Outcome after Radiotherapy for Langerhans Cell Histiocytosis Is Dependent on Site of Involvement

Langerhans cell histiocytosis is a rare histiocytic malignancy associated with a wide range of clinical presentations and outcomes. We explored treatment patterns and outcomes in a cohort of 39 patients with 46 radiation-treated lesions. We found the rate of local failure was significantly higher in patients with non-bone lesions, especially of the skin and brain, compared to excellent local control in bone lesions with relatively low doses of radiation.

http://ift.tt/2AoIlJO