A Phase II Clinical Trial of SAbR Followed by Immediate Vertebroplasty for Spine Metastases

This prospective phase II trial was designed to demonstrate an immediate improvement in pain response following SAbR plus immediate vertebroplasty compared to historical controls and to observe whether subsequent late VCF can be avoided. The three month pain response was significantly improved compared to RTOG 9714, 95% vs 51% (p < 0.0001) and the freedom from VCF was 90% at 2 years.

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