Primary tumor location found to impact prognosis and response to therapy in patients with metastatic colorectal cancer

Key Points

• Patients with mCRC with a left-sided primary tumor carry a better prognosis than patients with tumors originating on the right side.
• Adding cetuximab to chemotherapy improves outcomes for patients with left-sided tumors, but not for those with right-sided ones.
• Side of origin should be considered when deciding on therapeutic regimens for patients with mCRC.

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