Ibrutinib Regimens versus Chemoimmunotherapy in Older Patients with Untreated CLL

Chronic lymphocytic leukemia (CLL) is the most prevalent form of leukemia in adults and is incurable in most cases. Investigation into the pathogenesis of CLL has implicated B-cell receptor signaling as a central driver, and targeting of this pathway through inhibition of Bruton's tyrosine kinase…

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