Outcomes of Patients with Sinonasal Squamous Cell Carcinoma Treated with Particle Therapy Using Protons or Carbon Ions

We investigated outcomes of patients with sinonasal squamous cell carcinoma (SCC) treated only with particle therapy; i.e., proton therapy (PT) or carbon ion therapy (CIT). In this largest retrospective study of its kind to date, PT and CIT were effective against sinonasal SCC, with no significant difference in outcomes between the two modalities and few toxicities. These data suggest an important role for these modalities in SCC treatment.

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