Radiation Therapy to Sites of Metastatic Disease as Part of Consolidation in High-risk Neuroblastoma: Can Long-term Control be Achieved?

Although radiation therapy to persistent sites of metastatic disease is recommended as part of consolidative therapy for high-risk neuroblastoma, there is little data evaluating the value of this approach in achieving long-term control. Our results show that irradiation of metastatic sites of disease is effective in achieving local control, and that response to induction chemotherapy is a significant prognostic factor for control at irradiated sites.

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