Muscle Satellite Cell Cross-Talk with a Vascular Niche Maintains Quiescence via VEGF and Notch Signaling

Verma et al. performed skeletal muscle tissue clearing and unbiased fluorescent image analysis to show that muscle stem cells (satellite cells) pattern the microvasculature to be in close proximity to them via VEGFA. In turn, this juxtavascular niche keeps the satellite cells in a more quiescent state, suggesting a beneficial cross-talk.

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