Development and internal validation of a clinical risk score to predict pain response after palliative radiotherapy in patients with bone metastases

Radiotherapy is effective in reducing pain in about 60% of patients with bone metastases. We developed a prediction model to help identify patients who are unlikely to respond to palliative radiotherapy. Primary tumor site, performance status, and baseline pain score were associated with pain response, and were modestly able to discriminate good and poor responders.

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