Transvenous Renal Biopsy of Critically Ill Patients: Safety and Diagnostic Yield

Objectives: Transvenous renal biopsy is an alternative way to obtain kidney samples from patients with bleeding risk factors (e.g., antiplatelet therapy and anticoagulation or coagulation disorders). This study was undertaken to determine the safety and diagnostic yield of transvenous renal biopsy of critically ill patients. Design: Monocenter, retrospective, observational cohort study. Setting: A 26-bed French tertiary ICU. Patients: All patients undergoing in-ICU transvenous renal biopsy between January 2002 and February 2018. Interventions: None. Measurements and Main Results: Eighty patients (male/female sex ratio, 0.95; mean ± SD age, 47.3 ± 18.3 yr) were included. A histologic diagnosis was obtained for 77 patients (96.3%), with acute tubular necrosis being the most frequent: 23 (29.9%). A potentially treatable cause was found for 47 patients (58.7%). The numbers of patients with 0, 1, 2, or 3 factors (i.e., antiplatelet therapy, thrombopenia [

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