) professionals can lead the adaptation of organisations to an altered world of work by focusing on an active agenda with long-term benefits: improving work design.While the lockdowns and growing economic crisis raise challenging...
Mon Aug 31, 2020 19:00
Pancreatic ductal adenocarcinoma (PDAC) is an extremely malignant tumor. The immune profile of PDAC and the immunologic milieu of its tumor microenvironment (TME) are unique; however, the mechanism of how the TME engineers the carcinogenesis of PDAC is not fully understood. This study is aimed at better understanding the relationship between the immune infiltration of the TME and gene expression and identifying potential prognostic and immunotherapeutic biomarkers for PDAC. Analysis of data from...
Mon Aug 31, 2020 17:50
Osteoporosis is characterized by decreased bone mineral density and increased risk of fracture. Raloxifene is one of the treatments of osteoporosis. However, the responses were variable among patients. Previous studies revealed that the genetic variants are involved in the regulation of treatment outcomes. To date, studies that evaluate the influence of genes across all genome on the raloxifene treatment response are still limited. In this study, a total of 41 postmenopausal osteoporosis patients...
Mon Aug 31, 2020 11:35
Objective. Systemic inflammation response index (SIRI) is a new inflammation-based evaluation system that has been reported for predicting survival in multiple tumors, but the prognostic significance of SIRI in cancers has not been evinced. Methods. Eligible studies updated on December 31, 2019, were selected according to inclusion criteria, the literature searching was performed in PubMed, Web of Science, Google Scholar, and Cochrane. Hazard ratios (HRs), and 95% confidence intervals (CIs) were...
Mon Aug 31, 2020 11:20
Summary Background After the Second World War, the populations living in the Karelia area were strictly divided by the border between Finland and Russia. This resulted in the development of starkly different lifestyles, standard of living and exposure to the environment. The remarkable allergy disparity, both in children and adults, calls for immunological explanations. Methods Young people, aged 15‐20 years, in the Finnish (n = 69) and Russian (n = 75) Karelia were studied. Sensitisation...
Mon Aug 31, 2020 18:50
Publication date: November 2020Source: Medical Hypotheses, Volume 144Author(s): Gilligan Gerardo, Piemonte Eduardo, Panico René
Mon Aug 31, 2020 19:12
Abstract A substantial proportion of patients with coronavirus disease 19 (COVID-19) develop severe respiratory failure. Although the exact pathophysiology of severe COVID-19 pneumonia remains unknown and the characteristics of these patients are heterogeneous, the acute respiratory failure often fulfills criteria for acute respiratory distress syndrome (ARDS) and the clinical characteristics are also consistent with what is previously known about ARDS. Cohort studies also report...
Mon Aug 31, 2020 03:00
Abstract The identification of two cell populations displaying different cytologic characteristics in the same fine needle aspiration (FNA), one with an epithelioid appearance and the other spindle cell morphology, is an extremely rare phenomenon and potentially represents a source of diagnostic confusion. Depending on the lineage and relationship of the two cell types, the differential diagnosis is broad and encompasses a wide spectrum of entities. The current case describes the presence of nests...
Mon Aug 31, 2020 17:15
Publication date: November 2020Source: Biomedicine & Pharmacotherapy, Volume 131Author(s): Shyamaladevi Babu, Selvaraj Jayaraman
Mon Aug 31, 2020 17:30
Background and Objectives Treatment of melasma with lasers remains a challenge due to its limited clinical efficacy in addition to high rates of recurrence and side effects. Recently, picosecond lasers have shown favorable results in treatment of benign pigmented lesions. To compare the efficacy and safety of using a 755‐nm picosecond laser for the treatment of melasma in a split‐face manner, having one side treated with a fractionated beam (diffractive lens array [DLA] coupling) and with a full‐beam...
Mon Aug 31, 2020 15:44
Background and Objectives Primary cutaneous amyloidosis (PCA) is a pruritic disease characterized by amyloid deposition in the skin. Interleukin‐31 (IL‐31) is a pruritus‐mediating cytokine. Fractional carbon dioxide (CO2) laser has shown efficacy in the treatment of PCA regarding the clinical appearance, histological pattern, and pruritus. The aim of this study is to assess the effect of fractional CO2 laser on pruritus associated with PCA, and analyze whether this effect is related to IL‐31 and...
Mon Aug 31, 2020 15:38
OBJECTIVE: Acute cerebral infarction (ACI) is the most common type of acute cerebrovascular disease so far, and its incidence rate has been increasing in recent years. At present, the methods of diagnosing ACI in clinic are extremely complicated, and an effective index that can effectively diagnose ACI is urgently needed in clinic. This study is designed to investigate the clinical significance of Follistatin-like protein 1 (FSTL1), Bax and Bcl-2 in ACI. PATIENTS AND METHODS: A total of 84 cases...
Mon Aug 31, 2020 16:25
OBJECTIVE: Intervertebral disc (IVD) degeneration (IDD) is a well-known consequence of low back pain, as characterized by aberrant cell proliferation and apoptosis of nucleus pulposus (NP) cells. In the present study, we aimed to investigate the effect of lncRNA small nucleolar RNA host gene 6 (SNHG6) on deregulated functions of degenerative NP cells. MATERIALS AND METHODS: After the establishment of rat IDD models, the mRNA and protein levels of collagen-I (Col-I) and collagen II (Col-II), and...
Mon Aug 31, 2020 16:26
Cervical cancer (CC) is the fourth most common cancer in women worldwide. Therefore, it is very important to understand cervical carcinogenesis, as well as the molecular mechanisms and signaling pathways involved in this process, in order to develop new strategies that contribute to diagnosis, prognosis and treatment of cervical cancer. Infection by high risk-human papillomavirus (HR-HPV) is a key event in cervical carcinogenesis, as well as, other factors, such as sociodemographics, lifestyle, sexual...
Mon Aug 31, 2020 16:26
The COVID-19 pandemic demands a reassessment of head and neck oncology treatment paradigms by posing several challenges for oncology services, with unprecedented pressure on the regional health care system. Since February 2020 this has severely disrupted health-care services, leading to accumulating clinic caseload and substantial delays for operations. The head and neck cancer services have been faced with the difficult task of managing the balance between infection risk to health-care providers...
Mon Aug 31, 2020 16:25
This study aims to investigate the association between D-dimer and the risk of mortality in coronavirus disease 2019 (COVID-19) patients using a meta-analysis. We found that the D-dimer levels in non-survival patients were significantly higher than those in survival patients (SMD = 0.91, 95% CI = 0.79 to 1.03). In conclusion, the elevated D-dimer levels were associated with an increased risk of mortality in COVID-19 patients. L'articolo D-dimer is associated with the risk of mortality in Coronavirus...
Mon Aug 31, 2020 16:25
OBJECTIVE: Lopinavir/ritonavir has been used for the treatment of Severe Acute Respiratory Syndrome (SARS) and Middle East Respiratory Syndrome (MERS) coronavirus infections. It has been suggested that, based on this experience, this drug should also be studied in SARS-CoV2 infection. MATERIALS AND METHODS: We performed a systematic review of the literature regarding the use of lopinavir/ritonavir for the treatment of these three infections. We systematically searched the PubMed database from inception...
Mon Aug 31, 2020 16:25
During these challenging and unprecedented times for the global communities as they battle the COVID-19 pandemic, we found a simple and effective way to prevent the goggles fogging. We hope that it will help the healthcare professionals who are still troubled by the problem of fogging goggles. L'articolo Measures to prevent goggles from fogging during the treatment of Coronavirus Disease 2019 sembra essere il primo su European Review.
Mon Aug 31, 2020 16:25
OBJECTIVE: After massive weight loss, patients that meet specific criteria can be inserted in an ad-hoc post-bariatric surgery list in order to be subjected to body contouring procedures. During COVID-19 pandemic, the Italian National Health System has been overwhelmed by the continue load of life-threatening patients that needed medical assistance. Plastic surgery practice enormously scaled back during this period and this fact greatly affected elective procedures waiting lists. The aim of our study...
Mon Aug 31, 2020 16:25
Some surface proteins of the newly identified severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can bind to the hemoglobin molecule of an erythrocyte, which leads to the destruction of the structure of the heme and the release of harmful iron ions to the bloodstream. The degradation of hemoglobin results in the impairment of oxygen-carrying capacity of the blood, and the accumulation of free iron enhances the production of reactive oxygen species. Both events can lead to the development...
Mon Aug 31, 2020 16:25
OBJECTIVE: COVID-19 immune syndrome is a multi-systemic disorder induced by the COVID-19 infection. Pathobiological transitions and clinical stages of the COVID-19 syndrome following the attack of SARS-CoV-2 on the human body have not been fully explored. The aim of this review is to outline the three critical prominent phase regarding the clinicogenomics course of the COVID-19 immune syndrome. MATERIALS AND METHODS: In the clinical setting, the COVID-19 process presents as “asymptomatic/pre-symptomatic...
Mon Aug 31, 2020 16:25
Publication date: Available online 31 August 2020Source: Pathology - Research and PracticeAuthor(s): Yifei Ma, Zhengpeng Gong, Huigang Wang, Ya Liang, Xin Huang, Guodong Yu
Mon Aug 31, 2020 16:30
Publication date: 15 January 2021Source: Talanta, Volume 222Author(s): Nádia Nunes, Iva Popović, Elder Abreu, Dina Maciel, João Rodrigues, Juan Soto, Manuel Algarra, Marijana Petković
Mon Aug 31, 2020 16:26
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