Underlying Mechanism for Reduced Left Ventricular Mass by Physical Activity in Obese and Hypertensive Subjects

To the Editor: We read with great interest the article by Dr Kamimura et al.¹ dealing with the relationship between physical activity (PA) and left ventricular (LV) mass in obese and hypertensive African Americans. The results of their study demonstrated that, after adjusting for confounding factors, higher PA index was independently associated with lower cardiac LV mass index. In addition, higher PA index was associated with lower LV mass more in obese or hypertensive participants compared with nonobese or nonhypertensive participants. The authors have proposed that higher PA index might be associated with reduced LV hypertrophy in obese and hypertensive African Americans, suggesting that PA could prevent LV hypertrophy and potentially reduce the risk of heart failure.

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