Towards personalized dosimetry with 32P microparticle therapy for advanced pancreatic cancer

A Monte Carlo particle simulation platform was developed to model the dosimetry of 32P microparticle internal radionuclide treatment for advanced pancreatic cancer. Patient-specific dosimetry simulations based on data from previous 32P microparticle clinical studies demonstrated the importance of considering non-uniform dose distributions as well as relative dynamic changes in tumor volume and dose rate during treatment. These results will be valuable in designing future personalized treatment strategies.

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