MR-OPERA – A Multi-center/multi-vendor validation of MRI-only prostate treatment planning using synthetic CT images

This study aimed to validate a commercially available software for MR to synthetic CT conversion for the use in an MRI-only prostate external radiotherapy workflow. A multi-center study design was used to compare CT-based treatment plans to recalculated synthetic CT plans for 170 prostate cancer patients. The software was found to be robust for a variety of field strengths, vendors and treatment techniques.

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