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Τετάρτη 16 Σεπτεμβρίου 2020

  HER2-positive human breast carcinoma SK-BR-3 cells by amygdaline-ZHER2 affibody conjugate.

Related Articles Specific targeting of HER2-positive human breast carcinoma SK-BR-3 cells by amygdaline-ZHER2 affibody conjugate. Mol Biol Rep. 2020 Sep 14;: Authors: Moradipoodeh B, Jamalan M, Zeinali M, Fereidoonnezhad M, Mohammadzadeh G Abstract Amygdalin induces apoptotic death in several carcinoma cells. Affibody is an engineered protein with a high affinity for human epidermal receptor 2 (HER2). We assessed the cytotoxic effects of the...
pubmed: her2-positive breast...
01:53
Male breast cancer: A closer look at patient and tumor characteristics and factors associated with survival.
Related Articles Male breast cancer: A closer look at patient and tumor characteristics and factors associated with survival. Thorac Cancer. 2020 Sep 15;: Authors: Zhao J, Wang B, Zhao J, Mao Y, Liu J, Yang Y Abstract BACKGROUND: The prognostic effect of molecular subtypes on male breast cancer (MBC) remains unclear. The aim of this study was to evaluate the clinicopathological and prognostic factors of MBC patients. METHODS: From 1...
pubmed: her2-positive breast...
01:53
Zinc distribution within breast cancer tissue of different intrinsic subtypes.
Related Articles Zinc distribution within breast cancer tissue of different intrinsic subtypes. Arch Gynecol Obstet. 2020 Sep 15;: Authors: Rusch P, Hirner AV, Schmitz O, Kimmig R, Hoffmann O, Diel M Abstract PURPOSE: To show feasibility of laser ablation inductively coupled mass spectrometry (LA-ICPMS) for analysis of zinc content and concentration in breast cancer tissue and to correlate this with validated prognostic and predictive markers,...
pubmed: her2-positive breast...
01:53
Impact of adjuvant trastuzumab on locoregional failure rates in a randomized clinical trial: North Central Cancer Treatment Group N9831 (alliance) study.
Related Articles Impact of adjuvant trastuzumab on locoregional failure rates in a randomized clinical trial: North Central Cancer Treatment Group N9831 (alliance) study. Cancer. 2020 Sep 15;: Authors: Vargas CE, Thorpe CS, Dueck AC, Tenner KS, Davidson NE, Martino S, Pisansky TM, Hwang ES, Halyard MY, Pockaj BA, Perez EA Abstract BACKGROUND: The goal of this study was to assess the impact of trastuzumab on locoregional failure. METHODS:...
pubmed: her2-positive breast...
01:53
Issue Information
Journal of Sleep Research
Sat Sep 12, 2020 15:31
Focus on sleep, insomnia and mental health
Journal of Sleep Research
Sat Sep 12, 2020 15:31
"BMJ Open"[jour]; +27 new citations
27 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: "BMJ Open"[jour] These pubmed results were generated on 2020/09/16PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
pubmed: "bmj open"[jour]
02:05
Afatinib for the first-line treatment of EGFR mutation-positive NSCLC in China: a review of clinical data.
Related Articles Afatinib for the first-line treatment of EGFR mutation-positive NSCLC in China: a review of clinical data. Future Oncol. 2020 Sep 15;: Authors: Tu HY, Wu YL Abstract Mutations in the EGFR gene are particularly prevalent among Chinese patients with non-small-cell lung carcinoma. Six EGFR tyrosine kinase inhibitors are approved for the first-line treatment of EGFR mutation-positive non-small-cell lung carcinoma in China, which...
Future Oncology.
02:06
Development of the Decannulation Prediction Tool in Patients With Dysphagia After Acquired Brain Injury.
Related Articles Development of the Decannulation Prediction Tool in Patients With Dysphagia After Acquired Brain Injury. J Am Med Dir Assoc. 2019 04;20(4):470-475.e1 Authors: Reverberi C, Lombardi F, Lusuardi M, Pratesi A, Di Bari M Abstract OBJECTIVES: Patients with acquired brain injuries (ABIs) often need tracheostomy because of dysphagia. However, many of them may recover over time and be eventually decannulated during post-acute rehabilitation....
Dysphagia - Rehabilitation
02:09
Comprehensive Tool to Assess Oral Feeding Support for Functional Recovery in Post-acute Rehabilitation.
Related Articles Comprehensive Tool to Assess Oral Feeding Support for Functional Recovery in Post-acute Rehabilitation. J Am Med Dir Assoc. 2019 04;20(4):426-431 Authors: Waza M, Maeda K, Katsuragawa C, Sugita A, Tanaka R, Ohtsuka A, Matsui T, Kitagawa K, Kishimoto T, Fukui H, Kawai K, Yamamoto M, Isono M Abstract OBJECTIVE: To determine the influence of the Kuchi-kara Taberu (KT) index on rehabilitation outcomes during hospitalized convalescent...
Dysphagia - Rehabilitation
02:09
Trajectory of change in the swallowing status in spinal muscular atrophy type I.
Related Articles Trajectory of change in the swallowing status in spinal muscular atrophy type I. Int J Pediatr Otorhinolaryngol. 2020 Mar;130:109818 Authors: Choi YA, Suh DI, Chae JH, Shin HI Abstract OBJECTIVES: This study aimed to elucidate the change in progressive swallowing dysfunction from birth up to 2 years of age to provide clinical insights into the management of swallowing difficulty in patients with spinal muscular atrophy (SMA)...
Dysphagia - Rehabilitation
02:09
Effects of blocking mGluR5 on primate dorsolateral prefrontal cortical neuronal firing and working memory performance
Abstract Rationale Metabotropic glutamate type 5 receptor (mGluR5) antagonists are under development for treating cognitive disorders such as Fragile X syndrome and Alzheimer’s disease, largely based on success in mouse models, where post-synaptic mGluR5 stimulation weakens synaptic functions in hippocampus. However, human trials of mGluR5 antagonists have yet to be successful. This may be due in part to the differing effects of mGluR5...
Latest Results for Psychopharmacology
Wed Sep 16, 2020 03:00
TLR4/AP-1-Targeted Anti-Inflammatory Intervention Attenuates Insulin Sensitivity and Liver Steatosis
Insulin resistance has been shown to be the common pathogenesis of many metabolic diseases. Metainflammation is one of the important characteristics of insulin resistance. Macrophage polarization mediates the production and development of metainflammation. Toll-like receptor 4 (TLR4) mediates macrophage activity and is probably the intersection of immunity and metabolism, but the detailed mechanism is probably not fully understood. Activated protein 1 (AP1) signaling pathway is very important in...
Mediators of Inflammation
Wed Sep 16, 2020 16:35
Ligand- and Structure-Based Approaches of Escherichia coli FabI Inhibition by Triclosan Derivatives: From Chemical Similarity to Protein Dynamics Influence.
Related Articles Ligand- and Structure-Based Approaches of Escherichia coli FabI Inhibition by Triclosan Derivatives: From Chemical Similarity to Protein Dynamics Influence. ChemMedChem. 2019 12 04;14(23):1995-2004 Authors: Kronenberger T, de Oliveira Fernades P, Drumond Franco I, Poso A, Gonçalves Maltarollo V Abstract Enoyl-acyl carrier protein reductase (FabI) is the limiting step to complete the elongation cycle in type II fatty acid synthase...
Oncology
02:18
A Modern Approach to Endometrial Carcinoma: Will Molecular Classification Improve Precision Medicine in the Future?
Related Articles A Modern Approach to Endometrial Carcinoma: Will Molecular Classification Improve Precision Medicine in the Future? Cancers (Basel). 2020 Sep 10;12(9): Authors: Marnitz S, Walter T, Schömig-Markiefka B, Engler T, Kommoss S, Brucker SY Abstract Endometrial cancer has been histologically classified as either an estrogen-dependent cancer with a favorable outcome or an estrogen-independent cancer with a worse prognosis. These parameters,...
Oncology
02:18
Natural antisense transcripts in the biological hallmarks of cancer: powerful regulators hidden in the dark.
Related Articles Natural antisense transcripts in the biological hallmarks of cancer: powerful regulators hidden in the dark. J Exp Clin Cancer Res. 2020 Sep 14;39(1):187 Authors: Zhao S, Zhang X, Chen S, Zhang S Abstract Natural antisense transcripts (NATs), which are transcribed from opposite strands of DNA with partial or complete overlap, affect multiple stages of gene expression, from epigenetic to post-translational modifications. NATs...
Oncology
02:18
A Survey-Based Needs Assessment of Barriers to Optimal Sickle Cell Disease Care in the Emergency Department.
Related Articles A Survey-Based Needs Assessment of Barriers to Optimal Sickle Cell Disease Care in the Emergency Department. Ann Emerg Med. 2020 Sep;76(3S):S64-S72 Authors: Linton EA, Goodin DA, Hankins JS, Kanter J, Preiss L, Simon J, Souffront K, Tanabe P, Gibson R, Hsu LL, King A, Richardsona LD, Glassberg JA, Sickle Cell Disease Implementation Consortium Abstract STUDY OBJECTIVE: Guided by an implementation science framework, this needs...
Oncology
02:18
The new world of poly-(ADP)-ribose polymerase inhibitors (PARPi) used in the treatment of gynecological cancers.
Related Articles The new world of poly-(ADP)-ribose polymerase inhibitors (PARPi) used in the treatment of gynecological cancers. Int J Gynecol Cancer. 2020 Sep 14;: Authors: Chelariu-Raicu A, Zibetti Dal Molin G, Coleman RL Abstract The clinical development of poly-(ADP)-ribose polymerase inhibitors (PARPi) began with the treatment of ovarian cancer patients harboring BRCA1/2 mutations and continues to be expanded to other gynecological cancers....
Oncology
02:18
Racial and ethnic differences in sarcoma incidence are independent of census-tract socioeconomic status.
Related Articles Racial and ethnic differences in sarcoma incidence are independent of census-tract socioeconomic status. Cancer Epidemiol Biomarkers Prev. 2020 Sep 14;: Authors: Diessner BJ, Weigel BJ, Murugan P, Zhang L, Poynter JN, Spector LG Abstract BACKGROUND: Epidemiological analyses of sarcoma are limited by the heterogeneity and rarity of the disease. Utilizing population-based surveillance data enabled us to evaluate the contribution...
Oncology
02:18
Combined inhibition of JAK2-STAT3 and SMO-GLI1/tGLI1 pathways suppresses breast cancer stem cells, tumor growth, and metastasis.
Related Articles Combined inhibition of JAK2-STAT3 and SMO-GLI1/tGLI1 pathways suppresses breast cancer stem cells, tumor growth, and metastasis. Oncogene. 2020 Sep 14;: Authors: Doheny D, Sirkisoon S, Carpenter RL, Aguayo NR, Regua AT, Anguelov M, Manore SG, Arrigo A, Jalboush SA, Wong GL, Yu Y, Wagner CJ, Chan M, Ruiz J, Thomas A, Strowd R, Lin J, Lo HW Abstract Triple-negative breast cancer (TNBC) and HER2-positive breast cancer are particularly...
Oncology
02:18
Current methods in translational cancer research.
Related Articles Current methods in translational cancer research. Cancer Metastasis Rev. 2020 Sep 14;: Authors: Lee MW, Miljanic M, Triplett T, Ramirez C, Aung KL, Eckhardt SG, Capasso A Abstract Recent developments in pre-clinical screening tools, that more reliably predict the clinical effects and adverse events of candidate therapeutic agents, has ushered in a new era of drug development and screening. However, given the rapid pace with...
Oncology
02:18
Do tumor exosome integrins alone determine organotropic metastasis?
Related Articles Do tumor exosome integrins alone determine organotropic metastasis? Mol Biol Rep. 2020 Sep 14;: Authors: Grigoryeva ES, Savelieva OE, Popova NO, Cherdyntseva NV, Perelmuter VM Abstract Metastasis is the most life-threatening event in cancer patients, so the key strategy to treat cancer should be preventing tumor spread. Predicting the site of probable hematogenous metastasis is important for determining the therapeutic algorithm...
Oncology
02:18
Patient selection and risk factors in the changing treatment landscape of metastatic renal cell carcinoma.
Related Articles Patient selection and risk factors in the changing treatment landscape of metastatic renal cell carcinoma. Expert Rev Anticancer Ther. 2020 Sep 15;: Authors: Abdou E, Pedapenki RM, Abouagour M, Zar AR, Anwar E, Elshourbagy D, Al-Shamsi H, Grande E Abstract INTRODUCTION: The approval of combination treatments for metastatic renal cell carcinoma (mRCC) represents a major change in the clinical management of this malignancy. Updated...
Oncology
02:18
Clinical trial design: Past, present, and future in the context of big data and precision medicine.
Related Articles Clinical trial design: Past, present, and future in the context of big data and precision medicine. Cancer. 2020 Sep 15;: Authors: Li A, Bergan RC Abstract Clinical trials are fundamental for advances in cancer treatment. The traditional framework of phase 1 to 3 trials is designed for incremental advances between regimens. However, our ability to understand and treat cancer has evolved with the increase in drugs targeting an...
Oncology
02:18
The Future Liver Remnant : Definition, Evaluation, and Management.
Related Articles The Future Liver Remnant : Definition, Evaluation, and Management. Am Surg. 2020 Sep 15;:3134820951451 Authors: Dixon M, Cruz J, Sarwani N, Gusani N Abstract When considering patients for a major hepatectomy, one must carefully consider the volume of liver to be left behind and if additional procedures are necessary to augment its volume. This review considers the optimal volume of the future liver remnant (FLR) and analyzes...
Oncology
02:18
COVID-19 in benign hematology: emerging challenges and special considerations for healthcare professionals.
Related Articles COVID-19 in benign hematology: emerging challenges and special considerations for healthcare professionals. Expert Rev Hematol. 2020 Sep 15;:1-12 Authors: Noun P, Ibrahim A, Hodroj MH, Bou-Fakhredin R, Taher AT Abstract INTRODUCTION: Many patients with inherited or acquired benign hematological disorders are at increased risk of developing severe complications from COVID-19. These patients, therefore, require specific advice...
Oncology
02:18
Hydrogel Network Dynamics Regulate Vascular Morphogenesis.
Related Articles Hydrogel Network Dynamics Regulate Vascular Morphogenesis. Cell Stem Cell. 2020 Sep 02;: Authors: Wei Z, Schnellmann R, Pruitt HC, Gerecht S Abstract Matrix dynamics influence how individual cells develop into complex multicellular tissues. Here, we develop hydrogels with identical polymer components but different crosslinking capacities to enable the investigation of mechanisms underlying vascular morphogenesis. We show that...
Oncology
02:18
PIK3CA mutations matter for cancer in dogs.
Related Articles PIK3CA mutations matter for cancer in dogs. Res Vet Sci. 2020 Sep 08;133:39-41 Authors: Kim JH Abstract Cancer is a genetic disease that arises from the accumulation of genetic mutations within a cell. Mutations in PIK3CA gene are frequently observed in human solid cancers, and also appear to occur in canine tumors. Specifically, recurrent somatic PIK3CA variants identified in canine mammary tumors and hemangiosarcomas are comparable...
Oncology
02:18
Onychomadesis following Covid19 infection:Is there a relationship?
Wiley: Dermatologic Therapy: Table of Contents
Wed Sep 16, 2020 13:09
How far have we reached? Perhaps not enough, new avenues are about to be traveled
The Journal of Physiology
Wed Sep 16, 2020 20:27
Performance of ion chromatography to measure picomoles of magnesium in nanoliter samples
Key points An UHPLC method to measure picomole amounts of magnesium has been developed The method is sensitive, specific, accurate and reproducible. The method is suitable to quantify magnesium transport across intact epithelia Abstract Magnesium is involved in many biological processes. Extracellular magnesium homeostasis mainly depends on the renal handling of magnesium, the study of which requires measurement of low concentration of magnesium in renal tubular fluid. We developed a...
The Journal of Physiology
Wed Sep 16, 2020 20:27
Studying t‐tubular functionality in mechanically skinned fibres to understand the mechanism of muscle fatigue
The Journal of Physiology
Wed Sep 16, 2020 20:28
Mitoflash generated at the Qo site of mitochondrial Complex III.
Related Articles Mitoflash generated at the Qo site of mitochondrial Complex III. J Cell Physiol. 2020 Sep 15;: Authors: Gao M, Qin Y, Li A, Wei S, Liu B, Tian X, Gong G Abstract The previous research has shown that mitochondrial flash (mitoflash) genesis are functionally and mechanistically integrated with mitochondrial electron transport chain (ETC) energy metabolism. However, the response of mitoflash to superoxide is not entirely consistent...
pubmed: "j cell physiol"[jou...
02:21
The overview and perspectives of biosensors and Mycobacterium tuberculosis: A systematic review.
Related Articles The overview and perspectives of biosensors and Mycobacterium tuberculosis: A systematic review. J Cell Physiol. 2020 Sep 15;: Authors: Salimiyan Rizi K, Aryan E, Meshkat Z, Ranjbar G, Sankian M, Ghazvini K, Farsiani H, Pourianfar HR, Rezayi M Abstract Tuberculosis (TB) is referred to as a "consumption" or phthisis, which has been a fatal human disease for thousands of years. Mycobacterium tuberculosis (M. tb) might have been...
pubmed: "j cell physiol"[jou...
02:21
Meta-Analysis of the Association Between the rs228570 Vitamin D Receptor Gene Polymorphism and Arterial Hypertension Risk.
Related Articles Meta-Analysis of the Association Between the rs228570 Vitamin D Receptor Gene Polymorphism and Arterial Hypertension Risk. Adv Nutr. 2020 Sep 01;11(5):1403 Authors: PMID: 32929445 [PubMed - in process]
pubmed: "adv nutr"[jour]
02:26
Reply to M Amiri et al.
Related Articles Reply to M Amiri et al. Adv Nutr. 2020 Sep 01;11(5):1400-1401 Authors: Rahimlou M, Banaie Jahromi N, Hasanyani N, Ramezani Ahmadi A PMID: 32929446 [PubMed - in process]
pubmed: "adv nutr"[jour]
02:26
Comment on "Effects of Flaxseed Interventions on Circulating Inflammatory Biomarkers: A Systematic Review and Meta-Analysis of Randomized Controlled Trials".
Related Articles Comment on "Effects of Flaxseed Interventions on Circulating Inflammatory Biomarkers: A Systematic Review and Meta-Analysis of Randomized Controlled Trials". Adv Nutr. 2020 Sep 01;11(5):1399-1400 Authors: Amiri M, Raeisi-Dehkordi H, Salehi-Abargouei A PMID: 32929447 [PubMed - in process]
pubmed: "adv nutr"[jour]
02:26
Reply to M-L Puhlmann and WM de Vos.
Related Articles Reply to M-L Puhlmann and WM de Vos. Adv Nutr. 2020 Sep 01;11(5):1401-1402 Authors: Araj-Khodaei M, Ghazi-Sha'rbaf J, Taheri-Targhi S, Mohammadinasab R PMID: 32929448 [PubMed - in process]
pubmed: "adv nutr"[jour]
02:26
Energetic and thermodynamical aspects of the cyclodextrins-cannabidiol complex in aqueous solution: a molecular-dynamics study
Abstract Cyclodextrins (CDs) are well-known carriers for encapsulating hydrophobic molecules, while among cannabinoids, cannabidiol (CBD) has attracted considerable attention due to its therapeutic capability. In this framework, we employed molecular dynamics and docking techniques for investigating the interaction energy and thermodynamical issues between different CDs (α, β, and γ type) and CBD immersed in water and a solution mimicking a physiological environment. We quantified...
Latest Results for European Biophysics Journal
Wed Sep 16, 2020 03:00
Carbon‐Ion Radiation Therapy for Sinonasal Malignancies: Promising Results of 2, 282 Cases from The Real World
Summary To compare the effectiveness of carbon‐ion radiation therapy (CIRT), proton radiation therapy (PRT) and photon‐based intensity‐modulated radiation therapy (IMRT) in the treatment of sinonasal malignancies. We identified studies through systematic review and divided into three cohorts (CIRT group/PRT group/IMRT group). Primary outcomes of interest were overall survival (OS) and local control (LC). We pooled the outcomes with meta‐analysis and compared the survival difference among groups...
Cancer Science
Wed Sep 16, 2020 21:01
Facelift Surgery: History, Anatomy, and Recent Innovations
Facial Plast SurgDOI: 10.1055/s-0040-1715616Facelift surgery has become a beautifully predictable, safe, and extremely effective operation. Our patients can expect natural and long-lasting results as a direct outcome of our improved understanding and applications of surgical facial anatomy. Rhytidectomy, once an operation of simple well-placed elliptical skin excisions, evolved to include longer skin flaps, skin and platysma flaps with various superficial muscular aponeurotic system (SMAS) manipulations,...
Facial Plastic Surgery
Wed Sep 16, 2020 02:00
Medial Epicanthoplasty: What Works and What Does Not
Facial Plast SurgDOI: 10.1055/s-0040-1715617Blepharoplasty is the most frequently performed cosmetic surgical procedure in Asia. The epicanthal fold, which is common in Asians, is characterized by a curved skin fold that partially hides the caruncle and lacrimal lake. The epicanthal fold may cause weakening of the esthetic appearance after blepharoplasty. It makes the palpebral fissure height narrower and the length shorter horizontally. Blepharoplasty with epicanthoplasty can enhance the esthetic...
Facial Plastic Surgery
Wed Sep 16, 2020 02:00
Delayed Reconstruction with Full-Thickness Skin Grafts Following Defect Size Reduction in Head and Neck Nonmelanoma Skin Cancer
Facial Plast SurgDOI: 10.1055/s-0040-1715619Different treatment modalities have been applied for nonmelanoma skin cancers (NMSCs) of the head and neck area. One of the most important points after surgical treatment is the selection of appropriate reconstruction methods. The aim of this study is to investigate the efficacy and feasibility of the use of both defect size reduction with sutures and secondary healing with delayed reconstruction with full-thickness skin grafts in NMSC patients. In total,...
Facial Plastic Surgery
Wed Sep 16, 2020 02:00
The Importance of Calibration of Projectometers for Intraoperative Rhinoplasty Profile Measurement
Facial Plast SurgDOI: 10.1055/s-0040-1714674Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.Article in Thieme eJournals:Table of contents  |  Full text
Facial Plastic Surgery
Wed Sep 16, 2020 02:00
[Audit on management of seizures in six Swedish hospitals].
Related Articles [Audit on management of seizures in six Swedish hospitals]. Lakartidningen. 2020 04 22;117: Authors: Al-Jashami F, Berglund M, Bergström L, Bäärnhielm M, Eriksson H, Kumlien E, Melin S, Vall V, Zelano J Abstract Six Swedish hospitals (four university hospitals and two regional hospitals) participated in a pan-European quality assurance project regarding acute management of seizures. Three hundred consecutive emergency department...
pubmed: epilepsy treatment
02:34
Determinants of quality of life in adults living with epilepsy.
Related Articles Determinants of quality of life in adults living with epilepsy. Ann Afr Med. 2020 Jul-Sep;19(3):164-169 Authors: Ayanda KA, Sulyman D Abstract Background: Quality of life (QOL) is a vital outcome measure in people living with epilepsy. The aim of this study is to determine the sociodemographic and clinical factors that predict poor QOL in patients with epilepsy. Materials and Methods: This is a descriptive cross-sectional...
pubmed: epilepsy treatment
02:34
Effects of spore powder of ganoderma lucidum on CaSR and apoptosis-related proteins in hippocampus tissue of epilepsy following dementia: A protocol of systematic review.
Related Articles Effects of spore powder of ganoderma lucidum on CaSR and apoptosis-related proteins in hippocampus tissue of epilepsy following dementia: A protocol of systematic review. Medicine (Baltimore). 2020 Aug 14;99(33):e21711 Authors: Qin LH, Wang C, Jiang XX, Song Y, Feng Y, Qin LW, Zhang SP Abstract BACKGROUND: This study will investigate the effects of Spore Powder of Ganoderma Lucidum (SPGL) on CaSR and apoptosis-related proteins...
pubmed: epilepsy treatment
02:34
In vivo assessment of mechanisms underlying the neurovascular basis of postictal amnesia.
Related Articles In vivo assessment of mechanisms underlying the neurovascular basis of postictal amnesia. Sci Rep. 2020 Sep 14;10(1):14992 Authors: Farrell JS, Colangeli R, Dudok B, Wolff MD, Nguyen SL, Jackson J, Dickson CT, Soltesz I, Teskey GC Abstract Long-lasting confusion and memory difficulties during the postictal state remain a major unmet problem in epilepsy that lacks pathophysiological explanation and treatment. We previously identified...
pubmed: epilepsy treatment
02:34
KA-104, a new multitargeted anticonvulsant with potent antinociceptive activity in preclinical models.
Related Articles KA-104, a new multitargeted anticonvulsant with potent antinociceptive activity in preclinical models. Epilepsia. 2020 Sep 14;: Authors: Kamiński K, Mogilski S, Abram M, Rapacz A, Latacz G, Szulczyk B, Walczak M, Kuś K, Matyjaszczyk K, Kamiński RM Abstract OBJECTIVE: The main objective of the present work was to assess the utility of KA-104 as potential therapy for drug-resistant seizures and neuropathic pain, and to characterize...
pubmed: epilepsy treatment
02:34
[Resistant epileptic encephalopathy in a child with microcephalic capillary malformation syndrome].
Related Articles [Resistant epileptic encephalopathy in a child with microcephalic capillary malformation syndrome]. Zh Nevrol Psikhiatr Im S S Korsakova. 2020;120(8):110-116 Authors: Shchugareva LM, Poteshkina OV, Shumeeva AG, Galaktionova SM Abstract Treatment resistant epileptic encephalopathy (EE) in childhood in a significant amount due to genetic damage or congenital abnormalities of the brain. The literature described a rare microcephalic-capillary...
pubmed: epilepsy treatment
02:34
Cysticercosis and suicide - an example from a forensic collection.
Related Articles Cysticercosis and suicide - an example from a forensic collection. Forensic Sci Med Pathol. 2020 Sep 15;: Authors: Nikolić S, Cvetković D, Živković V Abstract In this case from 1937, the deceased was a 52-year-old female who was suffering from systemic cysticercosis, with prominent neurological and psychiatric symptoms. Given the protracted clinical course and autopsy findings it appears likely that the disease led the woman...
pubmed: epilepsy treatment
02:34
The functional connectivity study on the brainstem-cortical/subcortical structures in responders following cervical vagus nerve stimulation.
Related Articles The functional connectivity study on the brainstem-cortical/subcortical structures in responders following cervical vagus nerve stimulation. Int J Dev Neurosci. 2020 Sep 15;: Authors: Zhu J, Wang J, Xu C, Zhang X, Qiao L, Wang X, Zhang X, Yan X, Ni D, Yu T, Zhang G, Li Y Abstract BACKGROUND: Cervical vagus nerve stimulation (VNS) is an effective neuromodulation therapy for patients with drug-resistant epilepsy (DRE). The previous...
pubmed: epilepsy treatment
02:34
Etiology-related degree of sprouting of parvalbumin-immunoreactive axons in the human dentate gyrus in temporal lobe epilepsy.
Related Articles Etiology-related degree of sprouting of parvalbumin-immunoreactive axons in the human dentate gyrus in temporal lobe epilepsy. Neuroscience. 2020 Sep 12;: Authors: Ábrahám H, Molnár JE, Sóki N, Gyimesi C, Horváth Z, Janszky J, Dóczi T, Seress L Abstract In the present study, we examined parvalbumin-immunoreactive cells and axons in the dentate gyrus of surgically resected tissues of therapy-resistant temporal lobe epilepsy (TLE)...
pubmed: epilepsy treatment
02:34
A 2-point difference of NIHSS as a predictor of acute ischemic stroke outcome at 3 months after thrombolytic therapy.
Related Articles A 2-point difference of NIHSS as a predictor of acute ischemic stroke outcome at 3 months after thrombolytic therapy. Clin Neurol Neurosurg. 2020 Sep 08;198:106206 Authors: Jantasri S, Tiamkao S, Sawanyawisuth K Abstract OBJECTIVE: A good functional response at 24 h from an intravenous recombinant tissue plasminogen activator (rtPA) treatment is associated with 3-month ischemic stroke outcome. The criterion for 24 -h neurological...
pubmed: epilepsy treatment
02:34
human homeostasis; +43 new citations
43 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: human homeostasis These pubmed results were generated on 2020/09/16PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Human homeostasis
02:39
ICAT acts as a Coactivator in Regulating PPARγ Transcriptional Activity in Mesangial Cells
Exp Clin Endocrinol DiabetesDOI: 10.1055/a-0879-1846 Aims Our study aims to explore the role of β-catenin interaction protein-1(ICAT) in regulating peroxisome proliferator-activated receptor γ (PPARγ) transcriptional activity in mesangial cells. The abnormal ICAT expression in mesangial cells under high glucose(HG) contributes to the development of diabetes and its complications such as diabetic...
Experimental and Clinical Endocrinology & Diabetes
Wed Sep 16, 2020 02:00
Active metronomic vinorelbine schedules decrease plasma interleukin-2 levels in mice with Lewis lung carcinoma.
Related Articles Active metronomic vinorelbine schedules decrease plasma interleukin-2 levels in mice with Lewis lung carcinoma. J Chemother. 2020 Sep 15;:1-5 Authors: Orlandi P, Banchi M, Alì G, Di Desidero T, Fini E, Fontanini G, Bocci G Abstract The aim of our study was to investigate the effects of metronomic vinorelbine (mVNR) in a tumor model of Lewis Lung (LL) cancer in immunocompetent C57BL/6 mice, looking at the plasma levels of interleukin-2...
Mediterranean Society of Chemotherapy,http://goo.gl/xg1MRA
02:43
Pathologist‐performed palpation‐guided fine needle aspiration cytology of lingual actinomycosis: A case report and review of literature
Abstract “Lingual actinomycosis” is an uncommon, suppurative inflammation of lingual mucosa, caused by Actinomyces. Infectious oral lesions can mimic benign or malignant neoplasms and fine needle aspiration cytology (FNAC) is a simple, minimally invasive procedure for the assessment of patients with such lesions. Here, we describe the case of a 28‐year old patient presented with an asymptomatic, submucosal nodular mass of the tongue. Then, FNAC was performed by an experienced fine needle aspiration...
Diagnostic Cytopathology
Wed Sep 16, 2020 16:53
An institutional experience: A retrospective analysis of the effect of transitioning from follicular lesion of undetermined significance to atypia of undetermined significance with subclassified atypia on interobserver concordance, rates of neoplasia, and rates of malignancy
Abstract Introduction The rate of malignancy (ROM) in thyroid fine needle aspirations (FNA) classified under “atypia of undetermined significance (AUS)/follicular lesion of undetermined significance (FLUS), including Hürthle cell type (HLUS)” category of The Bethesda system for reporting thyroid cytopathology (TBSRTC) in literature is highly variable. The 2018 TBSRTC was updated to note a preferred categorization of AUS cases into subcategories. This study evaluates the impact of AUS subclassification...
Diagnostic Cytopathology
Wed Sep 16, 2020 16:59
Cytologic features of a case of mixed medullary and follicular cell‐derived thyroid carcinoma with review of the literature
Abstract Mixed medullary and follicular cell‐derived thyroid carcinoma (MMFTC) is a rare primary thyroid carcinoma with morphologic and immunophenotypic evidence of admixed parafollicular and follicular cell‐derived tumor populations within the same tumor. We herein present the fine‐needle aspiration biopsy (FNAB) cytology of a case of MMFTC that was diagnosed histologically and discuss potential clues to the diagnosis for cytologists. We also provide a literature review of this uncommon primary...
Diagnostic Cytopathology
Wed Sep 16, 2020 17:02
Surface expression of MRGPRX2 on resting basophils: An area of controversy
Allergy
Mon Sep 14, 2020 20:50
Dietary diversity and childhood asthma—Dietary acid load, an additional nutritional variable to consider
Allergy
Mon Sep 14, 2020 20:50
Reply to: Dietary diversity and childhood asthma ‐ Dietary acid load, an additional nutritional variable to consider
Allergy
Mon Sep 14, 2020 20:50
Corrigendum
Allergy
Mon Sep 14, 2020 20:50
In This Issue: Graphical Abstracts
Allergy
Mon Sep 14, 2020 20:50
Reply to Sabato V et al “Surface expression of MRGPRX2 expression on resting basophils: An area of controversy”
Allergy
Mon Sep 14, 2020 20:50
Comparing Screening Outcomes for Digital Breast Tomosynthesis and Digital Mammography by Automated Breast Density in a Randomized Controlled Trial: Results from the To-Be Trial.
Related Articles Comparing Screening Outcomes for Digital Breast Tomosynthesis and Digital Mammography by Automated Breast Density in a Randomized Controlled Trial: Results from the To-Be Trial. Radiology. 2020 Sep 15;:201150 Authors: Moshina N, Aase HS, Danielsen AS, Haldorsen IS, Lee CI, Zackrisson S, Hofvind S Abstract Background Digital breast tomosynthesis (DBT) is considered superior to digital mammography (DM) for women with dense...
Radiology
02:48
Diagnostic Algorithm to Differentiate Benign Atypical Leiomyomas from Malignant Uterine Sarcomas with Diffusion-weighted MRI.
Related Articles Diagnostic Algorithm to Differentiate Benign Atypical Leiomyomas from Malignant Uterine Sarcomas with Diffusion-weighted MRI. Radiology. 2020 Sep 15;:191658 Authors: Abdel Wahab C, Jannot AS, Bonaffi PA, Bourillon C, Cornou C, Lefrère-Belda MA, Bats AS, Thomassin-Naggara I, Bellucci A, Reinhold C, Fournier LS Abstract Background Improving the differentiation of uterine sarcomas from atypical leiomyomas remains a clinical...
Radiology
02:48
Brain Iron Assessment after Ferumoxytol-enhanced MRI in Children and Young Adults with Arteriovenous Malformations: A Case-Control Study.
Related Articles Brain Iron Assessment after Ferumoxytol-enhanced MRI in Children and Young Adults with Arteriovenous Malformations: A Case-Control Study. Radiology. 2020 Sep 15;:200378 Authors: Iv M, Ng NN, Nair S, Zhang Y, Lavezo J, Cheshier SH, Holdsworth SJ, Moseley ME, Rosenberg J, Grant GA, Yeom KW Abstract Background Iron oxide nanoparticles are an alternative contrast agent for MRI. Gadolinium deposition has raised safety concerns,...
Radiology
02:48
Improved Interobserver Agreement on Lung-RADS Classification of Solid Nodules Using Semiautomated CT Volumetry.
Related Articles Improved Interobserver Agreement on Lung-RADS Classification of Solid Nodules Using Semiautomated CT Volumetry. Radiology. 2020 Sep 15;:200302 Authors: Gierada DS, Rydzak CE, Zei M, Rhea L Abstract Background Classification of lung cancer screening CT scans depends on measurement of lung nodule size. Information about interobserver agreement is limited. Purpose To assess interobserver agreement in the measurements and American...
Radiology
02:48
MRI of Cerebral Fat Embolism: Type 1 Starfield Pattern.
Related Articles MRI of Cerebral Fat Embolism: Type 1 Starfield Pattern. Radiology. 2020 Sep 15;:202212 Authors: Brun-Vergara ML, Montes D PMID: 32930653 [PubMed - as supplied by publisher]
Radiology
02:48
Table of Content Volume 59, Number 11, November 2020
Genes, Chromosomes and Cancer
Wed Sep 16, 2020 18:44
Photoacoustic endoscopy: a progress review
Abstract Endoscopy has been widely used in biomedical imaging and integrated with various optical and acoustic imaging modalities. Photoacoustic imaging (PAI), one of the fastest growing biomedical imaging modalities, is a non‐invasive and non‐ionizing method that owns rich optical contrast, deep acoustic penetration depth, multi‐scale and multi‐parametric imaging capability. Hence, it is preferred to miniaturize the volume of PAI and develop an emerged endoscopic imaging modality referred to as...
Journal of Biophotonics
Wed Sep 16, 2020 12:29
Nasal Mucosal Brush Biopsy for Cat Allergy
International Forum of Allergy & Rhinology
Wed Sep 16, 2020 14:06
Superior turbinate management and olfactory outcome after endoscopic endonasal transsphenoidal surgery for pituitary adenoma: a propensity score‒matched cohort study
Background Surgical management of the superior turbinate (ST) is required to access the sella in endoscopic endonasal transsphenoidal surgery (EETS) for pituitary adenoma. Two common ST management techniques include partial resection of the ST (PRST) and intentional lateralization of the ST (ILST). Given the concentrated distribution of the olfactory nerve fibers on the medial surface of the ST, in this study we aimed to ascertain whether PRST worsens the objective olfactory outcome when compared...
International Forum of Allergy & Rhinology
Wed Sep 16, 2020 18:38
upper respiratory tract infection; +274 new citations
274 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: upper respiratory tract infection These pubmed results were generated on 2020/09/16PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Upper respiratory tract infection
02:54
Three‐Dimensional Accuracy of Conventional Versus Digital Complete Arch Implant Impressions
Abstract Purpose The accuracy of the digital impressions is still controversial for complete arch implant cases. The aim of this study is to compare the accuracy of different intraoral scanners with the conventional technique in terms of trueness and precision in a complete arch implant model. Material and Methods Eight implants were inserted asymmetrically in a polyurethane edentulous mandibular model with different angulations. A 3‐dimensional (3D) reference model was obtained by scanning...
Journal of Prosthodontics
Wed Sep 16, 2020 12:23
Olfactory disorders in coronavirus disease 2019 patients: a systematic literature review.
Related Articles Olfactory disorders in coronavirus disease 2019 patients: a systematic literature review. J Laryngol Otol. 2020 Sep 15;:1-19 Authors: Fuccillo E, Saibene AM, Canevini MP, Felisati G PMID: 32928323 [PubMed - as supplied by publisher]
The Journal of laryngology and otology http://goo.gl/Tl02xD
03:06
Symbiont‐mediated fly survival is independent of defensive symbiont genotype in the Drosophila melanogaster‐Spiroplasma‐wasp interaction
Abstract When a parasite attacks an insect, the outcome is commonly modulated by the presence of defensive heritable symbionts residing within the insect host. Previous studies noted markedly different strengths of Spiroplasma‐mediated fly survival following attack by the same strain of wasp. One difference between the two studies was the strain of Spiroplasma used. We therefore performed a common garden laboratory experiment to assess whether Spiroplasma‐mediated protection depends upon the strain...
Journal of Evolutionary Biology
Wed Sep 16, 2020 12:20
Genetic and morphological divergence between Littorina fabalis ecotypes in Northern Europe
Abstract Low dispersal marine intertidal species facing strong divergent selective pressures associated with steep environmental gradients have a great potential to inform us about local adaptation and reproductive isolation. Among these, gastropods of the genus Littorina offer a unique system to study parallel phenotypic divergence resulting from adaptation to different habitats related with wave‐exposure. In this study, we focused on two Littorina fabalis ecotypes from Northern European shores...
Journal of Evolutionary Biology
Wed Sep 16, 2020 22:30
Cover image
The cover image is based on the Original Article High‐risk lymph node ratio predicts worse prognosis in patients with locally advanced oral cancer by Tong‐Chao Zhao et al., https://doi.org/10.1111/jop.13043.
Oral Pathology & Medicine
Wed Sep 16, 2020 13:44
Assessing sleep-wake survival dynamics in relation to sleep quality in a placebo-controlled pharmacological intervention study with people with insomnia and healthy controls
Abstract Rationale The mechanisms underlying impaired sleep quality in insomnia are not fully known, but an important role for sleep fragmentation has been proposed. Objectives The aim of this study is to explore potential mechanisms of sleep fragmentation influencing alterations of perceived sleep quality. ...
Latest Results for Psychopharmacology
03:00
Activation of PKC induces leukocyte adhesion by the dephosphorylation of ERM.
Related Articles Activation of PKC induces leukocyte adhesion by the dephosphorylation of ERM. Biochem Biophys Res Commun. 2020 02 26;523(1):177-182 Authors: Tachibana K, Ohnishi H, Ali Haghparast SM, Kihara T, Miyake J Abstract Although circulating leukocytes are non-adherent cells, they also undergo adhesion in response to external stimuli. To elucidate this switch mechanism, we investigated PMA-induced cell adhesion in myelomonocytic KG-1 cells....
Technologies in Treatment of Head & Neck
03:09
Implantation of a new active bone conduction hearing device with optimized geometry.
Related Articles Implantation of a new active bone conduction hearing device with optimized geometry. HNO. 2020 Aug;68(Suppl 2):106-115 Authors: Plontke SK, Götze G, Wenzel C, Rahne T, Mlynski R Abstract Here, we describe the surgical technique for implanting a new, active, transcutaneous bone conduction hearing aid. The implant technology is based on a system that has been in use reliably since 2012. The geometry of the new implant has been...
Technologies in Treatment of Head & Neck
03:09
Integrative genomic analysis of salivary duct carcinoma.
Related Articles Integrative genomic analysis of salivary duct carcinoma. Sci Rep. 2020 Sep 14;10(1):14995 Authors: Kim Y, Song S, Lee M, Swatloski T, Kang JH, Ko YH, Park WY, Jeong HS, Park K Abstract Salivary duct carcinoma (SDC) is one of the most aggressive subtypes of salivary gland cancers. Conventional chemotherapy and/or radiation have shown only limited clinical efficacy in the treatment of recurrent or metastatic SDC. Currently, clinically...
Technologies in Treatment of Head & Neck
03:09
Establishment of patient-derived cancer organoids for drug-screening applications.
Related Articles Establishment of patient-derived cancer organoids for drug-screening applications. Nat Protoc. 2020 Sep 14;: Authors: Driehuis E, Kretzschmar K, Clevers H Abstract Adult stem cell-based organoid technology is a versatile tool for the generation and long-term maintenance of near-native 3D epithelial tissues in vitro. The generation of cancer organoids from primary patient material enables a range of therapeutic agents to be tested...
Technologies in Treatment of Head & Neck
03:09
Evaluation of the auricular surface method for subadult sex estimation on Italian modern (19th to 20th century) identified skeletal collections
Metric sex assessment through examination of auricular surface in subadults Abstract Objectives Sex estimation in subadult skeletal remains is still considered highly problematic. The aim of this research is to test the reliability of the method of subadult sex assessment proposed by Luna and co‐workers in 2017, based on the analysis of the auricular surface of the ilium. Materials and Methods Seven ratios and three morphological traits were recorded for 127 subadult individuals...
American Journal of Physical Anthropology
Wed Sep 16, 2020 11:04
Berbers and Arabs: Tracing the genetic diversity and history of Southern Tunisia through genome wide analysis
Abstract Objectives Tunisia has been a crossroads for people from Africa, Europe, and the Middle East since prehistoric times. At present, it is inhabited by two main ethnic groups, Arabs and Berbers, and several minorities. This study aims to advance knowledge regarding their genetic structure using new population samplings and a genome‐wide approach. Materials and Methods We investigated genomic variation, estimated ancestry components and dated admixture events in three Berber and two...
American Journal of Physical Anthropology
Wed Sep 16, 2020 11:08
Leveraging genetic ancestry to study health disparities
Abstract Research to understand human genomic variation and its implications in health has great potential to contribute in the reduction of health disparities. Biological anthropology can play important roles in genomics and health disparities research using a biocultural approach. This paper argues that racial/ethnic categories should not be used as a surrogate for sociocultural factors or global genomic clusters in biomedical research or clinical settings, because of the high genetic heterogeneity...
American Journal of Physical Anthropology
Wed Sep 16, 2020 12:29
Troubles in Tuva: Patterns of perimortem trauma in a nomadic community from Southern Siberia (second to fourth c. CE)
Abstract Objectives Warfare is assumed to be one of the defining cultural characteristics of steppe nomads in Eastern Eurasia. For the first‐centuries CE, a period of political turmoil in Northern China and Southern Siberia, relatively few data are, however, available about the degree and variability of violence in these communities. Here, we provide new data on violence among steppe nomads during the first‐centuries CE by analyzing the type, anatomical distribution, and demographic distribution...
American Journal of Physical Anthropology
Wed Sep 16, 2020 13:01
A caustic ingestion consequence mistaken for gastric cancer: A case report.
Related Articles A caustic ingestion consequence mistaken for gastric cancer: A case report. Int J Surg Case Rep. 2020 Sep 08;75:100-103 Authors: El-Helou E, Alimoradi M, Sabra H, Naccour J, Haddad MM, Bitar H Abstract INTRODUCTION: This report is a case of a suicide attempt by bleach ingestion. mistaken for gastric cancer after oral contrast studies and esophagogastroduodenoscopy. We report this case to encourage physicians to take this etiology...
pubmed: "int j surg case rep...
03:17
Respiratory roller coaster ride following ambulatory surgery in a young woman: A case report.
Related Articles Respiratory roller coaster ride following ambulatory surgery in a young woman: A case report. Int J Surg Case Rep. 2020 Sep 06;75:104-107 Authors: Liu Y, Zhu X, Xie Y, Yan J, Guo Q Abstract INTRODUCTION: Ambulatory surgery has the advantages of shortening the waiting time for hospitalization and reducing medical expenses. It has been more and more widely used in recent years in China. The patients admitted in Ambulatory Surgery...
pubmed: "int j surg case rep...
03:17
Embryonal mastoid rhabdomyosarcoma in a three years old child: A case report.
Related Articles Embryonal mastoid rhabdomyosarcoma in a three years old child: A case report. Int J Surg Case Rep. 2020 Sep 03;75:108-111 Authors: Beghdad M, Mkhatri A, Berrada O, Abada R, Mahtar M Abstract INTRODUCTION: Rhabdomyosarcoma is the most common malignant soft tissue tumor in the pediatric age, especially in the head and neck region; in the orbit and the nasopharynx. The middle ear is a very rare site for this neoplasm as it accounts...
pubmed: "int j surg case rep...
03:17
Dual mobility acetabular construct with freedom constrained liner for treatment of recurrent dislocations after total hip arthroplasty: A case report and literature review.
Related Articles Dual mobility acetabular construct with freedom constrained liner for treatment of recurrent dislocations after total hip arthroplasty: A case report and literature review. Int J Surg Case Rep. 2020 Sep 08;75:94-99 Authors: Onochi Y, Fukui K, Kaneuji A, Ichiseki T, Wang X, Kawahara N Abstract INTRODUCTION: Recurrent dislocation after total hip arthroplasty (THA) using the dual mobility cup system can present challenges, while...
pubmed: "int j surg case rep...
03:17
Metaplastic breast cancers frequently express immune checkpoint markers FOXP3 and PD-L1
Cancer
03:00
Prognostic and predictive significance of nuclear HIF1α expression in locally advanced HNSCC patients treated with chemoradiation with or without nimotuzumab
Cancer
03:00
Breast cancer survival in Nordic <i>BRCA2</i> mutation carriers—unconventional association with oestrogen receptor status
Cancer
03:00
Relationship of leukaemias with long-term ambient air pollution exposures in the adult Danish population
Cancer
03:00
Management of Graves'Thyroidal And Extrathyroidal Disease - An Update.
Related Articles Management of Graves'Thyroidal And Extrathyroidal Disease - An Update. J Clin Endocrinol Metab. 2020 Sep 14;: Authors: Kahaly GJ Abstract CONTEXT: Invited update on the management of systemic autoimmune Graves 'disease (GD) and associated orbitopathy (GO). EVIDENCE ACQUISITION: Guidelines, pertinent original articles, systemic reviews, and meta-analyses. EVIDENCE SYNTHESIS: Thyrotropin receptor antibodies...
radioactive iodine
03:19
Masthead
The Laryngoscope
Fri Sep 11, 2020 21:58
Table of contents
The Laryngoscope
Fri Sep 11, 2020 21:58
Tolerance of Continuous Positive Airway Pressure After Sinonasal Surgery
Objectives/Hypothesis For patients with obstructive sleep apnea (OSA) undergoing sinonasal surgery, there is a lack of consensus on the risk and appropriate postoperative use of continuous positive airway pressure (CPAP). The aim of this study was to assess the tolerability of restarting CPAP on postoperative day one. Study Design Prospective cohort study. Methods A prospective study on patients with OSA on CPAP who required a septoplasty/turbinectomy and/or functional endoscopic sinus...
The Laryngoscope
Wed Sep 16, 2020 21:01
human physiology; +114 new citations
114 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: human physiology These pubmed results were generated on 2020/09/16PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Human physiology
03:22
Important Pharmacogenetic Information for Drugs Prescribed During the SARS‐CoV‐2 Infection (COVID‐19)
In December 2019, the severe acute respiratory syndrome virus‐2 pandemic began, causing the coronavirus disease 2019. A vast variety of drugs is being used off‐label as potential therapies. Many of the repurposed drugs have clinical pharmacogenetic guidelines available with therapeutic recommendations when prescribed as indicated on the drug label. The aim of this review is to provide a comprehensive summary of pharmacogenetic biomarkers available for these drugs, which may help to prescribe them...
Clinical and Translational Science
Wed Sep 16, 2020 16:40
Accurate determination of node and arc multiplicities in de bruijn graphs using conditional random fields.
Related Articles Accurate determination of node and arc multiplicities in de bruijn graphs using conditional random fields. BMC Bioinformatics. 2020 Sep 14;21(1):402 Authors: Steyaert A, Audenaert P, Fostier J Abstract BACKGROUND: De Bruijn graphs are key data structures for the analysis of next-generation sequencing data. They efficiently represent the overlap between reads and hence, also the underlying genome sequence. However, sequencing...
pubmed: "bmc bioinformatics"...
03:25
Perceptions of key informants on the provision of cervical cancer prevention and control programme in Uganda: implication for cervical cancer policy.
Related Articles Perceptions of key informants on the provision of cervical cancer prevention and control programme in Uganda: implication for cervical cancer policy. BMC Public Health. 2020 Sep 14;20(1):1396 Authors: Obol JH, Harrison R, Lin S, Obwolo MJ, Richmond R Abstract BACKGROUND: Uganda has one of the highest burdens of cervical cancer globally. In 2010 the Ugandan Ministry of Health launched the Strategic Plan for Cervical Cancer Prevention...
pubmed: "bmc public health"[...
03:25
Are sedentary behavior and physical activity independently associated with cardiometabolic benefits? The Hispanic Community Health Study/Study of Latinos.
Related Articles Are sedentary behavior and physical activity independently associated with cardiometabolic benefits? The Hispanic Community Health Study/Study of Latinos. BMC Public Health. 2020 Sep 14;20(1):1400 Authors: Mossavar-Rahmani Y, Hua S, Qi Q, Strizich G, Sotres-Alvarez D, Talavera GA, Evenson KR, Gellman MD, Stoutenberg M, Castañeda SF, Gallo LC, Perreira KM, Sanchez-Johnsen LAP, Kaplan RC Abstract BACKGROUND: Whether physical activity...
pubmed: "bmc public health"[...
03:25
Effect of football activity and physical fitness on information processing, inhibitory control and working memory in adolescents.
Related Articles Effect of football activity and physical fitness on information processing, inhibitory control and working memory in adolescents. BMC Public Health. 2020 Sep 14;20(1):1398 Authors: Williams RA, Cooper SB, Dring KJ, Hatch L, Morris JG, Sunderland C, Nevill ME Abstract BACKGROUND: Whilst an acute bout of exercise has been shown to enhance subsequent cognition, including in adolescents, the effects of team games (of which Football...
pubmed: "bmc public health"[...
03:25
Association between long-term exposure to air pollutants and cardiopulmonary mortality rates in South Korea.
Related Articles Association between long-term exposure to air pollutants and cardiopulmonary mortality rates in South Korea. BMC Public Health. 2020 Sep 14;20(1):1402 Authors: Hwang J, Kwon J, Yi H, Bae HJ, Jang M, Kim N Abstract BACKGROUND: The association between long-term exposure to air pollutants, including nitrogen dioxide (NO2), carbon monoxide (CO), sulfur dioxide (SO2), ozone (O3), and particulate matter 10 μm or less in diameter (PM10),...
pubmed: "bmc public health"[...
03:25
Family SES, family social capital, and general health in Chinese adults: exploring their relationships and the gender-based differences.
Related Articles Family SES, family social capital, and general health in Chinese adults: exploring their relationships and the gender-based differences. BMC Public Health. 2020 Sep 14;20(1):1401 Authors: Ji Y, Yun Q, Jiang X, Chang C Abstract BACKGROUND: Numerous studies have clarified that family socioeconomic status (SES) is positively associated with health. However, the mechanism of family SES on health needs to be further investigated...
pubmed: "bmc public health"[...
03:25
Knowledge, attitude and practice towards risky sexual behaviors among secondary and preparatory students of Metu town, south western Ethiopia.
Related Articles Knowledge, attitude and practice towards risky sexual behaviors among secondary and preparatory students of Metu town, south western Ethiopia. BMC Public Health. 2020 Sep 14;20(1):1394 Authors: Keto T, Tilahun A, Mamo A Abstract BACKGROUND: Sexual risk behaviors are defined as sexual activities that may make an individual liable to the risk of sexually transmitted infections including Human Immunodeficiency virus (HIV) and unplanned...
pubmed: "bmc public health"[...
03:25
Social diversity and access to healthcare in Europe: how does European Union's legislation prevent from discrimination in healthcare?
Related Articles Social diversity and access to healthcare in Europe: how does European Union's legislation prevent from discrimination in healthcare? BMC Public Health. 2020 Sep 14;20(1):1399 Authors: Orzechowski M, Nowak M, Bielińska K, Chowaniec A, Doričić R, Ramšak M, Łuków P, Muzur A, Zupanič-Slavec Z, Steger F Abstract BACKGROUND: Social diversity can affect healthcare outcomes in situations when access to healthcare is limited for specific...
pubmed: "bmc public health"[...
03:25
Hypertension care cascade in Chile: a serial cross-sectional study of national health surveys 2003-2010-2017.
Related Articles Hypertension care cascade in Chile: a serial cross-sectional study of national health surveys 2003-2010-2017. BMC Public Health. 2020 Sep 14;20(1):1397 Authors: Passi-Solar Á, Margozzini P, Mindell JS, Ruiz M, Valencia-Hernandez CA, Scholes S Abstract BACKGROUND: Trend data on hypertension prevalence and attainment indicators at each step of the care cascade (awareness, treatment, control) are required in Chile. This study aims...
pubmed: "bmc public health"[...
03:25
Psychological correlates of COVID-19 pandemic in the Austrian population.
Related Articles Psychological correlates of COVID-19 pandemic in the Austrian population. BMC Public Health. 2020 Sep 14;20(1):1395 Authors: Traunmüller C, Stefitz R, Gaisbachgrabner K, Schwerdtfeger A Abstract BACKGROUND: COVID-19 poses the greatest challenge for the entire world since the Second World War. Governments are forced to define strict measures to avoid the spreading of the virus, which may further impose psychological burden for...
pubmed: "bmc public health"[...
03:25

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