Functional Gastrointestinal Symptoms in Inflammatory Bowel Disease: Rising to the Challenge

We read the recent article by Colombel et al1 with interest. We applaud the authors for drawing attention to the plight of patients with inflammatory bowel disease (IBD) who report ongoing symptoms in the absence of inflammation. Recently, the inflammatory bowel South-Eastern Norway study has highlighted that, even among patients with ulcerative colitis (UC) in deep histological remission, 1 in 3 may report these so-called functional symptoms.2 Whether such symptoms are due to genuine coexisting functional disease3 or not, they have a substantial impact on the quality of life and psychological health of patients.

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