Mantle Cell Lymphoma Presenting as Colonic Lymphomatous Polyposis

A 60-year-old man presented with a 2-month duration of intermittent hematochezia and weight loss. There was no similar illness among family members. The physical examination was essentially normal. Laboratory tests showed essentially normal study with the exception of mild anemia and a high lactate dehydrogenase level (765 U/L; normal range, 125–300 U/L). Colonoscopy showed multiple nodular lesions in the rectum (Figure A), sigmoid colon, and cecum. A computed tomography of the abdomen showed irregular, nonenhancing, mucosal thickening in the rectum, sigmoid colon (Figure B), and ileocecal region.

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