In Regard to Yang et al

To the Editor: We read with interest the article by Yang et al (1) that reported the pattern of androgen deprivation therapy (ADT) use with radiation therapy (RT) in men with low-risk prostate cancer (PC) in the US National Cancer Database between 2004 and 2012. Overall, they noted 18% of 82,352 men with low-risk PC, who underwent RT as primary treatment, received ADT. The addition of ADT had been shown in a subanalysis in the RTOG (Radiation Therapy Oncology Group) 9408 trial to confer no benefit in men with low-risk PC receiving RT (2).

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