Publication date: Available online 2 June 2020Source: Journal of ProteomicsAuthor(s): Bindu Nanduri, Cathy R. Gresham, Winnie W. Hui, Mark Ou, Richard H. Bailey, Mariola J. Edelmann
Wed Jun 03, 2020 15:18
Abstract Purpose To evaluate the effect of chronic alcoholism on morphometry and apoptosis mechanism and correlate with miRNA-21 expression in the corpus cavernosum of rats. Methods Twenty-four rats were divided into two experimental groups: Control (C) and Alcoholic group (A). After two weeks of an adaptive phase, rats from group A received only ethanol solution (20%) during 7 weeks. The morphometric and caspase-3 immunohistochemistry analysis were performed in the corpus cavernosum. The miRNA-21...
Wed Jun 03, 2020 15:18
Abstract Background Talent identification and development (TID) programs aim to identify players with the greatest potential for long-term success. Previous research suggests that the assessment of sport-specific technical skills is valuable for discriminating between more and less skilled individuals and/or for predicting future performance. Objective ...
Wed Jun 03, 2020 03:00
Abstract Coaches and athletes in elite sports are constantly seeking to use innovative and advanced training strategies to efficiently improve strength/power performance in already highly-trained individuals. In this regard, high-intensity conditioning contractions have become a popular means to induce acute improvements primarily in muscle contractile properties, which are supposed to translate to subsequent power performances. This performance-enhancing physiological mechanism...
Wed Jun 03, 2020 03:00
Idiopathic pulmonary fibrosis (IPF), the most frequent form of irreversible interstitial pneumonia with unknown etiology, is characterized by massive remodeling of lung architecture and followed by progressive loss of lung function. However, the key regulatory genes and the specific signaling pathways involved in the onset and progression of IPF still remain unclear. The present study is aimed at investigating the key role of long noncoding RNAs (lncRNAs) and transcription factors (TFs) involved...
Wed Jun 03, 2020 08:50
Objective. To establish a novel nomogram for diagnosing liver fibrosis in patients with chronic hepatitis B virus (HBV) infection and verify the diagnostic performance of the established nomogram. Methods. Patients with chronic HBV infection who met the inclusion and exclusion criteria were enrolled in this retrospective study; 70% and 30% of patients were randomly assigned to training dataset and validation dataset, respectively. The risk factors for liver fibrosis were screened using the univariate...
Wed Jun 03, 2020 06:50
35 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: human homeostasis These pubmed results were generated on 2020/06/03PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Wed Jun 03, 2020 14:31
Publication date: Available online 3 June 2020Source: Journal of VoiceAuthor(s): Angélica Emygdio da Silva Antonetti, Vanessa Veis Ribeiro, Alcione Ghedini Brasolotto, Kelly Cristina Alves Silverio
Wed Jun 03, 2020 15:13
Abstract Background Bacterial biofilms adhere to all tissues and surfaces in the oral cavity. Oral biofilms are responsible for the decay of human dental structures and the inflammatory degeneration of the alveolar bone. Moreover, oral biofilms on artificial materials influence the lifespan of dental prostheses and restoratives. Methods ...
Wed Jun 03, 2020 03:00
Abstract Background To evaluate tooth discoloration by newly developed calcium silicate-based materials, and to examine the pre-application of dentin bonding agent (DBA) for preventing discoloration caused by mineral trioxide aggregate (MTA). Methods The roots of 50 premolars were randomly divided into five groups (n = 10) and cavities...
Wed Jun 03, 2020 03:00
Abstract Background Dental caries in primary teeth is a serious oral health concern among children. It can lead to detrimental impacts on a child’s growth, development, and quality of life. Therefore, this cross-sectional study aimed to examine the prevalence of dental caries and its associations with nutritional status, sugar and second-hand smoke exposure among pre-schoolers. ...
Wed Jun 03, 2020 03:00
Abstract Background The aim of this in vitro study was to examine the possible enhancement of the biofilm peeling effect of a sonic toothbrush following the use of an antimicrobial mouth rinse. Methods The biofilm at a noncontact site in the interdental area was treated by sound wave convection with the test solution or by immersion in...
Wed Jun 03, 2020 03:00
Abstract Background The use of silver-formulation as microbicide to arrest dentinal caries is gaining popularity. The primary objective of the present appraisal was to systematically review the clinical (in vivo) applications and antimicrobial potential of silver-containing formulations in arresting dentinal caries. Our secondary aim was to sum up the available in vitro applications of silver-containing formulations against cariogenic...
Wed Jun 03, 2020 03:00
Abstract Multiphoton microscopy (MPM) is a promising non‐invasive imaging tool for discriminating benign nevi from melanoma. In this study, we establish a MPM morphologic catalogue of common nevi, information that will be critical in devising strategies to distinguish them from nevi that are evolving to melanoma that may present with more subtle signs of malignancy. Thirty common melanocytic nevi were imaged in vivo using MPM. Quantitative parameters that can distinguish between different types...
Tue Jun 02, 2020 11:27
Related ArticlesRegular Sunscreen Use and Risk of Mortality: Long-Term Follow-up of a Skin Cancer Prevention Trial. Am J Prev Med. 2019 05;56(5):742-746 Authors: Lindstrom AR, von Schuckmann LA, Hughes MCB, Williams GM, Green AC, van der Pols JC Abstract INTRODUCTION: Sunscreen is widely used to protect the skin from harmful effects of sun exposure. However, there are concerns that sunscreens may negatively affect overall health. Evidence of the general...
Wed Jun 03, 2020 15:11
Related ArticlesLumbo-peritoneal shunt as treatment modality for visual symptoms in idiopathic intracranial hypertension: A single institution experience. Neurocirugia (Astur). 2020 May 29;: Authors: Krishnan SS, Nigam P, Manuel A, Vasudevan MC Abstract OBJECTIVES: To evaluate the efficacy of lumbo-peritoneal shunt (LPS) in patients of idiopathic intracranial hypertension presenting with visual symptoms. METHODS: Between Apr. 2014 and Mar. 2018,...
Wed Jun 03, 2020 15:08
Publication date: Available online 3 June 2020Source: American Journal of Infection ControlAuthor(s): Jie Peng, Xunlian Wu, Rongli Wang, Cui Li, Qing Zhang, Daiqing Wei
Wed Jun 03, 2020 15:05
Publication date: Available online 2 June 2020Source: American Journal of Infection ControlAuthor(s): Hidetoshi Nomoto, Masahiro Ishikane, Daisuke Katagiri, Noriko Kinoshita, Mami Nagashima, Kenji Sadamasu, Kazuhisa Yoshimura, Norio Ohmagari
Wed Jun 03, 2020 15:05
Publication date: Available online 2 June 2020Source: Pathology - Research and PracticeAuthor(s): Theodore Vougiouklakis, Brendan J. Belovarac, Andrew Lytle, Luis Chiriboga, Ugur Ozerdem
Wed Jun 03, 2020 15:05
Publication date: Available online 2 June 2020Source: Pathology - Research and PracticeAuthor(s): Hyeongjoo Kim, Taewan Kim, Gunn Jaygal, Jongsoo Woo, Chang-Jin Kim, Moo-Jun Baek, Dongjun Jeong
Wed Jun 03, 2020 15:05
Publication date: Available online 2 June 2020Source: Pathology - Research and PracticeAuthor(s): Qian Wu, Weiya Wang, Ping Zhou, Yiyun Fu, Ying Zhang, Yang W. Shao, Lili Jiang
Wed Jun 03, 2020 15:05
Publication date: Available online 2 June 2020Source: Photodiagnosis and Photodynamic TherapyAuthor(s): Sandra Bastos Rezende, Luana Campos, Luiz Felipe Palma, Ricardo Yudi Tateno, Alyne Simões, Maria Cristina Macedo, Roberto Luiz da Silva
Wed Jun 03, 2020 15:05
Publication date: Available online 3 June 2020Source: Annals of Allergy, Asthma & ImmunologyAuthor(s): Sarah J. Smith, Elissa M. Abrams, Anita Kozyrskyj, Allan Becker, Jennifer LP. Protudjer
Wed Jun 03, 2020 15:04
Publication date: Available online 3 June 2020Source: Seminars in OncologyAuthor(s): Elaine M. Walsh, Karen L. Smith, Vered Stearns
Wed Jun 03, 2020 15:03
In this study we analysed the impact of water regime and soil nutrients on the clonal diversity and genetic variation of the sedge Carex nigra in a central alpine fen. For our analysis, we established 16 study plots randomly distributed over the fen. We determined the exact elevation of each plot as an indicator for the water regime and measured the content of phosphorous and potassium in the soil of each plot. Clonal diversity and genetic variation of C. nigra were assessed with nuclear microsatellites...
Wed Jun 03, 2020 03:00
Background Colorectal cancer is the second leading cause of cancer death. Almost half of the patients present recurrence within 5 years after the treatment of the primary tumor, the majority, with metastasis. On the other hand, in the search for new animal models that simulate metastatic cancer, it has been suggested that fibroblasts immersed in the peritumoral stroma (cancer-associated fibroblasts (CAFs)), play a relevant role in the development of cancer. The objective of this study was to identify...
Wed Jun 03, 2020 03:00
A practical limitation to many metabarcoding initiatives is that sampling methods tend to collect many non-target taxa, which become “amplicon noise” that can saturate Next Generation Sequencing results and lead to both financial and resource inefficiencies. An available molecular tool that can significantly decrease these non-target amplicons and decrease the need for pre-DNA-extraction sorting of bycatch is the design of PCR primers tailored to the taxa under investigation. We assessed whether...
Wed Jun 03, 2020 03:00
Background As the major bioactive compounds in citrus and grape, it is significant to use the contents of flavonoids and phenolic acids as quality evaluation criteria to provide a better view of classifying the quality and understanding the potential health benefits of each fruit variety. Methods A total of 15 varieties of citrus and 12 varieties of grapes were collected from Fujian, China. High-performance liquid chromatography method was used for the simultaneous determination of 17...
Wed Jun 03, 2020 03:00
Background Biobanking of cell lines is a promising tool of support for wildlife conservation. In particular, the ability to preserve fibroblast cell lines derived from collared peccaries is of significance as these wild mammals are unique to the Americas and play a large role in maintaining the ecosystem. We identified collared peccary fibroblasts by immunofluorescence and evaluated their morphology, growth and adherence capacity. Further, we monitored the viability and metabolic activity of the...
Wed Jun 03, 2020 03:00
Background Previous studies have indicated that chronic inflammation linked to H. pylori infection is the leading causes for gastric cancer (GC). However, the exact mechanism is not entirely clear until now. Purpose To identify the key molecules and TFs involved in H. pylori infection and to provide new insights into H. pylori-associated carcinogenesis and lay the groundwork for the prevention of GC. ...
Wed Jun 03, 2020 03:00
Species distribution models (SDMs) are used to interpret and map fish distributions based on habitat variables and other drivers. Reef fish avoidance behavior has been shown to vary in the presence of divers and is primarily driven by spearfishing pressure. Diver avoidance behavior or fish wariness may spatially influence counts and other descriptive measures of fish assemblages. Because fish assemblage metrics are response variables for SDMs, measures of fish wariness may be useful as predictors...
Wed Jun 03, 2020 03:00
Ecosystem models require the specification of initial conditions, and these initial conditions have some level of uncertainty. It is important to allow for uncertainty when presenting model results, because it reduces the risk of errant or non-representative results. It is crucial that model results are presented as an envelope of what is likely, rather than presenting only one instance. We perturbed the initial conditions of the Chatham Rise Atlantis model and analysed the effect of this uncertainty...
Wed Jun 03, 2020 03:00
Background Lower-grade gliomas (LGGs) is characteristic with great difference in prognosis. Due to limited prognostic biomarkers, it is urgent to identify more molecular markers to provide a more objective and accurate tumor classification system for LGGs. Methods In the current study, we performed an integrated analysis of gene expression data and genome-wide methylation data to determine novel prognostic genes and...
Wed Jun 03, 2020 03:00
Background Melanoma is a highly invasive malignant skin tumor. While melanoma may share some similarities with that of melanocytic nevi, there also exist a number of distinct differences between these conditions. An analysis of these differences may provide a means to more effectively evaluate the etiology and pathogenesis of melanoma. In particular, differences in aberrant methylation expression may prove to represent a critical distinction. ...
Wed Jun 03, 2020 03:00
Background Carbon (C), nitrogen (N) and phosphorus (P) stoichiometric ratios are important indicators of ecosystem function and productivity. However, few studies have assessed the nutrient relationship between plant, litter and soil, and the nutrient stock in different secondary mixed forest types. Methods We investigated the C, N and P concentrations and stoichiometric ratios in trees, understory plants, litter and soil layers in three different secondary mixed forest types (broadleaf...
Wed Jun 03, 2020 03:00
Background Paclitaxel (PTX) resistance is a major obstacle in the treatment of triple-negative breast cancer (TNBC). Previously, we have reported that interleukin-1 receptor-associated kinase 1 (IRAK1) and its downstream pathways are associated with PTX resistance in TNBC cells. In this study, we sought to investigate the combination treatment of ginsenoside panaxatriol (GPT), one of the main active components in Panax ginseng, with PTX on viability and apoptosis of TNBC PTX resistant cells, and...
Wed Jun 03, 2020 03:00
Cardiovascular factors are associated with the pathophysiological features and risk of sudden sensorineural hearing loss (SSNHL). However, little is known about the link between carotid intima-media thickness (IMT), SSNHL risk, and their respective treatment outcomes. In this study, we retrospectively reviewed 47 SSNHL cases and 33 control subjects from a single medical center and compared their demographic data and clinical characteristics, including their carotid IMT and audiological data. Of the...
Wed Jun 03, 2020 03:00
Background Highly sensitive real-time reverse transcription polymerase chain reaction (RT-qPCR) methods have been developed for the detection of SARS-CoV-2. However, they are costly. Loop-mediated isothermal amplification (LAMP) assay has emerged as a novel alternative isothermal amplification method for the detection of nucleic acid. Methods A rapid, sensitive and specific real-time reverse transcription LAMP (RT-LAMP) assay was developed for SARS-CoV-2 detection. Results This...
Wed Jun 03, 2020 03:00
Background Despite the widespread use of antibodies as a research tool, problems with specificity, lot-to-lot consistency and sensitivity commonly occur and may be important contributing factors to the ‘replication crisis’ in biomedical research. This makes the validation of antibodies and accurate reporting of this validation in the scientific literature extremely important. Therefore, some journals now require authors to comply with antibody reporting guidelines. ...
Wed Jun 03, 2020 03:00
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