Update: Can Newer Rapid Influenza Tests Rule Out Disease?

Of the 162 studies included for full-text review, 38 were excluded for not reporting influenza A and B results separately, leaving 124 articles for quantitative analysis. Overall, the new rapid influenza tests, digital immunoassays, and rapid nucleic acid amplification tests demonstrated strikingly higher sensitivities for influenza A and B compared with the more traditional rapid influenza diagnostic tests. The pooled sensitivities varied widely between test types (ranging from 53% to 95%), whereas the pooled specificities were consistently greater than 98.3%.

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