Automated EEG source imaging: a retrospective, blinded clinical validation study

Approximately 1/3 of patients with epilepsy are drug-resistant (Kwan et al. 2000). In this patient group, epilepsy surgery of the presumed epileptogenic focus is currently the treatment option with highest efficacy (Dwivedi et al. 2017; Engel et al. 2012; Wiebe et al. 2001). However, accurate localization of the epileptic focus is often challenging. Since there is no single-modality that reliably can localize the area that needs to be resected in order to render the patient seizure-free (EZ, epileptogenic zone), the presurgical evaluation is based on a multimodal approach (Rosenow and Lüders 2001).

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