NG-test Carba5 for rapid detection of carbapenemase-producing Enterobacterales from positive blood cultures [Mechanisms of Resistance]

The immunochromatographic assay, NG-test Carba5 (NG-biotech), has been evaluated for detection of carbapenemase-producing Enterobacterales (CPE) from spiked blood cultures (n=205). It detected and discriminated in less than 30 minutes KPC-, IMP-, VIM-, NDM- and OXA-48-like-producers with a sensitivity and specificity of 97.7% and 96.1%. Thus, it might help the rapid optimization of treatment of bloodstream infections due to CPE.

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