Medicine by Alexandros G.Sfakianakis

Bone microRNA-21 as surgical stress parameter is associated with third molar postoperative discomfort

Abstract Objective To evaluate an association between bone levels of inflammation/oxidative stress mediators and postoperative discomfort after third molar conventional or piezosurgery. Material and methods Twenty-six subjects with bilaterally impacted mandibular third molars, who underwent either piezo or conventional surgery, were included in a split-mouth...

Resistance to β-lactams and distribution of β-lactam resistance genes in subgingival microbiota from Spanish patients with periodontitis

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Abstract Objectives The aim of this study was to analyze the distribution of β-lactamase genes and the multidrug resistance profiles in β-lactam-resistant subgingival bacteria from patients with periodontitis. Materials and methods Subgingival samples were obtained from 130 Spanish patients with generalized periodontitis stage III or IV. Samples were grown...

Fusion of intra-oral scans in cone-beam computed tomography scans

Wed Jun 03, 2020 03:00

Abstract Purpose The purpose of this study was to evaluate the clinical accuracy of the fusion of intra-oral scans in cone-beam computed tomography (CBCT) scans using two commercially available software packages. Materials and methods Ten dry human skulls were subjected to structured light scanning, CBCT scanning, and intra-oral scanning. Two commercially...

Targeted sensitization of tumor cells for radiation through monocarboxylate transporters 1 and 4 inhibition in vitro

Wed Jun 03, 2020 03:00

Abstract Objectives Monocarboxylate transporters (MCT) 1, 2 and 4 play an important role in tumor metabolism. The amount of lactate transported by MCT’s highly correlates with overall survival. Furthermore, glycolysis and hypoxia are possible causes for radiation resistance. Materials and methods An oral squamous cell carcinoma cell line (CAL27, ATCC) was...

The New England Journal of Medicine: Search Results in Primary Care\Hospitalist\Clinical Practice

Wed Jun 03, 2020 03:00

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Universal Masking in the Covid-19 Era

We understand that some people are citing our Perspective article (published on April 1 at NEJM.org) as support for discrediting widespread masking. In truth, the intent of our article was to push for more masking, not less. It is apparent that many people with SARS-CoV-2 infection are asymptomatic…

The New England Journal of Medicine: Search Results in Primary Care\Hospitalist\Clinical Practice

Wed Jun 03, 2020 03:00

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Royal Society of Chemistry (Great Britain) Society for Analytical Chemistry Society of Public Analysts (Great Britain)

Enzyme-free amplified detection of miRNA based on target-catalyzed hairpin assembly and DNA-stabilized fluorescent silver nanoclusters

Analyst, 2020, Accepted ManuscriptDOI: 10.1039/D0AN00545B, PaperJinqing Gu, Zhenzhen Qiao, Xiaoxiao He, Yanru Yu, Yanli Lei, Jinlu Tang, Hui Shi, Dinggeng He, Kemin WangMicroRNAs (miRNAs) have been shown to be promising biomarkers for disease diagnostics and therapeutics. However, rapid, low-cost, sensitive, and selective detection of miRNAs remains a challenge because of their characters...The content of this RSS Feed (c) The Royal Society of Chemistry

Royal Society of Chemistry (Great Britain) Society for Analytical Chemistry Society of Public Analysts (Great Britain)

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Recent advances in sensors for electrochemical analysis of nitrate in food and environmental matrices

Analyst, 2020, Accepted ManuscriptDOI: 10.1039/D0AN00823K, Critical ReviewChunbo Jiang, Yinghe He, Yang LiuNitrate is one of the most common contaminants in food and the environment, which mainly arises from the intense human activities. Electrochemical sensors have been considered as one of the...The content of this RSS Feed (c) The Royal Society of Chemistry

Royal Society of Chemistry (Great Britain) Society for Analytical Chemistry Society of Public Analysts (Great Britain)

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Fe3+ detection, bioimaging, and patterning based on bright blue-fluorescent N-doped carbon dots

Analyst, 2020, Accepted ManuscriptDOI: 10.1039/D0AN01042A, PaperLin Li, Lihong Shi, Jing Jia, Chuan Dong, Shaomin Shuang, Dan ChangThe bright blue fluorescent N-doped carbon dots (N-CDs) with satisfactory yield (54%) was successfully fabricated by one-step hydrothermal treatment of astragalus. The obtained N-CDs possessed superior stability, favorite solubility and...The content of this RSS Feed (c) The Royal Society of Chemistry

Royal Society of Chemistry (Great Britain) Society for Analytical Chemistry Society of Public Analysts (Great Britain)

Wed Jun 03, 2020 02:00

Ultrasensitive Detection of Butyrylcholinesterase Activity based on the Inner Filter Effect of MnO2 Nanosheets on Sulfur Nanodots

Analyst, 2020, Accepted ManuscriptDOI: 10.1039/D0AN00939C, PaperTianzi Li, Yetong Gao, Huiya Li, Chenyang Zhang, Yifei Xing, Meng Jiao, Yu-e Shi, Wei Li, Zhai Yongqing, Zhenguang WangButyrylcholinesterase (BChE) activity is an important index for a variety of diseases. In this work, a “turn-on” assay is proposed based on controlling the inner filter effect (IFE) of MnO2...The content of this RSS Feed (c) The Royal Society of Chemistry

Royal Society of Chemistry (Great Britain) Society for Analytical Chemistry Society of Public Analysts (Great Britain)

Wed Jun 03, 2020 02:00

Correction: Confocal Raman microspectroscopy for skin characterization: a comparative study between human skin and pig skin

Analyst, 2020, Advance ArticleDOI: 10.1039/D0AN90060E, Correction Open Access This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Sana Tfaili, Cyril Gobinet, Gwendal Josse, Jean-François Angiboust, Michel Manfait, Olivier PiotTo cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry

Royal Society of Chemistry (Great Britain) Society for Analytical Chemistry Society of Public Analysts (Great Britain)

Wed Jun 03, 2020 02:00

Development of a lateral flow immunoassay strip for rapid detection of IgG antibody against SARS-CoV-2 virus

Analyst, 2020, Accepted ManuscriptDOI: 10.1039/D0AN00629G, PaperTian Wen, Chao Huang, Feng-Juan Shi, Xiao-Yan Zeng, Tian Lu, Shou-Nian Ding, Yongjun jiaoThe ongoing worldwide SARS-CoV-2 epidemic has clearly had a tremendous influence on public health. Molecular detection based on oral swabs was used for confirmation of SARS-CoV-2 infection. However, high false...The content of this RSS Feed (c) The Royal Society of Chemistry

Royal Society of Chemistry (Great Britain) Society for Analytical Chemistry Society of Public Analysts (Great Britain)

Wed Jun 03, 2020 02:00

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Journal of Cancer Education

Development and Validation of the Polish Version of Questionnaire for the Assessment of Psychosocial and Functional Effects of Metastatic Breast Cancer

Abstract The aim of this study is to adapt culturally and validate a questionnaire assessing experiences of metastatic breast cancer (MBC) patients in Poland. The questionnaire development was divided into three phases: bidirectional translation of the survey, testing it for acceptability and relevance, and field testing. In the field study, 320 women with MBC completed the questionnaire, 50 of them twice for retest. Basic psychometric properties of the items used in questionnaire...

Journal of Cancer Education

Wed Jun 03, 2020 03:00

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Impact of hypoxia on chemoresistance of mesothelioma mediated by the proton-coupled folate transporter, and preclinical activity of new anti-LDH-A compounds

British Journal of Cancer, Published online: 04 June 2020; doi:10.1038/s41416-020-0912-9Impact of hypoxia on chemoresistance of mesothelioma mediated by the proton-coupled folate transporter, and preclinical activity of new anti-LDH-A compounds

Resistance training and total and site-specific cancer risk: a prospective cohort study of 33,787 US men

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British Journal of Cancer, Published online: 04 June 2020; doi:10.1038/s41416-020-0921-8Resistance training and total and site-specific cancer risk: a prospective cohort study of 33,787 US men

Resistance training and total and site-specific cancer risk: a prospective cohort study of 33,787 US men

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Impact of hypoxia on chemoresistance of mesothelioma mediated by the proton-coupled folate transporter, and preclinical activity of new anti-LDH-A compounds

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Latest Results for Child's Nervous System

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Why a focus session on fetal ventriculomegaly and congenital hydrocephalus?

Abstract Introduction to the Special Focus Session on Fetal ventriculomegaly and Congenital Hydrocephalus.

Latest Results for Child's Nervous System

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Treatment of malignant peripheral nerve sheath tumors in pediatric NF1 disease

Abstract Background Malignant peripheral nerve sheath tumors (MPNSTs) are rare yet highly aggressive soft tissue sarcomas. Children with neurofibromatosis type 1 (NF1) have a 10% lifetime risk for development of MPNST. Prognosis remains poor and survival seems worse for NF1 patients. Methods This narrative review highlights current practices and pitfalls...

Latest Results for Child's Nervous System

Wed Jun 03, 2020 03:00

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Radiotherapy and Oncology

Regarding kaanders JHAM et al. '' Advances in cancer imaging require renewed radiotherapy dose and target volume concepts“

We read the great article by Kaanders JHAM et al which emphasized the concept of radiotherapy volume should be changed in the era of modern cancer image [1]. We agreed with the authors but would like to emphasize additional literatures not cited by the authors but supporting their concept in lung cancer radiotherapy.

Radiotherapy and Oncology

Wed Jun 03, 2020 03:00

Organ at risk delineation for radiation therapy clinical trials: Global Harmonization Group consensus guidelines

Clinical research in radiation therapy is conducted two-fold: through analysis of high-level evidence generated from well-conducted prospective clinical trials, or retrospective evaluation of real-world data extracted from big data repositories [1,2]. The dosimetric, toxicity, and endpoint reporting parameters from these datasets inform the development of normal tissue complication probability (NTCP) models and define organ at risk (OAR) constraints for future radiation therapy planning protocols...

Radiotherapy and Oncology

Wed Jun 03, 2020 03:00

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The Thoracic and Cardiovascular Surgeon Reports

Traditional Atriopulmonary Connection Fontan with Excellent Outcome for 32 Years

Thorac Cardiovasc Surg Rep 2020; 09: e18-e20DOI: 10.1055/s-0040-1708528Although the traditional right atrial–pulmonary artery (RA–PA) Fontan has been replaced by the total cavopulmonary connection, some RA–PA Fontan patients still have good outcome. We report a 37-year-old male who underwent traditional Fontan 32 years ago with the diagnosis of L-transposition of great arteries, subvalvular pulmonary stenosis and cardiac dextroversion. Among the recent CTA, electroconvulsive therapy, catheterization...

The Thoracic and Cardiovascular Surgeon Reports

Wed Jun 03, 2020 02:00

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Journal of the American Chemical Society: Latest Articles (ACS Publications)

[ASAP] Heterogeneous Interactions Promote Crystallization and Spontaneous Resolution of Chiral Molecules

Journal of the American Chemical SocietyDOI: 10.1021/jacs.0c02097

Journal of the American Chemical Society: Latest Articles (ACS Publications)

Wed Jun 03, 2020 07:00

[ASAP] GLRX3 Acts as a [2Fe–2S] Cluster Chaperone in the Cytosolic Iron–Sulfur Assembly Machinery Transferring [2Fe–2S] Clusters to NUBP1

Journal of the American Chemical SocietyDOI: 10.1021/jacs.0c02266

Journal of the American Chemical Society: Latest Articles (ACS Publications)

Wed Jun 03, 2020 07:00

[ASAP] Enantioselective Hydroxylation of Benzylic C(sp3)–H Bonds by an Artificial Iron Hydroxylase Based on the Biotin–Streptavidin Technology

Journal of the American Chemical SocietyDOI: 10.1021/jacs.0c02788

Journal of the American Chemical Society: Latest Articles (ACS Publications)

Wed Jun 03, 2020 07:00

[ASAP] Determining Proton-Coupled Standard Potentials and X–H Bond Dissociation Free Energies in Nonaqueous Solvents Using Open-Circuit Potential Measurements

Journal of the American Chemical SocietyDOI: 10.1021/jacs.0c01032

Journal of the American Chemical Society: Latest Articles (ACS Publications)

Wed Jun 03, 2020 07:00

[ASAP] Influence of the Spatial Distribution of Cationic Functional Groups at Nanoparticle Surfaces on Bacterial Viability and Membrane Interactions

Journal of the American Chemical SocietyDOI: 10.1021/jacs.0c02737

Journal of the American Chemical Society: Latest Articles (ACS Publications)

Wed Jun 03, 2020 07:00

[ASAP] Photolysis of Caged Inositol Pyrophosphate InsP8 Directly Modulates Intracellular Ca2+ Oscillations and Controls C2AB Domain Localization

Journal of the American Chemical SocietyDOI: 10.1021/jacs.0c01697

Journal of the American Chemical Society: Latest Articles (ACS Publications)

Wed Jun 03, 2020 07:00

[ASAP] Radical SAM Enzyme HydE Generates Adenosylated Fe(I) Intermediates En Route to the [FeFe]-Hydrogenase Catalytic H-Cluster

Journal of the American Chemical SocietyDOI: 10.1021/jacs.0c03802

Journal of the American Chemical Society: Latest Articles (ACS Publications)

Wed Jun 03, 2020 07:00

[ASAP] Understanding the Origin of One- or Two-Step Valence Tautomeric Transitions in Bis(dioxolene)-Bridged Dinuclear Cobalt Complexes

Journal of the American Chemical SocietyDOI: 10.1021/jacs.0c01073

Journal of the American Chemical Society: Latest Articles (ACS Publications)

Tue Jun 02, 2020 07:00

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[ASAP] Fast and Automated Characterization of Monoclonal Antibody Minor Variants from Cell Cultures by Combined Protein-A and Multidimensional LC/MS Methodologies

Analytical ChemistryDOI: 10.1021/acs.analchem.0c01250

[ASAP] Profiling Glucose-Stimulated and M3 Receptor-Activated Insulin Secretion Dynamics from Islets of Langerhans Using an Extended-Lifetime Fluorescence Dye

Wed Jun 03, 2020 07:00

Analytical ChemistryDOI: 10.1021/acs.analchem.0c01226

[ASAP] Highly Efficient Peptide-Based Click Chemistry for Proteomic Profiling of Nascent Proteins

Wed Jun 03, 2020 07:00

Analytical ChemistryDOI: 10.1021/acs.analchem.0c00594

[ASAP] Scanning Electrochemical Photometric Sensors for Label-Free Single-Cell Imaging and Quantitative Absorption Analysis

Wed Jun 03, 2020 07:00

Analytical ChemistryDOI: 10.1021/acs.analchem.0c01118

[ASAP] Rapid and Targeted Photoactivation of Ca2+ Channels Mediated by Squaraine To Regulate Intracellular and Intercellular Signaling Processes

Wed Jun 03, 2020 07:00

Analytical ChemistryDOI: 10.1021/acs.analchem.0c01243

[ASAP] Quantitative Analysis of the Positional Distribution of Hydroxyproline in Collagenous Gly-Xaa-Yaa Sequences by LC–MS with Partial Acid Hydrolysis and Precolumn Derivatization

Wed Jun 03, 2020 07:00

Analytical ChemistryDOI: 10.1021/acs.analchem.0c01098

[ASAP] Compartmentalized Arrays of Matrix Droplets for Quantitative Mass Spectrometry Imaging of Adsorbed Peptides

Wed Jun 03, 2020 07:00

Analytical ChemistryDOI: 10.1021/acs.analchem.9b05316