Antibiotics, Vol. 9, Pages 483: Identification and Characterization of Quorum-Quenching Activity of N-Acylhomoserine Lactonase from Coagulase-Negative Staphylococci Antibiotics doi: 10.3390/antibiotics9080483 Authors: Tomohiro Morohoshi Yaoki Kamimura Nobutaka Someya N-Acylhomoserine lactones (AHLs) are used as quorum-sensing signals in Gram-negative bacteria. Many genes encoding AHL-degrading enzymes have been cloned and characterized in various microorganisms. Coagulase-negative...
Wed Aug 05, 2020 03:00
Antibiotics, Vol. 9, Pages 482: Mycobacterium szulgai Lung Disease or Breast Cancer Relapse—Case Report Antibiotics doi: 10.3390/antibiotics9080482 Authors: Anna Kempisty Ewa Augustynowicz-Kopec Lucyna Opoka Monika Szturmowicz Cancers are one of the risk factors of non-tuberculous mycobacterial (NTM) lung disease. The majority of data in this group of patients concern infections caused by Mycobacterium avium—the most prevalent NTM species worldwide. In contrast, limited...
Wed Aug 05, 2020 03:00
Antibodies, Vol. 9, Pages 40: Prediction of Clearance of Monoclonal and Polyclonal Antibodies and Non-Antibody Proteins in Children: Application of Allometric Scaling Antibodies doi: 10.3390/antib9030040 Authors: Iftekhar Mahmood Allometric scaling can be used for the extrapolation of pharmacokinetic parameters from adults to children. The objective of this study was to predict clearance of therapeutic proteins (monoclonal and polyclonal antibodies and non-antibody proteins) allometrically...
Wed Aug 05, 2020 03:00
Antibodies, Vol. 9, Pages 41: Solutions to Avoid False Positives for Rituximab in Pre-Transplant Crossmatches Antibodies doi: 10.3390/antib9030041 Authors: Argentina Colmenero Velazquez Ignacio Iturrieta-Zuazo Juan Luis Valdivieso Shephard Marisa Di Natale Claudia Rita Rubén Ballester González José Luis Castañer Alabau Israel Nieto Gañán Rituximab (anti-CD20) is commonly used as immunotherapy against B cells, in the context of pre-transplant crossmatches,...
Wed Aug 05, 2020 03:00
Antibodies, Vol. 9, Pages 39: Optimization of Methods for the Production and Refolding of Biologically Active Disulfide Bond-Rich Antibody Fragments in Microbial Hosts Antibodies doi: 10.3390/antib9030039 Authors: Bhupal Ban Maya Sharma Jagathpala Shetty Antibodies have been used for basic research, clinical diagnostics, and therapeutic applications. Escherichia coli is one of the organisms of choice for the production of recombinant antibodies. Variable antibody genes have canonical...
Wed Aug 05, 2020 03:00
Antioxidants, Vol. 9, Pages 712: Protective Effect of Fenofibrate on Oxidative Stress-Induced Apoptosis in Retinal–Choroidal Vascular Endothelial Cells: Implication for Diabetic Retinopathy Treatment Antioxidants doi: 10.3390/antiox9080712 Authors: Ying-Jung Hsu Chao-Wen Lin Sheng-Li Cho Wei-Shiung Yang Chung-May Yang Chang-Hao Yang Diabetic retinopathy (DR) is an important microvascular complication of diabetes and one of the leading causes of blindness in developed countries....
Wed Aug 05, 2020 03:00
Antioxidants, Vol. 9, Pages 710: Eukarion-134 Attenuates Endoplasmic Reticulum Stress-Induced Mitochondrial Dysfunction in Human Skeletal Muscle Cells Antioxidants doi: 10.3390/antiox9080710 Authors: Anastasia Thoma Max Lyon Nasser Al-Shanti Gareth A. Nye Robert G. Cooper Adam P. Lightfoot Maladaptive endoplasmic reticulum (ER) stress is associated with modified reactive oxygen species (ROS) generation and mitochondrial abnormalities; and is postulated as a potential mechanism...
Wed Aug 05, 2020 03:00
Antioxidants, Vol. 9, Pages 709: The Versatility of Antioxidant Assays in Food Science and Safety—Chemistry, Applications, Strengths, and Limitations Antioxidants doi: 10.3390/antiox9080709 Authors: Nabeelah Bibi Sadeer Domenico Montesano Stefania Albrizio Gokhan Zengin Mohamad Fawzi Mahomoodally Currently, there is a growing interest in screening and quantifying antioxidants from biological samples in the quest for natural and effective antioxidants to combat free radical-related...
Wed Aug 05, 2020 03:00
Antioxidants, Vol. 9, Pages 711: Reduction of Nitrite in Meat Products through the Application of Various Plant-Based Ingredients Antioxidants doi: 10.3390/antiox9080711 Authors: Ferysiuk Wójciak Nitrite is the most commonly applied curing agent in the meat industry, and is known to affect human health. Nitrites impart a better flavor, taste and aroma; preserve the red-pinkish color of the meat; and prevent the risk of bacterial contamination of the cured meat, especially from Clostridium...
Wed Aug 05, 2020 03:00
Atmosphere, Vol. 11, Pages 827: Farmers’ Perceptions of Climate Change and Agricultural Adaptation in Burkina Faso Atmosphere doi: 10.3390/atmos11080827 Authors: Jorge Alvar-Beltrán Abdalla Dao Anna Dalla Marta Ana Heureux Jacob Sanou Simone Orlandini The Sahel region is considered a hotspot for climate change hazards and vulnerability of weather reliant sectors, including agriculture. Farmers in Burkina Faso have a long history of adapting their farming activities to...
Wed Aug 05, 2020 03:00
Atmosphere, Vol. 11, Pages 826: Comparison of Respiratory and Ischemic Heart Mortalities and their Relationship to the Thermal Environment Atmosphere doi: 10.3390/atmos11080826 Authors: Irmela Schlegel Stefan Muthers Hans-Guido Mücke Andreas Matzarakis Chronic respiratory and ischemic heart diseases are globally important parts of total mortality. This study focuses on the occurrence of mortality due to these disease groups in Germany and possible effects of the thermal environment....
Wed Aug 05, 2020 03:00
Atmosphere, Vol. 11, Pages 825: 7Be, 210Pbatm and 137Cs in Snow Deposits in the Arctic Part of Western Siberia (Yamal-Nenets Autonomous District) Atmosphere doi: 10.3390/atmos11080825 Authors: Kseniya Mezina Mikhail Melgunov Dmitriy Belyanin Radioactive isotopes (7Be, 210Pbatm and 137Cs) are used as indicators of processes associated with the transfer of matter from the atmosphere. Studying snow cover can provide information about the seasonal deposition flux of the isotopes to...
Wed Aug 05, 2020 03:00
Atmosphere, Vol. 11, Pages 824: Reconciling Chord Length Distributions and Area Distributions for Fields of Fractal Cumulus Clouds Atmosphere doi: 10.3390/atmos11080824 Authors: Nicholas R. Barron Shawn D. Ryan Thijs Heus While the total cover of broken cloud fields can in principle be obtained from one-dimensional measurements, the cloud size distribution normally differs between two-dimensional (area) and one-dimensional retrieval (chord length) methods. In this study, we use...
Wed Aug 05, 2020 03:00
Behavioral Sciences, Vol. 10, Pages 127: Customer Value Types Predicting Consumer Behavior at Dutch Grocery Retailers Behavioral Sciences doi: 10.3390/bs10080127 Authors: Kim Janssens Wim Lambrechts Henriëtte Keur Janjaap Semeijn The purpose of this paper is to profile three grocery retail formats (non-discounter, soft discounter, and hard discounter) in the Netherlands using Holbrook’s value types. These value types are linked to three consumer behavior outcomes,...
Wed Aug 05, 2020 03:00
Bioengineering, Vol. 7, Pages 87: Development of a Novel Medical Device for Mucositis and Peri-Implantitis Treatment Bioengineering doi: 10.3390/bioengineering7030087 Authors: Gloria Cosoli Lorenzo Scalise Alfredo De Leo Paola Russo Gerardo Tricarico Enrico Primo Tomasini Graziano Cerri In spite of all the developments in dental implantology techniques, peri-implant diseases are frequent (prevalence up to 80% and 56% of subjects for mucositis and peri-implantitis, respectively)...
Wed Aug 05, 2020 03:00
Biology, Vol. 9, Pages 208: Development of a New Drill Design to Improve the Temperature Control during the Osteotomy for Dental Implants: A Comparative In Vitro Analysis Biology doi: 10.3390/biology9080208 Authors: Sergio Alexandre Gehrke Raphaél Bettach Benoit Cayron Gilles Boukhris Berenice Anina Dedavid Juan Carlos Prados Frutos The present in vitro study evaluated a new drill design to improve the temperature control during the osteotomies for dental implant installation,...
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Biology, Vol. 9, Pages 207: Expanding the Limits of Computer-Assisted Sperm Analysis through the Development of Open Software Biology doi: 10.3390/biology9080207 Authors: Jesús Yániz Carlos Alquézar-Baeta Jorge Yagüe-Martínez Jesús Alastruey-Benedé Inmaculada Palacín Sergii Boryshpolets Vitaliy Kholodnyy Hermes Gadêlha Rosaura Pérez-Pe Computer assisted sperm analysis (CASA) systems can reduce errors occurring in manual analysis. However, commercial CASA systems...
Wed Aug 05, 2020 03:00
Biomedicines, Vol. 8, Pages 275: Neutrophil Extracellular Traps Impair Intestinal Barrier Function during Experimental Colitis Biomedicines doi: 10.3390/biomedicines8080275 Authors: Elliot Yi-Hsin Lin Hsuan-Ju Lai Yuan-Kai Cheng Kai-Quan Leong Li-Chieh Cheng Yi-Chun Chou Yu-Chun Peng Yi-Hsuan Hsu Hao-Sen Chiang Aberrant neutrophil extracellular trap (NET) formation and the loss of barrier integrity in inflamed intestinal tissues have long been associated with...
Wed Aug 05, 2020 03:00
Biomedicines, Vol. 8, Pages 274: Phospholipid Arachidonic Acid Remodeling During Phagocytosis in Mouse Peritoneal Macrophages Biomedicines doi: 10.3390/biomedicines8080274 Authors: Luis Gil-de-Gómez Patricia Monge Juan P. Rodríguez Alma M. Astudillo María A. Balboa Jesús Balsinde Macrophages contain large amounts of arachidonic acid (AA), which distributes differentially across membrane phospholipids. This is largely due to the action of coenzyme A-independent transacylase...
Wed Aug 05, 2020 03:00
Biomedicines, Vol. 8, Pages 273: Doxazosin, a Classic Alpha 1-Adrenoceptor Antagonist, Overcomes Osimertinib Resistance in Cancer Cells via the Upregulation of Autophagy as Drug Repurposing Biomedicines doi: 10.3390/biomedicines8080273 Authors: Shuhei Suzuki Masahiro Yamamoto Tomomi Sanomachi Keita Togashi Asuka Sugai Shizuka Seino Masashi Okada Takashi Yoshioka Chifumi Kitanaka Osimertinib, which is a third-generation epidermal growth factor receptor tyrosine...
Wed Aug 05, 2020 03:00
Biomolecules, Vol. 10, Pages 1149: Prediction of Potential Ionic Liquids (ILs) for the Solid–Liquid Extraction of Docosahexaenoic Acid (DHA) from Microalgae Using COSMO-RS Screening Model Biomolecules doi: 10.3390/biom10081149 Authors: Shiva Rezaei Motlagh Razif Harun Dayang Radiah Awang Biak Siti Aslina Hussain Amal A. Elgharbawy Ramin Khezri Cecilia Devi Wilfred This study performs a screening of potential Ionic Liquids (ILs) for the extraction of Docosahexaenoic...
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Biomolecules, Vol. 10, Pages 1148: Phosphate Derivatives of 3-Carboxyacylbetulin: Synthesis, In Vitro Anti-HIV and Molecular Docking Study Biomolecules doi: 10.3390/biom10081148 Authors: Krzysztof Marciniec Elwira Chrobak Aleksandra Dąbrowska Ewa Bębenek Monika Kadela-Tomanek Paweł Pęcak Stanisław Boryczka Lupane-type pentacyclic triterpenes such as betulin and betulinic acid play an important role in the search for new therapies that would be effective in controlling...
Wed Aug 05, 2020 03:00
Biomolecules, Vol. 10, Pages 1147: Recent Advances in the Biosynthesis of Carbazoles Produced by Actinomycetes Biomolecules doi: 10.3390/biom10081147 Authors: Masaya Kobayashi Tomohisa Kuzuyama Structurally diverse carbazole alkaloids are valuable due to their pharmaceutical properties and have been isolated from nature. Experimental knowledge on carbazole biosynthesis is limited. The latest development of in silico analysis of the biosynthetic gene clusters for bacterial carbazoles...
Wed Aug 05, 2020 03:00
Biomolecules, Vol. 10, Pages 1146: Functionalizable Antifouling Coatings as Tunable Platforms for the Stress-Driven Manipulation of Living Cell Machinery Biomolecules doi: 10.3390/biom10081146 Authors: Ivana Víšová Barbora Smolková Mariia Uzhytchak Markéta Vrabcová Djamel Eddine Chafai Milan Houska Matěj Pastucha Petr Skládal Zdeněk Farka Alexandr Dejneka Hana Vaisocherová-Lísalová Cells are continuously sensing their microenvironment and subsequently respond...
Wed Aug 05, 2020 03:00
Biomolecules, Vol. 10, Pages 1145: Characterisation of the Expression of Neurotensin and Its Receptors in Human Colorectal Cancer and Its Clinical Implications Biomolecules doi: 10.3390/biom10081145 Authors: Shengyang Qiu Stella Nikolaou Jie Zhu Peter Jeffery Robert Goldin James Kinross James L. Alexander Shahnawaz Rasheed Paris Tekkis Christos Kontovounisios Introduction: Colorectal Cancer (CRC) accounts for 9% of cancer deaths globally. Hormonal pathways...
Wed Aug 05, 2020 03:00
Biosensors, Vol. 10, Pages 91: Microfluidic-Based Electrochemical Immunosensing of Ferritin Biosensors doi: 10.3390/bios10080091 Authors: Mayank Garg Martin Gedsted Christensen Alexander Iles Amit L. Sharma Suman Singh Nicole Pamme Ferritin is a clinically important biomarker which reflects the state of iron in the body and is directly involved with anemia. Current methods available for ferritin estimation are generally not portable or they do not provide a fast response....
Wed Aug 05, 2020 03:00
Biosensors, Vol. 10, Pages 92: Frequency Shift of a SH-SAW Biosensor with Glutaraldehyde and 3-Aminopropyltriethoxysilane Functionalized Films for Detection of Epidermal Growth Factor Biosensors doi: 10.3390/bios10080092 Authors: Xue-Chang Lo Jen-Yu Li Ming-Tsang Lee Da-Jeng Yao The frequency shift of a shear-horizontal surface-acoustic-wave (SH-SAW) biosensor in which the concentration of biomolecule is determined by the amount of its adsorption on the sensing film was studied....
Wed Aug 05, 2020 03:00
Biosensors, Vol. 10, Pages 90: Nanoelectrode Arrays Fabricated by Thermal Nanoimprint Lithography for Biosensing Application Biosensors doi: 10.3390/bios10080090 Authors: Alessandra Zanut Alessandro Cian Nicola Cefarin Alessandro Pozzato Massimo Tormen Electrochemical sensors are devices capable of detecting molecules and biomolecules in solutions and determining the concentration through direct electrical measurements. These systems can be miniaturized to a size less than...
Wed Aug 05, 2020 03:00
Biosensors, Vol. 10, Pages 89: Fast Detection of 2,4,6-Trinitrotoluene (TNT) at ppt Level by a Laser-Induced Immunofluorometric Biosensor Biosensors doi: 10.3390/bios10080089 Authors: Martin Paul Georg Tscheuschner Stefan Herrmann Michael G. Weller The illegal use of explosives by terrorists and other criminals is an increasing issue in public spaces, such as airports, railway stations, highways, sports venues, theaters, and other large buildings. Security in these environments...
Wed Aug 05, 2020 03:00
Brain Sciences, Vol. 10, Pages 522: Feasibility of Using Intraoperative Neuromonitoring in the Prophylaxis of Dysesthesia in Transforaminal Endoscopic Discectomies of the Lumbar Spine Brain Sciences doi: 10.3390/brainsci10080522 Authors: Paulo Sérgio Teixeira de Carvalho Max Rogério Freitas Ramos Alcy Caio da Silva Meireles Alexandre Peixoto Paulo de Carvalho Jr. Jorge Felipe Ramírez León Anthony Yeung Kai-Uwe Lewandrowski (1) Background: Postoperative nerve root...
Wed Aug 05, 2020 03:00
Brain Sciences, Vol. 10, Pages 521: Non-Mydriatic Ultra-Wide Field Imaging Versus Dilated Fundus Exam and Intraoperative Findings for Assessment of Rhegmatogenous Retinal Detachment Brain Sciences doi: 10.3390/brainsci10080521 Authors: Beatriz Abadia Maria Carmen Desco Jorge Mataix Elena Palacios Amparo Navea Pilar Calvo Antonio Ferreras Background: to compare the extent of the detached retina and retinal tears location in rhegmatogenous retinal detachment (RRD) among...
Wed Aug 05, 2020 03:00
Brain Sciences, Vol. 10, Pages 520: Family Income Mediates the Effect of Parental Education on Adolescents’ Hippocampus Activation During an N-Back Memory Task Brain Sciences doi: 10.3390/brainsci10080520 Authors: Shervin Assari Shanika Boyce Mohsen Bazargan Cleopatra H. Caldwell Introduction: Hippocampus, a medial temporal lobe structure, has significant implications in memory formation and learning. Although hippocampus activity is believed to be affected by socioeconomic...
Wed Aug 05, 2020 03:00
Brain Sciences, Vol. 10, Pages 519: Hopelessness, Dissociative Symptoms, and Suicide Risk in Major Depressive Disorder: Clinical and Biological Correlates Brain Sciences doi: 10.3390/brainsci10080519 Authors: Mauro Pettorruso Giacomo d’Andrea Giovanni Martinotti Fabrizio Cocciolillo Andrea Miuli Ilenia Di Muzio Rebecca Collevecchio Valeria Verrastro Fabio De-Giorgio Luigi Janiri Massimo di Giannantonio Daniela Di Giuda Giovanni Camardese Background:...
Wed Aug 05, 2020 03:00
Brain Sciences, Vol. 10, Pages 518: Reply: Factors Influencing Central Nervous System Abnormalities in m.11778G>A Carriers Brain Sciences doi: 10.3390/brainsci10080518 Authors: Cezary Grochowski Kamil Jonak First of all, I would like to thank the reader for their interest and taking the time to analyze our work [...]
Wed Aug 05, 2020 03:00
Brain Sciences, Vol. 10, Pages 517: Whole-Language and Item-Specific Inhibition in Bilingual Language Switching: The Role of Domain–General Inhibitory Control Brain Sciences doi: 10.3390/brainsci10080517 Authors: Judy D. Zhu Paul F. Sowman A prominent theory of bilingual speech production holds that appropriate language selection is achieved via inhibitory control. Such inhibition may operate on the whole-language and/or item-specific level. In this study, we examined these two levels...
Wed Aug 05, 2020 03:00
Cancers, Vol. 12, Pages 2185: The Role of Necroptosis in ROS-Mediated Cancer Therapies and Its Promising Applications Cancers doi: 10.3390/cancers12082185 Authors: Sheng-Kai Hsu Wen-Tsan Chang I-Ling Lin Yih-Fung Chen Nitin Balkrushna Padalwar Kai-Chun Cheng Yen-Ni Teng Chi-Huei Wang Chien-Chih Chiu Over the past decades, promising therapies targeting different signaling pathways have emerged. Among these pathways, apoptosis has been well investigated and targeted...
Wed Aug 05, 2020 03:00
Cancers, Vol. 12, Pages 2188: YB-1 Mediates TNF-Induced Pro-Survival Signaling by Regulating NF-κB Activation Cancers doi: 10.3390/cancers12082188 Authors: Aneri Shah Carlos Plaza-Sirvent Sönke Weinert Jörn H. Buchbinder Inna N. Lavrik Peter R. Mertens Ingo Schmitz Jonathan A. Lindquist Cell fate decisions regulating survival and death are essential for maintaining tissue homeostasis; dysregulation thereof can lead to tumor development. In some cases, survival and...
Wed Aug 05, 2020 03:00
Cancers, Vol. 12, Pages 2189: Therapeutic Zfra4-10 or WWOX7-21 Peptide Induces Complex Formation of WWOX with Selective Protein Targets in Organs that Leads to Cancer Suppression and Spleen Cytotoxic Memory Z Cell Activation In Vivo Cancers doi: 10.3390/cancers12082189 Authors: Wan-Pei Su Wan-Jen Wang Jean-Yun Chang Pei-Chuan Ho Tsung-Yun Liu Kuang-Yu Wen Hsiang-Ling Kuo Yu-Jie Chen Shenq-Shyang Huang Dudekula Subhan Yu-An Chen Chen-Yu Lu Chia-Yun Wu Sing-Ru...
Wed Aug 05, 2020 03:00
Cancers, Vol. 12, Pages 2186: SARS-CoV-2 Infection and Lung Cancer: Potential Therapeutic Modalities
Cancers, Vol. 12, Pages 2186: SARS-CoV-2 Infection and Lung Cancer: Potential Therapeutic Modalities Cancers doi: 10.3390/cancers12082186 Authors: Ishita Gupta Balsam Rizeq Eyad Elkord Semir Vranic Ala-Eddin Al Moustafa Human coronaviruses, especially SARS-CoV-2, are emerging pandemic infectious diseases with high morbidity and mortality in certain group of patients. In general, SARS-CoV-2 causes symptoms ranging from the common cold to severe conditions accompanied by...
Wed Aug 05, 2020 03:00
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