Emergence of various NDM-type metallo-{beta}-lactamase-producing Escherichia coli clinical isolates in Nepal [PublishAheadOfPrint]

Of 250 clinical isolates of Escherichia coli obtained in Nepal, 38 were carbapenem-resistant with MICs ≥4 μg/ml to imipenem or meropenem. All 38 isolates harbored bla_NDMs: bla_NDM-1, bla_NDM-3, bla_NDM-4, bla_NDM-5, bla_NDM-7, bla_NDM-12 and bla_NDM-13. Most of these isolates also harbored the 16S rRNA methylase gene(s) armA, rmtB and/or rmtC.

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