Issue Highlights

Although anti-thrombotic agents are a known risk factor for upper gastrointestinal (GI) bleeding, their impact on patient outcomes is unclear. In this issue of Clinical Gastroenterology and Hepatology, Dunne and colleagues1 reported results from a multi-center, multi-national prospective cohort study to assess the effect of anti-thrombotic agents on outcomes in patients with high-risk upper GI bleeding. The authors evaluated 568 patients with acute upper GI bleeding who underwent endoscopy between March 2014 and March 2015, of whom 44% used anti-thrombotic agents.

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