Chromoendoscopy: adding color to duodenal polyps

Adenomatous polyposis syndromes, such as familial adenomatous polyposis (FAP) and MUTYH-associated polyposis (MAP), are well-characterized inherited conditions resulting from germline mutations in the APC and MUTYH genes, respectively. These mutations predispose an individual to colonic and extracolonic malignancies; if they are left untreated, the risk of colorectal cancer (CRC) in FAP is nearly 100%. The most common cause of extracolonic cancer mortality in affected persons is duodenal or ampullary cancer.

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