Arsenic Exposure in Incident Hemodialysis Patients

We read with interest the article by Tonelli et al,1 who prospectively examined plasma concentrations of 25 trace elements in 198 incident hemodialysis patients in Canada. Notably, the group reported that some hemodialysis patients have excessive plasma total arsenic concentrations, and the proportion of patients with plasma arsenic concentrations exceeding the 95th percentile was 9.1% to 9.8%. The observation is important, but we believe that dietary intake of organic arsenic compounds should be excluded before any definite conclusions can be drawn.

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