Chronic pulmonary insufficiency of prematurity: definitions matter

In 1967, Northway et al described the clinical and histologic features of lung injury and repair in infants with prior histories of respiratory distress syndrome and coined a new term, "bronchopulmonary dysplasia," to describe these findings (N Engl J Med 1967;16:357-68). Since that time, the age of viability has decreased, and management has evolved with increasing use of non-invasive ventilation. Although we now recognize a broader spectrum of pulmonary problems in preterm infants, children, and adults, we continue to define chronic lung disease as the need for supplemental oxygen at a single point in time.

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