Long term follow up of patients treated at a single institution using a passively scattered proton beam; observations around the occurrence of second malignancies.

To analyze the occurrence of secondary malignancies after passively scattered proton beam therapy by way of a retrospective study of patients with long term follow up treated for intracranial and cranial pathologies. The occurrences of out of field secondary malignancies were compared with the expected incidence in the general population based on national cancer statistics. No increased risk was observed for all age groups studied, and only one in field secondary malignancy was observed.

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