IJERPH, Vol. 17, Pages 6767: Accessing Occupational Health Services in the Southern African Development Community Region International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17186767 Authors: Masilu Daniel Masekameni Dingani Moyo Norman Khoza Chimwemwe Chamdimba Only 15% of the global population has access to occupational safety and health services. In Africa, only 5% of employees working from major establishments have access to occupational health...
IJERPH, Vol. 17, Pages 6766: SARS-CoV-2 Infections and Impact of the COVID-19 Pandemic in Pregnancy and Breastfeeding: Results from an Observational Study in Primary Care in Belgium International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17186766 Authors: Michael Ceulemans Jan Y. Verbakel Kristel Van Calsteren An Eerdekens Karel Allegaert Veerle Foulon COVID-19 also affects pregnant and breastfeeding women. Hence, clinicians and policymakers...
Atmosphere, Vol. 11, Pages 992: Modeling Ozone Source Apportionment and Performing Sensitivity Analysis in Summer on the North China Plain Atmosphere doi: 10.3390/atmos11090992 Authors: Yujing Zhang Yuncheng Zhao Jie Li Qizhong Wu Hui Wang Huiyun Du Wenyi Yang Zifa Wang Lili Zhu In recent years, air quality issues due to fine particulate matter have been sufficiently treated. However, ozone (O3) has now become the primary pollutant in summer on the North China...
Water, Vol. 12, Pages 2594: Coastal Vulnerability and Mitigation Strategies: From Monitoring to Applied Research Water doi: 10.3390/w12092594 Authors: Pasquale Contestabile Diego Vicinanza This paper intends to offer the readers an overview of the Special Issue on Coastal Vulnerability and Mitigation Strategies: From Monitoring to Applied Research. The main focus of this Special Issue is to provide the state-of-the-art and the recent research updates on the sustainable management...
Nutrients, Vol. 12, Pages 2840: Association of Dietary Patterns with Metabolic Syndrome Nutrients doi: 10.3390/nu12092840 Authors: Nicola Di Daniele Metabolic syndrome (MetS), as originally defined by Jean Vague in 1940, was identified as a cluster of chronic, inflammatory pathologies, such as arterial hypertension, abdominal obesity, high glucose levels, high triglyceride levels and low HDL levels in the blood [...]
Biomedicines, Vol. 8, Pages 357: Cinnamaldehyde and Hyperthermia Co-Treatment Synergistically Induces ROS-Mediated Apoptosis in ACHN Renal Cell Carcinoma Cells Biomedicines doi: 10.3390/biomedicines8090357 Authors: Chae Ryeong Ahn Jinbong Park Jai-Eun Kim Kwang Seok Ahn Young Woo Kim Minjeong Jeong Hong Jun Kim Sun Hyang Park Seung Ho Baek Renal cell carcinoma (RCC) represents the most common form of kidney cancer, which accounts for 3–5% newly diagnosed...
Recycling, Vol. 5, Pages 23: On the Production of Potassium Carbonate from Cocoa Pod Husks Recycling doi: 10.3390/recycling5030023 Authors: Kouwelton Kone Karl Akueson Graeme Norval Cocoa beans are found inside an outer husk; 60% of the cocoa fruit is the outer husk, which is a waste biomass. The husk cannot be used directly as a soil amendment as it promotes the fungal black pod disease, which reduces crop yield. The pods are segregated from the trees, and their plant nutrient...
Nanomaterials, Vol. 10, Pages 1856: Synthesis, Characterization and Process Optimization of Bone Whitlockite Nanomaterials doi: 10.3390/nano10091856 Authors: Sadaf Batool Usman Liaqat Zakir Hussain Manzar Sohail Whitlockite, being the second most abundant bio-mineral in living bone, finds huge applications in tissue regeneration and implants and its synthesis into its pure form has remained a challenge. Although precipitation of whitlockite phase has been reported recently in...
IJERPH, Vol. 17, Pages 6765: The Age Distribution among Children Seeking Medical Treatment for Precocious Puberty in Taiwan International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17186765 Authors: Pen-Hua Su Jing-Yang Huang Cho-Shun Li Hua-Pin Chang Objective: Children with precocious puberty (PP) may have increased physiological and psychological problems. In this study, we aimed to explore the trend of parents seeking medical care for their children...
Pathogens, Vol. 9, Pages 758: Modulation of the Functions of Goat Peripheral Blood Mononuclear Cells by Fasciola gigantica Thioredoxin Peroxidase In Vitro Pathogens doi: 10.3390/pathogens9090758 Authors: Ai-Ling Tian Xiaowei Tian Dan Chen Mingmin Lu Guillermo Calderón-Mantilla Xiao-Dan Yuan Xiangrui Li Hany M. Elsheikha Xing-Quan Zhu The liver fluke Fasciola gigantica has a remarkable ability to establish a long-term infection within the hepatobiliary system of...
IJMS, Vol. 21, Pages 6812: Mucolipidoses Overview: Past, Present, and Future International Journal of Molecular Sciences doi: 10.3390/ijms21186812 Authors: Shaukat A. Khan Saori C. Tomatsu Mucolipidosis II and III (ML II/III) are caused by a deficiency of uridine-diphosphate N-acetylglucosamine: lysosomal-enzyme-N-acetylglucosamine-1-phosphotransferase (GlcNAc-1-phosphotransferase, EC2.7.8.17), which tags lysosomal enzymes with a mannose 6-phosphate (M6P) marker for transport to the...
Vaccines, Vol. 8, Pages 537: Electroporation as the Immunotherapy Strategy for Cancer in Veterinary Medicine: State of the Art in Latin America Vaccines doi: 10.3390/vaccines8030537 Authors: Felipe Maglietti Matías Tellado Mariangela De Robertis Sebastián Michinski Juan Fernández Emanuela Signori Guillermo Marshall Electroporation is a technology that increases cell membrane permeability by the application of electric pulses. Electrochemotherapy (ECT), the best-known...
Geriatrics, Vol. 5, Pages 53: Comparison of the Effects of Visual and Auditory Distractions on Fistula Cannulation Pain among Older Patients Undergoing Hemodialysis: A Randomized Controlled Clinical Trial Geriatrics doi: 10.3390/geriatrics5030053 Authors: Mina Ghadimi Aghbolagh Tahereh Bahrami Nahid Rejeh Majideh Heravi-Karimooi Seyed Davood Tadrisi Mojtaba Vaismoradi Pain associated with fistula cannulation is a challenge for nurses who provide care to older patients...
Pathogens, Vol. 9, Pages 757: Evaluation of GVPC and BCYE Media for Legionella Detection and Enumeration in Water Samples by ISO 11731: Does Plating on BCYE Medium Really Improve Yield? Pathogens doi: 10.3390/pathogens9090757 Authors: Maria Scaturro Elisa Poznanski Mariarosaria Mupo Paola Blasior Margit Seeber Anna-Maria Prast Elisa Romanin Antonietta Girolamo Maria Cristina Rota Antonino Bella Maria Luisa Ricci Alberta Stenico Legionella spp are the...
Sci. Pharm., Vol. 88, Pages 39: Ethnopharmacology, Therapeutic Properties and Nutritional Potentials of Carpobrotus edulis: A Comprehensive Review Scientia Pharmaceutica doi: 10.3390/scipharm88030039 Authors: Akinyede Ekpo Oguntibeju Carpobrotus edulis, formerly known as Mesembryanthemum edule L, belongs to the Aizoaceae family of plants. It is a facultative halophytic invasive medicinal and edible succulent plant that is native to South Africa and is distributed worldwide....
Sci. Pharm., Vol. 88, Pages 38: Hydrolytic Stability of New Amino Acids Analogues of Memantine Scientia Pharmaceutica doi: 10.3390/scipharm88030038 Authors: Aleksandra Tencheva Radoslav Chayrov Petko Mandjukov Dancho Danalev Ivanka Stankova In the present work, the hydrolytic stability of new memantine analogues modified with amino acids, at different pH corresponding to the human biological liquids and organs, was evaluated. Memantine is an uncompetitive N-methyl-d-aspartate...
Particles, Vol. 3, Pages 642-659: Curvature Invariants for the Accelerating Natário Warp Drive Particles doi: 10.3390/particles3030042 Authors: Brandon Mattingly Abinash Kar Matthew Gorban William Julius Cooper K. Watson M.D. Ali Andrew Baas Caleb Elmore Jeffrey S. Lee Bahram Shakerin Eric W. Davis Gerald B. Cleaver A process for using curvature invariants is applied to evaluate the accelerating Natário warp drive. Curvature invariants are...
Diagnostics, Vol. 10, Pages 703: The Role of Imaging in Bladder Cancer Diagnosis and Staging Diagnostics doi: 10.3390/diagnostics10090703 Authors: Samuel J. Galgano Kristin K. Porter Constantine Burgan Soroush Rais-Bahrami Bladder cancer (BC) is the most common cancer of the urinary tract in the United States. Imaging plays a significant role in the management of patients with BC, including the locoregional staging and evaluation for distant metastatic disease, which cannot...
Biomolecules, Vol. 10, Pages 1327: Extracellular Vesicles as Nanotherapeutics for Parkinson’s Disease Biomolecules doi: 10.3390/biom10091327 Authors: Loredana Leggio Greta Paternò Silvia Vivarelli Francesca L’Episcopo Cataldo Tirolo Gabriele Raciti Fabrizio Pappalardo Carmela Giachino Salvatore Caniglia Maria Francesca Serapide Bianca Marchetti Nunzio Iraci Extracellular vesicles (EVs) are naturally occurring membranous structures secreted by normal and...
Brain Sciences, Vol. 10, Pages 641: Dynamic Cerebral Autoregulation Post Endovascular Thrombectomy in Acute Ischemic Stroke Brain Sciences doi: 10.3390/brainsci10090641 Authors: Faheem Sheriff Pedro Castro Mariel Kozberg Sarah LaRose Andrew Monk Elsa Azevedo Karen Li Sameen Jafari Shyam Rao Fadar Oliver Otite Ayaz Khawaja Farzaneh Sorond Steven Feske Can Ozan Tan Henrikas Vaitkevicius The development of the endovascular thrombectomy (EVT) technique...
Antioxidants, Vol. 9, Pages 875: Phototherapy as a Rational Antioxidant Treatment Modality in COVID-19 Management; New Concept and Strategic Approach: Critical Review Antioxidants doi: 10.3390/antiox9090875 Authors: Reem Hanna Snehal Dalvi Tudor Sălăgean Ioana Roxana Bordea Stefano Benedicenti The COVID-19 pandemic has taken the entire globe by storm. The pathogenesis of this virus has shown a cytokine storm release, which contributes to critical or severe multi-organ failure....
IJMS, Vol. 21, Pages 6811: Gene Expression Signature of Acquired Chemoresistance in Neuroblastoma Cells International Journal of Molecular Sciences doi: 10.3390/ijms21186811 Authors: Mohamed Jemaà Wondossen Sime Yasmin Abassi Vito Alessandro Lasorsa Julie Bonne Køhler Martin Michaelis Jindrich Cinatl Cinatl, Jr. Mario Capasso Ramin Massoumi Drug resistance of childhood cancer neuroblastoma is a serious clinical problem. Patients with relapsed disease have a poor...
IJMS, Vol. 21, Pages 6810: Antimicrobial Peptides with Enhanced Salt Resistance and Antiendotoxin Properties International Journal of Molecular Sciences doi: 10.3390/ijms21186810 Authors: Hung-Lun Chu Ya-Han Chih Kuang-Li Peng Chih-Lung Wu Hui-Yuan Yu Doris Cheng Yu-Ting Chou Jya-Wei Cheng A strategy was described to design antimicrobial peptides (AMPs) with enhanced salt resistance and antiendotoxin activities by linking two helical AMPs with the Ala-Gly-Pro (AGP)...
IJERPH, Vol. 17, Pages 6763: Assessing Productivity Development of Public Hospitals: A Case Study of Shanghai, China International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17186763 Authors: Juan Du Shuhong Cui Hong Gao As the main provider of medical services for the general public, the productivity changes of public hospitals directly reflect the development of the healthcare system and the implementation effect of medical reform policies. Using the...
IJERPH, Vol. 17, Pages 6762: Impacts of COVID-19 on Electronic Cigarette Purchasing, Use and Related Behaviors International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17186762 Authors: Eric K. Soule Shannon Mayne William Snipes Mignonne C. Guy Alison Breland Pebbles Fagan Background: COVID-19 has caused health impacts and disruptions globally. Electronic cigarette (ECIG) users may face additional impacts. This study examined impacts of COVID-19...
IJERPH, Vol. 17, Pages 6764: Is Fear of Harm (FoH) in Sports-Related Activities a Latent Trait? The Item Response Model Applied to the Photographic Series of Sports Activities for Anterior Cruciate Ligament Rupture (PHOSA-ACLR) International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17186764 Authors: Wim van Lankveld Ron J. Pat-El Nicky van Melick Robert van Cingel J. Bart Staal Background: Fear of Harm (FoH) predicts return to sports in Anterior...
Nanomaterials, Vol. 10, Pages 1855: Experimental Research and Development on the Natural Convection of Suspensions of Nanoparticles—A Comprehensive Review Nanomaterials doi: 10.3390/nano10091855 Authors: S M Sohel Murshed Mohsen Sharifpur Solomon Giwa Josua P. Meyer Suspensions of nanoparticles, widely known as nanofluids, are considered as advanced heat transfer media for thermal management and conversion systems. Research on their convective thermal transport is of paramount...
Biomolecules, Vol. 10, Pages 1326: Isolation of Cysteine-Rich Peptides from Citrullus colocynthis Biomolecules doi: 10.3390/biom10091326 Authors: Behzad Shahin-Kaleybar Ali Niazi Alireza Afsharifar Ghorbanali Nematzadeh Reza Yousefi Bernhard Retzl Roland Hellinger Edin Muratspahić Christian W. Gruber The plant Citrullus colocynthis, a member of the squash (Cucurbitaceae) family, has a long history in traditional medicine. Based on the ancient knowledge about the...
Cancers, Vol. 12, Pages 2649: Erratum: Lee, H.H., et al. Histone 2A Family Member J Drives Mesenchymal Transition and Temozolomide Resistance in Glioblastoma Multiforme. Cancers 2020, 12, 98 Cancers doi: 10.3390/cancers12092649 Authors: Hsun-Hua Lee Che-Hsuan Lin Hui-Yu Lin Chia-Hao Kuei Jing-Quan Zheng Yuan-Hung Wang Long-Sheng Lu Fei-Peng Lee Chaur-Jong Hu Dean Wu Yuan-Feng Lin The authors wish to make the following changes to this paper [...]
Cancers, Vol. 12, Pages 2650: Essential Oils and Their Main Chemical Components: The Past 20 Years of Preclinical Studies in Melanoma Cancers doi: 10.3390/cancers12092650 Authors: Marta Di Martile Stefania Garzoli Rino Ragno Donatella Del Bufalo The last two decades have seen the development of effective therapies, which have saved the lives of a large number of melanoma patients. However, therapeutic options are still limited for patients without BRAF mutations or in relapse...
Antibiotics, Vol. 9, Pages 609: Strategies to Reduce Biofilm Formation in PEEK Materials Applied to Implant Dentistry—A Comprehensive Review Antibiotics doi: 10.3390/antibiotics9090609 Authors: Renata Scheeren Brum Luiza Gomes Labes Cláudia Ângela Maziero Volpato César Augusto Magalhães Benfatti Andrea de Lima Pimenta Polyether-ether-ketone (PEEK) has emerged in Implant Dentistry with a series of short-time applications and as a promising material to substitute definitive...
Antibiotics, Vol. 9, Pages 610: Point-of-Care C-Reactive Protein Testing to Reduce Antibiotic Prescribing for Respiratory Tract Infections in Primary Care: Systematic Review and Meta-Analysis of Randomised Controlled Trials Antibiotics doi: 10.3390/antibiotics9090610 Authors: Martínez-González Keizer Plate Coenen Valeri Verbakel Rosemann Neuner-Jehle Senn C-reactive protein (CRP) point-of-care testing (POCT) is increasingly being promoted to reduce diagnostic...
Microorganisms, Vol. 8, Pages 1423: Fatty Acids from Hermetia illucens Larvae Fat Inhibit the Proliferation and Growth of Actual Phytopathogens Microorganisms doi: 10.3390/microorganisms8091423 Authors: Elena Marusich Heakal Mohamed Yuriy Afanasev Sergey Leonov The rapid increase of plant diseases caused by bacterial phytopathogens calls for an urgent search for new antibacterials. Antimicrobial compounds of natural origin stand up as frontiers in the attempts of the antibiotic...
Metabolites, Vol. 10, Pages 373: Metabolic Profiling of a Porcine Combat Trauma-Injury Model Using NMR and Multi-Mode LC-MS Metabolomics—A Preliminary Study Metabolites doi: 10.3390/metabo10090373 Authors: Anna Karen Carrasco Laserna Yiyang Lai Guihua Fang Rajaseger Ganapathy Mohamed Shirhan Bin Mohamed Atan Jia Lu Jian Wu Mahesh Uttamchandani Shabbir M Moochhala Sam Fong Yau Li Profiles of combat injuries worldwide have shown that penetrating trauma is one...
Plants, Vol. 9, Pages 1215: Physiological Approach to the Use of the Natural Compound Quinate in the Control of Sensitive and Resistant Papaver rhoeas Plants doi: 10.3390/plants9091215 Authors: Ana Zabalza Ainhoa Zulet-González Maria Barco-Antoñanzas Mikel V. Eceiza Miriam Gil-Monreal Mercedes Royuela Quinate (1,3,4,5-tetrahydroxycyclohexanecarboxylate) is a compound synthesized in plants through a side-branch of the shikimate biosynthesis pathway, which is accumulated...
Plants, Vol. 9, Pages 1216: Potassium Efflux and Cytosol Acidification as Primary Anoxia-Induced Events in Wheat and Rice Seedlings Plants doi: 10.3390/plants9091216 Authors: Vladislav V. Yemelyanov Tamara V. Chirkova Maria F. Shishova Sylvia M. Lindberg Both ion fluxes and changes of cytosolic pH take an active part in the signal transduction of different environmental stimuli. Here we studied the anoxia-induced alteration of cytosolic K+ concentration, [K+]cyt, and cytosolic...
Biomedicines, Vol. 8, Pages 355: The Inhibition of Complement System in Formal and Emerging Indications: Results from Parallel One-Stage Pairwise and Network Meta-Analyses of Clinical Trials and Real-Life Data Studies Biomedicines doi: 10.3390/biomedicines8090355 Authors: Coralina Bernuy-Guevara Hassib Chehade Yannick D. Muller Julien Vionnet François Cachat Gabriella Guzzo Carlos Ochoa-Sangrador F. Javier Álvarez Daniel Teta Débora Martín-García Marcel Adler...
Biomedicines, Vol. 8, Pages 356: Accurate Measurement of Copper Overload in an Experimental Model of Wilson Disease by Laser Ablation Inductively Coupled Plasma Mass Spectrometry Biomedicines doi: 10.3390/biomedicines8090356 Authors: Philipp Kim Chengcheng Christine Zhang Sven Thoröe-Boveleth Sabine Weiskirchen Nadine Therese Gaisa Eva Miriam Buhl Wolfgang Stremmel Uta Merle Ralf Weiskirchen Wilson disease is a rare inherited autosomal recessive disorder. As a...
IJMS, Vol. 21, Pages 6809: The Effect of miR-146a on the Gene Expression of Immunoregulatory Cytokines in Human Mesenchymal Stromal Cells International Journal of Molecular Sciences doi: 10.3390/ijms21186809 Authors: Jung Hwa Ko Joo Youn Oh Mounting evidence indicates that microRNAs (miRNAs), including miR-146a, have an impact on the immunomodulatory activities of mesenchymal stem/stromal cells (MSCs). Suppression of inflammatory macrophage activation is one of the main immunomodulatory...
MTI, Vol. 4, Pages 67: Aligning Realities: Correlating Content between Projected and Head Worn Displays Multimodal Technologies and Interaction doi: 10.3390/mti4030067 Authors: James Walsh Bruce H. Thomas Enabling the effective representation of an object’s position and depth in augmented reality (AR) is crucial not just for realism, but also to enable augmented reality’s wider utilization in real world applications. Domains such as architecture and building design...
IJERPH, Vol. 17, Pages 6760: Latent Profiles of Burnout, Self-Esteem and Depressive Symptomatology among Teachers International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17186760 Authors: Inmaculada Méndez Juan Pedro Martínez-Ramón Cecilia Ruiz-Esteban José Manuel García-Fernández Burnout is a reality in the teaching profession. Specifically, teaching staff usually have higher burnout rates. The present study aims to analyze the different burnout...
IJERPH, Vol. 17, Pages 6761: Measurement of Personal Experienced Temperature Variations in Rural Households Using Wearable Monitors: A Pilot Study International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17186761 Authors: Rongjiang Ma Yu Fu Mengsi Deng Xingli Ding Jill Baumgartner Ming Shan Xudong Yang The time-varying data of air temperatures experienced by people in their daily lives is an important basis for studying human thermal sensation,...
Viruses, Vol. 12, Pages 1030: Detection and Phylogenetic Analyses of Taura Syndrome Virus from Archived Davidson’s-Fixed Paraffin-Embedded Shrimp Tissue Viruses doi: 10.3390/v12091030 Authors: Lauren Marie Ochoa Roberto Cruz-Flores Arun K. Dhar Taura syndrome is a World Organization for Animal Health (OIE)-listed disease of marine shrimp that is caused by Taura syndrome virus (TSV), a single-stranded RNA virus. Here we demonstrate the utility of using 15-year-old archived Davidson’s-fixed...
Viruses, Vol. 12, Pages 1031: Avian Influenza Virus Prevalence and Subtype Diversity in Wild Birds in Shanghai, China, 2016–2018 Viruses doi: 10.3390/v12091031 Authors: Ling Tang Wangjun Tang Xiaofang Li Chuanxia Hu Di Wu Tianhou Wang Guimei He From 2016 to 2018, surveillance of influenza A viruses in wild birds was conducted in Shanghai, located at the East Asian–Australian flyway, China. A total of 5112 samples from 51 species of wild birds were collected...
Viruses, Vol. 12, Pages 1032: Abrogating ALIX Interactions Results in Stuttering of the ESCRT Machinery Viruses doi: 10.3390/v12091032 Authors: Shilpa Gupta Mourad Bendjennat Saveez Saffarian Endosomal sorting complexes required for transport (ESCRT) proteins assemble on budding cellular membranes and catalyze their fission. Using live imaging of HIV virions budding from cells, we followed recruitment of ESCRT proteins ALIX, CHMP4B and VPS4. We report that the ESCRT proteins transiently...
Religions, Vol. 11, Pages 472: The Mystical World of the Body in the Bengali Tantric Work Nigūḍhārthaprakāśāvali Religions doi: 10.3390/rel11090472 Authors: Robert Czyżykowski Amongst the wide collection of literature on the Bengali Tantric Vaiṣṇava Sahajiyās, the works of Mukundadāsa (or Mukundadeva) and his disciples are counted among the most influential. Those Middle Bengali texts that are usually recognized as a group of the four main texts of Mukunda and his circle or followers...
Children, Vol. 7, Pages 140: Efficacy of Olanzapine for High and Moderate Emetogenic Chemotherapy in Children Children doi: 10.3390/children7090140 Authors: So Rae Lee Su Min Kim Min Young Oh Jae Min Lee This study was conducted to investigate the safety and efficacy of olanzapine for high and moderate emetogenic chemotherapy in children and young adults. We retrospectively reviewed the records of pediatric patients (n = 13) with cancer who had been administered olanzapine as...
Atmosphere, Vol. 11, Pages 991: Temporal Variation and Source Analysis of Carbonaceous Aerosol in Industrial Cities of Northeast China during the Spring Festival: The Case of Changchun Atmosphere doi: 10.3390/atmos11090991 Authors: Mengduo Zhang Shichun Zhang Qiuyang Bao Chengjiang Yang Yang Qin Jing Fu Weiwei Chen Carbonaceous aerosol, one of the major components of atmospheric aerosols, significantly affects haze episodes, climate change, and human health. Northeastern...
Pathogens, Vol. 9, Pages 755: Significance of Anti-Nuclear Antibodies and Cryoglobulins in Patients with Acute and Chronic HEV Infection Pathogens doi: 10.3390/pathogens9090755 Authors: Thomas Horvatits Julian Schulze zur Wiesch Susanne Polywka Gustav Buescher Marc Lütgehetmann Elaine Hussey Karoline Horvatits Sven Peine Friedrich Haag Marylyn M. Addo Ansgar W. Lohse Christina Weiler-Normann Sven Pischke Background: Hepatitis E virus (HEV) has been...
Pathogens, Vol. 9, Pages 754: Pathogenic Delivery: The Biological Roles of Cryptococcal Extracellular Vesicles Pathogens doi: 10.3390/pathogens9090754 Authors: Haroldo C. de Oliveira Rafael F. Castelli Flavia C. G. Reis Juliana Rizzo Marcio L. Rodrigues Extracellular vesicles (EVs) are produced by all domains of life. In fungi, these structures were first described in Cryptococcus neoformans and, since then, they were characterized in several pathogenic and non-pathogenic...
Pathogens, Vol. 9, Pages 756: Fast-Growing Alveolar Echinococcosis Following Lung Transplantation Pathogens doi: 10.3390/pathogens9090756 Authors: Clarisse Dupont Fréderic Grenouillet Jean-Yves Mabrut Frédérique Gay Florence Persat Martine Wallon Jean-François Mornex François Philit Damien Dupont Alveolar echinococcosis is a rare but life-threatening infection caused by the parasite Echinococcus multilocularis. Its natural history is characterized by a slow parasitic...
IJERPH, Vol. 17, Pages 6759: Analysis of Low Cancer Mortality Rates in the Wine Regions of Tokaj and Balaton in Hungary International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17186759 Authors: Sándor Sipka János Nagy Péter Sipka Judit Kocsis Judit Tóth Péter Árkosy Zsolt Horváth The age-adjusted death rates (AADRs) due to cancers were investigated in two historical regions of white wines (Tokaj and Balaton) and in Hódmezővásárhely...
IJMS, Vol. 21, Pages 6807: Clinical and Molecular Landscape of ALS Patients with SOD1 Mutations: Novel Pathogenic Variants and Novel Phenotypes. A Single ALS Center Study International Journal of Molecular Sciences doi: 10.3390/ijms21186807 Authors: Emilien Bernard Antoine Pegat Juliette Svahn Françoise Bouhour Pascal Leblanc Stéphanie Millecamps Stéphane Thobois Claire Guissart Serge Lumbroso Kevin Mouzat Mutations in the copper zinc superoxide dismutase 1...
IJMS, Vol. 21, Pages 6806: Three-Dimensional Cell Cultures as an In Vitro Tool for Prostate Cancer Modeling and Drug Discovery International Journal of Molecular Sciences doi: 10.3390/ijms21186806 Authors: Fabrizio Fontana Michela Raimondi Monica Marzagalli Michele Sommariva Nicoletta Gagliano Patrizia Limonta In the last decade, three-dimensional (3D) cell culture technology has gained a lot of interest due to its ability to better recapitulate the in vivo organization...
IJMS, Vol. 21, Pages 6808: High-Temperature-Responsive Poplar lncRNAs Modulate Target Gene Expression via RNA Interference and Act as RNA Scaffolds to Enhance Heat Tolerance International Journal of Molecular Sciences doi: 10.3390/ijms21186808 Authors: Yuepeng Song Panfei Chen Peng Liu Chenhao Bu Deqiang Zhang High-temperature stress is a threat to plant development and survival. Long noncoding RNAs (lncRNAs) participate in plant stress responses, but their functions in the...
IJERPH, Vol. 17, Pages 6758: Association between Presenteeism, Psychosocial Aspects of Work and Common Mental Disorders among Nursing Personnel International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17186758 Authors: Aline Silva-Costa Pollyana C. S. Ferreira Rosane H. Griep Lucia Rotenberg Presenteeism is the term used to describe going in to work even with a health problem. The phenomenon has been identified as one prior factor in sickness absence...
Vaccines, Vol. 8, Pages 534: Vaccination into the Dermal Compartment: Techniques, Challenges, and Prospects Vaccines doi: 10.3390/vaccines8030534 Authors: Johanna Hettinga Robert Carlisle In 2019, an ‘influenza pandemic’ and ‘vaccine hesitancy’ were listed as two of the top 10 challenges to global health by the WHO. The skin is a unique vaccination site, due to its immune-rich milieu, which is evolutionarily primed to respond to challenge, and...
Vaccines, Vol. 8, Pages 536: Effectiveness of a Simultaneous rHVT-F(ND) and rHVT-H5(AI) Vaccination of Day-Old Chickens and the Influence of NDV- and AIV-Specific MDA on Immune Response and Conferred Protection Vaccines doi: 10.3390/vaccines8030536 Authors: Fabienne Rauw Eva Ngabirano Yannick Gardin Vilmos Palya Bénédicte Lambrecht The recombinant herpesvirus of turkey (rHVT) vaccines targeting Newcastle disease (ND) and H5Nx avian influenza (AI) have been demonstrated efficient...
Vaccines, Vol. 8, Pages 535: Relationship between Influenza Vaccination Coverage Rate and COVID-19 Outbreak: An Italian Ecological Study Vaccines doi: 10.3390/vaccines8030535 Authors: Mauro Amato José Pablo Werba Beatrice Frigerio Daniela Coggi Daniela Sansaro Alessio Ravani Palma Ferrante Fabrizio Veglia Elena Tremoli Damiano Baldassarre Background: The lack of specific vaccines or drugs against coronavirus disease 2019 (COVID-19) warrants studies focusing...
Vaccines, Vol. 8, Pages 533: Evaluation of Antibody Response Directed against Porcine Reproductive and Respiratory Syndrome Virus Structural Proteins Vaccines doi: 10.3390/vaccines8030533 Authors: Hung Q. Luong Huong T. L. Lai Hiep L. X. Vu Luciferase-immunoprecipitation system (LIPS), a liquid phase immunoassay, was used to evaluate antibody responses directed against the structural proteins of PRRSV in pigs that were experimentally infected with virulent PRRSV strains. First,...
Cells, Vol. 9, Pages 2108: Raloxifene and n-acetylcysteine Ameliorate TGF-Signalling in Fibroblasts from Patients with Recessive Dominant Epidermolysis Bullosa Cells doi: 10.3390/cells9092108 Authors: Tania Aguado Marta García Adela García Gemma Ferrer-Mayorga Lucía Martínez-Santamaría Marcela del Río Luisa-María Botella José-María Sánchez-Puelles Recessive dystrophic epidermolysis bullosa (RDEB) is a severe skin disease caused by mutation of the COL7A1 gene. RDEB...
Cells, Vol. 9, Pages 2111: Exercise-Induced Changes in Bioactive Lipids Might Serve as Potential Predictors of Post-Exercise Hypotension. A Pilot Study in Healthy Volunteers Cells doi: 10.3390/cells9092111 Authors: Miriam C. Wolters Julia Schmetzer Christine V. Möser Lisa Hahnefeld Carlo Angioni Dominique Thomas Nerea Ferreirós Gerd Geisslinger Ellen Niederberger Post-exercise hypotension (PEH) is the phenomenon of lowered blood pressure after a single bout of...
Cells, Vol. 9, Pages 2109: Lessons from Bacillus Calmette-Guérin: Harnessing Trained Immunity for Vaccine Development Cells doi: 10.3390/cells9092109 Authors: Samuel T. Pasco Juan Anguita Vaccine design traditionally focuses on inducing adaptive immune responses against a sole target pathogen. Considering that many microbes evade innate immune mechanisms to initiate infection, and in light of the discovery of epigenetically mediated innate immune training, the paradigm of vaccine...
Cells, Vol. 9, Pages 2110: Maintenance Therapy for ATM-Deficient Pancreatic Cancer by Multiple DNA Damage Response Interferences after Platinum-Based Chemotherapy Cells doi: 10.3390/cells9092110 Authors: Elodie Roger Johann Gout Frank Arnold Alica K. Beutel Martin Müller Alireza Abaei Thomas F. E. Barth Volker Rasche Thomas Seufferlein Lukas Perkhofer Alexander Kleger Personalized medicine in treating pancreatic ductal adenocarcinoma (PDAC) is still in its...
Toxins, Vol. 12, Pages 599: First Detection of Tetrodotoxin in Bivalves and Gastropods from the French Mainland Coasts Toxins doi: 10.3390/toxins12090599 Authors: Vincent Hort Nathalie Arnich Thierry Guérin Gwenaëlle Lavison-Bompard Marina Nicolas In 2015, tetrodotoxins (TTXs) were considered a potential threat in Europe since several studies had shown the presence of these toxins in European bivalve molluscs. In this study, we investigated the occurrence of TTXs in 127 bivalve...
Toxins, Vol. 12, Pages 600: Making 3D-Cry Toxin Mutants: Much More Than a Tool of Understanding Toxins Mechanism of Action Toxins doi: 10.3390/toxins12090600 Authors: Susana Vílchez 3D-Cry toxins, produced by the entomopathogenic bacterium Bacillus thuringiensis, have been extensively mutated in order to elucidate their elegant and complex mechanism of action necessary to kill susceptible insects. Together with the study of the resistant insects, 3D-Cry toxin mutants represent one of...
JCM, Vol. 9, Pages 2994: The Impact of Hypoxic Hepatitis on Clinical Outcomes after Extracorporeal Cardiopulmonary Resuscitation Journal of Clinical Medicine doi: 10.3390/jcm9092994 Authors: Yun Im Lee Min Goo Kang Ryoung-Eun Ko Taek Kyu Park Chi Ryang Chung Yang Hyun Cho Kyeongman Jeon Gee Young Suh Jeong Hoon Yang Although there have been several reports regarding the association between hypoxic hepatic injury and clinical outcomes in patients who underwent...
Foods, Vol. 9, Pages 1308: Inter-Relationships between Test Weight, Thousand Kernel Weight, Kernel Size Distribution and Their Effects on Durum Wheat Milling, Semolina Composition and Pasta Processing Quality Foods doi: 10.3390/foods9091308 Authors: Kun Wang Bin Xiao Fu Although most of the durum wheat produced in the Canadian prairies in 2017 and 2018 met the test weight (TW) requirements for the top grades of Canada Western Amber Durum (CWAD), some samples of top grades were inferior...
IJERPH, Vol. 17, Pages 6756: Outcomes of Consumer Involvement in Mental Health Nursing Education: An Integrative Review International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17186756 Authors: Kang Joung This integrative review analyzed the research on consumer involvement in mental health nursing education in the last decade. We aimed to derive the main contents, methods, and outcomes of education using consumer involvement for mental health nursing...
IJERPH, Vol. 17, Pages 6757: Health Impact Assessment of Artisanal and Small-Scale Gold Mining Area in Myanmar, Mandalay Region: Preliminary Research International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17186757 Authors: Kyaw Kuang Sakakibara Increasing artisanal and small-scale gold mining (ASGM) in developing countries has raised health concerns in mining communities. A preliminary health survey was conducted in Thabeikkyin Township, Mandalay...
Molecules, Vol. 25, Pages 4243: Poly-(Lactic-co-Glycolic) Acid Nanoparticles for Synergistic Delivery of Epirubicin and Paclitaxel to Human Lung Cancer Cells Molecules doi: 10.3390/molecules25184243 Authors: Nikita Sharma R. Mankamna Kumari Nidhi Gupta Asad Syed Ali H. Bahkali Surendra Nimesh Combination therapy using chemically distinct drugs has appeared as one of the promising strategies to improve anticancer treatment efficiency. In the present investigation, poly-(lactic-co-glycolic)...
Molecules, Vol. 25, Pages 4256: Optimization of Light Intensity, Temperature, and Nutrients to Enhance the Bioactive Content of Hyperforin and Rutin in St. John’s Wort Molecules doi: 10.3390/molecules25184256 Authors: Chia-Hung Kuo Yi-Chin Chou Kuo-Chun Liao Chwen-Jen Shieh Tzu-Shing Deng St. John’s wort (Hypericum perforatum L.) is a medicinal plant that alleviates depression and other disorders due to its abundance of active ingredients. Hyperforin, rutin, and...
Molecules, Vol. 25, Pages 4246: Shape-Memory Polymeric Artificial Muscles: Mechanisms, Applications and Challenges Molecules doi: 10.3390/molecules25184246 Authors: Yujie Chen Chi Chen Hafeez Ur Rehman Xu Zheng Hua Li Hezhou Liu Mikael S. Hedenqvist Shape-memory materials are smart materials that can remember an original shape and return to their unique state from a deformed secondary shape in the presence of an appropriate stimulus. This property allows these materials...
Molecules, Vol. 25, Pages 4255: Activated Carbons and Their Evaluation in Electric Double Layer Capacitors Molecules doi: 10.3390/molecules25184255 Authors: Krzysztof Kierzek Grażyna Gryglewicz This review presents a summary of the manufacturing of activated carbons (ACs) as electrode materials for electric double layer capacitors. Commonly used techniques of open and closed porosity determination (gas adsorption, immersion calorimetry, X-ray and neutrons scattering) were briefly...
Molecules, Vol. 25, Pages 4248: Five Novel Non-Sialic Acid-Like Scaffolds Inhibit In Vitro H1N1 and H5N2 Neuraminidase Activity of Influenza a Virus Molecules doi: 10.3390/molecules25184248 Authors: Luis Márquez-Domínguez Julio Reyes-Leyva Irma Herrera-Camacho Gerardo Santos-López Thomas Scior Neuraminidase (NA) of influenza viruses enables the virus to access the cell membrane. It degrades the sialic acid contained in extracellular mucin. Later, it is responsible for releasing...
Molecules, Vol. 25, Pages 4254: Antiproliferative and Pro-Apoptotic Effect of Uvaol in Human Hepatocarcinoma HepG2 Cells by Affecting G0/G1 Cell Cycle Arrest, ROS Production and AKT/PI3K Signaling Pathway Molecules doi: 10.3390/molecules25184254 Authors: Gloria C. Bonel-Pérez Amalia Pérez-Jiménez Isabel Gris-Cárdenas Alberto M. Parra-Pérez José Antonio Lupiáñez Fernando J. Reyes-Zurita Eva Siles René Csuk Juan Peragón Eva E. Rufino-Palomares Natural products...
Molecules, Vol. 25, Pages 4245: Peptides with Dual Antimicrobial–Anticancer Activity: Strategies to Overcome Peptide Limitations and Rational Design of Anticancer Peptides Molecules doi: 10.3390/molecules25184245 Authors: Yamil Liscano Jose Oñate-Garzón Jean Paul Delgado Peptides are naturally produced by all organisms and exhibit a wide range of physiological, immunomodulatory, and wound healing functions. Furthermore, they can provide with protection against microorganisms and...
Molecules, Vol. 25, Pages 4253: Synthesis of Organosilicon Ligands for Europium (III) and Gadolinium (III) as Potential Imaging Agents Molecules doi: 10.3390/molecules25184253 Authors: James I. Bruce Patrick J. O’Connell Peter G. Taylor David P.T. Smith Roy C. Adkin Victoria K. Pearson The relaxivity of MRI contrast agents can be increased by increasing the size of the contrast agent and by increasing concentration of the bound gadolinium. Large multi-site ligands able...
Molecules, Vol. 25, Pages 4239: Coupling of HSP72 α-Helix Subdomains by the Unexpected Irreversible Targeting of Lysine-56 over Cysteine-17; Coevolution of Covalent Bonding Molecules doi: 10.3390/molecules25184239 Authors: Aimen Aljoundi Ahmed El Rashedy Patrick Appiah-Kubi Mahmoud E. S. Soliman Covalent inhibition has recently gained a resurgence of interest in several drug discovery areas. The expansion of this approach is based on evidence elucidating the selectivity and...
Molecules, Vol. 25, Pages 4252: New Heteroleptic 3D Metal Complexes: Synthesis, Antimicrobial and Solubilization Parameters Molecules doi: 10.3390/molecules25184252 Authors: Muhammad Babar Taj Muneera D. F. Alkahtani Uzma Ali Ahmad Raheel Walla Alelwani Afnan M. Alnajeebi Nouf Abubakr Babteen Sadia Noor Heba Alshater The microbial resistance to current antibiotics is increasing day by day, which in turn accelerating the development of new effective drugs. Several...
Molecules, Vol. 25, Pages 4247: Probing the Highly Disparate Dual Inhibitory Mechanisms of Novel Quinazoline Derivatives against Mycobacterium tuberculosis Protein Kinases A and B Molecules doi: 10.3390/molecules25184247 Authors: Fisayo A. Olotu Mahmoud E. Soliman Mycobacterium tuberculosis (Mtb) serine/threonine (Ser/Thr) Protein kinases A (PknA) and B (PknB) have been identified as highly attractive targets for overcoming drug resistant tuberculosis. A recent lead series optimization...
Molecules, Vol. 25, Pages 4251: Study of Antioxidant Properties of Agents from the Perspective of Their Action Mechanisms Molecules doi: 10.3390/molecules25184251 Authors: Alla Ivanova Elena Gerasimova Elena Gazizullina The creation and analysis of a large variety of existing methods for the evaluation of integrated antioxidant properties are quite relevant in connection with a range of biological mechanisms of the antioxidants (AO) action. In this work, the existing methods are...
Molecules, Vol. 25, Pages 4244: 6-Arylimino-2-(2-(1-phenylethyl)naphthalen-1-yl)-iminopyridylmetal (Fe and Co) Complexes as Highly Active Precatalysts for Ethylene Polymerization: Influence of Metal and/or Substituents on the Active, Thermostable Performance of Their Complexes and Resultant Polyethylenes Molecules doi: 10.3390/molecules25184244 Authors: Wenhua Lin Liping Zhang Jiahao Gao Qiuyue Zhang Yanping Ma Hua Liu Wen-Hua Sun A series of 6-arylimino-2-(2-(1-phenylethyl)naphthalen-1-yl)iminopyridines...
Molecules, Vol. 25, Pages 4250: In Vitro Antimicrobial Activity of Isopimarane-Type Diterpenoids Molecules doi: 10.3390/molecules25184250 Authors: Vera M. S. Isca Joana Andrade Ana Sofia Fernandes Paulo Paixão Clara Uriel Ana María Gómez Noélia Duarte Patrícia Rijo The antimicrobial evaluation of twelve natural and hemisynthetic isopimarane diterpenes are reported. The compounds were evaluated against a panel of Gram-positive bacteria, including two methicillin-resistant...
Molecules, Vol. 25, Pages 4242: Template Synthesis of Porous Ceria-Based Catalysts for Environmental Application Molecules doi: 10.3390/molecules25184242 Authors: Igor Yu. Kaplin Ekaterina S. Lokteva Elena V. Golubina Valery V. Lunin Porous oxide materials are widely used in environmental catalysis owing to their outstanding properties such as high specific surface area, enhanced mass transport and diffusion, and accessibility of active sites. Oxides of metals with variable...
Molecules, Vol. 25, Pages 4249: The Physiochemical Properties and Adsorption Characteristics of Processed Pomelo Peel as a Carrier for Epigallocatechin-3-Gallate Molecules doi: 10.3390/molecules25184249 Authors: Liangyu Wu Guoying Zhang Jinke Lin The NaOH-HCl- and ethanol-pretreated pomelo peel samples were prepared to apply to the batch adsorption for epigallocatechin-3-gallate (EGCG). The characteristics of peel samples were determined by Fourier transform infrared spectroscopy,...
Molecules, Vol. 25, Pages 4241: Development and Optimization of a High Sensitivity LC-MS/MS Method for the Determination of Hesperidin and Naringenin in Rat Plasma: Pharmacokinetic Approach Molecules doi: 10.3390/molecules25184241 Authors: Jesús Alfredo Araujo-León Rolffy Ortiz-Andrade Rivelino Armando Vera-Sánchez Julio Enrique Oney-Montalvo Tania Isolina Coral-Martínez Zulema Cantillo-Ciau The purpose of this study was to develop, optimize, and fully validate a high-sensitivity...
Molecules, Vol. 25, Pages 4240: Elaeagnus angustifolia Plant Extract Inhibits Epithelial-Mesenchymal Transition and Induces Apoptosis via HER2 Inactivation and JNK Pathway in HER2-Positive Breast Cancer Cells Molecules doi: 10.3390/molecules25184240 Authors: Ayesha Jabeen Anju Sharma Ishita Gupta Hadeel Kheraldine Semir Vranic Ala-Eddin Al Moustafa Halema F. Al Farsi Elaeagnus angustifolia (EA) is a medicinal plant used for treating several human diseases in the Middle...
Molecules, Vol. 25, Pages 4257: Biased Opioid Ligands Molecules doi: 10.3390/molecules25184257 Authors: Abdelfattah Faouzi Balazs R. Varga Susruta Majumdar Achieving effective pain management is one of the major challenges associated with modern day medicine. Opioids, such as morphine, have been the reference treatment for moderate to severe acute pain not excluding chronic pain modalities. Opioids act through the opioid receptors, the family of G-protein coupled receptors (GPCRs)...
Water, Vol. 12, Pages 2592: Evaluation of Drought Stress in Cereal through Probabilistic Modelling of Soil Moisture Dynamics Water doi: 10.3390/w12092592 Authors: María del Pilar Jiménez-Donaire Juan Vicente Giráldez Tom Vanwalleghem The early and accurate detection of drought episodes is crucial for managing agricultural yield losses and planning adequate policy responses. This study aimed to evaluate the potential of two novel indices, static and dynamic plant water stress, for...
Water, Vol. 12, Pages 2593: Development of a Model for Stormwater Runoff Prediction on Vertical Test Panels Coated with Plaster and Mortar Water doi: 10.3390/w12092593 Authors: Pablo Vega-Garcia Regina Schwerd Christian Scherer Christoph Schwitalla Brigitte Helmreich Leaching outdoor tests (LOT) are commonly used to assess the leaching of substances from construction materials. In this context, the amount of stormwater in contact with the surface material is of special interest...
Diagnostics, Vol. 10, Pages 700: Influence of 99m-Tc-Nanocolloid Activity Concentration on Sentinel Lymph Node Detection in Endometrial Cancer: A Quantitative SPECT/CT Study Diagnostics doi: 10.3390/diagnostics10090700 Authors: Samine Sahbai Francesco Fiz Florin Taran Sara Brucker Diethelm Wallwiener Juergen Kupferschlaeger Christian La Fougère Helmut Dittmann This study evaluates quantitative combined single photon emission tomography/computed x-ray tomography (SPECT/CT)...
Diagnostics, Vol. 10, Pages 701: Sepsis Diagnostics: Intensive Care Scoring Systems Superior to MicroRNA Biomarker Testing Diagnostics doi: 10.3390/diagnostics10090701 Authors: Fabian Link Knut Krohn Anna-Maria Burgdorff Annett Christel Julia Schumann Sepsis represents a serious medical problem accounting for numerous deaths of critically ill patients in intensive care units (ICUs). An early, sensitive, and specific diagnosis is considered a key element for improving the...
Diagnostics, Vol. 10, Pages 702: Automatic Prediction and Assessment of Treatment Response in Patients with Hodgkin’s Lymphoma Using a Whole-Body DW-MRI Based Approach Diagnostics doi: 10.3390/diagnostics10090702 Authors: Valentina Brancato Marco Aiello Roberta Della Pepa Luca Basso Nunzia Garbino Emanuele Nicolai Marco Picardi Marco Salvatore Carlo Cavaliere The lack of validation and standardization represents the main drawback for a clear role of whole-body...
Diagnostics, Vol. 10, Pages 699: Association of Bone Mineral Density and Coronary Artery Calcification in Patients with Osteopenia and Osteoporosis Diagnostics doi: 10.3390/diagnostics10090699 Authors: Tzyy-Ling Chuang Malcolm Koo Yuh-Feng Wang The aim of this study was to investigate the association between bone mineral density (BMD) and coronary artery calcification (CAC) in adults with osteopenia or osteoporosis. A retrospective medical review study was conducted in a regional...
Pharmaceutics, Vol. 12, Pages 880: Drugs Modulating CD4+ T Cells Blood–Brain Barrier Interaction in Alzheimer’s Disease Pharmaceutics doi: 10.3390/pharmaceutics12090880 Authors: Kubick Flournoy Enciu Manda Mickael : The effect of Alzheimer’s disease (AD) medications on CD4+ T cells homing has not been thoroughly investigated. CD4+ T cells could both exacerbate and reduce AD symptoms based on their infiltrating subpopulations. Proinflammatory subpopulations...
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