Related Articles Association of Clinicopathological Features With Outcome in Chondrosarcomas of the Head and Neck. Otolaryngol Head Neck Surg. 2020 Sep 15;:194599820957271 Authors: Asioli S, Ruengwanichayakun P, Zoli M, Guaraldi F, Sollini G, Greco P, Facco C, Gibertoni D, Jiménez BV, Benini S, Turri-Zanoni M, Pasquini E, Mazzatenta D, Foschini MP, Righi A Abstract OBJECTIVE: The aim of this study is to assess the association between clinical...
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Related Articles Communicative Participation and Quality of Life in Pretreatment Oral and Oropharyngeal Head and Neck Cancer. Otolaryngol Head Neck Surg. 2020 Sep 15;:194599820950718 Authors: Sauder C, Kapsner-Smith M, Baylor C, Yorkston K, Futran N, Eadie T Abstract OBJECTIVE: To determine how communicative participation is affected in patients with oral and oropharyngeal head and neck cancers (HNCs) pretreatment and whether communication...
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Related Articles Airborne Aerosolized Mouse Cytomegalovirus From Common Otolaryngology Procedures: Implications for COVID-19 Infection. Otolaryngol Head Neck Surg. 2020 Sep 15;:194599820957966 Authors: Sayahi T, Nielson C, Yu Y, Neuberger K, Seipp M, Firpo MA, Kelly K, Park AH Abstract OBJECTIVES: To determine whether common otolaryngology procedures generate viable aerosolized virus through a murine cytomegalovirus (mCMV) model for infection....
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Related Articles Risk Factors for Post-acute care Following Free Flap Reconstruction of the Oral Cavity. Otolaryngol Head Neck Surg. 2020 Sep 15;:194599820955175 Authors: Lepse J, Sykes KJ, Kakarala K Abstract OBJECTIVE: Identify previously unreported factors that predict the need for post-acute care after free flap reconstruction of the oral cavity. STUDY DESIGN: Retrospective cohort study. SETTING: Single academic...
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Related Articles Timing the First Pediatric Tracheostomy Tube Change: A Randomized Controlled Trial. Otolaryngol Head Neck Surg. 2020 Sep 15;:194599820954137 Authors: Chorney SR, Patel RC, Boyd AE, Stow J, Schmitt MM, Lipman D, Dailey JF, Nhan C, Giordano T, Sobol SE Abstract OBJECTIVE: The first pediatric tracheostomy tube change often occurs within 7 days after placement; however, the optimal timing is not known. The primary objective...
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Related Articles A Qualitative Study Exploring Patient, Family Carer and Healthcare Professionals' Direct Experiences and Barriers to Providing and Integrating Palliative Care for Advanced Head and Neck Cancer. J Palliat Care. 2020 Sep 15;:825859720957817 Authors: Mayland CR, Doughty HC, Rogers SN, Gola A, Mason S, Hubbert C, Macareavy D, Jack BA Abstract OBJECTIVES: To report on direct experiences from advanced head and neck cancer patients,...
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Related Articles Sentinel lymph node mapping using ICG fluorescence and cone beam CT - a feasibility study in a rabbit model of oral cancer. BMC Med Imaging. 2020 Sep 14;20(1):106 Authors: Muhanna N, Chan HHL, Douglas CM, Daly MJ, Jaidka A, Eu D, Bernstein J, Townson JL, Irish JC Abstract BACKGROUND: Current sentinel lymph node biopsy (SLNB) techniques, including use of radioisotopes, have disadvantages including the use of a radioactive...
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Related Articles From tobacco smoking to cancer mutational signature: a mediation analysis strategy to explore the role of epigenetic changes. BMC Cancer. 2020 Sep 14;20(1):880 Authors: Chen Z, Wen W, Cai Q, Long J, Wang Y, Lin W, Shu XO, Zheng W, Guo X Abstract BACKGROUND: Tobacco smoking is associated with a unique mutational signature in the human cancer genome. It is unclear whether tobacco smoking-altered DNA methylations and gene...
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Related Articles Anti-proliferative activity of A. Oxyphylla and its bioactive constituent nootkatone in colorectal cancer cells. BMC Cancer. 2020 Sep 14;20(1):881 Authors: Yoo E, Lee J, Lertpatipanpong P, Ryu J, Kim CT, Park EY, Baek SJ Abstract BACKGROUND: A. oxyphylla extract is known to possess a wide range of pharmacological activites. However, the molecular mechanism of A. oxyphylla and its bioactive compound nootkatone in colorectal...
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Related Articles Pediatric rigid bronchoscopy and foreign body removal during the COVID-19 pandemic: case report. J Otolaryngol Head Neck Surg. 2020 Sep 14;49(1):66 Authors: Leitao DJ, Jones JLP Abstract We present the case of an eight year old boy who presented with foreign body aspiration during the COVID-19 pandemic. The patient was taken the operating room for rigid bronchoscopy and foreign body removal. The details of the operation,...
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Related Articles Functional Magnetic Resonance Imaging during Visual Perception Tasks in Adolescents Born Prematurely. J Int Neuropsychol Soc. 2020 Sep 15;:1-12 Authors: Lind A, Haataja L, Laasonen M, Saunavaara V, Railo H, Lehtonen T, Vorobyev V, Uusitalo K, Lahti K, Parkkola R, PIPARI Study Group Abstract OBJECTIVES: Impairments in visual perception are among the most common developmental difficulties related to being born prematurely,...
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Related Articles Robotic Skull Base Surgery. Otolaryngol Clin North Am. 2020 Sep 11;: Authors: Heuermann M, Michael AP, Crosby DL Abstract Robotic surgery has become more common in otolaryngologic surgery since the introduction of the da Vinci robotic system, but has played a limited role in anterior and central skull base surgery, largely because of technical limitations of existing robots. Current robotic technology has been used in creative...
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Related Articles Correlation Between Presbylarynx and Laryngeal EMG. J Voice. 2020 Sep 11;: Authors: Park J, Alnouri G, Eichorn D, Sataloff RT Abstract BACKGROUND: The normal aging process affects many human functions profoundly. The voice is no exception, and some aging effects on the voice are obvious including vocal fold atrophy, bowing, stiffness, more prominent vocal fold processes, and glottic insufficiency. The study's primary aim...
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Related Articles The ABS brachytherapy schools. Brachytherapy. 2020 Sep 11;: Authors: Erickson B, Crook J, Vicini F, Arthur D, Ouhib Z, Thomadsen B, Bice W, Butler WM, Petereit DG, Viswanathan AN Abstract The American Brachytherapy Society brachytherapy schools have been pivotal in teaching and evolving the art of brachytherapy over the past decades. Founded in 1995, the schools have consistently provided content for the major disease sites...
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Related Articles Multi-omic studies on missense PLG variants in families with otitis media. Sci Rep. 2020 Sep 14;10(1):15035 Authors: Bootpetch TC, Hafrén L, Elling CL, Baschal EE, Manichaikul AW, Pine HS, Szeremeta W, Scholes MA, Cass SP, Larson ED, Chan KH, Ishaq R, Prager JD, Shaikh RS, Gubbels SP, Yousaf A, University of Washington Center for Mendelian Genomics (UW-CMG), Wine TM, Bamshad MJ, Yoon PJ, Jenkins HA, Nickerson DA, Streubel SO, Friedman NR,...
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Related Articles Integrative genomic analysis of salivary duct carcinoma. Sci Rep. 2020 Sep 14;10(1):14995 Authors: Kim Y, Song S, Lee M, Swatloski T, Kang JH, Ko YH, Park WY, Jeong HS, Park K Abstract Salivary duct carcinoma (SDC) is one of the most aggressive subtypes of salivary gland cancers. Conventional chemotherapy and/or radiation have shown only limited clinical efficacy in the treatment of recurrent or metastatic SDC. Currently,...
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Related Articles Breath methane to hydrogen ratio as a surrogate marker of intestinal dysbiosis in head and neck cancer. Sci Rep. 2020 Sep 14;10(1):15010 Authors: Dharmawardana N, Goddard T, Woods C, Watson DI, Butler R, Ooi EH, Yazbeck R Abstract Exhaled breath compounds can non-invasively detect head and neck squamous cell carcinoma (HNSCC). Here we investigated exhaled compounds related to intestinal bacterial carbohydrate fermentation....
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Related Articles Establishment of patient-derived cancer organoids for drug-screening applications. Nat Protoc. 2020 Sep 14;: Authors: Driehuis E, Kretzschmar K, Clevers H Abstract Adult stem cell-based organoid technology is a versatile tool for the generation and long-term maintenance of near-native 3D epithelial tissues in vitro. The generation of cancer organoids from primary patient material enables a range of therapeutic agents to...
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Related Articles Combination therapy with B7H3-redirected bispecific antibody and Sorafenib elicits enhanced synergistic antitumor efficacy. Theranostics. 2020;10(23):10498-10512 Authors: Huang C, Li H, Feng Y, Li X, Zhang Z, Jiang C, Wang J, Yang C, Fu Y, Mu M, Zhao S, Wang Z, Kuang Y, Hou H, Wang Y, Guo W, Xu J, Yang H, Zhou L, Tong A, Guo G Abstract Rationale: Current traditional treatment options are frequently ineffective to fight against...
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Related Articles EREG-driven oncogenesis of Head and Neck Squamous Cell Carcinoma exhibits higher sensitivity to Erlotinib therapy. Theranostics. 2020;10(23):10589-10605 Authors: Liu S, Wang Y, Han Y, Xia W, Zhang L, Xu S, Ju H, Zhang X, Ren G, Liu L, Ye W, Zhang Z, Hu J Abstract Rationale: The oncogenesis of head and neck squamous cell carcinoma (HNSCC) is believed to result from oncogene activation and tumor suppressor inactivation. Here,...
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Related Articles Genome and transcriptome profiling of FBXW family in human prostate cancer. Am J Clin Exp Urol. 2020;8(4):116-128 Authors: Lan R, Jin B, Liu YZ, Zhang K, Niu T, You Z Abstract F-box and WD repeat domain containing (FBXW) family of E3 ligases has 10 members that ubiquitinate substrate proteins for proteasome-mediated degradation. Publicly archived datasets from The Cancer Genome Atlas (TCGA), Prostate Cancer Transcriptome Atlas...
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Related Articles Critical Care Guidance for Tracheostomy Care During the COVID-19 Pandemic: A Global, Multidisciplinary Approach. Am J Crit Care. 2020 Sep 15;:e1-e12 Authors: Pandian V, Morris LL, Brodsky MB, Lynch J, Walsh B, Rushton C, Phillips J, Rahman A, DeRose T, Lambe L, Lami L, Man Wu SP, Garza FP, Maiani S, Zavalis A, Okusanya KA, Palmieri PA, McGrath BA, Pelosi P, Sole ML, Davidson P, Brenner MJ Abstract PURPOSE: Critical care...
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Related Articles [Tumor microenvironment in salivary gland carcinomas: Consequences for new therapeutic concepts]. HNO. 2020 Sep 14;: Authors: Meyer MF, Arolt C, Kansy BA, Doescher J, Quaas A, Beutner D, Lang S, Klußmann JP Abstract INTRODUCTION: Salivary gland carcinomas (SGCs) are rare tumors which represent a challenge for diagnosis and therapy due to their histological diversity and the different disease courses depending on the respective...
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Related Articles [Functional outcome after transmandibular resection and primary chemoradiation in advanced oropharyngeal squamous cell carcinoma]. HNO. 2020 Sep 14;: Authors: Knopf A, Mansour N, Hofauer B, Johnson F, Bier H, Wakonig F, Teutsch S Abstract OBJECTIVE: The aim of this study was to assess the functional outcome after transmandibular resection and reconstruction via a radial forearm flap (TMR+RFF) compared to primary chemoradiotherapy...
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Related Articles [Plastic reconstructive surgery in patients with oropharyngeal tumors]. HNO. 2020 Sep 14;: Authors: Remmert S, Hasenberg S Abstract Oropharyngeal tumors can cause severe dysfunctions, which are often worsened by surgical and/or radiotherapy. The severity and type of dysfunction depends on the extent and localization of the resection. In general, entire organ resections lead to greater impairment than partial resections,...
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Related Articles Association between temporal muscle thickness and clinical outcomes in patients with newly diagnosed glioblastoma. J Cancer Res Clin Oncol. 2020 Sep 14;: Authors: An G, Ahn S, Park JS, Jeun SS, Hong YK Abstract PURPOSE: Temporal muscle thickness (TMT) has been suggested as a novel biomarker that can represent sarcopenia in head and neck malignancies. This study investigated the association of TMT with clinical outcomes...
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Related Articles The incidence of newly diagnosed secondary cancer; sub-analysis the prospective study of the second-look procedure for transoral surgery in patients with T1 and T2 head and neck cancer. Int J Clin Oncol. 2020 Sep 14;: Authors: Nishimura G, Sano D, Arai Y, Hatano T, Takahashi H, Kitani Y, Takada K, Wada T, Oridate N Abstract BACKGROUND: Our prospective study of patients with early T-stage head and neck cancer indicated a...
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Related Articles Transoral robotic parapharyngeal approach to the submandibular space. Head Neck. 2020 Sep 15;: Authors: Floros P, Sorrentino M, Magnuson JS Abstract The aim of the study was to demonstrate a novel transoral parapharyngeal approach to the submandibular space. The method used was the clinical case of a patient presenting with an anteriorly based tumor in the left submandibular space. The video shows the transoral robotic...
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Population-based analysis on the effect of nodal and distant metastases in sinonasal adenocarcinoma.
Related Articles Population-based analysis on the effect of nodal and distant metastases in sinonasal adenocarcinoma. Head Neck. 2020 Sep 15;: Authors: Chweya CM, Low CM, Van Gompel JJ, Van Abel KM, Stokken JK, Choby G Abstract BACKGROUND: Minimal information has been reported on the effect of distant and nodal metastases at the time of diagnosis on survival in patients with sinonasal adenocarcinoma (SNAC). METHODS: The Surveillance,...
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Related Articles Effectiveness and safety of herbal medicine for cancer-related fatigue in lung cancer survivors: A systematic review and meta-analysis. Phytother Res. 2020 Sep 14;: Authors: Kwon CY, Lee B, Kong M, Lee SH, Jung HJ, Kim KI, Lee BJ Abstract Approximately half of lung cancer patients (LCP) receiving chemotherapy are experiencing cancer-related fatigue (CRF). In East Asia, herbal medicines (HMs) have been used as tonics due...
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Related Articles A population-based case-control study of the association between cervical spondylosis and tinnitus. Int J Audiol. 2020 Sep 15;:1-5 Authors: Cheng YF, Xirasagar S, Yang TH, Wu CS, Kuo NW, Lin HC Abstract OBJECTIVE: This population-based study aimed to study the association between tinnitus and cervical spondylosis. DESIGN: A case-control study. STUDY SAMPLE: We retrieved data from the Taiwan Longitudinal...
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Related Articles The characteristics of vHIT gain and PR score in peripheral vestibular disorders. Acta Otolaryngol. 2020 Sep 15;:1-7 Authors: Du Y, Ren L, Liu X, Guo W, Wu Z, Yang S Abstract BACKGROUND: Clinical application of vHIT is limited due to a lack of interpretation of vHIT gain and saccades. OBJECTIVES: This research focuses on comparing common vertigo diseases on vHIT gain and saccade divergence(PR score). ...
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Related Articles Synchronous thoracic and head-and-neck malignancies-double trouble-challenges, pitfalls, and lessons learnt. J Cancer Res Ther. 2020 Jul-Sep;16(4):946-949 Authors: Sood KS, Himthani M, Tanwar A, Perumal SL Abstract Synchronous malignancies arising from head and neck and thorax are rare presentation, and only few cases are reported in the scientific literature. We report three cases of double primary malignancies treated...
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Related Articles Unraveling most abundant mutational signatures in head and neck cancer. Int J Cancer. 2020 Sep 15;: Authors: Plath M, Gass J, Hlevnjak M, Li Q, Feng B, Hostench XP, Bieg M, Schroeder L, Holzinger D, Zapatka M, Freier K, Weichert W, Hess J, Zaoui K Abstract Genomic alterations are a driving force in the multistep process of head and neck cancer (HNC) and result from the interaction of exogenous environmental exposures and...
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Related Articles In Response to Method of Lateral Osteotomy to Reduce Eyelid Ecchymosis After Rhinoplasty: A Meta-analysis. Laryngoscope. 2020 Sep 15;: Authors: Hwang SH PMID: 32930396 [PubMed - as supplied by publisher]
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Related Articles CD8+ T Cell Infiltration Predicts Chemoradiosensitivity in Nasopharyngeal or Oropharyngeal Cancer. Laryngoscope. 2020 Sep 15;: Authors: Kawaguchi T, Ono T, Sato F, Kawahara A, Kakuma T, Akiba J, Sato K, Chitose SI, Umeno H Abstract OBJECTIVES: Limited information exists regarding the associations between pre-existing immune parameters in the tumor immune microenvironment (TIM) and either chemoradiosensitivity or prognosis...
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Related Articles Phase 2 of coronavirus disease (COVID-19) and head and neck cancer: An action plan. Oral Dis. 2020 Jul 29;: Authors: De Felice F, Valentini V, de Vincentiis M, Catalano C, Musio D, Mezi S, Messineo D, Di Gioia CRT, Tenore G, Priore P, Ralli M, Vullo F, Botticelli A, Brauner E, Giovannetti F, Greco A, Romeo U, Marchetti P, Della Rocca C, Polimeni A, Tombolini V PMID: 32930434 [PubMed - as supplied by publisher]
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Related Articles Machine Learning-Based MRI Texture Analysis to Predict the Histologic Grade of Oral Squamous Cell Carcinoma. AJR Am J Roentgenol. 2020 Sep 15;:1-7 Authors: Ren J, Qi M, Yuan Y, Duan S, Tao X Abstract OBJECTIVE. This study aimed to explore the performance of machine learning (ML)-based MRI texture analysis in discriminating between well-differentiated (WD) oral squamous cell carcinoma (OSCC) and moderately or poorly differentiated...
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Related Articles Core outcome sets in cancer and their approaches to identifying and selecting patient-reported outcome measures: a systematic review. J Patient Rep Outcomes. 2020 Sep 15;4(1):77 Authors: Ramsey I, Eckert M, Hutchinson AD, Marker J, Corsini N Abstract OBJECTIVES: Issues arising from a lack of outcome standardisation in health research may be addressed by the use of core outcome sets (COS), which represent agreed-upon recommendations...
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Related Articles Association between postoperative complications and long-term oncologic outcomes following total laryngectomy: 10-year experience at MD Anderson Cancer Center. Cancer. 2020 Sep 15;: Authors: Boukovalas S, Goepfert RP, Smith JM, Mecham E, Liu J, Zafereo ME, Chang EI, Hessel AC, Hanasono MM, Gross ND, Yu P, Lewin JS, Lewis CM, Diaz EM, Weber RS, Myers JN, Offodile AC Abstract BACKGROUND: Postoperative complications are an...
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Related Articles Alveolar Soft-Part Sarcoma in Olfactory Cleft: A Case Report and Clinicopathological Review. Ear Nose Throat J. 2020 Sep 15;:145561320955134 Authors: Alromaih S, Alqaryan S, Alabood S, Alabaishi S, Ajlan A, Alsuhaibani A, Sumaily I, Alsolami A Abstract Sinonasal alveolar soft-part sarcoma (ASPS) is a rare malignant disease that comprises 0.4% to 1.2% of all soft-tissue sarcomas. Alveolar soft-part sarcoma is usually difficult...
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Related Articles Ulcerative Warthin Tumor: A Case Report and Review of the Literature. Ear Nose Throat J. 2020 Sep 15;:145561320957574 Authors: Hung CJ, Kang BH, Wang JS, Lin YS Abstract Warthin tumor with ulceration of the surrounding skin is extremely rare, making it difficult to differentiate from parotid cancer in the clinical setting. We report a 65-year-old man with a Warthin tumor in the right parotid gland that had ulceration of...
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Related Articles A pro-tumorigenic secretory pathway activated by p53 deficiency in lung adenocarcinoma. J Clin Invest. 2020 Sep 15;: Authors: Tan X, Shi L, Banerjee P, Liu X, Guo HF, Yu J, Bota-Rabassedas N, Rodriguez BL, Gibbons DL, Russell WK, Creighton CJ, Kurie JM Abstract Therapeutic strategies designed to target TP53-deficient cancer cells remain elusive. Here, we showed that TP53 loss initiated a pharmacologically actionable secretory...
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Related Articles Analysis of chemotherapy effect on the second primary malignancy for head and neck cancer patients by a nomogram based on SEER database. Cancer Med. 2020 Sep 15;: Authors: Li X, Guo K, Feng Y, Guo Y Abstract Second primary malignancy (SPM) ranks the second leading cause of death in patients with head and neck cancer (HNC), while studies exploring the risk factors for SPM are limited. To clarify this, we investigated the...
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Related Articles Balloon Eustachian tuboplasty in a professional Navy SEAL diver: case report. Undersea Hyperb Med. 2020 Third Quarter;47(3):467-470 Authors: Tsur N, Bar R, Hilly O, Handzel O Abstract Middle ear barotrauma due to dilatory Eustachian tube dysfunction (ETD) is probably the most common medical disorder related to diving. Moreover, ETD makes divers prone to other diving-related accidents, including inner ear barotrauma and...
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Related Articles Clinicopathologic, immunohistochemical, molecular cytogenetic profile with treatment and outcomes of 34 cases of Ewing sarcoma with epithelial differentiation, including 6 cases with "Adamantinoma-like" features, diagnosed at a single institution, India. Ann Diagn Pathol. 2020 Sep 09;49:151625 Authors: Rekhi B, Shetty O, Vora T, Gulia A, Bajpai J, Laskar S Abstract To analyze clinicopathological features, including treatment...
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Related Articles Embryonal mastoid rhabdomyosarcoma in a three years old child: A case report. Int J Surg Case Rep. 2020 Sep 03;75:108-111 Authors: Beghdad M, Mkhatri A, Berrada O, Abada R, Mahtar M Abstract INTRODUCTION: Rhabdomyosarcoma is the most common malignant soft tissue tumor in the pediatric age, especially in the head and neck region; in the orbit and the nasopharynx. The middle ear is a very rare site for this neoplasm as it...
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Related Articles Antihypertensive properties of a traditional Chinese medicine GAO-ZI-YAO in elderly spontaneous hypertensive rats. Biomed Pharmacother. 2020 Sep 12;131:110739 Authors: Dai B, Wang ZZ, Zhang H, Han MX, Zhang GX, Chen JW Abstract AIM: The present study aims to investigate the antihypertensive effect and the underlying mechanism of GAO-ZI-YAO, one of the traditional Chinese medicines, in elderly spontaneous hypertensive rats...
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Related Articles Increasing prevalence of HPV in oropharyngeal carcinoma suggests adaptation of p16 screening in Southeast Asia. J Clin Virol. 2020 Sep 09;132:104637 Authors: Argirion I, Zarins KR, McHugh J, Cantley RL, Teeramatwanich W, Laohasiriwong S, Kasemsiri P, Naruikon J, Srimanta P, Chinn SB, Vatanasapt P, Rozek LS Abstract BACKGROUND: Human papillomavirus (HPV) is etiologically linked to increasing oropharyngeal squamous cell carcinoma...
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Related Articles Impact of notch signaling on the prognosis of patients with head and neck squamous cell carcinoma. Oral Oncol. 2020 Sep 12;110:105003 Authors: Grilli G, Hermida-Prado F, Álvarez-Fernández M, Allonca E, Álvarez-González M, Astudillo A, Moreno-Bueno G, Cano A, García-Pedrero JM, Rodrigo JP Abstract OBJECTIVES: The function of NOTCH signaling (oncogenic or oncosuppressive) remains controversial in head and neck squamous cell...
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Related Articles Pretreatment age and serum lactate dehydrogenase as predictors of synchronous second primary cancer in patients with nasopharyngeal carcinoma. Oral Oncol. 2020 Sep 12;110:104990 Authors: Yeh CF, Ho CY, Chin YC, Shu CH, Chao YT, Lan MY Abstract OBJECTIVES: Nasopharyngeal carcinoma (NPC) is a common cancer and is treated primarily by chemotherapy and radiotherapy. However, NPC with synchronous second primary cancer (SSPC)...
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Related Articles Induction chemotherapy in nonlaryngeal human papilloma virus-negative high-risk head and neck cancer: a real-world experience. Anticancer Drugs. 2020 Sep 10;: Authors: Mezi S, Pomati G, Botticelli A, Roberto M, Cerbelli B, Cirillo A, Di Gioia C, Corsi A, Vullo F, De Vincentiis M, Polimeni A, Tombolini V, Valentini V, Marchetti P Abstract OBJECTIVE: The role of induction chemotherapy in the multidisciplinary treatment of...
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Abstract Aspirin is considered a potential confound for functional magnetic resonance imaging (fMRI) studies. This is because aspirin affects the synthesis of prostaglandin, a vasoactive mediator centrally involved in neurovascular coupling, a process underlying blood oxygenated level dependent (BOLD) responses. Aspirin‐induced changes in BOLD signal are a potential confound for fMRI studies of at‐risk individuals or patients (e.g. with cardiovascular conditions or stroke) who receive low‐dose aspirin...
Wed Sep 16, 2020 20:08
Related Articles The effect of a stress and anxiety coping program on objective structured clinical examination performance among nursing students in shiraz, Iran. BMC Med Educ. 2020 Sep 14;20(1):301 Authors: Mojarrab S, Bazrafkan L, Jaberi A Abstract BACKGROUND: Evaluation of the competence and practical skills of nursing students, using the objective structured clinical examination (OSCE), is an integral part of the nursing education program....
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Related Articles Adaptive tutorials versus web-based resources in radiology: a mixed methods analysis in junior doctors of efficacy and engagement. BMC Med Educ. 2020 Sep 14;20(1):303 Authors: Wade SWT, Moscova M, Tedla N, Moses DA, Young N, Kyaw M, Velan GM Abstract BACKGROUND: Radiology education is limited in undergraduate Medicine programs. Junior doctors might not have the necessary background to effectively order and interpret diagnostic...
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Related Articles Knowledge of CT exposure parameters among Norwegian student radiographers. BMC Med Educ. 2020 Sep 14;20(1):302 Authors: Kada S Abstract BACKGROUND: Improvements in the competency levels of student radiographers in computed tomography examinations (CT) are important due to the increasing number of these examinations being undertaken in imaging departments. The present study assesses the knowledge of student radiographers regarding...
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Related Articles A commentary on "A simple four-factor preoperative recipient scoring model for prediction of 90-day mortality after adult liver Transplantation: A retrospective cohort study" (Int. J. Surg. 2020; 81, 26-31). Int J Surg. 2020 Sep 12;: Authors: Li CW, Cheng Y, Xue FS, Yuan YJ PMID: 32931974 [PubMed - as supplied by publisher]
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Related Articles Implementation of the WHO Trauma Care Checklist: A Qualitative Analysis of Facilitators and Barriers to Use. Int J Surg. 2020 Sep 12;: Authors: Wild H, Mock C, Lim A Abstract BACKGROUND: The World Health Organization (WHO) Trauma Care Checklist (TCC) has been documented to improve care of the injured. Factors that promote TCC use have not been well evaluated. We sought to identify barriers and facilitators affecting TCC...
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Related Articles Primary Tumor Removal Improves the prognosis In Patients with Stage IV Breast Cancer: A Population-Based Study (Cohort Study). Int J Surg. 2020 Sep 12;: Authors: Yao N, Li W, Liu T, Siyin ST, Chen X, Wang W, Duan N, Chen YT, Qu J Abstract Adjuvant therapy including chemotherapy, hormonal therapy, and radiotherapy were often used as a common stereotypy for female stage IV breast cancer rather than surgery. This study aimed...
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Related Articles Clinical efficacy of surgical versus conservative treatment for multiple rib fractures: a meta-analysis of randomized controlled trials. Int J Surg. 2020 Sep 12;: Authors: Long R, Tian J, Wu S, Li Y, Yang X, Fei J Abstract BACKGROUND: There are still controversies between surgical venous or conservative treatment for multiple rib fractures (MRFs). No consensus has been reached concerning the indications and timing of surgery....
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Related Articles Outcomes of a new slowly resorbable biosynthetic mesh (Phasix™) in potentially contaminated incisional hernias: a prospective, multi-center, single-arm trial. Int J Surg. 2020 Sep 12;: Authors: van Rooijen MM, Jairam AP, Tollens T, Jørgensen LN, de Vries Reilingh TS, Piessen G, Köckerling F, Miserez M, Windsor AC, Berrevoet F, Fortelny RH, Dousset B, Woeste G, van Westreenen HL, Gossetti F, Lange JF, Tetteroo GW, Koch A, Kroese LF, Jeekel...
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Related Articles Mechanisms of recurrent laryngeal nerve injury near the nerve entry point during thyroid surgery: a retrospective cohort study. Int J Surg. 2020 Sep 12;: Authors: Liu N, Chen B, Li L, Zeng Q, Sheng L, Zhang B, Liang W, Lv B Abstract BACKGROUND: The use of intraoperative neuromonitoring (IONM) for visual identification of recurrent laryngeal nerve (RLN) has decreased the rates of RLN injury (RLNI) during thyroid surgery....
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Related Articles A single-centre observational cohort study to evaluate volume and severity of emergency general surgery admissions during the COVID-19 pandemic: is there a "lockdown" effect? Int J Surg. 2020 Sep 12;: Authors: McLean RC, Young J, Musbahi A, Lee JX, Hidayat H, Abdalla N, Chowdhury S, Baker EA, Etherson KJ Abstract INTRODUCTION: The COVID-19 pandemic has led to changes in NHS surgical service provision, including reduced...
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Background Atypia of undetermined significance (AUS) is a category of the Milan System for Reporting Salivary Gland Cytopathology that refers to salivary gland fine‐needle aspiration (FNA) specimens that cannot be definitively diagnosed as neoplastic or nonneoplastic. Methods The AUS FNA samples were selected from a large academic institution from 2008 through 2018. The AUS cases were divided into 6 subgroups. The risk of malignancy (ROM), risk of neoplasm (RON), and clinical outcomes for...
Wed Sep 16, 2020 20:42
Background Undifferentiated carcinoma (UC) is a rare, aggressive subtype of endometrial carcinoma. Dedifferentiated carcinomas (DCs) are UCs associated with a component of well differentiated endometrioid carcinoma. The authors sought to describe the morphologic features of UCs and DCs in cytologic specimens. Methods Cytologic specimens from 23 women (aged 46‐86 years; median age, 59 years) were reviewed, including cervicovaginal specimens (n = 7), peritoneal washings (n = 5), touch preparations...
Wed Sep 16, 2020 20:45
Related Articles Cochlear implant in a subject affected by the Chudley-McCullough Syndrome. Cochlear Implants Int. 2019 07;20(4):217-221 Authors: Forli F, Fiacchini G, Bruschini L, Caniglia M, Berrettini S Abstract Objectives: The Chudley-McCullough Syndrome (CMS) is a rare autosomal-recessively inherited disorder caused by mutations in the GPSM2 gene, characterised by deafness and brain anomalies. The purpose of this paper is to report about...
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Related Articles Contemporary clinicopathological characteristics of pT0 prostate cancer at radical prostatectomy: A population-based study. Urol Oncol. 2019 10;37(10):696-701 Authors: Knipper S, Tilki D, Mazzone E, Mistretta FA, Palumbo C, Pecoraro A, Tian Z, Briganti A, Saad F, Graefen M, Karakiewicz PI Abstract BACKGROUND: The incidence of pT0 prostate cancer (CaP) at radical prostatectomy (RP) is extremely rare. We performed the first population-based...
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Related Articles Clinicopathological and survival analysis of clinically advanced papillary and chromophobe renal cell carcinoma. Urol Oncol. 2019 10;37(10):727-734 Authors: Kaldany A, Paulucci DJ, Kannappan M, Beksac AT, Anastos H, Okhawere K, Sfakianos JP, Badani KK Abstract INTRODUCTION: Clinically, the papillary (pRCC) and chromophobe (chRCC) histologic subtypes of renal cell carcinoma (RCC) are viewed as more indolent compared to the more-common...
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Related Articles Routine RNA sequencing of formalin-fixed paraffin-embedded specimens in neuropathology diagnostics identifies diagnostically and therapeutically relevant gene fusions. Acta Neuropathol. 2019 11;138(5):827-835 Authors: Stichel D, Schrimpf D, Casalini B, Meyer J, Wefers AK, Sievers P, Korshunov A, Koelsche C, Reuss DE, Reinhardt A, Ebrahimi A, Fernández-Klett F, Kessler T, Sturm D, Ecker J, Milde T, Herold-Mende C, Witt O, Pfister SM, Wick W,...
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Related Articles Tumour flare reaction in cancer treatments: a comprehensive literature review. Anticancer Drugs. 2019 10;30(9):953-958 Authors: Taleb B A Abstract In the past decade, tumour flare reaction (TFR) was considered as a new side effect associated with immunomodulatory agents (IMiDs) and as a condition of chronic lymphocytic leukaemia (CLL). However, this phenomenon is also observed with immune checkpoint inhibitors in solid tumours....
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Related Articles Systemic treatment of malignant gastrointestinal neuroectodermal tumour after childhood neuroblastoma: chemotherapy in malignant gastrointestinal neuroectodermal tumour. Anticancer Drugs. 2019 10;30(9):959-963 Authors: Ottaviano M, Maddalena C, D'Armiento M, Lauria R, D'Alessandro V, Tortora M, Matano E, Di Lauro V, Mucci B, Ferraro G, De Placido S, Giuliano M, Palmieri G Abstract Malignant gastrointestinal neuroectodermal...
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Related Articles Circumventing autophagy inhibition. Cell Cycle. 2019 Dec;18(24):3421-3431 Authors: Towers CG, Thorburn A Abstract Autophagy is cellular recycling process that plays a complex role in cancer. Pre-clinical studies indicating a pro-tumorigenic role of autophagy have led to the launch of dozens of clinical trials combining autophagy inhibition with other standard of care therapies in different tumor types. A recent publication...
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Related Articles Rare Germline GLMN Variants Identified from Blue Rubber Bleb Nevus Syndrome Might Impact mTOR Signaling. Comb Chem High Throughput Screen. 2019;22(10):675-682 Authors: Yin J, Qin Z, Wu K, Zhu Y, Hu L, Kong X Abstract BACKGROUND AND OBJECTIVE: Blue rubber bleb nevus syndrome (BRBN) or Bean syndrome is a rare Venous Malformation (VM)-associated disorder, which mostly affects the skin and gastrointestinal tract in early childhood....
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Related Articles CT and MRI Findings of Glomangiopericytoma in the Head and Neck: Case Series Study and Systematic Review. AJNR Am J Neuroradiol. 2020 01;41(1):155-159 Authors: Suh CH, Lee JH, Lee MK, Cho SJ, Chung SR, Choi YJ, Baek JH Abstract Glomangiopericytoma is a rare sinonasal mesenchymal tumor of borderline or low malignant potential. We reviewed the CT and MR imaging findings of head and neck glomangiopericytoma via a retrospective...
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Related Articles How should we diagnose and treat blastic plasmacytoid dendritic cell neoplasm patients? Blood Adv. 2019 12 23;3(24):4238-4251 Authors: Garnache-Ottou F, Vidal C, Biichlé S, Renosi F, Poret E, Pagadoy M, Desmarets M, Roggy A, Seilles E, Soret L, Schillinger F, Puyraimond S, Petrella T, Preudhomme C, Roumier C, MacIntyre EA, Harrivel V, Desbrosses Y, Gruson B, Geneviève F, Thepot S, Drebit Y, Leguay T, Gros FX, Lechevalier N, Saussoy P, Salaun...
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Related Articles Curative-intent pancreas resection for pancreatic metastases: surgical and oncological results. Clin Exp Metastasis. 2020 04;37(2):313-324 Authors: Chikhladze S, Lederer AK, Kühlbrey CM, Hipp J, Sick O, Fichtner-Feigl S, Wittel UA Abstract BACKGROUND: Pancreatic metastasis is a rare cause for pancreas surgery and often a sign of advanced disease no chance of curative-intent treatment. However, surgery for metastasis might...
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Related Articles Melanoma of unknown primary in the pancreas: should it be considered primary? BMC Surg. 2020 Apr 16;20(1):76 Authors: Jin Y, Ran C, Li F, Cheng N Abstract BACKGROUND: Malignant melanoma is characterized as highly malignant due to its rapid growth and early metastasis. Metastatic melanoma from occult primary is rare. Melanoma of unknown primary in pancreas are even rear. But it is a biologically ill-defined and clinically understudied...
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Related Articles Overcoming Wnt-β-catenin dependent anticancer therapy resistance in leukaemia stem cells. Nat Cell Biol. 2020 06;22(6):689-700 Authors: Perry JM, Tao F, Roy A, Lin T, He XC, Chen S, Lu X, Nemechek J, Ruan L, Yu X, Dukes D, Moran A, Pace J, Schroeder K, Zhao M, Venkatraman A, Qian P, Li Z, Hembree M, Paulson A, He Z, Xu D, Tran TH, Deshmukh P, Nguyen CT, Kasi RM, Ryan R, Broward M, Ding S, Guest E, August K, Gamis AS, Godwin A, Sittampalam GS,...
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Related Articles Primary tumor standardized uptake value (SUVmax) measured on 18F-FDG PET/CT and mixed NSCLC components predict survival in surgical-resected combined small-cell lung cancer. J Cancer Res Clin Oncol. 2020 Oct;146(10):2595-2605 Authors: Hui Z, Wei F, Ren H, Xu W, Ren X Abstract PURPOSE: The combined small-cell lung cancer (c-SCLC) is rare and has unique clinicopathological futures. The aim of this study is to investigate 18F-FDG...
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Related Articles Combined microscope and endoscopy total resection of primary pineal malignant melanoma: case report and literature review. J Cancer Res Clin Oncol. 2020 Oct;146(10):2589-2594 Authors: Zhang J, Xiong Z, Chen J Abstract BACKGROUND: Primary pineal malignant melanoma (PPMM) is a rare entity of primary central nervous system melanomas, with only 26 cases reported in the literature to date. CASE PRESENTATION: We report the...
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Related Articles Triphasic waves in electroencephalogram as a possible early marker of carcinomatous meningitis: a case report. Medicine (Baltimore). 2020 Aug 14;99(33):e21735 Authors: Liu C, Cheng S, Ma Y, Liu C, Lv Y Abstract RATIONALE: Carcinomatous meningitis is a rare neurological complication. This condition is difficult to diagnose, and misdiagnosis is common because the clinical manifestations are variable. Cerebrospinal fluid (CSF)...
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Related Articles Primary breast diffuse large B-cell lymphoma in a patient with systemic lupus erythematosus: A case report and review of the literature. Medicine (Baltimore). 2020 Aug 14;99(33):e21736 Authors: Shen F, Li G, Jiang H, Zhao S, Qi F Abstract RATIONALE: Pilot studies have reported that patients with systemic lupus erythematosus (SLE) appear more likely to develop into neoplasia, especially lymphatic hyperplasia diseases. To our...
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Related Articles Intramuscular hemangioma with hemorrhagic transformation arising from paraspinal muscles of posterior neck: A case report. Medicine (Baltimore). 2020 Aug 14;99(33):e21741 Authors: Yu D, Choi JH, Jeon I Abstract RATIONALE: Hemangiomas are usually found in cutaneous or mucosal layers, less than 1% of hemangiomas develop in skeletal muscles. Intramuscular hemangioma (IH) in the head and neck areas is relatively infrequent, accounting...
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Related Articles Plasma exchange for treating anti-Yo-associated paraneoplastic cerebellar degeneration: Case report and literature review. Medicine (Baltimore). 2020 Aug 14;99(33):e21760 Authors: Hu FQ, Shang FR, Liu JJ, Yuan H Abstract RATIONALE: Paraneoplastic cerebellar degeneration (PCD) is a rare neurodegenerative syndrome associated with antibodies targeting the Purkinje cells of the cerebellum. Most cases of anti-Yo-associated PCD...
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Related Articles [Influence of genetic variation of programmed death-ligand 1 (PD-L1) on the prognosis of patients with non-small cell lung cancer who received platinum-based adjuvant chemotherapy]. Zhonghua Yi Xue Za Zhi. 2020 Sep 15;100(34):2682-2688 Authors: Zhang GW, Cheng RR, Zhang FR, Li P, Chu HY, Song XJ, Zhang GJ Abstract Objective: The aim of present study was to investigate the influence of genetic variation of programmed death-ligand...
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Related Articles Effects of Different n6/n3 PUFAs Dietary Ratio on Cardiac Diabetic Neuropathy. Nutrients. 2020 Sep 10;12(9): Authors: Urlić M, Urlić I, Urlić H, Mašek T, Benzon B, Vitlov Uljević M, Vukojević K, Filipović N Abstract We studied the influence of experimentally induced DM1, in combination with different dietary n6:n3 polyunsaturated fatty acid (PUFA) ratios on different types of nerve fibers in rat myocardium, in order to reveal...
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Related Articles Uncommon Site of Metastasis and Prolonged Survival in Patients with Anaplastic Thyroid Carcinoma: A Systematic Review of the Literature. Cancers (Basel). 2020 Sep 10;12(9): Authors: Mirabile A, Biafora M, Giordano L, Arrigoni G, Cangi MG, Dell'Oca I, Lira Luce F, Di Santo D, Galli A, Tulli M, Mellone R, Valsecchi D, Gregorc V, Bussi M Abstract Anaplastic thyroid carcinoma (ATC) is a very rare, highly aggressive malignant thyroid...
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Related Articles The Application of Virtual Reality in Cervical Spinal Surgery: A Review. World Neurosurg. 2020 Sep 12;: Authors: Yan C, Wu T, Huang K, He J, Liu H, Hong Y, Wang B Abstract In recent years, clinicians have used virtual reality (VR) to simulate real-world environments for medical purposes. The use of VR systems in the field of cervical spine surgery can lead to effective surgical training programs without causing harm to patients....
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Related Articles Application of optical frequency domain imaging to recanalized unruptured internal carotid artery aneurysm treated by flow-diverting stent-assisted coiling. World Neurosurg. 2020 Sep 12;: Authors: Neira RI, Yamada K, Shirakawa M, Uchida K, Yoshimura S Abstract Here we report the application of optical frequency domain imaging (OFDI), a new optical coherence tomography (OCT) device, for intravascular visualization in the treatment...
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Related Articles PedsQL score post encephalo-duro-arteriomyo synangiosis procedure for Moyamoya Disease: A single centre experience. World Neurosurg. 2020 Sep 12;: Authors: Kalra N, Bautista M, McCullagh H, Tyagi A Abstract BACKGROUND: Moyamoya disease is a progressive, occlusive arteriopathy of the intracranial vessels causing an increased risk of stroke. It often results in functional impairment and decrease in quality of life, both in the...
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Related Articles Allometry and advancing age significantly structure craniofacial variation in adult female baboons. J Anat. 2019 08;235(2):217-232 Authors: Joganic JL, Heuzé Y Abstract Primate craniofacial growth is traditionally assumed to cease upon maturation or at least be negligible, whereas bony remodeling is typically associated with advanced adult age and, in particular, tooth loss. Therefore, size and shape of the craniofacial skeleton...
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Related Articles Structural brain imaging as a diagnostic tool in dementia, why and how? Psychiatry Res Neuroimaging. 2020 Sep 04;:111183 Authors: Wahlund LO Abstract The demands for more people to be investigated due to cognitive failure and suspected dementia are increasing as increasing numbers of us get older and the incidence of dementia increases. An important part of a dementia study includes the structural imaging of the brain. Two imaging...
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Related Articles Approach to the Treatment of a Patient with an Aggressive Pituitary Tumor. J Clin Endocrinol Metab. 2020 Sep 15;: Authors: Lin AL, Donoghue MTA, Wardlaw SL, Yang TJ, Bodei L, Tabar V, Geer EB Abstract A small subset of pituitary adenomas grow despite maximal treatment with standard therapies; namely, surgery and radiotherapy. These aggressive tumors demonstrate two patterns of growth: they may be locally aggressive or metastasize...
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Related Articles Third ventricle hydatid cyst: A rare case report and review of the literature. Clin Neurol Neurosurg. 2020 Sep 08;198:106218 Authors: Samadian M, Mousavinejad SA, Jabbari A, Tavassol HH, Karimi P, Almagro K, Rezaei O, Borghei-Razavi H Abstract A primary intraventricular hydatid cyst is a very rare phenomenon, which is mostly located in the lateral ventricle. To the best of our knowledge, only two cases of third ventricle hydatid...
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Related Articles Risk-based Approaches for Optimizing Treatment in HER2-Positive Early Stage Breast Cancer. Semin Oncol. 2020 Aug 20;: Authors: Chiec L, Shah AN Abstract Advancements in the care for patients with early stage HER2-positive breast cancer is a story of incremental successes aimed at optimizing efficacy and reducing the toxicities of administered therapies. HER2 drives an aggressive breast cancer subtype that represents 15%-20%...
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Related Articles Combined inhibition of JAK2-STAT3 and SMO-GLI1/tGLI1 pathways suppresses breast cancer stem cells, tumor growth, and metastasis. Oncogene. 2020 Sep 14;: Authors: Doheny D, Sirkisoon S, Carpenter RL, Aguayo NR, Regua AT, Anguelov M, Manore SG, Arrigo A, Jalboush SA, Wong GL, Yu Y, Wagner CJ, Chan M, Ruiz J, Thomas A, Strowd R, Lin J, Lo HW Abstract Triple-negative breast cancer (TNBC) and HER2-positive breast cancer are particularly...
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