Successfull treatment of Saksenaea sp. osteomyelitis by conservative surgery and intra-diaphysal incorporation of amphotericin B cement beads. [Clinical Therapeutics]

Osteoarticular mucormycosis are quite rare and challenging infections mostly due to direct inoculation during traumatic injury in immunocompetent patients. Their classical management includes a combination of aggressive surgical debridement that may lead to amputation and long-term systemic liposomal amphotericin B therapy. This article describes successful treatment of a Saksenaea sp. osteomyelitis in a patient with diabetes mellitus with a combination of systemic antifungal agents and a conservative surgery with insertion of amphotericin-impregnated cement beads.

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