Endoscopic submucosal dissection learning curve and role in the treatment of Barrett's neoplasia

We read with interest the articles by Yang et al1 and by Subramaniam et al2 on the role of endoscopic submucosal dissection (ESD) for the treatment of neoplastic Barrett's esophagus (NBE). Conventional multimodal endoscopic treatment has some limitations, such as recurrence of neoplasia and intestinal metaplasia in 4% and 8% of cases, respectively, and adverse events in 19% of patients.3

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