Nature Communications, Published online: 31 August 2020; doi:10.1038/s41467-020-17828-8Humans can unconsciously learn to gamble on rewarding options, but can they do so when it comes to their own mental states? Here, the authors show that participants can learn to use unconscious representations in their own brains to earn rewards, and that metacognition correlates with their learning processes.
Nature Communications, Published online: 31 August 2020; doi:10.1038/s41467-020-18128-xThe pathophysiological role of dopamine D1 receptor (D1R) in chronic heart failure remains elusive. Here the authors show that D1R-expressing cardiomyocytes appear in chronic heart failure and play a pivotal role in triggering lethal ventricular arrhythmias.
Nature Communications, Published online: 31 August 2020; doi:10.1038/s41467-020-18196-zGlobal largest agricultural ammonia (NH3) emissions in China have caused severe damage to both ecosystem and human health, yet no policy is formulated to reduce NH3 emissions. Here, the authors show that halving agricultural NH3 emissions with feasible technical mitigation options in China generates far more societal benefits than abatement costs.
Nature Communications, Published online: 31 August 2020; doi:10.1038/s41467-020-18184-3Salt levels in culture affect the polarisation of Th17 cells, which normally protect the host from fungal and bacterial infections. Here, the authors study patients with salt-losing tubulopathies (SLT) to find that, while Th17 immunity is dampened in SLT patients, their Th17-inducing signaling pathways are intact and can be reinvigorated by exogenous salt.
Nature Communications, Published online: 31 August 2020; doi:10.1038/s41467-020-18231-zThe cellular and molecular mechanisms regulating hypothalamic patterning and differentiation are unclear. Here, the authors profiled the transcriptome of the developing hypothalamus at single cell level, providing a resource to hypothalamic development in health and disease.
Nature Communications, Published online: 31 August 2020; doi:10.1038/s41467-020-18210-4Motor commands for human locomotion are generated by combination of muscle synergies. In humans, muscle synergies for running exhibit considerable plasticity during child-to-adult development and adult training to meet the constantly changing biomechanical and efficiency demands.
Nature Communications, Published online: 31 August 2020; doi:10.1038/s41467-020-18175-4During embryonic development, neural progenitor cells undergo numerous cell divisions. Here, the authors show that ABHD4-mediated developmental anoikis distinguishes the physiological delamination and the pathological detachment of progenitor cells with relevance to fetal alcohol-induced apoptosis.
Nature Communications, Published online: 31 August 2020; doi:10.1038/s41467-020-18199-wTheta range oscillations in the basolateral amygdala (BLA) and the medial prefrontal cortex (mPFC) are associated with conditioned fear. Here, the authors use exogenous oscillatory stimulation of the BLA and mPFC in mice to determine the dynamic roles of theta-range oscillatory states across conditioned fear and extinction learning.
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