Treatment of thrombocytopenic patients with GI bleeding

The treatment of patients with thrombocytopenia who require endoscopy is variable and uncertain, with limited evidence to inform decisions. In addition, the treatment might vary depending on the category of thrombocytopenia. Thrombocytopenia may be due to sequestration (eg, portal-hypertension–induced splenomegaly), reduced production (eg, hematologic disorders, chemotherapy), or increased destruction (eg, immune thrombocytopenia).

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