Frailty as an Outcome in Geriatrics Research: Not Ready for Prime Time?

Studies suggest that exercise-based interventions may improve physical functioning and prevent disability among frail older adults. This secondary analysis of a large multicenter randomized controlled trial involving sedentary older adults compared the effects of a structured physical activity program versus health education on the risk of frailty. The authors also examined whether the participants' baseline frailty status modified the positive effects of the physical activity intervention on reducing major mobility disability.

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