Immediate Radiation and Chemotherapy

We would recommend immediate adjuvant treatment with radiation and chemotherapy (1). Radiation therapy would be directed to the tumor bed and residual disease as indicated by the T2/fluid-attenuated inversion recovery signal with a 7- to 10-mm margin treated to 54 Gy at 1.8 Gy/fraction with at least sequential and optionally, concurrent temozolomide.

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