Adaptive Replanning for HPV-Associated N2b Oropharyngeal Squamous Cell Carcinoma in Response to Anatomic Changes During Radiation Therapy

Repeat CT simulation and dosimetric planning in response to weight loss or tumor response takes substantial resources. All published studies are compromised by heterogeneity of the study population, timing of replanning, and dosimetric endpoints. We report the first prospective evaluation of dosimetric changes from replanning at a uniform timepoint in a uniform patient population.

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