Reduced-dose Radiation Therapy to the Primary Site is Effective for High-risk Neuroblastoma: Results from a Prospective Trial

We developed a prospective radiation dose-reduction protocol for patients with high-risk neuroblastoma, with the goal of maintaining disease control while reducing late morbidity. We found that dose reduction from 21 Gy to 18 Gy after gross total resection did not compromise local control or survival outcomes in our cohort of 25 patients with high-risk neuroblastoma.

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