Movement-related neural processing in people with congenital mirror movements beyond the (cortical) surface

We read with interest the article of Franz and Fu, highlighting the existence of abnormal pre-movement planning processes in subjects with congenital mirror movements (CMM) (Franz and Fu, 2017). By means of an accurate EEG study paradigm, the authors suggested a failure of inhibitory mechanisms at the level of the supplementary and primary motor cortices as a phenomenon associated to CMM in non-syndromic patients. According to the authors, besides a supposed abnormal decussation of the pyramidal cortico-spinal tract, the abnormal control of the pre-movement cortical activity is the key factor in the pathogenesis of CMM.

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