Ph'+ acute lymphoblastic leukemia (Ph'+-ALL) is an oncohematologic disorder for which allogeneic bone marrow transplantation still offers the only chance of cure. However, relapse is the main reason for treatment failure, also after hematopoietic stem cell transplantation (HSCT). New drugs, such as third generation tyrosine kinase inhibitors (TKIs) and monoclonal antibodies, have expanded the therapeutic landscape, especially in patients who relapsed before HSCT. Very few reports, up to now, have described the use of both classes of these new agents in combination with donor lymphocyte infusions (DLI) in the setting of patients who relapsed after HSCT. We report on a young patient affected by Ph'+-ALL, who relapsed after the second HSCT and who reached molecular remission and long-term disease control by treatment with the anti-CD22 monoclonal antibody inotuzumab ozogamicin, DLI, and the 3rd generation TKI ponatinib.
Chemotherapy 2018;63:220–224
https://ift.tt/2Az8dVp
Αρχειοθήκη ιστολογίου
-
►
2023
(138)
- ► Φεβρουαρίου (74)
- ► Ιανουαρίου (64)
-
►
2022
(849)
- ► Δεκεμβρίου (61)
- ► Σεπτεμβρίου (74)
- ► Φεβρουαρίου (65)
-
►
2021
(2936)
- ► Δεκεμβρίου (59)
- ► Σεπτεμβρίου (180)
- ► Φεβρουαρίου (325)
-
►
2020
(1624)
- ► Δεκεμβρίου (293)
- ► Σεπτεμβρίου (234)
- ► Φεβρουαρίου (28)
-
►
2019
(13362)
- ► Δεκεμβρίου (19)
- ► Σεπτεμβρίου (54)
- ► Φεβρουαρίου (5586)
- ► Ιανουαρίου (5696)
-
▼
2018
(66471)
- ► Δεκεμβρίου (5242)
-
▼
Οκτωβρίου
(6225)
-
▼
Οκτ 29
(182)
- Economic Consequences of Investing in Anti-HCV Ant...
- Cavitary Pulmonary Nodules in an Immunocompromised...
- In the Literature
- News
- Cover
- Clostridium difficile infection perceptions and pr...
- The effects on thermal lesion shape and size from ...
- Gene-Environment Interplay in Child Eating Behavio...
- Genetics of anophthalmia and microphthalmia. Part ...
- Aurobindo Pharma Limited Issues Voluntary Recall o...
- Rhythmic auditory cues shape neural network recrui...
- Aurobindo Pharma Limited Issues Voluntary Recall o...
- A case of Alemtuzumab-induced neutropenia in multi...
- No polymorphisms in K13-propeller gene associated ...
- Blood-borne and sexually transmitted infections: a...
- Quality control implementation for universal chara...
- Fomite-mediated transmission as a sufficient pathw...
- PPM1D Functions as Oncogene and is Associated with...
- A Mathematical Model of How People Solve Most Vari...
- Is Syntax Semantically Constrained? Evidence From ...
- Prognostic Significance of Anatomic Origin and Eva...
- Predominance of triple wild-type and IGF2R mutatio...
- Phenomic Selection Is a Low-Cost and High-Throughp...
- Training Population Optimization for Prediction of...
- Albumin infusion in spontaneous bacterial peritoni...
- Hemodynamic support in the early phase of septic s...
- Practical approach to diastolic dysfunction in lig...
- Fluoroscopy-guided simultaneous distal perfusion a...
- Loss of GAS5 tumour suppressor lncRNA: an independ...
- WT1 expression in vessels varies with histopatholo...
- Successfull treatment of Saksenaea sp. osteomyelit...
- Vaginal gel component hydroxyethyl cellulose signi...
- Ceftobiprole Activity against Gram-Positive and -N...
- In Vitro Activity of Plazomicin against Gram-negat...
- In Vivo Efficacy of Humanized WCK 5222 (Cefepime-Z...
- Applying Rapid Whole Genome Sequencing to Predict ...
- Single-dose Pharmacokinetics, Excretion, and Metab...
- Zidovudine-mediated autophagy inhibition enhances ...
- Azidothymidine produces synergistic activity in co...
- Inhibition of Cytomegalovirus Replication with Ext...
- Preclinical Characterization of NVR 3-778, a First...
- Miltefosine reduces the cytolytic activity and vir...
- Emergence of resistance to macrolides and rifampic...
- Spontaneous mutational frequency and FKS mutation ...
- Population pharmacokinetic model and limited sampl...
- Outcomes by Minimum Inhibitory Concentrations for ...
- Use of Translational PK/PD Infection Models to Und...
- Efficacy of azithromycin and miltefosine in experi...
- Optimization of cellulase production under solid‐s...
- Low Levels of Flu Reported in U.S. From May to Oct...
- Prospective Genotyping of Hepatocellular Carcinoma...
- A Novel Engineered Small Protein for Positron Emis...
- Ibrutinib therapy releases leukemic surface IgM fr...
- Fetal/Neonatal Pericardial Effusion in Down's Synd...
- Clinical Insights for Cervical Ripening and Labor ...
- Importance of Individual Elements for Perineal Pro...
- Comparison of Birth Outcomes by Gestational Diabet...
- Early-Onset Neonatal Sepsis with Extended Spectrum...
- Fetal MRI in the Identification of a Fetal Ventral...
- An Out-of-Season Case of Coxsackie B Myocarditis w...
- Loss of GAS5 tumour suppressor lncRNA: an independ...
- WT1 expression in vessels varies with histopatholo...
- Radiation Dose-Response For Risk Of Myocardial Inf...
- Coronary flow reserve in patients with Primary Bil...
- ERECTILE DYSFUNCTION IN COMPENSATED LIVER CIRRHOSIS
- Endosheath ultrathin transnasal endoscopy is a cos...
- Physical–Mental Comorbidity of Pediatric Migraine ...
- PCORnet Bariatric Surgery Outcomes: Strength in Nu...
- Clinical Outcomes Associated With Sickle Cell Trai...
- Reducing Firearm Injuries and Deaths in the United...
- Expanding the Public Health Approach to Gun Violen...
- What Can I Do as a Physician to Prevent Firearm In...
- On-Demand Sildenafil as a Treatment for Raynaud Ph...
- Comparative Effectiveness and Safety of Bariatric ...
- Public Perceptions of Firearm- and Non–Firearm-Rel...
- Effectiveness and Safety of Bariatric Procedures f...
- Interventions for Preventing Thromboembolic Events...
- The Gut Microbiome and Digestive Health – A New Fr...
- Egg yolk immunoglobulin interactions with Porphyro...
- Introduction: Special Issue—The Origins of Macroph...
- Paramedic Chief Digital: How to improve patient an...
- A Loop-mediated Isothermal Amplification (LAMP) As...
- Rapid Response: Is EMS response different when the...
- Cognitive load and emotional processing in psorias...
- Quantitative Analysis by Thermogravimetry-Mass Spe...
- Preclinical evaluation of PSMA expression in respo...
- Integrate Imaging Flow Cytometry and Transcriptomi...
- Paid Family Leave Policies May Modestly Increase B...
- Hypofractionated Radiation OK for Localized Prosta...
- Nurse-Led Care Efficacious, Cost-Effective for Gout
- Odds of Overweight/Obesity Up for Children With Au...
- ASN: Kidneys Transplanted in France Would Be Disca...
- Durvalumab Extends Survival in Stage III Non-Small...
- ASN: Home Dialysis Associated With Improved Survival
- Smoking Associated With Head, Neck Surgery Complic...
- Healthier Diet Tied to Lower Mortality Risk in CRC...
- In Complicated UTI, Cefiderocol Noninferior to Imi...
- A Method to Study Adaptation to Left-Right Reverse...
- Verification of the diagnostic strategy for anteri...
- Lentinan inhibits tumor angiogenesis via interfero...
-
▼
Οκτ 29
(182)
- ► Σεπτεμβρίου (5478)
- ► Φεβρουαρίου (4835)
- ► Ιανουαρίου (5592)
-
►
2017
(44259)
- ► Δεκεμβρίου (5110)
- ► Σεπτεμβρίου (5105)
-
►
2016
(7467)
- ► Δεκεμβρίου (514)
- ► Σεπτεμβρίου (1038)
- ► Φεβρουαρίου (793)
Αναζήτηση αυτού του ιστολογίου
Δευτέρα 29 Οκτωβρίου 2018
Long-Term Molecular Remission Achieved by Antibody Anti-CD22 and Ponatinib in a Patient Affected by Ph’+ Acute Lymphoblastic Leukemia Relapsed after Second Allogeneic Hematopoietic Stem Cell Transplantation: A Case Report
Εγγραφή σε:
Σχόλια ανάρτησης (Atom)
-
Αλέξανδρος Γ. Σφακιανάκης Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,0030693260717...
-
heory of COVID-19 pathogenesis Publication date: November 2020Source: Medical Hypotheses, Volume 144Author(s): Yuichiro J. Suzuki ScienceD...
-
https://ift.tt/2MQ8Ai8
Δεν υπάρχουν σχόλια:
Δημοσίευση σχολίου
Σημείωση: Μόνο ένα μέλος αυτού του ιστολογίου μπορεί να αναρτήσει σχόλιο.